Basic Information

Insect: Lasioglossum figueresi
Gene Symbol: topi
Assembly: GCA_028455805.1
Location: CM052192.1:2903339-2907978[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.053 4.9 8.0 2.4 1 23 367 389 367 389 0.97

2 14 0.00073 0.068 13.8 0.9 2 23 427 448 426 448 0.98

3 14 0.002 0.19 12.5 1.2 1 23 576 598 576 598 0.95

4 14 0.0044 0.41 11.4 0.3 2 23 602 623 601 623 0.96

5 14 9.8e-05 0.0091 16.6 2.8 1 23 713 735 713 735 0.97

6 14 0.00021 0.019 15.6 0.5 1 21 741 761 741 765 0.92

7 14 0.001 0.093 13.4 3.4 2 23 845 866 844 866 0.96

8 14 0.0003 0.028 15.0 4.4 1 23 945 967 945 967 0.96

9 14 0.00027 0.025 15.2 0.7 1 20 972 991 972 993 0.94

10 14 0.04 3.7 8.4 0.5 2 23 1004 1025 1004 1025 0.97

11 14 2.7e-05 0.0026 18.3 0.6 2 23 1064 1085 1063 1085 0.97

12 14 2.5e-05 0.0023 18.5 1.6 1 23 1090 1112 1090 1112 0.95

13 14 0.00014 0.013 16.1 2.9 1 23 1118 1140 1118 1140 0.98

14 14 4.4e-06 0.00041 20.8 0.4 1 23 1156 1178 1156 1178 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.053	4.9	8.0	2.4	1	23	367	389	367	389	0.97
2	14	0.00073	0.068	13.8	0.9	2	23	427	448	426	448	0.98
3	14	0.002	0.19	12.5	1.2	1	23	576	598	576	598	0.95
4	14	0.0044	0.41	11.4	0.3	2	23	602	623	601	623	0.96
5	14	9.8e-05	0.0091	16.6	2.8	1	23	713	735	713	735	0.97
6	14	0.00021	0.019	15.6	0.5	1	21	741	761	741	765	0.92
7	14	0.001	0.093	13.4	3.4	2	23	845	866	844	866	0.96
8	14	0.0003	0.028	15.0	4.4	1	23	945	967	945	967	0.96
9	14	0.00027	0.025	15.2	0.7	1	20	972	991	972	993	0.94
10	14	0.04	3.7	8.4	0.5	2	23	1004	1025	1004	1025	0.97
11	14	2.7e-05	0.0026	18.3	0.6	2	23	1064	1085	1063	1085	0.97
12	14	2.5e-05	0.0023	18.5	1.6	1	23	1090	1112	1090	1112	0.95
13	14	0.00014	0.013	16.1	2.9	1	23	1118	1140	1118	1140	0.98
14	14	4.4e-06	0.00041	20.8	0.4	1	23	1156	1178	1156	1178	0.95

