Lzep015808.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lasioglossum zephyrum
Gene Symbol
KLHL10
Assembly
GCA_028455615.1
Location
CM052322.1:8977358-8981912[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.6e-28 4.4e-26 91.4 0.1 2 109 40 146 39 147 0.95

Sequence Information

Coding Sequence
ATGGATGTAGACTCGAACGATAACAGCACAGAAATCGACGTATGCGAAACGAGCACACAGCGTTTGATTGCCGAGAGCGGTGGCCGATGTATGAGTACGCAAGCGATGCAATCGCTTTATGACTTTCGACAGAATAATCTTCTTTGCGACGCCGTTCTAAGACTAGAAGATGGAGGCGTTTTCCCTATACACAGAGCGATTTTGTCAGCATGTAGTCCTTACTTCAGGACTTTGTTCACAACTACGTTGCATTTCCGTGAAAAGACTGATGTTCTCCTGCCTGGTGTCAGCAGTAACATGATGAATCTTCTTTTGGAATACGCGTATTTACGATCAATCAACGTGAACAAGGAGAATGTGTGCCAGTTATTGGTGACCGCGGATTATTTGAACATTCTGGGCGTTCTCGAACTCTGCAGCGAGTTCCTTAAACAGAATCTAGCCCCGGAGAACTGTATCTCCGTGATGAGATTCGCGCGGGAACATTTCTGTAAAGGATTGGAGAACAGCGCGTACCGTTACGTTATGAGACACTTCGTACAGGTAGCTCAGCGAAGTGAGGAAATCCTCAATTTACCGATCGAAGAATTGACGACGTTGATTGGCGCTGACGAGTTGAATGTGAAAAATGAGGACACTGTATGGGAGCTGGTGTTGAGGTGGATCGATCACGATCCAGAATCCCGAAAGGGCTACATAGCTGATTTAATGAAGAATATTCGCCTTGGTTTATTGGATACACAATTCTTTCATGAAAACGTCAAGGATCATCCTTACGTTACCGGGAATGTCGCTTGTCGGCCCATCATCATCGAAACGTTGAAATTTATATACGAGCTCGAGATTATCACGCAGAAGGACCGGGAAGTTCCAACGCCGAAAATCGCGAGGCCACGGGTGCCTCACGAGATATTATTTGCCATAGGTGGATGGAGCGGCAGGACTGCTACAAATTTCATAGAGACATATGACACCAGGGCCGATCGATGGGTCAAGGTGGAAGAGGTAGATCCAAGCGGTCCCCGATCGTATCATGGAACAGCAGCAGTTGGTTTTAATATCTATGTGATCGGTGGCTTCGACGGGACCAATTACTTTAACAGTTGTCGTTGTTTCAACGCTGTAACTAAAGTCTGGAGAGAAGTCGCCCCGATGAACGCCAGAAGATGTTACGTCGGCGTTGCTGTTCACAATGATCTCATTTATGCGATGGGAGGATATGACGGGTATTATCGTCAAAATACCGCGGAAAGATACAATTATAAGACTAATCAGTGGTCTTTAATAGCACCGATGAAGTGTCATAGATCAGACGCCAGTGCAACTACATTAAATGATAAAATTTACATTACCGGCGGCTTTAACGGCAACGAATGTCTAAATTCTGCCGAAATGTACGATCCAGAATGCAATCAATGGACCCTCATAGCTACAATGAGATCGCGCAGGAGCGGAGTTTCATGTATCGCTTATCACAACTGCGTATACGCGATCGGAGGGTTTAACGGAATATCTAGAATGTCCAGTGGAGAGAAATATAATCCGACTACGAACACCTGGAGCCCGATTCCGGATATGTATCACGCGCGTAGTAATTTTGGAATCGAAGTGATCGACGACATGATCTTCTCGATCGGAGGATACAACAGTGTTACCACCATCTATCACGTCGAATGTTATGATGAAAAGACGAACGAATGGTACGAAGCAACCGACATGAACATATATCGTTCGGCAGTTTCAGCCTGCGTAATCGTGGGTTTGCCAAACGTAAATGATTACATTCACCAGCACCGTGAGCGCCTAATGGAAGAGAAACGACAGAAATTGCTGGCGCTAGAAGTGCCCCGCAGTCAACAGCAAAATCAGCAGGATCAGGCGCAACAAAATCGCGAGAATTTATTAGTCGATGAAATTATACCAGCGCCGCCACCCATGCCACGAAATAATAACTCGAACAATGAAAATCAACGCAATTAA
