Lrea021927.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leptidea reali
Gene Symbol
-
Assembly
GCA_949711725.1
Location
CATIXN010000018.1:6095981-6132098[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 7.1e-05 0.0088 17.5 1.5 1 23 428 450 428 450 0.97
2 20 0.00037 0.047 15.3 1.0 1 20 456 475 456 478 0.94
3 20 0.0012 0.15 13.7 4.8 1 23 497 519 497 519 0.98
4 20 7.8e-05 0.0098 17.4 5.7 1 23 525 547 525 547 0.99
5 20 5.3e-05 0.0066 17.9 5.1 1 23 553 575 553 575 0.97
6 20 6.9e-07 8.6e-05 23.9 5.2 1 23 581 603 581 603 0.98
7 20 1.2e-05 0.0015 19.9 2.8 1 23 609 631 609 631 0.97
8 20 9.7e-05 0.012 17.1 6.7 1 23 637 659 637 659 0.97
9 20 4.3e-05 0.0054 18.2 4.8 1 23 665 687 665 687 0.97
10 20 4.6e-07 5.8e-05 24.4 1.9 1 23 693 715 693 715 0.98
11 20 4.5e-05 0.0056 18.2 8.1 1 23 721 743 721 743 0.98
12 20 2.3e-07 2.8e-05 25.4 6.7 1 23 749 771 749 771 0.98
13 20 3.5e-06 0.00044 21.6 0.8 1 23 778 800 778 800 0.98
14 20 2.6e-05 0.0032 18.9 6.9 1 23 806 828 806 828 0.97
15 20 2.9e-05 0.0036 18.8 7.1 1 23 834 856 834 856 0.98
16 20 2.4e-07 3e-05 25.3 3.2 1 23 862 884 862 884 0.99
17 20 8.4e-06 0.0011 20.4 8.0 1 23 890 912 890 912 0.97
18 20 9.4e-06 0.0012 20.3 4.4 1 23 918 940 918 940 0.97
19 20 0.00052 0.065 14.8 0.3 1 23 947 969 947 969 0.96
20 20 0.047 5.9 8.7 5.4 1 23 977 999 977 999 0.99

Sequence Information

Coding Sequence
ATGAATCAGGATCACCACAGTATCAGTGGAGGTAGTGGACAGACTTCAACCAATTCAGAGGGCCAAAGAGTACAATCTGGCCAGCAACAACAGCAAGCCCCAACCACTTCTGCAACAGACCTAAGAGTTAACTCGGCAGTAAATGTTGCGTTATCGAGCGTTGCCAAGTACTGGGTGTTTACAAATTTGTTTCCCGGTCCAATACCACAAGTCTCTCTGTATGGGCTACCTGCAAGCACTAGAATTGAAAATGGGAAACCTGTACAGGATCTTGGCCAATCACATGCTAGCTTACTTAATGGTGATCCTAATATTATTCTGGGACATCATAGTGCTCAACCACAAGTTACAGTGTCAGCCGCTGGGGGTCAACAAATACCTATATCTCAATTAATTACTACTCAGTCTGGACAAGGACATGATTCTCTGGTGTCCCATAGTCAACAAGAAATGTCCTCACAACAGAACTCAAGTAGTTCTCAAGTGACTGTTAACTCTCAGTCAGCCCATCAACAGCCCAGTAATCGCCTGGAGTTTGTGCAACATCATGGCTTAGATATgggtcATCATACACAAAATCATTTGTTGCAACAACAACTTCTAGCAGCAACAAGACCCGAACATTCCAACCAACagATTCAACTTACTGTGAGTGAGGATGGCATCGTAACAGTTGTGGAACCTGGCAGCAGCAAGTTGATGGAAAAGGACGATCTCCATGATTCCATCAAAATGCCTTCGGACCACACCCTCACTGTGCATCAGTTGCAACAGATTGTGGGACACCACCAGGTCATAGACAGTGTGGTCCGTATAGAGCAGGCTACCGGAGAACCTGCCAACATACTAGTGACTCAGAACCCAGATGGCACCACGTCGATAGAGACGAGCGCCGCTGACTCCCTCATTGTAAAAGATGAGAAGAATGTTAAAATTGAATCTGCACAGTATGCTGCGGCTTCGGATATTAAGGAAATTAAAGGAATTGATTTGAAGAGTGTTGGTGCAATGGGTATGGAAGGGGCTGTAGTGAAGATATCGGGAGGTGGCACAGACAATGATATGCATGCCATGTACAAGGTGAATGTGGAGGACCTATCACAACTCCTAGCCTACCATGAGGTGTTTGGAAAACTCAATACAGATTCCCAGCAAACACAGCAGGCGCAGACACCACCACAACAGCCACAAGCTAAGCAGCCAGTGATGTACCAAGTGGACGTAGAAGCCAGTACGAGCGCATCTGCGACGCTCCCCGACACGGAGTCATCTTCCGGGCCACACCCATGTGACCTCTGCAATAAGATATTCGCCTACCGCTATCAGCTTATTGTACatagGCGCTATCATGGTGAAAATAAACCTTACACCTGTCAAGTTTGCGGCCAGGCATTCGCCAATCCGACGGAACTGTCTAAACATGGAAAATGTCACCTTGCTGGCGAATCAGCGGAACGTCAAGCAAAGCGATTGGCTCAAGACAAGCCTTACGCGTGCTCCACGTGCCACAAGACGTTCTGGAGGAAGGAGCACCTGGACAATCACGTGCGCACACACACCGGGGAAACTCCATACagATGTCAGTTCTGCTCCAAAACGTTCACGCGCAAGGAACACATGGTGAACCACGTGCGGAAACATACGGGCGAGACTCCGCATCGGTGCGATATCTGTAAGAAGAGTTTCACTAGGAAGGAGCACTTCTTGAACCACGTCATGTGGCACACagGTGAAACGCCGCACCAATGTCAAATTTGCGGCAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCATATGCGATCGCATACGAACGACACGCCGTTCAGATGCGAACTGTGCAGCAAGGCCTTCACCAGAAAGGAACATTTCACCAACCACATATTGTGGCACTCGGGTGAGACACCGCACCGTTGCGACTTCTGCTCGAAGACGTTCACCCGCAAGGAGCACCTCCTGAACCACGTGCGGCAACACACAGGCGAGTCGCCTCACCGCTGCGACTACTGCGCCAAGTCGTTCACGCGGAGGGAACACCTCGTCAACCACGTGCGCCAACACACCGGCGAGACGCCCTTCCAGTGTGGCTACTGTCCTAAGGCATTTACTAGGAAGGACCATCTGGTGAACCACGTCCGGCAGCACACAGGCGAGTCGCCACATAAGTGCACGTTTTGCACCAAGTCGTTCACGCGCAAGGAGCACCTCACTAACCACGTGCGGCAGCACACGGGAGAGTCTCCGCACCGATGCACCTACTGCGGCAAGTCCTTCACCAGGAAGGAGCATCTCACCAACCACATAAGACAGCATACGGGCGAGAGTCCTCCACACAAGTGCTCGCTGTGCCCGCGCGCGTTCGTGCGCAAGGAGCAACTCAACGTGCACGTGCGCGTGCATACGGGCGAATCGCCGCACGTTTGCTCCTACTGTAACAAGAATTTCACGAGGAAAGAGCATCTTAAGAACCATGAGAGACAACATACAGGCGAGACCCCGTTCAAGTGCACTTTCTGCACCAAGGCGTTCTCCCGCAAGGAACACCTGACCAACCACATGCACCTTCACACAGGAGAGACGCCCTACAAGTGTCCTTTCTGCACCAAGGTGTTCTCCAGGAAGGAACATCTGACCAACCATGTTCGGATACACACGGGCGAGTCGCCGCACCGCTGCGAGTTCTGCAACAAGACGTTCACGCGCAAGGAGCACCTCACCAACCACATGAAGCAGCACACGGGTGACGCGCCGCACTCGTGCAAGGTGTGCTCCAAGTCCTTCACCAGGAAGGAGTTCCTCGTCACGCACATGAGATCGCACAGTTGCGGCGAGCGGCCGTACAGTTGCGGGGAATGCGGCAAGTCATTCCCGTTGAAGGGCAATCTGCTGTTCCACGAACGGTCACACAACAAGGGCAACAACAAAGTATTCAAATGTGACATCTGTTCTAAAGATTTTATGTGTAAAGGTCATCTTGTGACGCATCGTCAGACGCACGTCGACGCACCCGAGAACAGCCAGGCTGGGGAGCCGCTCATTGATGCCAGTGATGTGAGCACCGCTGAATGCAAAGATCAACTCGACGGAGAGCGGAAACCAGATGTGGTGATAAGCGAAGCTACGACTGGCAGTGCGCCCTGTGTGGAGTCTGGAGACTTGCCGGGCTGGCGACGTCGCCAGTATAATATAGACGCCAAGACTGACGAATCCGTATTTGTGGAAAGACTTGAGTTTCGATACACAAAACTTCAGAGGGTAGCCACTGGCTACTTCCATTTGGCGACCGAAGGTAGCCAAGCCTACATAGCCGGCGACTTCGCCATGGCATCTCGGTGA
Protein Sequence
MNQDHHSISGGSGQTSTNSEGQRVQSGQQQQQAPTTSATDLRVNSAVNVALSSVAKYWVFTNLFPGPIPQVSLYGLPASTRIENGKPVQDLGQSHASLLNGDPNIILGHHSAQPQVTVSAAGGQQIPISQLITTQSGQGHDSLVSHSQQEMSSQQNSSSSQVTVNSQSAHQQPSNRLEFVQHHGLDMGHHTQNHLLQQQLLAATRPEHSNQQIQLTVSEDGIVTVVEPGSSKLMEKDDLHDSIKMPSDHTLTVHQLQQIVGHHQVIDSVVRIEQATGEPANILVTQNPDGTTSIETSAADSLIVKDEKNVKIESAQYAAASDIKEIKGIDLKSVGAMGMEGAVVKISGGGTDNDMHAMYKVNVEDLSQLLAYHEVFGKLNTDSQQTQQAQTPPQQPQAKQPVMYQVDVEASTSASATLPDTESSSGPHPCDLCNKIFAYRYQLIVHRRYHGENKPYTCQVCGQAFANPTELSKHGKCHLAGESAERQAKRLAQDKPYACSTCHKTFWRKEHLDNHVRTHTGETPYRCQFCSKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFLNHVMWHTGETPHQCQICGKKYTRKEHLVNHMRSHTNDTPFRCELCSKAFTRKEHFTNHILWHSGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCDYCAKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCTFCTKSFTRKEHLTNHVRQHTGESPHRCTYCGKSFTRKEHLTNHIRQHTGESPPHKCSLCPRAFVRKEQLNVHVRVHTGESPHVCSYCNKNFTRKEHLKNHERQHTGETPFKCTFCTKAFSRKEHLTNHMHLHTGETPYKCPFCTKVFSRKEHLTNHVRIHTGESPHRCEFCNKTFTRKEHLTNHMKQHTGDAPHSCKVCSKSFTRKEFLVTHMRSHSCGERPYSCGECGKSFPLKGNLLFHERSHNKGNNKVFKCDICSKDFMCKGHLVTHRQTHVDAPENSQAGEPLIDASDVSTAECKDQLDGERKPDVVISEATTGSAPCVESGDLPGWRRRQYNIDAKTDESVFVERLEFRYTKLQRVATGYFHLATEGSQAYIAGDFAMASR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00771241;
90% Identity
iTF_00876408;
80% Identity
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