Basic Information

Insect: Lathronympha strigana
Gene Symbol: Bcl11a
Assembly: GCA_949128165.1
Location: OX421925.1:5975423-5981840[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2 1.7e+02 4.2 6.2 1 12 176 187 176 201 0.77

2 15 2.2e-06 0.00019 23.0 3.3 1 23 207 229 207 229 0.97

3 15 2.8e-05 0.0025 19.5 1.1 1 23 235 257 235 257 0.98

4 15 5e-07 4.4e-05 25.0 4.2 1 23 263 285 263 285 0.99

5 15 0.0015 0.13 14.0 1.2 1 23 311 333 311 333 0.98

6 15 0.00057 0.051 15.3 1.6 1 23 339 361 339 361 0.93

7 15 1.5e-05 0.0013 20.3 0.8 1 23 367 389 367 389 0.98

8 15 0.013 1.2 11.0 0.6 1 23 395 417 395 417 0.97

9 15 0.0099 0.87 11.4 5.4 1 23 423 446 423 446 0.94

10 15 2e-05 0.0018 19.9 1.8 1 23 454 476 454 476 0.97

11 15 0.31 28 6.7 3.8 1 23 497 519 497 519 0.88

12 15 8.3e-06 0.00073 21.1 1.7 1 23 525 547 525 547 0.98

13 15 5.1e-06 0.00045 21.8 1.9 1 23 553 576 553 576 0.97

14 15 4.5e-05 0.004 18.8 0.5 1 23 582 604 582 604 0.98

15 15 3.3e-05 0.0029 19.2 1.4 1 23 610 633 610 634 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2	1.7e+02	4.2	6.2	1	12	176	187	176	201	0.77
2	15	2.2e-06	0.00019	23.0	3.3	1	23	207	229	207	229	0.97
3	15	2.8e-05	0.0025	19.5	1.1	1	23	235	257	235	257	0.98
4	15	5e-07	4.4e-05	25.0	4.2	1	23	263	285	263	285	0.99
5	15	0.0015	0.13	14.0	1.2	1	23	311	333	311	333	0.98
6	15	0.00057	0.051	15.3	1.6	1	23	339	361	339	361	0.93
7	15	1.5e-05	0.0013	20.3	0.8	1	23	367	389	367	389	0.98
8	15	0.013	1.2	11.0	0.6	1	23	395	417	395	417	0.97
9	15	0.0099	0.87	11.4	5.4	1	23	423	446	423	446	0.94
10	15	2e-05	0.0018	19.9	1.8	1	23	454	476	454	476	0.97
11	15	0.31	28	6.7	3.8	1	23	497	519	497	519	0.88
12	15	8.3e-06	0.00073	21.1	1.7	1	23	525	547	525	547	0.98
13	15	5.1e-06	0.00045	21.8	1.9	1	23	553	576	553	576	0.97
14	15	4.5e-05	0.004	18.8	0.5	1	23	582	604	582	604	0.98
15	15	3.3e-05	0.0029	19.2	1.4	1	23	610	633	610	634	0.96

