Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1.7 1.5e+03 -1.0 0.1 24 35 91 102 73 115 0.61

2 5 0.0018 1.6 8.5 0.3 21 44 116 139 108 143 0.90

3 5 3.6e-07 0.00031 20.3 0.3 21 52 144 175 141 176 0.88

4 5 0.17 1.4e+02 2.2 0.2 21 34 172 185 168 198 0.77

5 5 0.0012 1.1 9.0 0.0 21 44 200 223 191 227 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1.7	1.5e+03	-1.0	0.1	24	35	91	102	73	115	0.61
2	5	0.0018	1.6	8.5	0.3	21	44	116	139	108	143	0.90
3	5	3.6e-07	0.00031	20.3	0.3	21	52	144	175	141	176	0.88
4	5	0.17	1.4e+02	2.2	0.2	21	34	172	185	168	198	0.77
5	5	0.0012	1.1	9.0	0.0	21	44	200	223	191	227	0.85

Coding Sequence: aTGGCAGTTCCTTTATCAGAATATTGCGAAGTAAAATGTCCACGCTCGGATCTTCGGGTGGACACTTTTAGAGTTTCGGTTGATTCACGTGGATCGTCGATGAGACGAAGAATGAAATCAACGAAGAATGAAAAGCCATTGCATCAAGATACCAGAGAACATCAGGAATATTTTAATCCTTTGCAACCTGAGTCTGCATTGAACAGCCAAACGAAGTGCAGTCAACCTGATGCGTTACGAAAACACACGGAATCTCACACAGACCCGAAATCAAATACTTGTGGcctttgtaaaaaatcatttcaaagaaGAATTGATTTTGAGAGACACAACCTAACTCATACAGGAGAAAATCCTTTTTCATGTGCCACATGTGAAGCATCATTTAGTCGAAGAAGTAACCTAAAAAGACATATTCGAACTCACACCGGCGAAAAACCTTTTACATGTGCCACCTGTCAAGCATCATTTACTCAAAATAGAACTCTTAGAAGACACATTCAAATTCACAGTGAAGAAAAACCTTTTACATGTGCCACCTGTGAAGCGTCGTTTAGTCTAAAAAGTTATCTAAAATTGCACGAGCGAACTCATTCAGGAGATAAACCATTTGTCTGTGACGTCTGTAAATTATCATTTAGTCGTAGTGGTAACTTAAAAAGACACATgggaactcacactggagaaaaaacGTTATTGGGTAGTTGTCCTTCATCCTTCAGGGATGCAGGAAATCTAATGGTTCTCAAGCGTTTTCACAct
Protein Sequence: MAVPLSEYCEVKCPRSDLRVDTFRVSVDSRGSSMRRRMKSTKNEKPLHQDTREHQEYFNPLQPESALNSQTKCSQPDALRKHTESHTDPKSNTCGLCKKSFQRRIDFERHNLTHTGENPFSCATCEASFSRRSNLKRHIRTHTGEKPFTCATCQASFTQNRTLRRHIQIHSEEKPFTCATCEASFSLKSYLKLHERTHSGDKPFVCDVCKLSFSRSGNLKRHMGTHTGEKTLLGSCPSSFRDAGNLMVLKRFHT

Sequence clustering based on sequence similarity using MMseqs2