Basic Information

Insect: Leptidea juvernica
Gene Symbol: Baz2b
Assembly: GCA_949711685.1
Location: CATIXL010000017.1:2673971-2739936[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.8e-10 2.4e-06 28.3 0.0 5 74 615 687 612 690 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.8e-10	2.4e-06	28.3	0.0	5	74	615	687	612	690	0.85

Sequence Information

Coding Sequence: ATGGACAAGGAGAGCGGGGACGGTGGCGATTCGACCGCCAAGCCTCCGCCCGATCCCCTACTCGACCCCTCGTCACTCTTTGGAGCGTACTGGGGACGTGATGGCGGCGCGAGTTCGGCGCAGGCTCAAGCCCAGGCGCAGGCGGCGTTGTTTGGCTTCGGATCGAGATACCCTGCCCCCTCCACTCTGGGAGTCGCCGCCAACCAGGCCGCCTCGCTTGGACTACACCCCGCTGCCAGTGCAGCATGGTGGTCAATGGCGTCTCACCTTGCCGCCCAGGACTACCTGGCGCGGCTGCAAGCGTCTGGTCTTAACTTTCCACAGCTTGGTGACCCCTACGCGGCGCTGTCAGCTCTCTCCGGCTCAAGCATGAAGCAACCGAAACAACCGAAACAGCCAAGTCGAAATGAGAGATCCGGCCGCAGCAGTGTATCCAGTATGCCACCAAAAGACAAGAGTCCTTCAACGAGCACTAACTCTCAACACAGCATGGCTGACTGGGCATCAACATACGGGTTCCCAAAGACCTCGTCACCATCGACAATGGCGTCACAGTCTCTGTCGAGCCTGGCTTCCCTCAACAACCTGGCACAGCAGCCGCATCATTCCAAACCAGTCTCCAAGCAGTCACATCAGCCTCAACCTCCCAGAAAGTCATCATCAGGCAAGGAGAAGGAGCGCGACATGTCGGTGCTCCGCAGTGAGCTGATGCTGGCTCAGGCGGCGGCCCAGGGAGCCTACCACGCCGCTGTCGCAGCCGCCGCTAAGGGAAAGAACCTGCCAATGTATCCATTCAGTATGGGATCGGAGAAGGACCGTCGAGGAGGCATTGACTCCTTAACTGGTCTTCCCCATAACCTGTTGAGTGATCCGGCCGCAGTATTGGGAGGAGTTCGACTTCCACCAGatacagaaataattaaatacacctCTTCATTGACTGGTCCAAAGGTTCCAACCAGTTCCACGAACCGCGGCAGAAAGAAGACGATATCATTGGACCCGCCACACGTCTCCCTCCATCCCTCGAGCGAGCTGCCCAGCAAGAGACAGAAACTGGATGAGTACGGCAACTCTCGGTCGTCGGTGGAGGTGATACGGCTGCCGAACAAACCGGACCGAGGCAGCTCGATATCGGGCACGCCGCCACCCAACTTGTCCGATTACGCAGGTATATCGCGTGAGTTACTACAAACTATCGCAAGCCAGAGTGGAGTCAGCTTGGCAGCCCTTGAGAAACAACTGGCCGGTACGAATGCTGCAGATTCCGGTTTGAATCTAAGTACAAAGTCCAACGCCAGTTCGGAGGAAATACCCTTGGACCTGGGCTCGAAGCCAGATGACGATGCGCCACTCAACCTCTCGCTCAAACCCACCCCAGCGAACACACAAGCATCGGACGCATTGTCTCGTCTAACGTCACTTAGCAGCTCCCTCAACGCATCAAACGATAGAATATCTCGTCGTAAGCCCGGGGCGAAACCTCGGCGAGTGGCGCCTGAGTTGGTACCGCAAGGGGACATCGCCCGCCCAAGATCCAGTGGCAGTGAGGACAGTGAATCTGTGTCTCAATGGCCGTCCCGCGAAGGAAGACCTCGGAACCTAGGTAGAGGTGTGAGCAAACCCAAGAAGAATACCGTCGCGTCTTTGCTGGCACAAAGCAGAGCCTTAGGCCTTCGCCCCGCGTTAGCACATCAGCTTCTAGGCGAAACTGACTTGGAGAAACTACGGGCGCTGGTCGGAGAAGGCGGCAGTACGGACTCGGAGTGTCGCTCCGACAGTCACTCGGACTCGGACGCGAGTGACGCGGGCGTGGCCGCGGGGGGAACACCGGCCGCGGGCCCTCAGCTGCGTCTGCCGCTGGCACTGGGATGGAAGCGCGTGACGGTGATCAAGGGTCTGTCCCGCAACTGTCACATCAAAGGTGACGTCAGCTACGGCCCGCCGGCCCCTCACGAACACGTCACCATCACGTCACACAACCAGCTTGTCAATTTCCTGGAGTCAAACCCGTGTCCCCCGCTGAGTGTGGACAACTTTAGCTTTAATTCGCGCTGCGTGCTCGGCGAGTATAGCCAGCCCGGGTCGGACGTGGACCCTGTACTGCTCTCCGAGACAGACGTATCCAAGAGGTTGGAAGAAGCAAAGGCGTTGGCAGCTTTGGCAGGTCCTCGCTCCACGCCGCCTCTGGAGCGTAGAATAGAACTGGCGAGAAGACAGCAGGCTGCCAGAGACGCGAGAAGAGACGCCAGTGCTAGGAATAGAGATCAGGTGCGCTTAGTCCGGGAGCTGGAGAGATCGGAGAAGGCAGAGTATGTGAAACGCGAGAAGGAAGTACGTAGCCAACAGATATTAGAGCACATCAACAGAAATAGAAGCCAGTTGACTATTGAGGCTGTGCCTGTCCGGAACGAATGGAAGGTTCCAGAGGCCTTGACGAAGCCGAAAGACAGAACGATGCCGCAGATAAGCCTATCGCTCATCCCAGTGAGTGGCAAAGACGCGCCAATCAAAATGCTCAACTACGAACAAGGCACTTGGACACAAGAATACAACGCGCTAGATAAAATGAAAGACTTCGCCGAAAAAGCCGCTTTCGATTTGCCAAAAGCAAAAGCAGACAAGAATTATGACTTTTCGCTGACAAAAGCGGCGGAGAAGGCACAAAAGATACCGGAAGGCGAAAACAACTTGGAGAAACTAATCGAATCGTATTCGAGGATATCGGAGTTCATAAACGGCTGCGATTGGTCGAAATTGGTGAACGAAAAGAAAGTCGATGACGCTAAAGCTCTAGAACAGAAATATTTGGATGCTAAAAACGAATTTAtgacgcaaaatctaatgttaatgccaaaagataataaaaaatctgtTCTGAGGGAAGTGATAGATCTGAGCACTGAAGATGAGAATATTCTGTCGGAGATTAATAGAAAGATTTCGCAAGGCATGCTCCGTATTGGAAAAGATGGAGCTTTGTCCATCACTGTGCAGACGGTCGGGGATTTGAGTCCGGCTAAACGGAAAAAGCAAGAGGAGGTTGATAAGCAGAAGAATGAGGACCACGCGAAGAGGCAACAGGAGAGAGAAATTAAGAGACACCAGGCGATGCTGTTAAAAGAGCAGCAAAAGTATATAACGGAGGAACGTGAAAGGAGGCGACAACACACGACATTTATCAGACAATTAGATTCTAGAAGGCGCTGGGAAGAAAGAGAGAGAAGGAAGCACCAGAACCTTCTAGATCGATTGCTCGTTAAAGAGAAGAAGCTGCAACAGAGAAGAAAAGAGATGGAGCTATTGGCTGAGTTAAGGAGACCTCAAGAGGACTCGACTCTCTCGGACCAGAAGCCTCTCCCGACCCTGGAGAGGATCCCGGGCCTCAAGCTAGCTGGACAGGCCTTCGCTGATCTGCTGCAGACGTTTGAATTCTTGCATAACTTCGGCAATTCTCTTGGCTTtgtTGTGGATAGCTTGCCATCCCTCGACACGCTGCAGCAGGGATTACTGCCGGATTACAACAACGAGGCTGAAGATGAACTGGTCCTTCTCACTATCAGGCTGCTAGAAATCGCTTTAGAGGACCCAGGCATTCCACATCCAGGGAGACACACCACTCTACTGGGGCAAGCTATTCGAATTGGAGACATAACTCCGGACAACCTCAGTGAGGTTCTGAGGATATATCTGTATGCGAACGCGACCGGACAGGTCAAAGCCTTGACTGGACTTACGGTGGAGAGAGAAAGGGAGAGGAGAGTGGCAGATCACCACCAGAGCGACGCGGAGATGCAGCAGAGTTGCATGAGCAGTAAAAACGCACCCTATTATCAACACTTACACAGCAACGCCATCTATAAACTATCAGaaacGCTTCGGGATAAGCCTTTCGTATCGTTGAATCCGACGAGCAAGGCGCGTATTCTGGCCACCTTATGTGACGAGTTGCTGCAAAACAAGAGTGTTCTGCGGCAGATCGACGCGTCCCTCGACCACCTCAATCATCTGCGGAAAGAGAAATACCTCATGGATGCCAAATTTAGGAAATTGCGGGTGCTGTACACGCGGAAGACGAGGTCAGAGCACAGCGAGAAACAGCAGGCGCTAGCATTGGAGAGGATGCAGCGGTTGGTGGAAGAGAGTGTGGTCACCCGGAGTCCTCTGCACGAAAGCTCAGATAAATCACAAACGCCGAAGAAAGAGTCGTCACCGGAAAAGCCGAATACTCCGTCACCATACAAGGACTCGGAAGACCAGAGTGACAAGGAACTATCGCCTTTGAAGGACCTTTCGAACAGTATGAAGAGTAAGGAGATGCTCAACAACAATAAGGATGAATGTCCTGTTGAGGGGAAAGATAAGGACAGTGTTATGGGTGATAATGATGGTAACTTCAGTGATTTGGAAAGCGAAGGGACGCAACCTGAGGAGGATGAAGACAAGAATTTATCGTCGGAAGAGGTTGGTCGGAAGGTGGAACGGTTCAGCCGACAGTGTGAGCAGCACTCGCTACAACTAGCTGCGGCTTCGACATCATTACGAGCCGCTTGCAGCTTACAAGACAGGTATTGGCGGCGCTACTGGTCGCTGGGTAAAGCCGGTGGTATCTGGGTTGAAGCCATGGAGTCTGCTCAACCGGAGATACTCAGCTATCACGCCAGACTAGAAGATATGAAACTCAACGCGGGAGTCAAGCAGGAAGTTAAAGAAGAAATAGAAGAACTAAAAGTTAAAATGGAGGACGTAGACTCGACACGTGTGGACGCCGAGGCGGACGCGCTCGAACTGCGGAGCATCAAGAATGAATTGAACCTAAGCGACAGAACGCAGATAATCAAATATGAACCTAATAACAGCGCGTGTAAGGTTGAAGGCTCCATTAAAATGGAAGAGAAATATATTCAGCACAAACAGAACAACGAAGAATGCGACATGCTTGATATAGAAGACTCAATCCCCACGGCTTTCTTAGTCCAGAAACCTCACAAACCGGTCCCGGCTAATGAGGAAGAACCGAAAGAAATGAAAACTGAACCCGTAGAAGAACAAGAAGACCCGAAAGACAACCTCGTGAATAACCTCGAGGAACTACGGAAAATGGCCGAAGCTGTCTCATCACAGTTAGTCGCGGCGAAGAAGGCGGAAGAACAGAAAGATGTCAAACCAAAAACTGAGGAGATGGACACAGAAGACGCTCATGTACATCTATACACGAAGATGCTTGACGGGAAATGGTTTTCAATTCTGCGACACGAGATCGGCTTGACGAGTATAAACGAAAATGAGGATGTTCCAAAGTACTGTGATAATGATAAAACATGCGCGGAAATTGTCCTCAGTCAAGGGCATAGATGGGATGTGTCCAATAACTTACATTTATTAAACGATCCCAGTTTGTTTACCTTGAACAGCATGGTGACTTCGGTTCAGGTGCCCAATAACAACATTTACCCGGACAGCAGTTTGACTATGTCGGGTTTGGATCAAGATATGATCGATAATGTCAGCCATGAAACTGAATTTGAGGTTGAAAAGGAAAAAGATCAGGAAAACGATCTAGAGAAAGAACTACAAGCTGATTCAAAGGCCGACTTGTCCGCACAAAAGGCCAAAGGACTCAACAGCCTGGGTCTGCTTAACTTTAACGCTCTATCAACTTACGTCACCTGTGACTCCCCTCCACCAATCGCAATGTCGCTGGAGGAATTAGACCAATTGGATTATTGTAAGGTGCATGGTTTGCCAAAGAAAATCGAAGGAAATTATGTACCTAAAGACCTTAGgCATGGCTGGTGGCGGATCACTGACCCGGAACAAGTGCCGGCGTTGCTTAGCGCGTTACACTCTAGGGGAGTGAGGGAGAGGGAGCTATACGCGTCCCTGATGAGTCATCTGCCCACCTACAACGGAGCGCTATACGTAGACAAGGGTGACACAGGTCGTACGCAGCTCACGGTGACTGCGGCCGACGAAGAGCTCTGTCCGGCCGTCTACCCGCACCCGGACGTGCCTGGCTCGTTCAGTGCGGAGGCGGCGCGGCGCGTGGACTTGCGGCTCGCTGCTATGgTAGACGCTTTAGAAGAGCGCGTCAGTGCCGCCTCGATGCAAGTCAAAGGTTGGCGGCCGAGTCACTCCCCCCCTCCCCCGGGTGCGAGCGGCGCGGATATAGTCGAGAGAGCGAGACAGAAACTAGCGCAACTTGAAGCACACGTAGAGAGGAGATATCTAAAACCGCCTCTGGTACAAAGGTACGCTAGTACGAACGAGGCAAACCTAGGCGCAATGCTTCAGGGTGAACACGGGGCTTCGTCTGGTAACTCGCCGCAGAACTCTGACAGTGGAGAGGGAAGAGAAAGCAAGGGCATCGCTCGCGGTCTGTCAACTTGGCGGGAAGCGGTGTCGCGATGTAACACGGCCGCGCAACTCGCCATGTTACTTCGCGCCCTGGAGACGCACATCGCGTGGGACAAGAGCTGTATGAAAGCGAACTGCCAATTCTGTTTGTGCGGTGACAATGAGGACCAACTGCTGCTATGCGACGGTTGCGACAAGGGTTACCACACGTACTGCTTCAAGCCCAGGATGGAGAAGATACCGGAAGGAGACTGGTGA
Protein Sequence: MDKESGDGGDSTAKPPPDPLLDPSSLFGAYWGRDGGASSAQAQAQAQAALFGFGSRYPAPSTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPQLGDPYAALSALSGSSMKQPKQPKQPSRNERSGRSSVSSMPPKDKSPSTSTNSQHSMADWASTYGFPKTSSPSTMASQSLSSLASLNNLAQQPHHSKPVSKQSHQPQPPRKSSSGKEKERDMSVLRSELMLAQAAAQGAYHAAVAAAAKGKNLPMYPFSMGSEKDRRGGIDSLTGLPHNLLSDPAAVLGGVRLPPDTEIIKYTSSLTGPKVPTSSTNRGRKKTISLDPPHVSLHPSSELPSKRQKLDEYGNSRSSVEVIRLPNKPDRGSSISGTPPPNLSDYAGISRELLQTIASQSGVSLAALEKQLAGTNAADSGLNLSTKSNASSEEIPLDLGSKPDDDAPLNLSLKPTPANTQASDALSRLTSLSSSLNASNDRISRRKPGAKPRRVAPELVPQGDIARPRSSGSEDSESVSQWPSREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLGETDLEKLRALVGEGGSTDSECRSDSHSDSDASDAGVAAGGTPAAGPQLRLPLALGWKRVTVIKGLSRNCHIKGDVSYGPPAPHEHVTITSHNQLVNFLESNPCPPLSVDNFSFNSRCVLGEYSQPGSDVDPVLLSETDVSKRLEEAKALAALAGPRSTPPLERRIELARRQQAARDARRDASARNRDQVRLVRELERSEKAEYVKREKEVRSQQILEHINRNRSQLTIEAVPVRNEWKVPEALTKPKDRTMPQISLSLIPVSGKDAPIKMLNYEQGTWTQEYNALDKMKDFAEKAAFDLPKAKADKNYDFSLTKAAEKAQKIPEGENNLEKLIESYSRISEFINGCDWSKLVNEKKVDDAKALEQKYLDAKNEFMTQNLMLMPKDNKKSVLREVIDLSTEDENILSEINRKISQGMLRIGKDGALSITVQTVGDLSPAKRKKQEEVDKQKNEDHAKRQQEREIKRHQAMLLKEQQKYITEERERRRQHTTFIRQLDSRRRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLAELRRPQEDSTLSDQKPLPTLERIPGLKLAGQAFADLLQTFEFLHNFGNSLGFVVDSLPSLDTLQQGLLPDYNNEAEDELVLLTIRLLEIALEDPGIPHPGRHTTLLGQAIRIGDITPDNLSEVLRIYLYANATGQVKALTGLTVERERERRVADHHQSDAEMQQSCMSSKNAPYYQHLHSNAIYKLSETLRDKPFVSLNPTSKARILATLCDELLQNKSVLRQIDASLDHLNHLRKEKYLMDAKFRKLRVLYTRKTRSEHSEKQQALALERMQRLVEESVVTRSPLHESSDKSQTPKKESSPEKPNTPSPYKDSEDQSDKELSPLKDLSNSMKSKEMLNNNKDECPVEGKDKDSVMGDNDGNFSDLESEGTQPEEDEDKNLSSEEVGRKVERFSRQCEQHSLQLAAASTSLRAACSLQDRYWRRYWSLGKAGGIWVEAMESAQPEILSYHARLEDMKLNAGVKQEVKEEIEELKVKMEDVDSTRVDAEADALELRSIKNELNLSDRTQIIKYEPNNSACKVEGSIKMEEKYIQHKQNNEECDMLDIEDSIPTAFLVQKPHKPVPANEEEPKEMKTEPVEEQEDPKDNLVNNLEELRKMAEAVSSQLVAAKKAEEQKDVKPKTEEMDTEDAHVHLYTKMLDGKWFSILRHEIGLTSINENEDVPKYCDNDKTCAEIVLSQGHRWDVSNNLHLLNDPSLFTLNSMVTSVQVPNNNIYPDSSLTMSGLDQDMIDNVSHETEFEVEKEKDQENDLEKELQADSKADLSAQKAKGLNSLGLLNFNALSTYVTCDSPPPIAMSLEELDQLDYCKVHGLPKKIEGNYVPKDLRHGWWRITDPEQVPALLSALHSRGVRERELYASLMSHLPTYNGALYVDKGDTGRTQLTVTAADEELCPAVYPHPDVPGSFSAEAARRVDLRLAAMVDALEERVSAASMQVKGWRPSHSPPPPGASGADIVERARQKLAQLEAHVERRYLKPPLVQRYASTNEANLGAMLQGEHGASSGNSPQNSDSGEGRESKGIARGLSTWREAVSRCNTAAQLAMLLRALETHIAWDKSCMKANCQFCLCGDNEDQLLLCDGCDKGYHTYCFKPRMEKIPEGDW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00876192;
90% Identity: iTF_00876192; iTF_00875328;
80% Identity: -