Basic Information

Insect: Lampropteryx suffumata
Gene Symbol: baz-2
Assembly: GCA_948098915.1
Location: OX402573.1:5503446-5540665[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 9.1e-11 5.2e-07 30.1 0.0 3 74 647 721 645 724 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	9.1e-11	5.2e-07	30.1	0.0	3	74	647	721	645	724	0.86

Sequence Information

Coding Sequence: ATGGACAAGGAGAGCGGCGATGCTGCCGACTCGGCGGGAAAGACACCCGATGGCCTGTCAGCCCTCGACGCCGCTGGCCTCTTTAATGCCTACTATGGCATGGGACGAGACGGGTCGGGGGCGGGGGGCGCGGCGGCGCAAGCGCAGGCGCAGGCCCAAGCTGCGCTATTCGGGTTTGGATCCCGCTATCCTCCGTCTTCCACGCTCGGGGTGGCTGCCAACCAAGCCGCCTCACTAGGACTGCATCCCGCTGCTAGTGCAGCATGGTGGTCAATGGCAGCGTCTCACATCGCTGCTCAGGATTATTTAGCGCGTATTCAGACTGCAGGGCTCCAGGGCTTCCCCCCTATGGGGGACCCCTATTCTACTCTCTCTGCCCTCTCCGCTGCTGGTATGAAGCATCCGCAGAAACCGAGCAAACCCGCCGGCAGGAACGAAAGATCTGGCAGAAGCAGTACATCATCCAGTGCTTCCACCAAGGATAAGAGTCCGTCTACCAGTAACGCTAACTCTCAGCCGAATCTTAGCGACTGGGCGTCTACATACGGCTTCCCGAAGACATCTTCCCCATCCACGATGCATTCGCAGTCGCTGTCCAGTCTCGCATCGTTAAACAGTCTTGTGTCAAGTCCGCATCAAAGCAAGAGTAACAAACAGCAACCACCTTCGCAGCCAAGAAAACAATCTTCATCGTCAACATCATCCACATCGTCGAAGAGCAAAGAGCGCGAACTGGCGTTACTTCGCGGTGATCTGATGTTAGCGCAGGCTGCGGCTCACGGGGCTTACCACGCAGCCGTCGCACACGCTGCCAAGGGAAAGAATATCCAAAACATGTCATCTCTATACCCTTTTGGGATGCCAGGATCTGAAAAGGACAGACATGGTGGCATCGACGCATTAACTGGACTACCCCACACTATACTAAGTGCCGCTTTGGAAGGAGGTGACCCAGCTTCTGTGTTAGGAGGAGTGAGACTTCCGCCAGATACTGAAATCATTAAGTATACATCTGCATTGGCGGGGCCGAAGGTACCACCGGGGACTACGAATAGGGGTAGGAAGAAGACGATATCCCTGGACCCTCCCCAAGTATCAGTTCACCCGAGCGCGTCGGACGGGCGGGGCACGCCTCTGCCGACCAAACGGCAGAAAGTGCATAGAAATGATGATTACGGCGCGCGTTCAGCTGTCGAGGTGATCCGGTTGCCGAACAAGCCGGACCGGCCTGCCAGCGTGGCGGGGACACCGCCACCCAATCTCGCAGACTATGCCGGTATATCCCGCGAGCTGCTGCAAACGATAGCTAGTCAGAGCGGCGTCAGTTTGGCCGCACTGGAGCGTCAGTTGGCAGGTTCCGCGACCAACAGGAGTAAAGATTCTGGTCTGAACCTGTCGAAGTCTAACGCGAGTTCAGAAGACTGTCCACTCGATCTCGGCTTGAAGACTGACGAAGATGCTCCCTTGAACCTCTCCCTCAAGCCTACACCACCGGCGAGCCAGGCGTCTGACGCGTTGTCTAGACTAACGTCATTGAGTAGTTCGCTCAACGCATCTTCACAGAACGACCGAACTTCTCGTCGCAAACCGGGTGGCCGACCGCGTCGGGTGGTTCCAGAGTTGAATACAACGGTCGTCGATTCACCTCGACCCCGCTCCAGTGGTAGTGAAGATAGCGAATCGGTTTCAGCGTGGCCATCGCGTGAGGGTAGACCTCGGAACCTCGGCCGCGGAGTCAGCAAACCTAAAAAGAACACCGTCGCTTCCCTCCTAGCGCAGAGCAGGGCTTTGGGACTGAGGCCGGCTTTGGCGCAGCAGCTATTAGGAGAAGCTGATTTGGAAAAGCTGAAGTCAGTGCTGGGTGAAGCGGCGAGTACGAACTCTGAATATTCGTCTGAGAGCCCGTCCGACTCTGACGTCAGCGAGGACAGACGAGACCAGGATGCTCAGCTGAGATTACCACTGGCGTTAGGTTGGAAGCGAGTAACAGTTATCAAAGGGCTATCGAGGAACTGCAATATAAAGGGTGATGTGACGTACGCTCCTCCCGAACCCCACGGTGCCTATAAAATCACTAACGCACAGGACTTGATAACGTTTCTAGATACGAACCCGTGCCCGCCGCTATCGACAGATAACTTCAGTTTCAACGGACGAGTCATACTCGGCGAGTACGTACAGCCACCCCTCGATACTGGACACAACGACCCTCTCATCTTCAACGAAAACGAGATCATGAAACGGTTAGAAGAAGCAAGAGCCTTGGCAGCTTTAACAGGTCCTAGACCGACACCGCCACCTGTCGACAGACGGATCGAACTAGCGAGAAGGCAACAGGCGGCCAGAGATGCGAGAAGGGACGCTAGCAATAGATCTAGAGACCAGGCTCGCTTAGTTCGTGAACTGGAGCGTTCCGAAAAAGCAGAGATGGTCAAACGTGAGAAGGAAGTCAGAAGTCAACAACTGCTGGAGCATATCAACAAGAATCGAACACAGCTGACGATTGAGGCTCTGCCGATGCCTAAAGAGCCATTGAAGACAGAACTGTCAAAAGCTGACAGAAAAGAACGTATAATGCCACCTATAAGCCTGTCATTAATTCCCGTGACTGGGCCAAAAGATAACTCTCCTTTGAAAACGTTGAATTTTGAACAAGGGACGTGGAATGAGGAGATCGAAGAGTATAACGCGTTGGATAAAATGAAGGATTTCGCCGAAAAAGCGGCCTTTGATATCCCAAAACGAAAAGGGAAATTCGACTTCTCTATCATAAAACCTGACAAAGGTAGCAATATGGAGAAACTGATAGAATCATACTCCAGAATAAGCGAGTTTATGAACGGCTGCAATTGGTCGAAATCGCCCGAGAAACCTGATTCTAAATCCCTCGAGAAAGACCCCAAGTCATTAGAAAAGAAGTATCTTGATGCTAAAAACGAGTTTATGTCGGAGAATCTTATGCTGATGCCTAAAAAGGTTGAGTTAGAAACGAAAGAAGATCCCAAAGTTGCTTCAGGGGAGGTTATTGACCTTAGCGAGGGTGAAGAGACTGATATAACAGATATAATAAGAAGGAAGTTGCAAAAAGGTTCGGTTAATGTCGGAAAAGACGGAGCGCTTTCTATTTCTGTTCAGCAAAGTAAAGAGTACGGTTCGGTACGTTCAAGATTCGAAATAAAACTCTAA
Protein Sequence: MDKESGDAADSAGKTPDGLSALDAAGLFNAYYGMGRDGSGAGGAAAQAQAQAQAALFGFGSRYPPSSTLGVAANQAASLGLHPAASAAWWSMAASHIAAQDYLARIQTAGLQGFPPMGDPYSTLSALSAAGMKHPQKPSKPAGRNERSGRSSTSSSASTKDKSPSTSNANSQPNLSDWASTYGFPKTSSPSTMHSQSLSSLASLNSLVSSPHQSKSNKQQPPSQPRKQSSSSTSSTSSKSKERELALLRGDLMLAQAAAHGAYHAAVAHAAKGKNIQNMSSLYPFGMPGSEKDRHGGIDALTGLPHTILSAALEGGDPASVLGGVRLPPDTEIIKYTSALAGPKVPPGTTNRGRKKTISLDPPQVSVHPSASDGRGTPLPTKRQKVHRNDDYGARSAVEVIRLPNKPDRPASVAGTPPPNLADYAGISRELLQTIASQSGVSLAALERQLAGSATNRSKDSGLNLSKSNASSEDCPLDLGLKTDEDAPLNLSLKPTPPASQASDALSRLTSLSSSLNASSQNDRTSRRKPGGRPRRVVPELNTTVVDSPRPRSSGSEDSESVSAWPSREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAQQLLGEADLEKLKSVLGEAASTNSEYSSESPSDSDVSEDRRDQDAQLRLPLALGWKRVTVIKGLSRNCNIKGDVTYAPPEPHGAYKITNAQDLITFLDTNPCPPLSTDNFSFNGRVILGEYVQPPLDTGHNDPLIFNENEIMKRLEEARALAALTGPRPTPPPVDRRIELARRQQAARDARRDASNRSRDQARLVRELERSEKAEMVKREKEVRSQQLLEHINKNRTQLTIEALPMPKEPLKTELSKADRKERIMPPISLSLIPVTGPKDNSPLKTLNFEQGTWNEEIEEYNALDKMKDFAEKAAFDIPKRKGKFDFSIIKPDKGSNMEKLIESYSRISEFMNGCNWSKSPEKPDSKSLEKDPKSLEKKYLDAKNEFMSENLMLMPKKVELETKEDPKVASGEVIDLSEGEETDITDIIRRKLQKGSVNVGKDGALSISVQQSKEYGSVRSRFEIKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00119620; iTF_00662245; iTF_00661303; iTF_00638667; iTF_01219795; iTF_01335959; iTF_01528315; iTF_00663101; iTF_01529214; iTF_00737503;
90% Identity: iTF_00119620;
80% Identity: -