Basic Information

Insect: Lathronympha strigana
Gene Symbol: PLAGL2
Assembly: GCA_949128165.1
Location: OX421923.1:8618252-8619748[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00014 0.012 17.3 0.8 1 23 102 124 102 124 0.97

2 7 0.00012 0.01 17.5 1.8 1 23 130 152 130 152 0.96

3 7 4.9e-08 4.3e-06 28.1 1.9 1 23 158 180 158 180 0.97

4 7 0.012 1.1 11.2 0.6 1 23 187 211 187 211 0.94

5 7 0.00055 0.048 15.4 0.2 2 23 219 240 218 240 0.97

6 7 0.0002 0.018 16.8 1.7 1 23 254 276 254 276 0.97

7 7 4.5e-05 0.004 18.8 2.4 1 23 282 305 282 305 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00014	0.012	17.3	0.8	1	23	102	124	102	124	0.97
2	7	0.00012	0.01	17.5	1.8	1	23	130	152	130	152	0.96
3	7	4.9e-08	4.3e-06	28.1	1.9	1	23	158	180	158	180	0.97
4	7	0.012	1.1	11.2	0.6	1	23	187	211	187	211	0.94
5	7	0.00055	0.048	15.4	0.2	2	23	219	240	218	240	0.97
6	7	0.0002	0.018	16.8	1.7	1	23	254	276	254	276	0.97
7	7	4.5e-05	0.004	18.8	2.4	1	23	282	305	282	305	0.94

Sequence Information

Coding Sequence: ATGGCCAGTCCGCCTCCGAACCCTAGAGCTGGCGGGGACGACGGTGGCGGGCAGGACGCGGGTGAGGACAGCCCGCCCGCCTCGCCGAAGACGGTCctagcgccgccgccgccgcagcacgGCACCAAGCTGCACTATGTGGCTCTGGCCGCGCCCGGGCCCAGCGGTATCAAGCAGTGTTTTCGCACCGTCAAGGCGGCGCGTCGAGTGCCAACCCTGCCGCGGCGACGCGAGGAGCCTGGCGCGCCTGAGCCGCCGTCTGAGCCTCGcgagcgccgcgcgcgccgtgaTCGCTCCAAGCGCCACGTCTGCGGCACCTGCGAAAAGCGGTTCTCCAGTCCCGGCAAGCTCAGCCAACATGTCCTATCCCACACCGGTGAGCTCCCGTTTTCCTGCGATCTGTGTGACAAGCgatttaattcaaaattcaaacttGTTCGACACAATCTCATCCACAGTGAAGCCCGAGCCTTCGCATGCAATGTATGTGGTAAAACTTTCAATAGAAAAGATCACCTGACGAACCATGTCCGAGTGCACAATCCTGTCAAAAAGTTATACACCTGTGAAAGGCCAGATTGCAGGAAGTCATACACTTCCCTACTTAGTTATAGGAAGCATGCAGCACTGCACTCTGCTGAGGAAGGCAACCTGCAGTGCAAGATCTGTGATGAAGTATTCACTACTACACAAGATATAGTTTATCATCTTAAAGTCCATACAGGTAGCCGGACTGTAAAAAATGAGACTGACAAAAAATTTACATGCACCTACTGCGAGCGACGGTTCTTTACGGCGAAAGACGTGCGACGCCATCAGGTGGTCCATACGGGCCGGAGAGACTTCCTGTGCCCTCACTGTCCTCAAAAATTCGGAAGGAAAGACCATCTAGTAAGACACGTTAAAAACGCTCATCCCGAAGAGCCTTGGAGATCTGCAGCTGTTGGCACCTCAAAGGACCCCACCCCAGAAGGTATTTCATATGATGAAATTGTGATACCTGAGCCAGCATCCTACACTGAGTATGCCATAGAGAGTCCAGATTACACATGGAAATCACCCTCGCCAAAAGACTCAACCCCAGAAGGTCCAACAAGGGTACCCTCGTCCGATATAATTGTGGAGATTCAGCCagattttgatataaaaatgGAGCCAGTTGAAATAAAGATAGAGAGGCCCACATCGCCGAGCTGTGAGCTTCTGCCAATAGACTTTCCGGTAGTATTTATGGTGCCGCCGACGTTTCAGGCGGCGCCTGACTTGCCGTACCTCACGGAGCCGCTGCCAGAGTTGCTGCCCAGCAGTTTGATGCTTGATGACCCCGGGGAAGGGCCGTCAGGATTGGGGTCACAGATGCTGAGTATTCTGCCAGAGGAGGAGGTTAGAGAAGAGTTGGGGCAGCAGCAACAGCGGCAGCGGCTGCCGGCCTTCACGCAGGCGTTCCAGACGACGCAGAGCCCcaagccgccgccgccgccccctCCGCCGCACTAG
Protein Sequence: MASPPPNPRAGGDDGGGQDAGEDSPPASPKTVLAPPPPQHGTKLHYVALAAPGPSGIKQCFRTVKAARRVPTLPRRREEPGAPEPPSEPRERRARRDRSKRHVCGTCEKRFSSPGKLSQHVLSHTGELPFSCDLCDKRFNSKFKLVRHNLIHSEARAFACNVCGKTFNRKDHLTNHVRVHNPVKKLYTCERPDCRKSYTSLLSYRKHAALHSAEEGNLQCKICDEVFTTTQDIVYHLKVHTGSRTVKNETDKKFTCTYCERRFFTAKDVRRHQVVHTGRRDFLCPHCPQKFGRKDHLVRHVKNAHPEEPWRSAAVGTSKDPTPEGISYDEIVIPEPASYTEYAIESPDYTWKSPSPKDSTPEGPTRVPSSDIIVEIQPDFDIKMEPVEIKIERPTSPSCELLPIDFPVVFMVPPTFQAAPDLPYLTEPLPELLPSSLMLDDPGEGPSGLGSQMLSILPEEEVREELGQQQQRQRLPAFTQAFQTTQSPKPPPPPPPPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00654642;
90% Identity: iTF_00680966; iTF_00148742; iTF_00149783; iTF_00773182; iTF_00289991; iTF_01072904; iTF_00654642; iTF_00658802; iTF_00656488; iTF_00657612; iTF_00659732; iTF_00660640; iTF_00411827; iTF_00412833; iTF_00410686; iTF_00409625; iTF_01134109;
80% Identity: -