Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.019 75 4.0 0.1 20 44 184 208 176 212 0.84

2 6 0.0076 30 5.2 0.1 21 45 213 237 209 242 0.82

3 6 0.0026 10 6.7 0.2 22 43 242 263 237 268 0.89

4 6 0.017 69 4.1 0.0 21 44 269 292 264 296 0.88

5 6 0.00033 1.3 9.6 0.0 21 45 297 321 292 328 0.86

6 6 0.033 1.3e+02 3.2 0.0 21 43 325 347 321 353 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.019	75	4.0	0.1	20	44	184	208	176	212	0.84
2	6	0.0076	30	5.2	0.1	21	45	213	237	209	242	0.82
3	6	0.0026	10	6.7	0.2	22	43	242	263	237	268	0.89
4	6	0.017	69	4.1	0.0	21	44	269	292	264	296	0.88
5	6	0.00033	1.3	9.6	0.0	21	45	297	321	292	328	0.86
6	6	0.033	1.3e+02	3.2	0.0	21	43	325	347	321	353	0.86

Coding Sequence: ATGGAATTAAATAAATTGTGCCGCACTTGTTTGTCAGCGTCTGAAGACATGCAATCATTATATGAGACGTGTGCAACTTCCACGCAAATTTGTTGTGCTGAAATCTTATCAACTTTCACACCATTAATTTGTTGTAAAGACGATGGCCTTCCCACAATGATCTGCCACAATTGCATTAGAGAAATAAACCGGTTTCATTCATTCCGATTGAAATGTCTTCAATCTGATGGAGTTTTACGGAAACACGTAGAAGAAGTTACTAAAGTTGCGGGAACAAATATTACTGTGACGAATGAACAAACAGAATCACGCATACAAGATTCGATTAAGCTTGAAGAAAATATGGATGAGAATAGTCGTATTTTTGAAGAGGTGTTGATAAAAAGTGAATTTCCTGTAAGTCTAGCAAAATCATTAAAAGACCCATTATCAATTGCTGAAATGCAAACAGACGTGAATCAAGTATTAGACATAGTAAAGCATGAAGTCAATGTTGATATTAAGATTGAAGAGGACCTTGAAGTAAATAATGCACCAGTGAATGAACAAGAAAAGAagaagccattttcgtgtttcatgtgtaatcattcatataaacaaaagcaaaatttaacgatacatatgcggacgcatacaggagagaagccttatacctgtacagtatgcgacagttcattccaatcaagaaaacaattaacgtctcacatgcggatacatacagaagataaaccatataagtgtacaatttgcaacagcgcatttagacacttgcaaaatttaaagtcgcacaagcggacgcatactggagagaaaccttattcgtgtacactttgtgatagttcgtttacacaacccattaatttaacaatgcatatacggacgcatacaggagagaaaccttattcatgtacagtttgtgacagttcgtttacacagtcatataatttaacaatgcatatgcgaacgcatgcaggagagaaaccttattcctgtacagtatgtgacagttcgttcaaatctaaacgaagtttaacgatgcataagcgaaaacataccgaagagaattcatag
Protein Sequence: MELNKLCRTCLSASEDMQSLYETCATSTQICCAEILSTFTPLICCKDDGLPTMICHNCIREINRFHSFRLKCLQSDGVLRKHVEEVTKVAGTNITVTNEQTESRIQDSIKLEENMDENSRIFEEVLIKSEFPVSLAKSLKDPLSIAEMQTDVNQVLDIVKHEVNVDIKIEEDLEVNNAPVNEQEKKKPFSCFMCNHSYKQKQNLTIHMRTHTGEKPYTCTVCDSSFQSRKQLTSHMRIHTEDKPYKCTICNSAFRHLQNLKSHKRTHTGEKPYSCTLCDSSFTQPINLTMHIRTHTGEKPYSCTVCDSSFTQSYNLTMHMRTHAGEKPYSCTVCDSSFKSKRSLTMHKRKHTEENS

Sequence clustering based on sequence similarity using MMseqs2