Basic Information

Gene Symbol
Trl
Assembly
GCA_028455805.1
Location
CM052202.1:9932481-9934078[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 5.5e-18 3.7e-14 52.7 0.1 21 49 2 30 1 33 0.96
2 2 1.4 9.7e+03 -3.0 0.0 2 12 65 75 64 79 0.62

Sequence Information

Coding Sequence
ATGTCCGATCAGCCAGCGCCTTGTCCACTGTGCGGTGCAATTATACGCCAGTCACGAAATCTGAGAAGACATTTAGAACTTCTCCACTTTGGTTTCGGTAGCAACGGTAAATCCAGTGTCCACGCCAGACACCGAAGGACCAGCAGAACAAACGATCTCGTACGATCCACGTTAGCGTTTATTTGTCCGCCGCACATCACGAGGACCGATCATCCAAGAACTATTGAGAACAATGACTTCTCGACGTCTCTTTCCATTGCTTCGACGCTCGCTTCCAATGTTTCAGGAGGTTTGGCGGGACCAAGTTCGAACTCAGTCGCAACCGGAGATCAAGGTACGAGTTCTGCGCTACTTCCAGGCCCAAGCTCGTCCGCCACTTCCACCACTTCTGTTAATAGCGGGATATACGCATATTCGTCGGACAGTAATGTCAATACGTTGAATTGTGTGTCACCTCCGACATCGTCTCTGCCACCATCGACCCTTTCCTCTCCACACGACATGCTCCGATACGGTGAAATTTTGAGAGCTGGTATTGCGTACCACGAATTCTCGAGATAG
Protein Sequence
MSDQPAPCPLCGAIIRQSRNLRRHLELLHFGFGSNGKSSVHARHRRTSRTNDLVRSTLAFICPPHITRTDHPRTIENNDFSTSLSIASTLASNVSGGLAGPSSNSVATGDQGTSSALLPGPSSSATSTTSVNSGIYAYSSDSNVNTLNCVSPPTSSLPPSTLSSPHDMLRYGEILRAGIAYHEFSR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00183630;
90% Identity
iTF_00762917;
80% Identity
-