Lko_23427-RA
Basic Information
- Insect
- Laupala kohalensis
- Gene Symbol
- Lztr1
- Assembly
- GCA_002313205.1
- Location
- NNCF01133003.1:360391-371811[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3.2e-11 3.4e-09 36.4 0.0 4 108 389 522 386 524 0.87 2 4 0.5 53 3.6 0.2 67 108 514 554 512 556 0.87 3 4 2e-19 2.1e-17 62.9 0.0 3 94 609 700 607 715 0.87 4 4 0.79 84 3.0 0.1 75 101 715 741 705 749 0.82
Sequence Information
- Coding Sequence
- ATGTCTCGAAAAGCTGTTCAATTACCTGAATCTGCTGAAGGATTGATGCTTGATTTTGGACCATTTGAAACTGTCCATCGATGGGCTCGTATGCCAGAATGTGATGAATTTGTTGGTGCTAgttttattgatctgttcaataaatctttttgttttgattcttCCATCAGACGAAGTAAGCATACAGTGGTGGCTTATCTTGACGCAATTTATGTATTTGGTGGAGATAATAGCAAGAGTATGTTGAATGATTTGTTGAGATTtgatgtgaaagaaaaatcatgGGGTCGAGCTTTCTCAACGGGAACACCACCTGCTCCTCGCTATCATCATTCAGCTGTTGTTCATGAAAGTTCCATGTTTGTGTTTGGAGGATATACAGGAGACATTCATTCCAATTccaatttgacaaataaaaacgACCTCTTTGAATATCGTTTTGGAAGTGGGCAGTGGATCGAATGGAAGTTTTTTGGAAAAACACCAGTTCCTCGGTCAGCACATGGAGCTGCAGTGTATGATGGTAAACTCTGGATATTTGCTGGCTATGATGGAAATGCACGCCTTAATGATATGTGGACTATTTCATTGACTggaGACAGCAAAGCATGGGAAGAGGTGCATCAGCTGGGTGACTGTCCTCCCACGTGCTGCAATTTCCCGGTGGCGGTGGCTCGAGAGTGCATGTTTGTGTTCAGTGGACAAAGTGGGGCCAAGATCACCAACAACCTCTTCCAGTTTCATTTCAAAGATCGATGGTATGATGTTAATGTGCTTCTAATGGTTCCTTCTCCTACTTTGTACAGCTGGACCAGAATTTCAACAGAGCACATTCTTCGAGGAGCTCCTCCTCCACCTGCTCGACGTTACGGCCATACAATGGTTGCATTTGATAGACACTTGTACGTGTTTGGAGGAGTTGCAGACTCTACGCTCCCCAACGATCTCCATTGTTACGATCTGGACCAACAGACGTGGAGCGTGATTCCCCCTGCTCCCGATTCCTACGTTCCTTCAGGGCGCCTCTTCCACGCTGCTGCTGTCGTTGGAGAAGCAATGTTTGTGTTTGGAGGGACTGTGGACAACAACTTGCGATCAGGGGAGATGTATCGATTTCAGttCTCCTGTTATCCCAAATGTACTCTTCACGAAGACTTTGGCCGAATCTTAGACAGAAAACTTTTCTGTGATGTCCAATTTGTCGTCGGCCTAGAAGAAACAAGAATTGAGGCTCATATTCCAATAATTGCTGCGAGGTCCCAGTGGTTGCGCACGCGAATCAGACAAGCAATCGAGGCACGAGACAAGCATCTCGAGAAGTTATTTGGTACAACTCAAGTTTCATTCAAGGGAGTTCCTCTTCCTGAAGTGAAGTTGACCGATGCTGTTCCGGAAGCTTTTGAAATGGTTCTCAACTATATATACACTGATCGCATTGATCCCACAAAGAAAATTGAAGATCCAACAAGCAATCGTATTGTACTTCTTATGATGGACGTCTACAGGTTAGCTGTTCAGTTTGACATGCGTCGGTTAGAACTCCTGTGTGTGCAGTATTTAGAGGCAACCGTTTGCTGTCGTAACGTGTTAGAAGCTCTCACAAACGCTGCAAGGCTCAAGTTATACTTCATCAAGGAATTATGCCTCAAATTTATTGTGAAGGATACCAATTATACCACAATTGTGATGAGTCGAGAGTTTGAGACGCTCGCTCAACCGCTGATGGTCGAAATCATCCGACTGAGACAAGTTCCTAGAGCTCGACCTTTGCCAGAACCCCACTTTGATGGAAACGttGGCACCACTCTTGAGCAAGATATGGAGACGTTTTTGAAAGGAGGAGAATTATGTGATATAATGCTATTGTTGGAAGGAGAGACAATTCCAGCGCACAAGTCAATTTTAGCTGCTCGTTGTTCATATTTTGAAGCTCTGTTTCGTTCCTTTATGCCCGAAGACAAAGTTGTTCATattcaGATTGGAGACGTTGTTCCATCACGCCAAAGTTTTGATTCTTTGTTACGGTACATATATTATGCCGATGTGGCTATGCCCCCTGAAGAttccttgtatttattttcagctCCATTTTTCTATGGATTTACAAACAACCGTCTTCAAGCTTTCTGTAAGCATAATCTAGAAATGAACATCACTTTTGAGAATGCCGTTCAAATTTTGGAAGCTGCTGATCGCATGCAAGCTCACGATATGAAGAAGTATGCTTTGTCCATCATCGTGCATCACTTTTCAAAGGTGGCCAGACTGCCTCGCACGAGGACTCTGACCAAGGAGCTGTTGCTGGATATCATCGACGCTCTCGCCGACGATCTCAGTGAGCACCGACCTACCCAAGACGTAACATGTGTTTCTCTCACTTCTGATTGTTGA
- Protein Sequence
- MSRKAVQLPESAEGLMLDFGPFETVHRWARMPECDEFVGASFIDLFNKSFCFDSSIRRSKHTVVAYLDAIYVFGGDNSKSMLNDLLRFDVKEKSWGRAFSTGTPPAPRYHHSAVVHESSMFVFGGYTGDIHSNSNLTNKNDLFEYRFGSGQWIEWKFFGKTPVPRSAHGAAVYDGKLWIFAGYDGNARLNDMWTISLTGDSKAWEEVHQLGDCPPTCCNFPVAVARECMFVFSGQSGAKITNNLFQFHFKDRWYDVNVLLMVPSPTLYSWTRISTEHILRGAPPPPARRYGHTMVAFDRHLYVFGGVADSTLPNDLHCYDLDQQTWSVIPPAPDSYVPSGRLFHAAAVVGEAMFVFGGTVDNNLRSGEMYRFQFSCYPKCTLHEDFGRILDRKLFCDVQFVVGLEETRIEAHIPIIAARSQWLRTRIRQAIEARDKHLEKLFGTTQVSFKGVPLPEVKLTDAVPEAFEMVLNYIYTDRIDPTKKIEDPTSNRIVLLMMDVYRLAVQFDMRRLELLCVQYLEATVCCRNVLEALTNAARLKLYFIKELCLKFIVKDTNYTTIVMSREFETLAQPLMVEIIRLRQVPRARPLPEPHFDGNVGTTLEQDMETFLKGGELCDIMLLLEGETIPAHKSILAARCSYFEALFRSFMPEDKVVHIQIGDVVPSRQSFDSLLRYIYYADVAMPPEDSLYLFSAPFFYGFTNNRLQAFCKHNLEMNITFENAVQILEAADRMQAHDMKKYALSIIVHHFSKVARLPRTRTLTKELLLDIIDALADDLSEHRPTQDVTCVSLTSDC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00759343;
- 90% Identity
- -
- 80% Identity
- -