Lfle008620.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Laspeyria flexula
Gene Symbol
-
Assembly
GCA_905147015.1
Location
LR989957.1:11590945-11608442[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 8.5e-05 0.0059 17.4 2.2 1 23 428 450 428 450 0.97
2 20 0.0044 0.3 12.0 0.6 1 20 456 475 456 478 0.94
3 20 2.2e-05 0.0015 19.3 5.6 1 23 497 519 497 519 0.98
4 20 0.0001 0.0071 17.2 4.1 1 23 525 547 525 547 0.99
5 20 3.9e-05 0.0027 18.5 5.3 1 23 553 575 553 575 0.97
6 20 1.2e-05 0.00083 20.1 7.3 1 23 581 603 581 603 0.97
7 20 7.5e-07 5.2e-05 23.9 2.9 1 23 609 631 609 631 0.97
8 20 0.00011 0.0074 17.1 6.7 1 23 637 659 637 659 0.97
9 20 0.00011 0.0074 17.1 6.5 1 23 665 687 665 687 0.97
10 20 5.1e-07 3.6e-05 24.4 1.9 1 23 693 715 693 715 0.98
11 20 1e-05 0.0007 20.3 7.7 1 23 721 743 721 743 0.98
12 20 4.3e-05 0.003 18.3 6.8 1 23 749 771 749 771 0.98
13 20 3.4e-05 0.0024 18.6 4.4 1 23 777 799 777 799 0.98
14 20 1.8e-06 0.00012 22.7 5.0 1 23 805 827 805 827 0.97
15 20 1.7e-06 0.00012 22.8 4.1 1 23 833 855 833 855 0.98
16 20 6.3e-07 4.3e-05 24.1 5.8 1 23 861 883 861 883 0.98
17 20 6e-05 0.0041 17.9 7.8 1 23 889 911 889 911 0.97
18 20 5.1e-05 0.0035 18.1 8.5 1 23 917 939 917 939 0.97
19 20 0.0023 0.16 12.9 0.6 1 23 946 968 946 968 0.95
20 20 0.01 0.72 10.9 5.1 1 23 983 1005 983 1005 0.99

Sequence Information

Coding Sequence
ATGAATCCGGAGCATCATAATATGAACACGGGTGGTGGCCAGCCTCCGGGAAGTTCTGAGTCACAGAATCAAAGAGTACAAGCTGCTCAACAACAGCAGCAAAATAATATGCCTGCAACAACATCTGCTACTGATCTACGAGTGAACTCTGTGAACTCAGCAGTGAATGTCGCTTTGTCCAGTGTTGCTAAATATTGGGTGTTTACAAATTTATTTCCGGGCCCCATACCACAAGTGTCTGTATACGGATTACCTGCTGGTGCGAGACTCGAAAATGGAAAACCTGTACAGGATCTTGGTCAAGCCCATGCCAGCATACTCAATGGGGATCCAAATATTATTCTTGGGCATCATGCTGGACAATCCCAGGTAACGGTGTCTGCTGCTGGTGGTCAGCAGATACCAGTCTCACAGATTATAGCCACTCAGTCTGGACAAACACATGAAGCTCTTGTGGCTCACAGTCAACAAGCAGAGTTGGCGGCAGCACAAGGCGCCGGCAACAACGCACAGGTGTCAGTTAGCACAGGCCAGCCTACTCATCAGCAGGTACCCAATAATCGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCACGTGGGACATCATTCACAACAGCATATAATGCAGCAACAGCTCATGGCTGCCGCTCGGCCGGAACACAGCAATCAACAGATTCAACTGACTGTGAGTGAGGATGGTATCGTGACGGTGGTGGAGCCGGGGGGCGGTAAGATGGTCGACAAGGAAGAACTACATGACGCCATCAAGATGCCCACCGACCATGCACTTACTGTTCATCAATTGCAGCAAATAGTTGGACAGCAGGTGATTGACAGCGTTGTGCGAATTGAGCAAGCGACCGGTGAGCCGGCAAACATATTGGTGACGCACAACCCTGACGGTACCACGTCCATAGAGGCGAGCGCCGCGGACCCACTCATAGTCAAAGACGAGAAGAACTCCAAGATTGAGACGGCTCAGTTTGCGATACCTGCGGAAATTAAGGATATTAAAGGGATAGATTTAAAGAGTGTAGGCACAATGGGAATGGAAGGCGCAGTAGTCAAGATCTCAGCCGGTGCTTCCGACCACGATCTCCATGCTATGTACAAAGTCAATGTTGAAGATCTCTCGCAACTATTAGCGTATCATGAAGTGTTTGGGAAGTTGAATTCAGAAGGACAACAGCAAGCTAAGGTAATTAGTGAGGTAGAAGTAGAGGCAGGCACGAGTGCGGGGATGTCAGAAGCAGATTCATCGCCTGGTCAACATTCGTGTGATATTTGCGGAAAAATATTCCAGTTCCGATATCAACTAATTGTTCACAGGCGTTATCACGGCGAAAGTAAACCTTTTACGTGTCAAGTTTGTGGATCAGCTTTCGCAAATCCAGTCGAGTTATCGAGGCATGGGAAGTGTCATCTAGCTGGCGATCCGAACGAGAGGCATGCTAAGAGAATGACGCAAGACAAGCCTTATGCCTGTACTACTTGCCATAAAACATTCTCCCGCAAGGAACACTTAGATAATCATGTTCGAAGTCACACAGGAGAAACGCCATACAGATGCGAGTTCTGTGCAAAAACGTTCACTCGTAAGGAGCACATGGTGAACCACGTCCGGAAACATACCGGTGAGACGCCGCATCGCTGCGACATCTGCAAAAAGAGCTTCACAAGAAAAGAACATTTCATGAATCACGTCATGTGGCACACAGGTGAAACGCCGCACCATTGTCAAATTTGCGGCAAGAAGTATACTAGGAAGGAGCATTTAGTGAACCATATGAGATCTCACACAAACGATACTCCATTCCGATGTGAACTGTGCGGCAAGTCGTTTACGAGAAAGGAACACTTCACCAATCACATATTGTGGCATACTGGTGAAACCCCACACCGCTGCGACTTTTGTTCGAAGACATTCACACGTAAAGAGCACCTACTGAACCATGTCCGTCAGCATACGGGCGAGTCTCCTCACCGGTGTAACTTCTGCAGCAAGTCCTTCACGCGACGGGAACACCTCGTCAACCATGTTAGACAACACACGGGAGAAACTCCCTTCCAATGTGGATACTGTCCCAAAGCATTCACAAGGAAAGACCATCTAGTGAACCATGTCCGTCAGCACACAGGAGAATCCCCACACAAGTGTTCGTACTGTACAAAGTCGTTTACACGTAAGGAGCACCTCACGAACCACGTGAGACAGCACACGGGCGAGTCGCCGCATCGCTGTACCTTCTGCGCCAAGTCGTTCACTAGGAAAGAACATCTTACTAACCATATCAGACAGCACACGGGAGAAACGCCACACAAGTGCACGTTCTGTCCGCGCGCCTTCGCCAGAAAGGAACATCTCAACAACCACGTGCGACAGCACACCGGCGTCACGCCGCACTCCTGCTCCTACTGCCCCAAGAGCTTCACCAGGAAGGAGCATCTCGTCAACCATATACGACAACATACGGGCGAGACTCCATTCAAATGCACGTACTGTGCGAAGTCGTTCTCTCGTAAGGAGCATCTAACGAATCACATAAATCTGCACACGGGAGAAACGCCACACAAGTGTCCCTATTGCACCAAAACATTCTCCAGAAAGGAACATTTGACGAATCATGTCAGGATACACACAGGTGAGTCGCCGCATCGATGTGAGTTCTGTCAGAAGACGTTCACGCGTAAGGAACACCTCACGAATCATCTCAAACAACACACCGGCGACACCGCACACTCCTGCAAAGTGTGCTCCAAACATTTCACCAGAAAGGAACATCTTGTCACACACATGAGGTCCCACAGTTGTGGCGAGCGTCCTCACATATGCGGCGAGTGTGGCAAGTCGTTCCCTTTGAAAGGCAATCTGCTGTTCCACGAACGTTCACACAACAAGGCCAACGCCAACAATGCTAACAACGCGAACAGGCCATACAGATGTGAAATTTGCTCCAAGGAGTTTATGTGTAAAGGACATTTGGTGTCACATCGGCGAACACACACAGAAGCGGGTGAAGCTGCGCCCAGCTCTGAAACACCGGCCGAGGGAGAAGATTGTAGCGACTGCAATAAGTGTGTCAAAGCCGAACCTGAACGAATCGAAAGAAAACATGAAATTAGAACATCGGTAGAAGCTAGGCCGACCGAAACTACCGTCGCACAAACTCCGCAGAACACGGCCAACACCGTGATGCAAATCACTAATCAACAAGTGCGTGTGGGCACGTCGGGCGCGGTGGGCGTGGGCGTGAGCGGCGTGGGCGTGGGCGTGGGCGGGGCCGCCGCGGCGCCGGGCACGTTCGCGGCCGGCCCGCACCACGCGCAGCACCCCGTCACCGTTAACTACTAG
Protein Sequence
MNPEHHNMNTGGGQPPGSSESQNQRVQAAQQQQQNNMPATTSATDLRVNSVNSAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGARLENGKPVQDLGQAHASILNGDPNIILGHHAGQSQVTVSAAGGQQIPVSQIIATQSGQTHEALVAHSQQAELAAAQGAGNNAQVSVSTGQPTHQQVPNNRVEFVQHHNIDMVNHVGHHSQQHIMQQQLMAAARPEHSNQQIQLTVSEDGIVTVVEPGGGKMVDKEELHDAIKMPTDHALTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNPDGTTSIEASAADPLIVKDEKNSKIETAQFAIPAEIKDIKGIDLKSVGTMGMEGAVVKISAGASDHDLHAMYKVNVEDLSQLLAYHEVFGKLNSEGQQQAKVISEVEVEAGTSAGMSEADSSPGQHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPNERHAKRMTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQICGKKYTRKEHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSYCTKSFTRKEHLTNHVRQHTGESPHRCTFCAKSFTRKEHLTNHIRQHTGETPHKCTFCPRAFARKEHLNNHVRQHTGVTPHSCSYCPKSFTRKEHLVNHIRQHTGETPFKCTYCAKSFSRKEHLTNHINLHTGETPHKCPYCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKTFTRKEHLTNHLKQHTGDTAHSCKVCSKHFTRKEHLVTHMRSHSCGERPHICGECGKSFPLKGNLLFHERSHNKANANNANNANRPYRCEICSKEFMCKGHLVSHRRTHTEAGEAAPSSETPAEGEDCSDCNKCVKAEPERIERKHEIRTSVEARPTETTVAQTPQNTANTVMQITNQQVRVGTSGAVGVGVSGVGVGVGGAAAAPGTFAAGPHHAQHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
iTF_01333058;
80% Identity
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