Protein Sequence
MDVDSNDNSTEIDVCETSTQRLIAESGGRCMSTQAMQSLYDFRQNNLLCDAVLRLEDGGVFPIHRAILSACSPYFRTLFTTTLHFREKTDVLLPGVSSNMMNLLLEYAYLRSINVNKENVCQLLVTADYLNILGVLELCSEFLKQNLAPENCISVMRFAREHFCKGLENSAYRYVMRHFVQVAQRSEEILNLPIEELTTLIGADELNVKNEDTVWELVLRWIDHDPESRKGYIADLMKNIRLGLLDTQFFHENVKDHPYVTGNVACRPIIIETLKFIYELEIITQKDREVPTPKIARPRVPHEILFAIGGWSGRTATNFIETYDTRADRWVKVEEVDPSGPRSYHGTAAVGFNIYVIGGFDGTNYFNSCRCFNAVTKVWREVAPMNARRCYVGVAVHNDLIYAMGGYDGYYRQNTAERYNYKTNQWSLIAPMKCHRSDASATTLNDKIYITGGFNGNECLNSAEMYDPECNQWTLIATMRSRRSGVSCIAYHNCVYAIGGFNGISRMSSGEKYNPTTNTWSPIPDMYHARSNFGIEVIDDMIFSIGGYNSVTTIYHVECYDEKTNEWYEATDMNIYRSAVSACVIVGLPNVNDYIHQHRERLMEEKRQKLLALEVPRSQQQNQQDQAQQNRENLLVDEIIPAPPPMPRNNNSNNENQRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00860486; iTF_00862664; iTF_00865417; iTF_00861259; iTF_00762640; iTF_01071123; iTF_00763316; iTF_00866100; iTF_00864730; iTF_00863356; iTF_00861981; iTF_00864062; iTF_00024704; iTF_00734026; iTF_00227361; iTF_01068386; iTF_00219203; iTF_00140676; iTF_00216484; iTF_00233316; iTF_00221989; iTF_00230117; iTF_00761061; iTF_00088134; iTF_00221350; iTF_00232070; iTF_00962598; iTF_00982374; iTF_00215111; iTF_01122536; iTF_00086409; iTF_00217161; iTF_00217833; iTF_01069065; iTF_00983050; iTF_01123146; iTF_00231404; iTF_00232684; iTF_00214477; iTF_00225325; iTF_00360301; iTF_00219886; iTF_01066350; iTF_00676111; iTF_01169263; iTF_00084656; iTF_00142544; iTF_00230768; iTF_00963281; iTF_01424465; iTF_01539697; iTF_00215794; iTF_00218514; iTF_00223282; iTF_00118099; iTF_00141299; iTF_00226003; iTF_00222612; iTF_00964564; iTF_01067700; iTF_01070452; iTF_01067030; iTF_00087288; iTF_00141912; iTF_00228056; iTF_00684248; iTF_00873880; iTF_00963928; iTF_00228761; iTF_00983706; iTF_00961915; iTF_00085500; iTF_00226684; iTF_00229437; iTF_01065661; iTF_00088926; iTF_00220670; iTF_00223966; iTF_01069758; iTF_00360991; iTF_01417791; iTF_00224640; iTF_01418432; iTF_00306369; iTF_00966102; iTF_00183365; iTF_00625587; iTF_00184023; iTF_00393688; iTF_01255787; iTF_00773914;
90% Identity
iTF_00183365; iTF_00860486; iTF_00862664; iTF_00865417; iTF_00861259; iTF_00762640; iTF_00763316; iTF_00866100; iTF_00966102; iTF_00184023; iTF_00864730; iTF_00863356; iTF_00861981; iTF_00864062; iTF_00024704;
80% Identity
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