Sequence Information

Coding Sequence: ATGGACGCCGTAGGAATAAATACGTCCGATTCGACGCAAAATGAGGAGGAAAGCATCGTGTCGACGGTGGAAATATGTCGTGTTTGTCTTCTGGGTAATCTAGTGATGCGGGACTTGTTTCTAGAGAACGAGGTTTCTTCTCTATCGGCGAAAGCGATGAGTTTTACAAACGTTAAGATGTTACCCGACGATGGATTGCCAACGCGAGTATGTTGTATGTGCGCGGATAAACTTGAATCCGCGTACGAATTCAAGCTACAGGTGGAACAAGCAGACACGGTTCTAAGAGAGAAGTTTGTCACGATGAACATGAAGGAGGAATTATTTTTTAACGAAGTCGAAGTACACCTGGAGGTAGGAGAGAGAAACGAGGACATAGAACGGATGCACATAGAGAATCATTATCAAAACACGGTAGAAACATTGGAAACAATGTCCGGAGATGAAAAGTCGTCCCTTTTGAAGGATCAGTTGGCTTTGTTGCAAGTGGGGAAGTTGGCTGAACAGGAACAGACGATAACCGAACAGCACGATAGTACGGTGATGGAAGAAGGGATCGTGTCGGAACAGATGTTGGTCGAGTGTTCCAATAGAGAGGAAGATAACGGTAAGGCTATGGACATTATAACCAAGGACGAAATAATCCTGAAACACGAGAATATATCGACGGTAGAGCACGATTACATATTGCAACAAGACTGCATACTGGAAAATGATAGTCAGCGAAAAGAAGGAACAGGGGAACAAGAGGAAGAACGAGAAGAGCAGCAGTTGATATCGGAAGAATCATTTTCGCGGGACGATTGCGTACAGTATGTGAATATGTTGGTGAAAGCAGCCAACGTGACTCATAGAGAAGACGGAGAGGACGAAGATCCGAGCGAAAACGAGCAGCCCGATGAAGAGGGTTCGAGAACAAATGCAAAGCTGGAAGAGGATTCTCAGTGTCAAAGCGAGACGAGAAGAAGCAAACGTAAGCAACTTCAAAGTAGCACCGACCCCATGCGAGACTCCGACGAGGAAAATTATTTTGAAAACTTAAATCTAAGTTCGCGACTGAAGAAAGCCGAGGACTCCGAAAAGTCGGAAAGAATCTTTTTCATGTGTTACCTTTGCGACAAAGAGTTTTTATCGAAAAACGTTTTGCGGGAGCATATGCATTCTCACGAGGAAGTCCGAGAGGTATTGTCGTTGCGAAAATCCGTGGAGAAGCCAGAGAAAGACGTCGAAAGATGCAATAATGTCACGAAATTACCTCCATCTGGTAAAAGATCGAACAAATGCCCGTACTGCGGTAAACAATATATATACATAATATCGTTCAGCAAACATTTGAAGAAGCACGAGAAAGAGAAAGAAGAGGCGAAAGAGGAATCGTTGCCGTTGGAAATTTCGTTTCACGAAGACGAGCACAGTTTGGATTTCGAGGATTTTGCGGATAAAGATAACATGAATTCGGAGTACCGAAAAAGAGTCAGGAAAAGAGAAGGCGTGGCTGTAACAAAATCGGAGAAAGAGGAACCAATGATAGAGCAGACGGAGGAAGAGCAACAGGAAGGGGAGGAAGAAGCCTTAGACGAAGAAAAAGAGGAGTTCGAGGGAACCGAATGCGAGGAGAAAGCGAAACGGAAAGAGAAAGAGACAAGCAGCGGGGGTAAAGAAAGGATCTGTAATCGAAACGAAAATGGGGAACGAAAGAAACGCGAAGCACGCGTGGAATCGTCTTTCGCGTGCGACAAGTGTCTAGAAAAATTCTCTACAAGACGAGGTTTGCGGAAACATTCGATTTCGCATGCTGCTCTCAGATGTAGCGTGTGTGAAGAAGAATTCGACTCGTTGGTGAAGCTGAGAAACCATCGGGCAAAGCATGTTGTTGAAGGTGTATTGTCGGAACAAGATCTGGAAACTGGTACTGAGTTTCCACTTGACAGGGACAAGGATGGCTGTCGGGTTGTTGTGGACAAACGGAAAGAAGAAGAACAGGTACAAGGACCTCACGAAGGAAGAAGGCGGAAAGAAAAGGATGTACGGGAACGAGAACGAGAACGAGAACGAGAAGGAGAACCCCAGACACAATCGTCGGAGAACGTGTTGAAAAGAAGCGCAAGAAACACGGAGATGCATTCGGAGGTCGAGTTCAGTTGTAAGGTATGCCATCAGCGATACACGAGAATAGATTTGTTGCAAAGGCATATGGAGCAACACGAGCGTGTTAAAAATTACAAATGTACAGAATGCAATAAAACGTTCGGTAATGAACTGACTTTACGAAATCATCTTATAGCTACGAATCACAAAACTTTTGTCCGAGGACAAGAGTACGATCCAAACAAACGGATCAAACGTGTGGCTGCAAGAGCAGCTCAGAAAATAATTGATAAAATTAAGACGGAAGATGGCCTGGAAGATTACGAGGACGAGGATGAACGGGAAGAGAAGATAGCCGAGCGGAACTCCACGGACGGAAATTACGGACGGAACAAGCGTGAGATTTTGTCTCCGAAGAAACACAATTTCTCGAAAAAGGAGCTGGAATGCACGAGCTGTAACAAAAAGTGTAGCTCGAAACAGTCGCTAGCGAAACACATGGAACAACACGTGAAGGAGGAGAAAACTGTCAAGTTGGAGAGGGAGAGGGAGAGAGAAAGAGAGAAAGAACGAGAGAGAGAGAGGGAGAAAGAAAGGCAAAGACAAAGGCAGGGCACCTTCGGGGACAAGAGAGAACGACAGAGGAGCTGCGTGAACAACGACGCGGTTGAATCGAGCGAGGTCAACAAGGACGATGACTACGATTCAGATTTCGAAAGCGGGTTGGATTGGCCGATGGACAATCACGAATGCGTAAAGTGCAAGAAACGATACAGCACAAAGAAATCGTTGCTGCGCCATCAACTTTTGCACGAGGAACCGAACTTCGAATGCGACATTTGCAACGTGAAATTCTATCGTAAAGACAAGCTGAAAGCTCACTACGACAAGTGCTCGGAAAAGAACCCTGACCAGGTGAGAAAATGCAACATCTGCGGGGACAGTTTCGAAAATAACGAGATATTGCGAGAGCATAGATCGAAACATGTGACAGAAGGCATTCTCACCGAGGAGGACCTGAGGGATATCGAGCCGCGGCCAGAAGAGAAGAAGCCGGGAGAGAAGATCGGTAGGAAAAGAAGGACCGATATAGTGGGATTGGAGTGTACCGAATGCAACAAACAGTACACCTCTAGGAAAGGGCTACTGCGTCACATTCAGGTTCACGAAGGGAAGAAGTACCTTTGCGACATATGCCCGAAAAAGTTCTACAGAAGAGAACATTTGAAGATACACGTGGCCAAGCATAACATGATCAAACCGTACAAGTGTACGCGCTGTACGAAACGTTTCATCAAAGAAGAACAACTGACCAATCATTTGTCGAAACATGATCGAACATTTAAGAAGAATAAAGAAACTGATAGCTCCAAAAGATTTCTTtgcgagatttgctcgaaaagtttcacccaatcgacgacgttgatcgcgcacctcagagctcacaacggcattaaaccgtatgtttgtgagAATCGTGGCCAAACGTTGACGCAAGTACAATCTTCCCAGAATCAGCAAAGAATATTGCATCAGCAAACCACTCTTGGACAGACGCAACTGTTGAAAGCGCAGAACATTAAAACTATTACGATCACTAGACAACCAGATGCCGTTGCTGCCCAACACGTCGCGCAGCATCAAGAAATAATAATGCCCCTGATCTTTCCTTTAACCGTCACAGTCGCCGATATCAGCGAAGAAGTTATATTACCGGAAGGAACCAAATTGTTTACGACCACTTAA
Protein Sequence: MDAVGINTSDSTQNEEESIVSTVEICRVCLLGNLVMRDLFLENEVSSLSAKAMSFTNVKMLPDDGLPTRVCCMCADKLESAYEFKLQVEQADTVLREKFVTMNMKEELFFNEVEVHLEVGERNEDIERMHIENHYQNTVETLETMSGDEKSSLLKDQLALLQVGKLAEQEQTITEQHDSTVMEEGIVSEQMLVECSNREEDNGKAMDIITKDEIILKHENISTVEHDYILQQDCILENDSQRKEGTGEQEEEREEQQLISEESFSRDDCVQYVNMLVKAANVTHREDGEDEDPSENEQPDEEGSRTNAKLEEDSQCQSETRRSKRKQLQSSTDPMRDSDEENYFENLNLSSRLKKAEDSEKSERIFFMCYLCDKEFLSKNVLREHMHSHEEVREVLSLRKSVEKPEKDVERCNNVTKLPPSGKRSNKCPYCGKQYIYIISFSKHLKKHEKEKEEAKEESLPLEISFHEDEHSLDFEDFADKDNMNSEYRKRVRKREGVAVTKSEKEEPMIEQTEEEQQEGEEEALDEEKEEFEGTECEEKAKRKEKETSSGGKERICNRNENGERKKREARVESSFACDKCLEKFSTRRGLRKHSISHAALRCSVCEEEFDSLVKLRNHRAKHVVEGVLSEQDLETGTEFPLDRDKDGCRVVVDKRKEEEQVQGPHEGRRRKEKDVREREREREREGEPQTQSSENVLKRSARNTEMHSEVEFSCKVCHQRYTRIDLLQRHMEQHERVKNYKCTECNKTFGNELTLRNHLIATNHKTFVRGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDYEDEDEREEKIAERNSTDGNYGRNKREILSPKKHNFSKKELECTSCNKKCSSKQSLAKHMEQHVKEEKTVKLEREREREREKEREREREKERQRQRQGTFGDKRERQRSCVNNDAVESSEVNKDDDYDSDFESGLDWPMDNHECVKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRSKHVTEGILTEEDLRDIEPRPEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCENRGQTLTQVQSSQNQQRILHQQTTLGQTQLLKAQNIKTITITRQPDAVAAQHVAQHQEIIMPLIFPLTVTVADISEEVILPEGTKLFTTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00865472;
90% Identity: -
80% Identity: -