Lhir003229.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lagria hirta
Gene Symbol
Hr39
Assembly
GCA_947359425.1
Location
OX375803.1:10231356-10237328[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.04 4e+02 0.9 4.1 45 129 191 279 162 323 0.68
2 4 3.2e-08 0.00032 20.9 0.0 1 24 382 405 382 420 0.86
3 4 0.39 3.9e+03 -2.4 0.0 93 119 450 473 403 485 0.67
4 4 1.3e-73 1.3e-69 236.4 0.1 205 408 514 712 493 712 0.96

Sequence Information

Coding Sequence
ATGGCCGCCGACATGAGGTCACCGAACGTATCCGTAACTCCAATTAACATGGAGCCCCCCTATCCTGCTAACTGTGATCTTTTACCTGAGGGGGAGCCTCAACGTACTCGAAGTGCCCCCCATCCATCACTTTCTGTTTCGACAAATGGTGATATACTCGATAGTTCGGATGCTGAAGTAGCCCGAATTGATTTTCACAGTGTTAATATGCGACATAAAAAGAAACGTGATGGGGGTGGAGATATACCTAGACCTATGTCATGGGAGGGGGAATTAAGCGATCATGAAAGGGATATGTGTGTGGATGATCCACAGATACCGGAAAACCTTTCTTTATCTCAGCCGAAATTAAACACCTTATCCAATTTGGATTCAAAAGGAAGTCCTATTTTACGATTAAAACAACAACCTCCAATTGGTACCTATTCACTACACAGCACCCCTAGTAATTCACCACTATTGGGTCGAGTACCAATGATGGGACATAAAGATCTAATGCATAAAGCTCTTAACGTTCCACCAACACCAAGTCCCGATTCAGCCATACATTCAGCATATAGTGTTTTTAGTTCGCCAAATCAAAGTCCTTTAACGCAACGACATATAACATTAACACCGAATTTAAGTCGAAATAACAGTGATGCTTCACATTCAAGTTGCTGTAGTTATTCAAGTGTTTCGGTGTCAGTGTCGCCAACGCAACAATTTTCGCCTACACATAGCCCTATTCAGAGTCGGCATATGCACAATATTCACAATAGTCCTCTTCATCACAACGTTCTGTATCGAAGTCTTCAAGAAAGCGATTCTTCATCTGCTTTACAGTATCCCGATCACGATCAGCTCGTGGATGAAACCGAAGACAAATCAGGACTTGTACATACTTCACTTCCTGCACAACCCGGCATCTCTCGACAACAATTAATCAACAGTCCTTGTCCAATTTGTGGCGATAAAATTTCTGGCTTCCATTATGGAATATTTAGTTGTGAATCTTGTAAAGGTTTTTTTAAGCGTACCGTACAAAATCGAAAAAATTATGTTTGTCTACGTGGTGCTGCATGTCCTGTTACTGTTGCGACACGAAAAAAGTGTCCGGCGTGCCGTTTCGATAAGTGTTTGCAGTGTGGGATGAAATTGGAGGCGATAAGAGAAGATCGTACGAGAGGTGGTCGTTCAACGTACCAATGTTCGTATTCTTTACCACCATCACTAACGAATCATTCGGAATTAAGAGCAAGTTCAAACGATTTAAGGCAAGGAATGGGGGATACACATCATGGTTTAACAGTCAAGTTGGAGCCATCTGAAGGAGGGAGTTGCCATAAGAGGAGCGGCGGGGCGTTGCCGGGGTCAAGAGGTGTCCCAGCATTATTGCAAGAAATAATGGATGTGGAGCACTTGTGGCACTACAACGAAATGGAGTTACATAAATTAAGCACAGAAGGTCATTTGGGTAGAGAAGGTGGTAGTGGAGCCGTCCATAATTTGTCAAATCATCCTTTATTGGCTGGTACAGCTTTAGCAGGTTCAACAGATACCAATCCTGATTTTGTAGCAAATTTGTGCAATATAGCTGATCGAAGACTGTATAAAATTGTAAAATGGTGCAAAAGTCTCCCATTATTTAAAAACATATCGATTGATGATCAAATATGTCTTTTAATCAATTCCTGGTGCGAATTATTGTTATTTTCGTGTTGTTTTCGTTCGATGTCGACGCCAGGCGAAATTCGTGTTTCTTTAGGAAAAAGTATCACATTGGCGCAGGCGAGGGAAATGGGTATGCAAGCGTGTATTGAACGAATGTTGAATTTTACGGAACAATTGAGAAGATTAAGGGTTGATCAATATGAGTATGTTGCCATGAAAGTTATAGTTTTATTAACATCAGATACATCAGAACTACGAGAAGCTGAAAAAGTGAGAGCGTCACAAGAAAAAGCATTAAAAGCGTTGCAAGATTACACTTTAAGTCATTATCCCGATAGTCCTGCCAAATTTGGAGAATTACTACTCCGCATTCCTGAATTGCAACGAACTTGCCAGGTTGGAAAGGAGATGTTAACGATTAAATCGAAAGACGGCGACGGCCCGAGTTTCAATCTCCTAATGGAGCTCCTTCGTGGGGATCACTGA
Protein Sequence
MAADMRSPNVSVTPINMEPPYPANCDLLPEGEPQRTRSAPHPSLSVSTNGDILDSSDAEVARIDFHSVNMRHKKKRDGGGDIPRPMSWEGELSDHERDMCVDDPQIPENLSLSQPKLNTLSNLDSKGSPILRLKQQPPIGTYSLHSTPSNSPLLGRVPMMGHKDLMHKALNVPPTPSPDSAIHSAYSVFSSPNQSPLTQRHITLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQSRHMHNIHNSPLHHNVLYRSLQESDSSSALQYPDHDQLVDETEDKSGLVHTSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHSELRASSNDLRQGMGDTHHGLTVKLEPSEGGSCHKRSGGALPGSRGVPALLQEIMDVEHLWHYNEMELHKLSTEGHLGREGGSGAVHNLSNHPLLAGTALAGSTDTNPDFVANLCNIADRRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLAQAREMGMQACIERMLNFTEQLRRLRVDQYEYVAMKVIVLLTSDTSELREAEKVRASQEKALKALQDYTLSHYPDSPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00753059;
90% Identity
iTF_00852711;
80% Identity
iTF_00852711;