Lrea018243.1
Basic Information
- Insect
- Leptidea reali
- Gene Symbol
- -
- Assembly
- GCA_949711725.1
- Location
- CATIXN010000014.1:17113775-17131914[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.47 59 5.5 0.3 1 23 165 187 165 187 0.96 2 13 0.012 1.5 10.5 2.6 1 23 194 216 194 216 0.98 3 13 0.8 1e+02 4.8 0.9 1 15 220 234 220 243 0.84 4 13 0.00022 0.028 16.0 1.4 1 23 248 271 248 271 0.95 5 13 0.00017 0.021 16.3 0.7 2 23 278 299 277 299 0.97 6 13 0.0001 0.013 17.1 6.7 2 23 310 331 310 331 0.97 7 13 0.0026 0.32 12.6 0.1 2 23 338 360 337 360 0.92 8 13 3.9e-05 0.0048 18.4 6.2 2 23 373 395 372 395 0.97 9 13 0.00068 0.085 14.4 1.9 1 23 402 425 402 425 0.96 10 13 0.0078 0.98 11.1 0.1 5 23 435 454 433 454 0.93 11 13 2.8e-05 0.0035 18.8 0.5 3 23 465 485 464 485 0.96 12 13 1.2e-06 0.00015 23.1 0.5 1 23 490 513 490 513 0.97 13 13 2.7e-06 0.00034 22.0 1.0 1 23 547 570 547 570 0.97
Sequence Information
- Coding Sequence
- ATGGAGACAATAGTTAAAATTGAACGGGAAGATGAACCAGAAGATAACATAGACACAGAAACCTCAGTCGCTATTAAAACGGAACCCGATGATGACACTGAAATAAATGTGTCTTCGGATTTTAAGATACCAGAAACCCTAATTAGTAATGATGAGTCTGGCGACAAGAAGTCATCTAAACCAATTAAAATGGAGTCTGTACTGAATGTTGAATGTGTAATAGCCGAAGATAAAAAACTAGATAAAGGATCAACATCAGAATCcgcaaaaaagaaaaagaacagGAACCCTATAAttcaaagaagaaaaaaaatattgatatcagATGATGAGTGGGAACCTGAGAAGAAAGAAACATCAGAACAAAGTGGCTCACagaAAGTAAATGACTATGCATACAGTGCACTCAGTCAGATAGAGATAGTGACAATAACAGAAGAGGAGAGACAGATAGAGTTCCAAGAGTTGTATGAATCCCGAAAACATATGAATCATATTTGTAATAAGTGTGCTATCGGCTATGTTATCAAGGAGGCATATGATATGCATATGAAGATGCATTCTCCGgagtCCGGGTCTTACGTGTGCTCGCTATGTGACACGTACCTAAAGACGGAAGAAACGCTGCACCGTCACAAACTGCGTCATTACCGCCGCTACCGTTGCATGGTGTGCGGAGTGCGCTACAAGGACCGTGACGCGTGCGCAGGACACGTGTCGTTCTCGCACGCCGGCACAACCTTCCGCTGCGACCAGTGCACCTCAGAATTcaaACGTCCGCAATACTTGAAGCGGCACATAGAACAGATGCATCTGAAGGCCAACCCGATGGAGTGTCCTGTCTGCCACCAGGTGTTCTATGAGAGTGGTTGGTTCCGAAACCACGTGAGGAAGCACAACAAAGAAGTGCAAGAGTCGAAGCAAGCGTCGTGTCCGGTGTGCCACCGTCACTTCAAACACAAGTCGTACCTGCGCCAACACCTGCTGGTGCACCGAGCCGCTCGGGACGTGACCTGCCCGGAGTGCTCCGAGGTCTTCATCAACTCGCATCTCCTCGACCTGCACTACGAGGAGGCTCACAAGGACAACTTTGTCGTACATCCGGAGGTGGAGCAACGTTGCCAACACTGTCAGAGAACATTCGAGACTCGTGCCAACCTGCACCGACACATGCAGCGAATGCACACGGACGGCGCCAAACGGTACCAGTGCGAGCACTGCAAGCGCATGTACTTCTCGAAGGGCGAGGTGCGCTCGCACATCATGTGGTCGCACCTGCAGCACGCGGGCGGACACCCGTGCACGTGCGGCCGCATGTTCCGCACGCCCGTGCGCCTGCGGGAACACATCGCCGTCAAACACCTGGGTGCCGTGCCGCCGCGCGACAAACACTGCCCTATCTGCGACAAGGCCTTTGCAaaCCAGCAAGTATTGACACGACATGTTAAGGGCCACAAGGGCGAGTTGTATCCGTGTACGGAGTGCGGGCGCACCTTCCGTACGCAGTCATACGTGAAGGTGCACTACCAGATCGTGCACCTACACATGACGCGCTCCGAGATACGACGGCAGCGCCGCAGGAAGCTGATCATGGTGCCCGACGCCGCGGAGGAGTCGCAGCAAGACTTCGACGAAGAGTTCCCGTGCGTTGAGTGTGGCAAGACATTCAAGACGCAGTCTTACGTGAAGGTCCACTACAACATGAAGCACCGCAACATGTCGCGCGAGGAAGCCAAGCGGAGGAGCAAGGAGCTGAACGTGGCCGACGTGGTGGGGCCCCGCCTCGAGCAGGTGTTCGTCAAGACGGAGCCCCAGGAGGCCCTCGCAGTGCCCATGTTCGAGACCTTCGTGGATATACAGAGGGAGTACTCTTAA
- Protein Sequence
- METIVKIEREDEPEDNIDTETSVAIKTEPDDDTEINVSSDFKIPETLISNDESGDKKSSKPIKMESVLNVECVIAEDKKLDKGSTSESAKKKKNRNPIIQRRKKILISDDEWEPEKKETSEQSGSQKVNDYAYSALSQIEIVTITEEERQIEFQELYESRKHMNHICNKCAIGYVIKEAYDMHMKMHSPESGSYVCSLCDTYLKTEETLHRHKLRHYRRYRCMVCGVRYKDRDACAGHVSFSHAGTTFRCDQCTSEFKRPQYLKRHIEQMHLKANPMECPVCHQVFYESGWFRNHVRKHNKEVQESKQASCPVCHRHFKHKSYLRQHLLVHRAARDVTCPECSEVFINSHLLDLHYEEAHKDNFVVHPEVEQRCQHCQRTFETRANLHRHMQRMHTDGAKRYQCEHCKRMYFSKGEVRSHIMWSHLQHAGGHPCTCGRMFRTPVRLREHIAVKHLGAVPPRDKHCPICDKAFANQQVLTRHVKGHKGELYPCTECGRTFRTQSYVKVHYQIVHLHMTRSEIRRQRRRKLIMVPDAAEESQQDFDEEFPCVECGKTFKTQSYVKVHYNMKHRNMSREEAKRRSKELNVADVVGPRLEQVFVKTEPQEALAVPMFETFVDIQREYS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00874701; iTF_00876436;
- 90% Identity
- iTF_00874701;
- 80% Identity
- -