Lfle009201.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laspeyria flexula
Gene Symbol
-
Assembly
GCA_905147015.1
Location
LR989952.1:5475348-5484250[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.0061 0.42 11.6 1.1 3 23 689 710 688 710 0.96
2 22 0.23 16 6.6 0.3 1 22 1091 1112 1091 1112 0.95
3 22 7.2 5e+02 1.9 0.2 1 22 1154 1175 1154 1177 0.82
4 22 0.0023 0.16 12.9 2.1 3 22 1188 1207 1188 1207 0.96
5 22 0.044 3 8.9 0.3 3 23 1257 1278 1255 1278 0.96
6 22 0.0021 0.14 13.1 2.5 1 23 1284 1307 1284 1307 0.95
7 22 0.14 9.5 7.3 0.0 1 23 1333 1356 1333 1356 0.90
8 22 0.006 0.41 11.6 3.5 1 23 1361 1383 1361 1383 0.97
9 22 0.085 5.9 8.0 0.1 1 23 1389 1412 1389 1412 0.95
10 22 0.0025 0.18 12.8 1.3 1 23 1425 1447 1425 1447 0.97
11 22 0.00019 0.013 16.3 1.8 1 23 1501 1524 1501 1524 0.97
12 22 0.0052 0.36 11.8 1.7 1 23 1584 1607 1584 1607 0.96
13 22 0.0026 0.18 12.7 2.1 2 23 1634 1656 1633 1656 0.95
14 22 0.095 6.6 7.8 0.1 2 23 1662 1684 1661 1684 0.93
15 22 0.089 6.2 7.9 0.1 1 21 1728 1748 1728 1749 0.94
16 22 0.00046 0.032 15.1 1.0 1 23 1759 1781 1759 1781 0.93
17 22 0.00012 0.0084 16.9 0.3 2 23 1871 1893 1871 1893 0.93
18 22 4.3e-07 3e-05 24.6 1.4 3 23 1900 1920 1899 1920 0.98
19 22 0.016 1.1 10.2 0.6 1 23 1939 1961 1939 1962 0.94
20 22 0.13 9.1 7.4 0.0 1 23 1985 2007 1985 2007 0.97
21 22 0.03 2.1 9.4 0.6 1 23 2013 2036 2013 2036 0.95
22 22 0.00028 0.019 15.8 0.4 1 23 2044 2067 2044 2067 0.96

Sequence Information

Coding Sequence
ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCTGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCTACAAATGTCTGCAGGAAATGCATGGATAATGTCAATAATTGGCATAAATTTAAAAATGTATGTGAAAGGACACAAAACAAACTACAGTCTCTGATTAGTAAAGATGGCAGCCAACTAGAAGAGGTGAAAATAAAGAGTGAGCCATTGTCTGATGAAGCCTATGATGATGGAGTGGTCATTGATGGTTCATACCCTGACAGTGAGAATGCCAGTCCGGCAAACAAAGTTCAACCTGAAGGTCCCCCGATCCTGGCTTCATTGGGGCTCACACCAAGGAGTGATAAGAAATGTGTGGATCCTCGAATGGATTGGCACCGGGTCCATGCTATCTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTACAATCAAAGGAAGAGTGTGATGTTTTGCAACACTCTGATCATGATTCTGACACAGACGCTGAACTGCAACCAGACATTGAGGATGACTATGTAGATTGCAAAAGCGGCTATTTATGCAAAAATAAAAAAGTTTTAATGAAAAATCCAAAACTATCCCCGTCTATGAATAACATCAAAATCAGAGAGGCTCTTGAAGTTAGGAAACGCAATATGGACTTACCCAAACAACATTGCCCACAACCCAAAAATGCTTGGCAGTTGTTATTTACTGATGACCTACTAGAATTAATTGTCACTTCAACCAATGAAAATATTATGCAAAGTGGAAAAGGTAACTCAGTTGCAACTAATGTCAGCGAAATAAAAACTCTTATCGGCATTTTGTATTTACATGGTATAATGCGGCCGACGCATCAGAAGTGTACTGACCTTTGGAGTAATGAATGTGGTGTACCTTGTATTAGAAATTCTATGAAATATGACAGGTTTAAATTCCTTATACAAAACTTATGTTTCGACAACGAGGACGACGACAGCATTATACAGTATGACATTATGAAACGCATGCGCAAGGTATTTGAAATCTTCGCCATGAATTGCAGAACAGTTCATGAGATCGAGAATGTTGCGGTAATTGATGAGATCATCGTGCCAGTTTATGGACCTTGCCCATTTCGATATGATATTGATAAGAAACCGCTGAAGCGCGGCATAAAAATGGTGTTACTTGTCGATTCATCCACATTCTATATGAGCAATTTAGATGTCATTACTGACCCCTACTTCGGGGCCGAGGAGATAACCAACAAGCTAGTTCAGCATTTAGCTGGATCAGGTAGAATTATTGTTATGGATAGTTGGTTTACATCAACTCCATTAATGGAACGCCTAAGGAATGAATATCAGTTATTTACCATAGTTGCTTTGAATCCAAACAATGACTGGATTCCACCTTTGTTTCTTTCACAGTACAGAAAAAGTAGAACTTTTATGTCTGGATTTGTTGATCATGAAGTGTCACTTACATCTTATGTAAATTCTGAATTGAAAGCAATAAATGTGATGACAAATGAGCCCAGATTTTATAGAAAAGGTCATGTGAATCAAACTACTGTTGTATCGGTCTATAAGAAAAACCAGTCAGCGGTAGAAGTTATTGATGTTCTTATGAATTATTATACAACCATGCAACATACGAATGATTGGACTTTGTCCCTCTTCTTCACCCTATTGAACATAGCTTCAGTGAATGCTCAGGTGCTATGGAGTAGTCAAAATAATAATGTGGCCCAGCGTCGTCTATTTATTAAAGACTTAGCTTTGAGTTTGTTAGTGCCAGACGAAACCATGCCAGGAGTGGAAAGTGACAAAGAGGAGGAAGAGGAGGATGGAGACGAAGAAGAGTTAAATGAAGTTCCTCCACCGTTCCCAAAAATGCCTCATATGCCGGAGGTATCTATAACGGTGATGCGGCCCACGGGTGAGACGCTGCACGCCCGGCAAGGTATCCACCAGCTCGCTTCTAAAGATTGTCTCGTGTGCGGCCGTACGTACAGGTACTCCCACAATGCCCGGCGACATGAACTTACCGCTCACAGTTTCGACAGATACACCAATAAAATAACGCCCAAAAAGAATTTACCTCATCTCCAACCAAAATTACGACCTAACCCGTTTAACCCTAAAGCGCGGTGGAGGCCGAATCCTATTAGCCATAAGATGCAATTTATGTCGACCACTATCCCAACAAAAATAGTGCCCAGTAACAAAGTTATTGCGCACGTTAAACCGGCAAAATCGGTAAAATCGGCCCAAAATAAGTTACCGTATCCTCTACGTATCAAAGCTCTTAAAGATTTACAAATTAAAAAGAAGGAGCCTCAAATTTTAAAGACATTGTTGACCTCTAAACCTGAGGTTCTAGTCTCGGAACCGGAGATAATAAACTCTGGGCCCGAAAGCCCAGAAACATTAATATCGGAGCCGGAGATTGCGTCTTTCCAAGTGGAGGCAATACTTTCCGAGCCTGACGGTGATGGTTATGAACATCAGGGTGACGATGATGTGGATGGTGAAATGCATAATAACCAAAGCCAGCATTATGACACGGTGGACATGAATTCTGAAAATGAAATCGAGATTGCTCGACAGCAGAGTAATGAGGATCATATAGGAGACGAAAATAGTGATGGTGATGAAAATATTGATCAAGATGAGGATGATAATATGGATGGTGGTCAGAGTGATAATGACCAAGATGGTGTTGATGATACAGCAGACAGTCAAGAAATGGAAGATGGCCTCGACATTAAGGCTGAACAAGAGATGAAGGAGGGTGATGAAATCAATGAGGAAAGGGACCATGAAGAACAAGAAGAAATGGAAATGAATCACGATGAGAATGAGGATGACGATGACGACCTCCCAATATCGATACAACCTGTCGTGGAAATTAACGAAGACTTACAAGTTAACTCGTTAAACAACGAGGGTGGCGAAGAGGATGATGAACTTGACGAGAGTGCTGATCCAAATGAAACCATCGACGAAGAGGAGATCAAAGAACTCGACCCTAACAAAACTTATGTGACCAAAACGCAACGAGACTTCATTCTTAAGTATCGTGACATAATCCAACAAATTAATACGAAGCGTTGTTTGTGTTGTGATAGAGAACATCCGAGAAGGAAAGCTGTTATACAACACTTACAGAAAAATGGTCACAAAGTTCCCAAGCACACGTGTTATAATTGCGTAATCACATTTGGGCATATTGGCGCACTACTTAGTCATATGAGATCGAATTCTTGTACCAATTTGTGGAAGATTATTTACAATGAAAATGGTATTACTGACGATTTAGTTCTAGAGGATGAGCCCAAGGAAGTGAAAGTTCAATATAAAGATATTTTCAATGCGAGATCCTACGCTTGTAAACTATGTCCAGCGAAATTCCAATTGAAACAGTTCATAATGAAACACGTATTAGACGCACATGAAGATGGACAATCTAGGGTTCCTCTTGGTTGTGTTCATTGTCGTGCTAGGTTCAAAGATAAAAGTTTGCTTAAAAAGCACATTCGTAAAGGCGATTGCACTGTATATGTAGCTTGCGATTTATGTCCAGAACAGTTCCTGAATATGCAGGACTTTAATGATCACGCATTAGCGGTTCACGCCGGTAGTTTCGAGTCAGATAGCCAAAGCAAATGTGTTGACGGTCGCCCTACTGACTGCACATTGTGCGGCAAGAAAAATAGCAGCTATCCTAATTTAGTGAAACATTTGAAAATTATTCATAATGAAGAAAAACCACATTATTGTCAGCATTGCGACTCTAAATTCGAACAAGCTGCAGATCTTAACAAACATATTTACATGGAACATTCTGACCGATCACTAGGCATGCAAAACAATGAACCAGATATGTCCATTGTTAAGGAAGAGGCGGAAGAGTATCATTATTCTTGTACTGAATGTAATGCGATATTTGAAACTGTAGATGCATGGACCGACCATCAGGTGGCCGAGCACAACCAAGTGGCCCACCACTGCGACCAGTGCGACAAGAAATTCTTGCGTCCTTCCGAACTCGCTGAACATAAGAACACTCACCTGAGAGTTAAGTTCTACCCTTGTAGCGTATGTGCTAATTCTTACAGTACACCTCAGAAATTGTCCGAACATGTACAGCAAGTTCACCCTGGTATCGGCGCAATCGCCGCTGCTGATTCAGAATTTTTCTGCGACATCTGTATAAGGTCATTCAAAAGTCGTCAAGCGTATTCTAACCATATGCGTATACACGCCAAAGTGCCTACTACAAATAGAAAACCTGGCGATCCGCCCAGTAAAAGAAATGAATTTTCACCATCGATCATCGGTAAACCCATTAAACAGGTTTACCCGATGGTGCAACCTGGAGTTGTGTCGTTCAAGCCACATTATAATATTCCTAATGCTCCCTATTCATGTGATATTTGTGGAAAAGGATTTATGCACAAGAAGAATATATGGAAGCACAAAAAAGTATTACATGCCGATATATTGAACGACAGGAATGATAGTGAGGAGAATACTATGCAAGCGTCCACCGAGGAAGACGAGTTTAATCCAGATGAAAATGGAGCTGTGCTCTCCACACCTCAATTTAATAGTTTCAACTTTACCAATTTCCCAAATAACGTCCAGCAACCGCAACAGGATGCCATGCCCTATTCATGTGAATTATGTTTCAAACGATTCCCACTCAGAACTAGTTTATGGAAACACAAACGCGCCAAACATGGAATCGTTAATCCGAACTCTAGCGGCAGTACGGAGGCTCAAACGCCATCGGGTAGTGGTGAAGGTAGTAGCCGATCTAGTTGTACAATTTGTAGGATTACATTTTCAGATAAGAAATCTTATTATCGTCATCGAAAGAATGTCCATAAGTCGACAGTTCAAATGTGCAAAATTTGTGGTAAACCTCTTAATTCGACTTTGGAATTGTATGAGCACTTAAAGGCTGCTCACGCAAGAGAACTGCTAGGTTACAATGCTAATCAAGGTTCCAGTAAAACTCAAGAGGTAGTACCAGAGATGGAAGTCGAATATGAGAATGATCAGGAGCCTATAGACCCTAGCGTGGATTATCAGGCTCGTTACCCTTGTGATGCCTGTGGCAAACAATTCGTTGGTTTGTTAGCTTTGCAAAACCACCAGTGCATAAATCAGGCACCGCCACAACCACAAACGTTCGATTGTGAAATCTGTCACAAGAGTTACACATCAATATCGGCATTAAAAAGTCATCGCGGATGGCATTTACGTTCACCTGATGGTAAAGCAGCCGCTAACAATAGCGGACTTTGGATGCCACAACACAAAGTTACGAGCAAAATAAGTAAACATGAAGTTGTCGATGCAACGACAATTGCCAGGCCTGTACCCGCGGGCCCCGCTGCTACGGTAACAGCCAAAAGAAGATTGCCACCAGAAGTCGAAGTCACAGTTGTCAATCCAAATAAGAAAATGCGCTCCGACGATTCCGTAGAATTAGAGCAACATAATTCTAGCTCTGCCGAAGATAGATATTGTACAATTTGTGATAAGGAGTTTACTAAGCGAGCGGCATATCAGCGTCACATGGACGAAGTTCATCAACCTAATTCTGTGTTTTGTCCGGTTTGTGATAAGAGCTTTACCAGAAAGTCGACATTGCTTATCCATATGAAGAAACATTATGAAACTGGTGAAGGCAGTTCAAACGCAACTGGCCAAGGCGAAGAGGAAACGCACACATGCGATTTGTGCGGTGCTCAGTATGATGACGAAGAAGCGTTAAGAGCGCATCGTGTGAGGCACCACGGCGAAGAGTCGGAGGAAGAAGACGACGGAGACGATGGTAACGTGCCCATAGCTCAACCAGGAGAATTCACTTGTGGTCAGTGTGGAGATGGCGTGGCTACACCTCGGGACCTGATCGCTCACCGCACAATGCATGCTACTCCCACCAAATTTTTCTGTAACATTTGCAAAGTGTACTTTGCGAGAGCACTTGACCTCTCCTCACATACAAGGGCGAGACACGCCGATAACGAGAAGGTATTTTTTCCTTGTGCCATGTGTGACAGATTTTACATGAACAAGAAGAGTTTACAGCGGCACATTGAGATGGCTCACTGA
