Lfle000537.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laspeyria flexula
Gene Symbol
-
Assembly
GCA_905147015.1
Location
LR989954.1:2433426-2441362[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.0011 0.074 13.9 2.7 1 23 201 224 201 224 0.97
2 30 0.00031 0.022 15.6 0.4 2 20 258 276 257 278 0.93
3 30 0.0017 0.12 13.3 0.2 2 23 313 335 313 335 0.97
4 30 0.54 38 5.4 0.7 2 19 352 369 351 372 0.83
5 30 0.0039 0.27 12.2 2.4 1 23 382 405 382 405 0.97
6 30 0.042 2.9 8.9 0.4 1 23 422 444 422 444 0.95
7 30 0.0012 0.082 13.8 0.9 2 20 484 502 483 504 0.93
8 30 0.0063 0.43 11.5 6.0 2 23 545 567 545 568 0.96
9 30 0.00096 0.067 14.1 0.5 1 23 617 640 617 640 0.97
10 30 0.0037 0.25 12.3 0.2 1 23 695 717 695 717 0.97
11 30 0.0064 0.44 11.5 7.2 1 23 728 750 728 750 0.98
12 30 0.016 1.1 10.2 1.1 2 23 762 783 761 783 0.96
13 30 0.0028 0.2 12.6 1.4 1 23 793 815 793 815 0.98
14 30 0.019 1.3 10.0 6.0 1 23 844 866 844 866 0.96
15 30 0.00091 0.063 14.2 2.6 1 23 877 899 877 899 0.98
16 30 1.3e-05 0.00089 20.0 0.7 1 23 907 929 907 929 0.98
17 30 0.0013 0.091 13.7 1.4 2 23 949 971 948 971 0.96
18 30 1.5 1e+02 4.1 0.2 1 23 989 1011 989 1011 0.90
19 30 0.11 7.3 7.7 3.7 1 23 1018 1040 1018 1040 0.97
20 30 0.0051 0.35 11.8 2.2 2 23 1051 1073 1050 1073 0.94
21 30 0.017 1.1 10.2 0.2 2 23 1096 1117 1095 1117 0.95
22 30 7.4 5.1e+02 1.9 5.6 2 23 1160 1182 1159 1182 0.95
23 30 0.0096 0.67 11.0 0.2 2 23 1198 1219 1197 1219 0.95
24 30 0.61 42 5.3 5.5 3 23 1227 1247 1225 1247 0.96
25 30 0.014 0.97 10.4 0.9 2 23 1258 1280 1257 1280 0.95
26 30 0.43 30 5.8 4.9 2 23 1297 1315 1297 1315 0.94
27 30 0.58 40 5.3 1.3 2 21 1319 1338 1319 1339 0.92
28 30 0.56 39 5.4 0.7 2 23 1388 1409 1387 1409 0.93
29 30 0.00037 0.025 15.4 0.8 2 23 1420 1442 1419 1442 0.96
30 30 1.9 1.3e+02 3.8 5.7 2 19 1480 1497 1479 1500 0.92

Sequence Information

Coding Sequence
