Basic Information

Insect: Laupala kohalensis
Gene Symbol: Hr39
Assembly: GCA_002313205.1
Location: NNCF01126435.1:252591-264805[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.26 1.7e+03 -2.4 3.6 136 163 354 381 240 468 0.58

2 3 7.6e-09 5e-05 22.4 0.0 1 28 616 643 616 679 0.81

3 3 1.6e-54 1e-50 172.9 0.1 237 408 695 861 688 861 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.26	1.7e+03	-2.4	3.6	136	163	354	381	240	468	0.58
2	3	7.6e-09	5e-05	22.4	0.0	1	28	616	643	616	679	0.81
3	3	1.6e-54	1e-50	172.9	0.1	237	408	695	861	688	861	0.98

Sequence Information

Coding Sequence: ATGAACGATACACAAGTCGTGCCCAACAGCACCACGCTGGCTCCCGAAGGTCCGCTGTTCGGCGGCCACTCACATTCCCAGAGCCTCGCCTGCAAGGCGGCGGTCAAACCGACGACGGTGCCGGCGGCTGCGGCTTCCGTCCCGctgaccgccgccgccgccgcatcaGCTTCCCTGGCGATGGACCCGTGTGGCGGCCGATCCACTGGGGAATCTGCCACGCCGCCGGCCAAGGGGCAAGCCAGCGTTTCTGCAAAAGTGAAGTTGGGGGAAAGAGGGACAGCTGTAGTGTCGGCAGCCTCTGGCTCCGTGACTGTGATTAGTGTGCAACACGGTGGTAGCAACCCGGTGACCCAAGACTCTTCCTTGGAAGACGaaaatgcTGTTCCCCCACAGCATATTCGTCATATTCCTGGCAAAACTGACTTGCCTGTGACTGCAAATGGTAGTATTAAGTCCATGCCTtgtgaagatgaagatgaagaagaagaagatgatgatgatgatgatgatgatgtttcAGGCTCTGATGGTGAAGTTAGCAAAATAGATTTCACAGGTGTAAATCTTAGGACAAAAAAGAAGCGAGTAATTGGTGAGGAGTCTCAGGATGGCTTTGAAGAACCAGAGCGTCCAATGTCTTGGGAAGGAGAATTGTCAGATGCAGAAATGAGTATTATTACAAGTAATGTTAGCAAAGAGGTGAGAAATGATAGAATTCAAGATCATGAAGAAACATCAATGGAAGGAGTGCAGATATGTGGAGTAAATTCTGTTCATGGACATAATGAAAGTAAAcatacttttgaagaaaatatgaTTGACATCAGACATAAACAGTTACCCCATCAACCTTTAATTAGTAGTGGGGTTTCTTCACTAGGGAGTGGAAATATGACTTCGGCTGGAGTAGCTGAACTTCCATTGCTTGTTGATAAACTCCTGGGGTACGGCAATACCACTCCATCCCATAGTCCTGTTCTTCAGCAGAGACATCCTCATGCTCTTCCAACAAAGCCCTTGCCACCTTCTCAAATTGTTCCTCCTACACCATCACCAGATTCGGCAATTCATTCAGCATATTCTTACTCTTCCCCTGCACAAAGCCCTGTTACTTCACGTCATGGCAGTAGTCATGGATTACCATCATCAGGATTCAGTTCTCCTTACACACCTTCTCTCTCTCGAAATAATTCTGATGCCTCTCAGTATGGAGGGTCACAACATAGCAGCTGCTATAGTTACAGTTCCGTTTCTGTATCGCCTACACAGTTTTCACCAACCCATTCACCCATTCAGTCTCGGCATATCTATGCAGGACATTCAGGACCACCTGCTGGGTTTCCTTCCCCAGTTATGGCCCGAGGTGCTGCTCCAGAATTCACATCATCAGGCTCTGTTAGTTCCCCTCTTCATATGATGGCAGGAGGAGTGCTGTATGGAGGTGTTGCATTGCCTAGAGGCACAGTTGTTCCAGTTGATGAACAGGATGGTTCCTCAACAGATGCTAATGatgaTCGGGAAAGTAATAATAGTATTTTGGATGACAAGATGTCTTCCTTAGCAGCTGATTTAGTGCAACACAGTAATTTGGCTGCTCCACCTGGTATCTCTAGACAACAACTTATTAACAGCCCATGCCCCATTTGTGGTGACAAGATCTCAGGTTTTCACTATGGAATCTTCTCATGTGAGAGCTGTAAAGGTTTTTTTAAGAGAACTGTACAAAATAGAaagaattatgtttgtcttcGTGGATCTTCCTGTCCTGTTACAATTGCTACAAGAAAGAAATGCCCAGCTTGCCGTTTTGATAAGTGCCTGAAGATGGGCATGAAACTTGAAGCCATTAGGGAAGATCGTACACGAGGAGGCCGTAGCACTTACCAGTGTTCGTACACCTTGCCTGCCAGCTTGGTTGCCCCTTCTGGCAGCGAGGGTACTAATCACAAGCTTCTTGCTTCCTCTGGTGACCCCCAGGTCAAGCTGGAGGCTCCAGATGTGGGAGCAGTTGCTGGTAGTAGTGCTGGAAGTGGAACAGGTTACAATAATCGTCACACTGACAAAGCAGTCCCACAATTACTCCAGATTGATGATCAAATCTCTCTCTTGATCAATGCCTGGTgtgaattgttattgttctcCTGTTGTTTTCGCTCTATGTCTACTCCAGGCGAAATTCGAGTGAGTTTAGGAAAATCCATTTCCCTTGCTCAAGCTCGAGAAATGGGTCTTGGTGCTTGCATAGAGCGTATGCTGAATTTCACTGAACATTTACGTCGTTTGAGAGTAGATAAATATGAATACGTGGCTATGAAGGTCATCGTACTTCTTACATCTGATGCAAGCGATTTGAAGGAATCTGAAAAAGTGAGAGCCTCTCAAGAAAAGGCATTGCAAGCTTTACAACACTATACCTTGTCACATTATCCagaaattccttcaaaatttgGTGAACTTCTCTTAAGGATTCCTGAACTTCAGAGAACTTGTCAGGTGGGAAAAGAGATGTTATCTGTTAAGAACAAAGAGGGAGAAGGTCCCAGCTTCAACTTGCTCATGGAATTGCTGAGAGGGGACCACTGA
Protein Sequence: MNDTQVVPNSTTLAPEGPLFGGHSHSQSLACKAAVKPTTVPAAAASVPLTAAAAASASLAMDPCGGRSTGESATPPAKGQASVSAKVKLGERGTAVVSAASGSVTVISVQHGGSNPVTQDSSLEDENAVPPQHIRHIPGKTDLPVTANGSIKSMPCEDEDEEEEDDDDDDDDVSGSDGEVSKIDFTGVNLRTKKKRVIGEESQDGFEEPERPMSWEGELSDAEMSIITSNVSKEVRNDRIQDHEETSMEGVQICGVNSVHGHNESKHTFEENMIDIRHKQLPHQPLISSGVSSLGSGNMTSAGVAELPLLVDKLLGYGNTTPSHSPVLQQRHPHALPTKPLPPSQIVPPTPSPDSAIHSAYSYSSPAQSPVTSRHGSSHGLPSSGFSSPYTPSLSRNNSDASQYGGSQHSSCYSYSSVSVSPTQFSPTHSPIQSRHIYAGHSGPPAGFPSPVMARGAAPEFTSSGSVSSPLHMMAGGVLYGGVALPRGTVVPVDEQDGSSTDANDDRESNNSILDDKMSSLAADLVQHSNLAAPPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVTIATRKKCPACRFDKCLKMGMKLEAIREDRTRGGRSTYQCSYTLPASLVAPSGSEGTNHKLLASSGDPQVKLEAPDVGAVAGSSAGSGTGYNNRHTDKAVPQLLQIDDQISLLINAWCELLLFSCCFRSMSTPGEIRVSLGKSISLAQAREMGLGACIERMLNFTEHLRRLRVDKYEYVAMKVIVLLTSDASDLKESEKVRASQEKALQALQHYTLSHYPEIPSKFGELLLRIPELQRTCQVGKEMLSVKNKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00872310;
90% Identity: iTF_00872310;
80% Identity: iTF_00872310;