Protein Sequence
MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHKFKNVCERTQNKLQSLISKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPDSENASPANKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQSKEECDVLQHSDHDSDTDAELQPDIEDDYVDCKSGYLCKNKKVLMKNPKLSPSMNNIKIREALEVRKRNMDLPKQHCPQPKNAWQLLFTDDLLELIVTSTNENIMQSGKGNSVATNVSEIKTLIGILYLHGIMRPTHQKCTDLWSNECGVPCIRNSMKYDRFKFLIQNLCFDNEDDDSIIQYDIMKRMRKVFEIFAMNCRTVHEIENVAVIDEIIVPVYGPCPFRYDIDKKPLKRGIKMVLLVDSSTFYMSNLDVITDPYFGAEEITNKLVQHLAGSGRIIVMDSWFTSTPLMERLRNEYQLFTIVALNPNNDWIPPLFLSQYRKSRTFMSGFVDHEVSLTSYVNSELKAINVMTNEPRFYRKGHVNQTTVVSVYKKNQSAVEVIDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQVLWSSQNNNVAQRRLFIKDLALSLLVPDETMPGVESDKEEEEEDGDEEELNEVPPPFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRTYRYSHNARRHELTAHSFDRYTNKITPKKNLPHLQPKLRPNPFNPKARWRPNPISHKMQFMSTTIPTKIVPSNKVIAHVKPAKSVKSAQNKLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEIINSGPESPETLISEPEIASFQVEAILSEPDGDGYEHQGDDDVDGEMHNNQSQHYDTVDMNSENEIEIARQQSNEDHIGDENSDGDENIDQDEDDNMDGGQSDNDQDGVDDTADSQEMEDGLDIKAEQEMKEGDEINEERDHEEQEEMEMNHDENEDDDDDLPISIQPVVEINEDLQVNSLNNEGGEEDDELDESADPNETIDEEEIKELDPNKTYVTKTQRDFILKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDAHEDGQSRVPLGCVHCRARFKDKSLLKKHIRKGDCTVYVACDLCPEQFLNMQDFNDHALAVHAGSFESDSQSKCVDGRPTDCTLCGKKNSSYPNLVKHLKIIHNEEKPHYCQHCDSKFEQAADLNKHIYMEHSDRSLGMQNNEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCANSYSTPQKLSEHVQQVHPGIGAIAAADSEFFCDICIRSFKSRQAYSNHMRIHAKVPTTNRKPGDPPSKRNEFSPSIIGKPIKQVYPMVQPGVVSFKPHYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILNDRNDSEENTMQASTEEDEFNPDENGAVLSTPQFNSFNFTNFPNNVQQPQQDAMPYSCELCFKRFPLRTSLWKHKRAKHGIVNPNSSGSTEAQTPSGSGEGSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLNSTLELYEHLKAAHARELLGYNANQGSSKTQEVVPEMEVEYENDQEPIDPSVDYQARYPCDACGKQFVGLLALQNHQCINQAPPQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDATTIARPVPAGPAATVTAKRRLPPEVEVTVVNPNKKMRSDDSVELEQHNSSSAEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYETGEGSSNATGQGEEETHTCDLCGAQYDDEEALRAHRVRHHGEESEEEDDGDDGNVPIAQPGEFTCGQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00017541;
90% Identity
-
80% Identity
-