Lmal004877.1
Basic Information
- Insect
- Lasioglossum malachurum
- Gene Symbol
- Lztr1
- Assembly
- GCA_028455605.1
- Location
- CM052317.1:12140659-12143927[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.2e-13 3.4e-11 43.3 0.1 8 105 361 487 354 492 0.76 2 4 3.9 1.1e+03 -0.2 0.0 76 109 490 523 483 524 0.84 3 4 5.8e-18 1.7e-15 57.2 0.1 9 96 584 671 577 687 0.80 4 4 0.71 2.1e+02 2.2 0.1 76 102 685 711 680 718 0.80
Sequence Information
- Coding Sequence
- ATGAACAACGTTGCGTCTGTAGAGTGCTTGACCCTTGAATTCGGACGTTTTGAAACTGTCCATCGATGGCAGCGAATGTTAGAATGCGACGAGTTTGTTGGTGCCAGGCGTAGCAAACACACTGTTGTAGCGTACAAAGATGCAATCTATGTTTTCGGAGGTGACAACGGCGAGAAAATGTTGAATGATTTGTTGCGATTCGATGTCAAAGAAAAATCCTGGGGTCGAGCACCAGCTGCAGGAGCCCGTCCAGCGCCACGCTATCATCATTCAGCGGTGGTTCATGATTCCTCTATGTTTGTATTCGGTGGTTACACCGGGGACATACATTCTAATTCGAATCTGACCAACAAGAATGACTTGTTCGAATACCAATTCCAAACTTGCCAGTGGATAGAATGGGAATATATTAAGAAACCACCACCACCGGTAGCGAGATCCGCTCATGGGGCTGCAGTGTACGACAACAAGTTATGGATATTTGCTGGCTACGATGGCAATCGGAGATTGAACGACATGTGGACCATATCGTTGCTGCCTGGCGAGCCGAGAGTATGGGAAGAAGTAGTTCAATCGGGTGACTGTCCTCCCACATGTTGTAACTTCCCAGTCGCGGTAGCTCGCGAGTCGATGTTCGTCTTCAGCGGTCAGAGCGGGGCCAAGATCACTAACAGTCTCTTCCAGTTTCATTTCCGAGAGAGACGGTGGACTCGGATCTCAACAGATTTTAAACACATTCTGCGGGGTGTTCCACCGCCGCCGGCACGACGGTATGGTCACACCATGGTCAGCTTCGATCGTCATCTCTATGTGTTCGGCGGTGCGGCCGATTCCACGTTGCCAAACGATCTCCACTGCTTTGATCTTGACACGCAAACTTGGAGCATCATTCTTCCGTCGTCTGACAGTCAAATCCCATCTGGTCGTTTATTCCATGCAGCAGCGGTAATAGGTGAGGCGATGTTCATATTCGGCGGAACAGTCGACAACAACGTCCGGTCCGGTGAAACGTACAGGTTCCAATTTTCTTCCTACCCGAAGTGCACGTTGCACGATGATTTCGGGAGATTGCTGATGGGACGTCTCTTCTGCGACGTTGAGTTCATTGTGGGAGAGTCGGAAACGAGAATACCGGCTCACATAGCCATGGTAGCGGCGAGGTCACAGTTTCTCAGGAATCGCATCAGGCAAGCTCGAGAGAAACGAGAGAAACTGGAGAAGGAGGTCAACGACTCGGATCTGTTAGAGGTAAGGCTTGAGGATGCAGTGCCGGAGGCTTTCGAGATGGTCCTGAACTACATCTACACAGATCGCATTGATCCAACGAGAAAGACCGAGGGTGAATCGAGCAGTTGCGCCGAAGATCCTCCGAGCAATCGAATTGTGCTCCTAATGATGGACGTCTATCGTTTAGCCGACCAGCTCAAAATGGAACGCCTTGAACATTGGTGTGTCTACTACCTCATGTCAACTATAAGTCACGCGAATGTTCTGGAAGCGTTGCATAACGCTGGTCAGTTGCGTCTGATGTTCATCAAGGAGTTCTGCTTGAACTTTGTCATCAAAGAAAGCAACTACAGTCAGATCATCATGAGCAAGGAGTTCGAGACATTGGACCAGCCATTGATGGTGGAGATCATCAGGAGAAGGCAGACAAGTCAGAGAAGGAGCTTCTGCGAGATGTACGATGTTGGCACAGGTACGACATTGGAACAAGACATGGAGGCATTCCTGAAGAGCTTCGGTTCTGAATTCTGTGATGTAAAATTAATGCTGAATGGTACGTCCATTCCTGCCCACAAAGCAATCCTTGCCGCAAGGTGCAGTTACTTCGAGGGCTTGTTCCGTTCCTTTATGCCAGTGAACAAGATGGTGAACATGGAAATAGGCAAAATGATCCCCTCCTCCGAATCTTTCAACTCCCTCATGAGGTACATCTACTACGCGGACGTTTCTATGCCGCCGGAAGACTCTGTTTACTTATTCACCGCACAAATTTTCTACGGTTTCACGAACAACCGACTGCAGGCCTTTTGCAAGCAGAATCTCGAGATGAACATTAGCTTCAAGAACGTGATTCAGATCTTGGAGGCTGCTGATAGGATGCAAGCCATTGATGTTAAAAAGTACGTGCTGGATCTCATAGTGCACCACTTCACAGAGGTTGCAAGGCTTCCGGAATTAAAACAATTGAGTAAAGAACTATTGTTGGACATTCTCGAGGCATTAGCTGATGAACGTTGCGAGGTACGAACCTGTCTGGATCTGATGAACGAGTGCAATTAA
- Protein Sequence
- MNNVASVECLTLEFGRFETVHRWQRMLECDEFVGARRSKHTVVAYKDAIYVFGGDNGEKMLNDLLRFDVKEKSWGRAPAAGARPAPRYHHSAVVHDSSMFVFGGYTGDIHSNSNLTNKNDLFEYQFQTCQWIEWEYIKKPPPPVARSAHGAAVYDNKLWIFAGYDGNRRLNDMWTISLLPGEPRVWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFRERRWTRISTDFKHILRGVPPPPARRYGHTMVSFDRHLYVFGGAADSTLPNDLHCFDLDTQTWSIILPSSDSQIPSGRLFHAAAVIGEAMFIFGGTVDNNVRSGETYRFQFSSYPKCTLHDDFGRLLMGRLFCDVEFIVGESETRIPAHIAMVAARSQFLRNRIRQAREKREKLEKEVNDSDLLEVRLEDAVPEAFEMVLNYIYTDRIDPTRKTEGESSSCAEDPPSNRIVLLMMDVYRLADQLKMERLEHWCVYYLMSTISHANVLEALHNAGQLRLMFIKEFCLNFVIKESNYSQIIMSKEFETLDQPLMVEIIRRRQTSQRRSFCEMYDVGTGTTLEQDMEAFLKSFGSEFCDVKLMLNGTSIPAHKAILAARCSYFEGLFRSFMPVNKMVNMEIGKMIPSSESFNSLMRYIYYADVSMPPEDSVYLFTAQIFYGFTNNRLQAFCKQNLEMNISFKNVIQILEAADRMQAIDVKKYVLDLIVHHFTEVARLPELKQLSKELLLDILEALADERCEVRTCLDLMNECN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00087267;
- 90% Identity
- iTF_00866086;
- 80% Identity
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