Lspi013651.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Leistus spinibarbis
Gene Symbol
Hr39
Assembly
GCA_933228875.1
Location
CAKOGB010000328.1:2156-7938[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.12 1.4e+03 -1.2 5.3 45 113 201 273 100 326 0.56
2 4 1.5e-08 0.00018 21.5 0.0 1 23 415 437 415 441 0.91
3 4 0.00026 3.1 7.5 1.9 68 147 457 537 435 553 0.64
4 4 3.2e-73 3.8e-69 234.5 0.1 206 408 554 751 547 751 0.98

Sequence Information

Coding Sequence
ATGACTTCAGAGATGCGTTCTCCAAACGTATCAGTAACCGCAATCAATGTCGATCAGCGAACCGACTATTTCAACCCAAATGCAGCTAGCATCGCGGCAGCTATAACGGAATCGGTAGTCCGGGAACCAGCGGACAGCGGATCCGATGCAGAGGTCGCTCAAATTCATTTTCAGAGTAGTGTAAATATGCGCACGAAAATAATAGATGATCTCGTCGATATTCCACGACCCATGTCCTGGGAAGGTGAACTGTCTGATGGCGGAGGCGATATGTGTGTCGATGAGGATAGCGTATCGAATTGCCCCGAAAATTTATGCGTTACGTACCAAAACAAAGGGAATACTGCGGCGACGGCGACTGCGACATCGACGGCGACATCGACAGCGACTTCTCTACCGGAACTGAAAGACAGCCCGCTGCTTCGACTGAAACAACCTGCAGTCGGCAACTATTCCTTGCATTCAACGCCTAGCAACTCTCCGTTGATGGGACAGCGGCATATAGGTGCACAAGCGCATATCTTGGGCCATAAAGGATTGAATGTACCACCTACACCGAGTCCAGACTCTGCTATTCATTCGGCATACAGTGTATTTAGTTCACCGAGTCAATCACCTTTAACCCAAAGACATGTTACGCTCACACCATCCTTGTCACGAAACAATAGCGATGCGTCGCATTCGAGTTGTTGCAGTTATTCCAGTGTTTCTGTATCTGTATCACCTACACAACAATTCTCACCCACTCATTCGCCAATACAGGGTCGCCATATCCATCAAATACATGGCAGCCCGTTGCACCACAATGTGATTTATAGAAACATCCAGGAAACGGTCGAACACAGTGCCATATATGTTCGGCAACATGAGACAGCGTCAGCGACAGCGACCGTATCTCAGATCGGCGACACTGATCTGTTGACGGATCAGGATCAAGATTCTGCTACAGGTTTAGATGACGAGGATAAGACTGGAATTGTGCACGTATTACCTTCAGGACCTGGTATCTCACGCCAACAATTAATAAACAGTCCATGTCCAATATGCGGTGACAAAATTTCCGGATTTCACTATGGCATCTTTAGTTGTGAATCGTGCAAAGGTTTCTTCAAACGTACTGTACAAAATCGAAAAAATTATGTATGTTTACGAGGTGCTACATGTCCTGTAACCATTTCAACGCGGAAAAAATGCCCAGCGTGTCGATTCGATAAATGTCTACAATGTGGCATGAAACTTGAAGCTATTCGAGAGGATAGAACACGAGGTGGTCGATCAACGTACCAATGTTCGTACACGTTGCCTGCTTCATTGGTAGCGCATCCTGATTTGCGCGTAAGTAATTCAGATCTCCGTCATAGTATCGGTGGGGACCAACACCATACAGTGGTTAAACTAGAGCCAGGAGATCAGTCTGCACTGCCTTGTACCTCTTCCACAAAACGAACAAGCAGTTCATCATCAAGGCATAATGTACCAGCATTATTACAAGAAATTATGGATGTAGAGCACTTATGGCACTATAGCGAGGTTGAGCTATCAAAACTCCATCAAACTAGTACTTCTACACCCAACAAAACATCTTCCAACAGCGCTTCAATAAGTTTATCATCGCATCCGCTTTTAGCAGGCACTGGTCTGGCTGGGACAGCCGATACAAATCCAGATTTCGTCGCGAACCTGTGCAATATCGCTGATCATCGTTTGTATAAAATTGTGAAATGGTGCAAAAGTTTGCCACTCTTCAAGAATATATCAATTGATGATCAAATATGTTTACTCATCAATTCCTGGTGTGAATTGTTATTGTTTTCGTGTTGTTTTCGATCTATGGTTAGTCCGGGTGAAATCAGAgtttcgttagggaagagtataaacttggtacaagcCCGCGAAATGGGCCTTCAAGCATGCATAGAACGTATGCTGAATTTTACCGACCATTTAAGAAGATTACGAGTCGATCGTTATGAATATGTTGCCATGAAAGTGATTGTACTTCTTACTTCCGATACCTCCGAGCTTCGTGAAGCTGAAAAGGTGCGAGCCTCACAAGAAAAAGCCCTACAAGCATTACAAGGTTACACCCTGATGCACTATCCAGATATACCAGCGAAATTCGGCGAATTACTTTTACGAATACCCGAACTACAACGAACTTGTCAGGTGGGAAAAGAAATGCTAACGATCAAATCAAAAGATGGCGAAGGACCCAGTTTTAATCTGCTCATGGAATTACTGCGAGGGGACCATTAA
Protein Sequence
MTSEMRSPNVSVTAINVDQRTDYFNPNAASIAAAITESVVREPADSGSDAEVAQIHFQSSVNMRTKIIDDLVDIPRPMSWEGELSDGGGDMCVDEDSVSNCPENLCVTYQNKGNTAATATATSTATSTATSLPELKDSPLLRLKQPAVGNYSLHSTPSNSPLMGQRHIGAQAHILGHKGLNVPPTPSPDSAIHSAYSVFSSPSQSPLTQRHVTLTPSLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGRHIHQIHGSPLHHNVIYRNIQETVEHSAIYVRQHETASATATVSQIGDTDLLTDQDQDSATGLDDEDKTGIVHVLPSGPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGATCPVTISTRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYTLPASLVAHPDLRVSNSDLRHSIGGDQHHTVVKLEPGDQSALPCTSSTKRTSSSSSRHNVPALLQEIMDVEHLWHYSEVELSKLHQTSTSTPNKTSSNSASISLSSHPLLAGTGLAGTADTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMVSPGEIRVSLGKSINLVQAREMGLQACIERMLNFTDHLRRLRVDRYEYVAMKVIVLLTSDTSELREAEKVRASQEKALQALQGYTLMHYPDIPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01040206;
90% Identity
iTF_00873148;
80% Identity
iTF_00873148;