ATGGCACTCAAACTTGGAAAATGCAGGCTTTGCCTCAAGCTTGGGGATTTCTACTCCATCTTTACGGTGGACAACTCCCTACAGTTGGCGGAGATGGCAATGGATTGTGCCAGGATAAAAATATACGACGGAGATGGGTTGCCAGATAAAGTATGTTCAGAATGCATACAGAAACTCAGCAGTGCTTATATATTCAAACAACAATGTGAACGCGCTGATCAGGAGCTGCGGAGGAACTATATACCACCACCAGGGTTCAGCATCAGCCCACAGCCTCCTAACAGACAAAGTAGCGATTCAGCATTCTCGAATCACACTGACACCTCAAACCTCACCAAACCTTCATCTTCTGTAGAAGATAAGATACCTCCTATATCCAAAAGAAAACGAAGTATCGAGAGTGATGGCAACACTTCGATTGGAGGCCGCTCTTCTGACTACAGGCCTACTGCCTCTAAACGTGTCGAGGAACTTAGAAACTCGCAAAAAAGGGCACGGCTACAGTCTGGCAATACCTCGCAACCAGACTCTGATTACGAAGACAACAGCGGATCGTACTTACCCGAAACTGATTCAGATGAACCACTCATGAAAAATAATTTTAAATGTAAGTCATGTCCCAAAGAGTTCTCAGCGTACAAGAATCTCGCGATACACATGTCTAGATGTCACAGCAGGAAAATCGGCTCGATTCTCGATCTCGGAGAAAATGCGGTCGTCGATATACCGAACAGAAGCAATGGGGATGCTGATGATGTAGAAGACAAGCTGAGCTGTGATATATGTGGCAAGACCTTCAAGTTAAAAATCATGCTGAAAAGGCACCACGATGTATGCGGGAAGACGCCGGTCAAAACACCACAGAAAGAATTGCTTATATCCTTAGAACCGATTGATGTTAAACAGAATATTATAGTCTCGACTCCACCTGCCAACACTTGTGAATATTGTTCACAGAATTACAAATCTATAGACGGTCTTGCTAAGCACATGAAAATAGTGCATGCCGCTGTGTTGAAACGAGAAGCGGAGCCGAACAGAAAAGTACCAGTACCTTGCCTCTATTGTAACAAAAGTTTTGACGATTATTACCAGCACAACTCACATTTTAATTTGTGTCCGAAATTGGATGATACGAAGCCGTTCGAGTGTCCCGTATGTCACAAGGTAATGTCTAGGAAGACGTCATACTACCAACATATCAAGAACATGCACTTTGAGCCGCGCGTGTCGCACGTGGAGGTGGAAGCAGAAAAAGAGTACCACGAGTGTAGGATGTGCCTGAAGAAGTTGGCGACGCAGGAACTACTCATCAAACATCTGGCGGCGCACGTGTCCAATATTGATGATGACGGTGCTGCTGATAATGAATCCAGAGCAAGCACTTTAGACGATTCCGCATCTGTGCGATCGGTACAAAGCAACAGTTACCCTGCGAGTGGTCCACTCAAATGTGAATTGTGCCAAAAAGAGTTCAAATATAAGAAAGCACTCAATACACACCAAGATAAATGTAAATCAGAAGTACCTATAGAAGTTAAAACGGAACCACCCGACAAAGCTTCTACTAGCCTTCTAAGCGAAAAGCAGTACCGCTCCGAGTCAGAATCTAGTCAAGAAGAGGAGGACAATACGTGTGATATTTGCGAGAAACAGTTCTCGTACAGACGTCTTTTACTTCACCACAAGAGAACGAAACACCACATGAGTTCTGGCCACAAGCGTGCCAAAATATATCTTAAAGACTGCTCGGTTCGCTGTCTCATCTGCGACATTGAGATGAAGGTGGGCGCTATAAACGAACACAATCAGACTCATATATCGAAGAACATGAAGCCTAGGAACCTGTACACTTGTGCGGAGTGCGAGACTACGTTCAAAGCTTGCAGCGCGCTCGCTAACCATATAAAGTTAGTTCATAGGTTGAAGCAAAAAGTTGAAGAGGAAAATTCGGTTAATCCGTCGGATTTTTGTGAAGTCGTTGTGACCAAGTCGGAACCCCTGGACTGGATCCAGAGTCACAACGACTTTGGTGAGGTTCCGATAGTACAGGACGGCAAGCCGCTGGTAGACCTGAGCGGGTTCACGTGCCCCATCTGTGAGAAGAAGATGCCGACGCTTATATCTCTCAAGAGACACGTCAACTGGCACACTAACGTTGGCAAGAATTTGGAGAAGAAGTACGAGTGCTTTGTTTGTAAAGAGTCATTCAGATTCCAATGTCACTACAAGCTGCACATGCGCGAGCACTACACAGACACAAACTTGGACCCCGCGCACCTCACGTGCAACATCTGCGGCCGCCGCAGCAAACATCTGCGAGCTGCGCAGGCGCACATGACCTACCACAAACAGACGCGCTTCAAGAACAAGGACTACCAGTGCTCCATATGCGAGAGAGTGTTCCAACACAGGAAGGTGTACCTCTCACACATGGCTGTACATTACAAGAAAGGTGACGGAGCGCAGAACACTGTGATAGGTGACGCTCAACCCATCAACTCGTATAAGGAGACCATCAACAGTCCACACACGTGCCCCCACTGTCGCAAAGTATGCGACTCCGAAGTGTCGTTAAAGCACCATCTGATCTGGCACAACTCTAAAACGTTCCTGTACGGCGCTCGCCACGAGTGTCCAATATGCAAGGTCAAGTACACCAACAAGAGGCGCCTGGAACTGCATACGCGAACACACTACGAGGACGACAATGGACCTTACAAGTGCAACATCTGCGGCAAAGGATATACGGACGAGGGCTACTTCAAGAAACACGTCAAGGGTCACAACTTCGACCACCAGTCACACAAGAAGAGAATAGAAAATATCAGGAAGGATAAAGTGAAGTGTCCGATATGCTCGCGGTATTACAAGGATTTAGTGAAACTGATCCGTCACCTGCGGCATACTCACCCTGAGAGTAAGATGATCAAGACGGACCCCGACGCGCCCACACAACCTTACTTCTCGTGCAAACTGTGCGCCAAGATGTTCCTCGACGAGCGCAGGCTCCAGGCACACGAAGAGGCGCATCTCAGGAAGCCTGAATTCTTCAAGTGCAAGTTCTGTGGGAAGAAAACTATATCTCTAAAGAATCATAGAGTTCATATAAAGGGGCACTTGACGCAGAAGTATGTGGACAACCCACTCAAGTGTCAGCACTGCGACGAGACGTTCGAGCGCGGCTACGACCTGCACTACCACGTCAGGGATGTGCACGGCTTCGAGGAGACCTGGATCGCCGAGCGAACTGAACAACGCCTCACAGGACCCCTCAAGGACCTGCAGTGCTCCATATGTATGAAAGTGCTCGCAAGCAAGGGCAATTTCGAGCGACATCTCGACTATCACAACTCGTTGCGATGTAATTACTGTTTCGATTACTTCAGCTCTCTCAGATTCTTGGAGGGACACTTAGCGTTTTCTTGTGAAAAGAAAAAACTGTTGGGCGACACGGAGGTCTATCCAAAGAAAATAAAATGTCACGTTTGTTACAAACCCTTCCATGTGCAAGTGAAGTTAGATTGTCACCTGCGCACGCAACATAACATTAAAGTGTCCAAGGAGCAATCTTCTGGGAAAAAAGAGATTGTCTGTGACTACTGCTTCAAAGTGTTCGAGAATGATTACGCTCTGTCCACACACAAGATTTACCACCGCACCATTGGCTACTTCGGGTGTCTGTATTGTAAAAGAAAGTTTAACACCATGACTCTTTACCGTAAACACAAGAACCACCACTTTGCGCAGCTGAACGTCGACGAGCCGACCAAGTGTGAGCACTGTGACGAGACGTTCGTGGCCTTCAGAGACATGATATACCACATGAGGGACGAACACGGCGACGACAAGGACTGGGTGACGTTGCCGAAGGAGTCCATAGAAGAGACATGCACTATCTGCAACAAAACGTTCTTCAACTTGCACAGACACATGACGTATCACGAAGAGAACAGATGTAAGAAGTGCGGCGAGTATTTCTTCTCGACGGCGGACTTCGACAACCACTTGTGTGCCATAGAGAGTGACGACGAGGTGAACTCCTCCGTGACCACGTACGAGCGACCCAAGTACGAGGAGTGCGACTTCTGCTTCAAGCCCATCACCAGGAAGAGTTCTAAAGCGAAGCACGACCACATACACAAAGGATCCGGTTCTATATCGTGCAGGTTCTGTACGCTCAAGTTCAAGACTATAGACGCGTTCAACATCCACGCCTTCTCTCACAGAAGCAGAAAGTACAACAAGAAGCCGATCAAGTGTAGGAAATGTGGCGAGAAGTTCGTCAAGTATGGGTTGTTTATGAAGCATATGAAGATCATTCACAAGTCTGTCAAGAAGATGCACTACAGGGCGGTGGTGAAGCCGGAGCGGTGCGTGGTCTGCGGCGGGATGTTCCCCAACTTGCACAACCACTACCGCGCTCATATGGCCAACCAGTGCCACTCGTGTCACAAGTACTTCACTTCATCCAAACTGTTCTCTTTACACGAATGTGACAAAGAGGACTCCGATCCTTCCAAAGTGTTCACTAGTGACGTGAGATTGAATGATTTGATAAATTCCTACGCTCCTAAAGATGAGAAGGATGATGAGAAGTACTACGGTCACACTGACGATGAGGAGGAGGAAGATGAAGAGGAAACGTTGGTGGTGTGCGGCGAGGACGACGACAGTCAGGACTGTAAAGATTTCAAAGATATTGACATCGAAAAAGATATAACTATGCAGCCATTATCGATTCAATCTCCGATAATATCTGATGTGTTGTCACTGTATCAGAAGGAGATGAACCTACCCGCAGTAGACGATAATGTGGTGACCCTCACCGATGATGACTCTATGGACGTAGACCACGTCCAGAGCCAACCTGAGACCATCGTAATTATTGATGATGATGATGATTAA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNSLQLAEMAMDCARIKIYDGDGLPDKVCSECIQKLSSAYIFKQQCERADQELRRNYIPPPGFSISPQPPNRQSSDSAFSNHTDTSNLTKPSSSVEDKIPPISKRKRSIESDGNTSIGGRSSDYRPTASKRVEELRNSQKRARLQSGNTSQPDSDYEDNSGSYLPETDSDEPLMKNNFKCKSCPKEFSAYKNLAIHMSRCHSRKIGSILDLGENAVVDIPNRSNGDADDVEDKLSCDICGKTFKLKIMLKRHHDVCGKTPVKTPQKELLISLEPIDVKQNIIVSTPPANTCEYCSQNYKSIDGLAKHMKIVHAAVLKREAEPNRKVPVPCLYCNKSFDDYYQHNSHFNLCPKLDDTKPFECPVCHKVMSRKTSYYQHIKNMHFEPRVSHVEVEAEKEYHECRMCLKKLATQELLIKHLAAHVSNIDDDGAADNESRASTLDDSASVRSVQSNSYPASGPLKCELCQKEFKYKKALNTHQDKCKSEVPIEVKTEPPDKASTSLLSEKQYRSESESSQEEEDNTCDICEKQFSYRRLLLHHKRTKHHMSSGHKRAKIYLKDCSVRCLICDIEMKVGAINEHNQTHISKNMKPRNLYTCAECETTFKACSALANHIKLVHRLKQKVEEENSVNPSDFCEVVVTKSEPLDWIQSHNDFGEVPIVQDGKPLVDLSGFTCPICEKKMPTLISLKRHVNWHTNVGKNLEKKYECFVCKESFRFQCHYKLHMREHYTDTNLDPAHLTCNICGRRSKHLRAAQAHMTYHKQTRFKNKDYQCSICERVFQHRKVYLSHMAVHYKKGDGAQNTVIGDAQPINSYKETINSPHTCPHCRKVCDSEVSLKHHLIWHNSKTFLYGARHECPICKVKYTNKRRLELHTRTHYEDDNGPYKCNICGKGYTDEGYFKKHVKGHNFDHQSHKKRIENIRKDKVKCPICSRYYKDLVKLIRHLRHTHPESKMIKTDPDAPTQPYFSCKLCAKMFLDERRLQAHEEAHLRKPEFFKCKFCGKKTISLKNHRVHIKGHLTQKYVDNPLKCQHCDETFERGYDLHYHVRDVHGFEETWIAERTEQRLTGPLKDLQCSICMKVLASKGNFERHLDYHNSLRCNYCFDYFSSLRFLEGHLAFSCEKKKLLGDTEVYPKKIKCHVCYKPFHVQVKLDCHLRTQHNIKVSKEQSSGKKEIVCDYCFKVFENDYALSTHKIYHRTIGYFGCLYCKRKFNTMTLYRKHKNHHFAQLNVDEPTKCEHCDETFVAFRDMIYHMRDEHGDDKDWVTLPKESIEETCTICNKTFFNLHRHMTYHEENRCKKCGEYFFSTADFDNHLCAIESDDEVNSSVTTYERPKYEECDFCFKPITRKSSKAKHDHIHKGSGSISCRFCTLKFKTIDAFNIHAFSHRSRKYNKKPIKCRKCGEKFVKYGLFMKHMKIIHKSVKKMHYRAVVKPERCVVCGGMFPNLHNHYRAHMANQCHSCHKYFTSSKLFSLHECDKEDSDPSKVFTSDVRLNDLINSYAPKDEKDDEKYYGHTDDEEEEDEEETLVVCGEDDDSQDCKDFKDIDIEKDITMQPLSIQSPIISDVLSLYQKEMNLPAVDDNVVTLTDDDSMDVDHVQSQPETIVIIDDDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01502316;
90% Identity
-
80% Identity
-