Sequence Information

Coding Sequence: ATGGAGGAGTTGCACTCGTGTAGTTGTTGCTTGGTTCGTCCTCCGGAGAAGGGGCTCAAGACGCTGTATAAACATCTAGGCAAAACAGAGATATATTACGAAATGCTGAAAGACTGCTTCGATATAAACCTCGGATTAGGAAATGAAGAATGTGGGATCTGCGATGTGTGCGTGGCACGGCTGCGGGACGCGAGCGACTTCAAACACCAAGTGCAGCGCAGCCAGTCGGCGCTGCACGCGCGGTTCAAGGGAGTACTCACTGccaGTGACAAGCTTAAAATCAAGTTGGAGAAAGCGGCTGGAGATGAAGCCGCCAGAACAGACGATATTAAACTGGAGAAGTCCGAGGTGGAAATGGCTGATGGAGAGGTCGTGTCAGTGGCTATATACGCCGAACCACCAGGCCGTTCAGCTGAGCCAGTTCCTACCGCGTCCAAACGAGATTCCATCGCGTCAGAGACCACTCTCTCTGACCTTGACGACTCCGAGCCGGCCCCGGCGTCCAAACGTAGCAAAGCTAAAGTACACAAGTGCGATATATGCCAGAAAACATTTTCCAAAACAAACGCAAAAACCCGACTCATGATCCATCGCCGCTCACACACAGGAGAGAAACCTTACACGTGCAATGTCTGCGACAAAAGATTCGCACAAAAAAGTCATTTAAATACTCATTACGCATACCATATGGGGAAGTTCAAGTTCTCTTGCGAACTATGCGATGGACGATTCACGCAGAAAAATCAATTTGTTATACACATGCGGACACACACTGGCGCAAGACCGTACTCGTgtgatttatgcaataaaacGTTTAGACAAAAAGGTCATTTAACTGTTCATCAAAGGAAACATTCGAAATATGACCCTAATTCTATAGAACCAGGAGAAATTACTTGCAAAACAGAGTTTTCAGAAGATGGTAAATATTTCACATGTGACATATGCCAAAAGCAATTCGCGGAAGAAACCACTTTTAACGCTCACAAGAAAAATCATATTGGTGACTATCCATTCGCATGCGAAACTTGCGAAAAGAAATTCAGTTCACAGTTTGCCTTGAATAATCATAAATTTGAACACACAGGAGGGAAACCTTTTAAGTGCGAAAAATGCAGTAAGGGGTATACATCAAAAGGGGCTTTGAGACTCCATTTGAAAGTTCACAATGAAGATTATAAGTTCGCATGCCTCGTTTGTTGTaaacgttttataataaaagaCGCTTTAAGTGTTCACATGCGAGTACACACCGGAGAAAAGCCTTACACCTGCGCacaatgtcaaacaaagttCCGATACAGATGTAGCTTAAAGAAACATTTGTTGGACAAACACAACCAAGTTATGGACAAACAGTTCTGTTGCGATATCTGTGGCAAACGATTCGCACTACAAGGAACCTTGTCTAAACATATGGACAAACACGCCGATCAACAAAAGGAGGAGGAAGCCAAAAAGGAAGGGAGGTTGGAAGACCTAAAACCATTCATGTGTGAAATATGTAGCCGACGATTTTCGACGAAAAATATCTTGAAATGTCATAGAGATACGCACTCCGAAGAAAGGCCTTTCGAATGCGAGATATGCCGTAAGCGATTTAGAATGAAAAAGTATTTAGAGGATCACATGAAGGTGCACGAGGACTTCAAACGACATTCTTGTGAAGTGTGCGGACAGCAGTTTAAACATAAGTCTGCCTTGGCCGTTCATATCAGACGACTCCACTCAGCTAGTATGCCGCATACTTGTGATGTGTGTGACAAGTCTTATCCAGTAGTTGCTGAATTAAAGAAACATTATCGAGTACATACTGGAGAGCGGCCATTTGCTTGTGAGATATGCTATAAGAGATTTCCTCGGCAAGATGGCGTCCGGCGACATCTTAGACGAGTTCATCATGAGAAACCTACaaagtttattaaattaaaagaatttaATAATCCATATTAA
Protein Sequence: MEELHSCSCCLVRPPEKGLKTLYKHLGKTEIYYEMLKDCFDINLGLGNEECGICDVCVARLRDASDFKHQVQRSQSALHARFKGVLTASDKLKIKLEKAAGDEAARTDDIKLEKSEVEMADGEVVSVAIYAEPPGRSAEPVPTASKRDSIASETTLSDLDDSEPAPASKRSKAKVHKCDICQKTFSKTNAKTRLMIHRRSHTGEKPYTCNVCDKRFAQKSHLNTHYAYHMGKFKFSCELCDGRFTQKNQFVIHMRTHTGARPYSCDLCNKTFRQKGHLTVHQRKHSKYDPNSIEPGEITCKTEFSEDGKYFTCDICQKQFAEETTFNAHKKNHIGDYPFACETCEKKFSSQFALNNHKFEHTGGKPFKCEKCSKGYTSKGALRLHLKVHNEDYKFACLVCCKRFIIKDALSVHMRVHTGEKPYTCAQCQTKFRYRCSLKKHLLDKHNQVMDKQFCCDICGKRFALQGTLSKHMDKHADQQKEEEAKKEGRLEDLKPFMCEICSRRFSTKNILKCHRDTHSEERPFECEICRKRFRMKKYLEDHMKVHEDFKRHSCEVCGQQFKHKSALAVHIRRLHSASMPHTCDVCDKSYPVVAELKKHYRVHTGERPFACEICYKRFPRQDGVRRHLRRVHHEKPTKFIKLKEFNNPY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01134026;
90% Identity: -
80% Identity: -