Basic Information

Insect: Lagria hirta
Gene Symbol: egg
Assembly: GCA_947359425.1
Location: OX375802.1:3634982-3640505[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.4e-14 2.8e-10 40.4 0.0 4 74 698 761 695 764 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.4e-14	2.8e-10	40.4	0.0	4	74	698	761	695	764	0.89

Sequence Information

Coding Sequence: ATGGAAGAAGACGACATGGACATGGAAATTGATGATACAATTTCTAACCACAACGCCACAATAATCGTGCGGGAAGCAACAGGAGTGCAAATAATTGGGGGCCCCGCCGCTGATTTATCGACGAGCACATCTACATCGACGCCATCAACTCCATCGAAAATGGAAGAGTCTCAGGTAAAACTTGAAAAAAAACCGGCTTCGAAACCAGCAGATATTGTAGTGTTAGATGACGACGAAGAACCGGCTCCTCCGAAAAGTTTAGAAAAGAAATCATCTGGAGACGACCAAGTTGAAATTATTGATTTGGTAGAAGAAAAATCGATTAGCAGTAAATGTATTAATTATTCTTGTGCTAGTGGGAAGGATTTGATGATAGCTCCAAATATGTGTATGTCTTATTATCGGGTTAAGAATCCGGGAAATGGCAAAAAAGAAGTGTGCGCAGAATGTTTCAACCTCGCTTTGAAAGACTATGATTCATTGGCAACAGAACTTCTTCAAGGGAATATCTTGGGAAAGGTTAAAGTTCCGATTAGGAATGATACTGTAGAAATTGATGATAGCGATGAGGAAGATGTGGAATCAAGAATACCTGAGATGGATAAAGAAGACATTGCTTTGGTAGAGAAAAATTTTGAAAAAATATTAATTGAAACAATGAAGCAATTAAATTTTGATGCACAAGTTAATAAGGAGACAACTTATCTCAAAGAACAGAGTAGTAAATTATGCAAGTCAAGAACTGAGCTACAAGCGATGATTAAAGAAACTAGAAATACTCTCGATAAAATTCAATTAAATTTGTATAATGAATTTAGAAGTGAAACAAGGGAAACGTGTGTCATATCGATTATTGACGATCATTTTGCAGCATCTACTCCTATCATACGAAATGAGTCTGGGCGGTTTCAACAGCCTTCACCAAGAAAGAGCCAAAGAACTGTCACAAAAAAAGTTTCTTACTCAGATATGGAAAATCCCAGTAGTCCTAAAGTTACTTCCAACGAAGAACTTATTGAAGTACCTAAGGACCTACCAGTTCTTGGATCTATTGAACCTCCGGCAATTATTCTAGAGGATTTATATTTTATTTCACGAGAGAATTCATCCGGTTCATGGATTAAGGCACGTCTAAAATCAATTGTATCATCAGGAACTGTAGTAAATGGGGCACCTATAACAACTCCTCATTATAAAATGCTTGAGTTGAAACAACATAAAGAACGTATTGTCAATGGGAAGACTGTTGCATCAATGAAGTCTTCAAAAATTCGTTTAGAGACTGGAACAAGAGTGATTGCTGCTTTTAAAGAAGTGAGTAACACGGGAGAAATTAAAAAGCCGAGACATGATCCATTTTATCCGGGGATAGTTGCAGAACCACCTGTTGCTCAGAATAAATATCGATATTTGATCTTTTTTGATATTGGATACTCACAATATGTGCATTACTCCAGCGTACATGTTGTTTTCGAATATAGTAAAAACGTTTGGGAAGACATGCACGTAGATTCACGTACATTTATTAAAAAATATTTGGAAAGTCCAGACAGACCTATGGTTAAATTATCAAAAGGTCAAACGGTTAAAGTCGAGTATCAAGGTAAATGGTTACTTTGCACTATAATGAATGTTGATTGTTCATTGGCGCTGGTGTTTTTTGATTCTTTGAATCGAACTGAATGGATTTATCGAGGCTCTCCTAGATTAAGTCCTATGTTTAAAGAGGAACAAAACGCTTCAAAGCGACAACTTGGAGGACGACCTTCTAATCGAAAACCAGGATCTGAATCTATGGTGCAGTATACGAAGAACGCTGACTTTGATAAACCAGAAAATGAGGCAGCAGCACCTGTACGAGCCGTGGCTCGTAAAAGTACTGCACGACCCGAAAATAGCACTGCACGATCAGGTGGATTCGTGCCATTTTTACCACCTGTTAGTAATAATGTAGTGCATATGGAACCTACCAGCAAAATTATGTACTTTACTCCTCGTGACCAAGTTATCACTCAAAGAATATATCGCACTCATAATTGCTCGCCAGCCTGTAAAGACTACATAAGACACAATTTAAGTAAACTACGAGGACATAATCCTCTTTCTAAACCGCTATTATGCGGTTGGGCTCGAATAACCCAAAAAGTGAAAGGTAGAAAAGAAATTCTTTATAAAGCACCTTGTGGAAGAATACTGAGAAATATAGTCGAAATTCATAAGTATTTAAGATTAACAAAAAGTGAGATGACTGTAGATTTGTTCGACTTCAACCATATGGTTAGATGTTTAGCTGAATTTAACGTAGAATGTGCACCAGATCCTAAAGATTTATCAAAAGGACTTGAGCAAGTACCAATTCCTGTAATCAATGGGATCAACAATGATATGCTCGATTTCTGTAATTACGCGATTAAAAGAGTACCTATGGAAGACGTTCCACTGAATGTGGATCCAGAATTCTTGATAGGATGTGATTGCACGGATGACTGCCAGGATAAATCAAAATGTTCGTGTTGGCAATTAACTTTGGAAGGTTCTAGATATATGGGTAGAAATGTTGATCCAAATAATATTGGTTACGTTTATCGAAGACTTCACGAACAAGTACTAACAGGAATTTACGAATGTAACTCACGCTGTAAATGCGCTTCAACATGTTTGAATAGAGTGGTTCAGCATCCTATGTCAATAAAATTACAAGTCTTCAGAACTCATAATAGAGGATGGGGTATCAGATGCGTAAATGATGTCCCACAAGGTACATTTATCTGTATTTATGCAGGTACTATCCACACAGAACAAATGGCCAATGAGGACGGCGTTACGTATGGCGATGAATATTTTGCTGAATTAGATTATATAGAAAACTGCGAAAAACACAAAGAAGATTATGAAAGTGATGTTGCAGATCCGGACAGTCCACGAAGTCGCAGTCCTCCATCTCCGGATGAGGATGATGACGACGACGATGACGATGATGGGGGAAGACGAAGAAGAAGACGAGGGAATAAAAAAATATATGATAATGATTTTTGTATCACTTTTCCTCTTTCTCGTTCTGATACATGGGAAAAATCTATGAGTCTAAGAAAACGAACTCAAGAAGAATCGCGAGCCGAAGCAGCAGAAAAAGAGTTGAAAATAAAGCGAGAACCAGGTTTGCCACAAATCGAGAAGTTGAGTTCGCAAATTGAAACTGTAACAATTTCTGATGATGAAGACGATCCCAAGGAAGTATTAAGCTTTAATCCTAAAGCCGGTTCAGATTTAGAGGAAAACAAACCCAGTGATGCAAGCGTACGAAGTTTTTTTGGGGAGGAAGAACCCTACATTATGGATACGAAAAATGCCGGAAATATTGGTCGCTTTTTGAATCATTCCTGTTCTCCAAACGTCTTTGTGCAAAATGTATTTGTCGACACTCACGATTTGCGTTTTCCTTGGGTCGCATTCTTTTGTTCGCAATTTATCAGAGCTGGAACTGAACTGACATGGAATTATAATTATGACATTGGAAGTGTACCTGGCAGGATACTCTATTGCCACTGTGGATCTTTAGAGTGTAAAGGTCGATTACTTTAA
Protein Sequence: MEEDDMDMEIDDTISNHNATIIVREATGVQIIGGPAADLSTSTSTSTPSTPSKMEESQVKLEKKPASKPADIVVLDDDEEPAPPKSLEKKSSGDDQVEIIDLVEEKSISSKCINYSCASGKDLMIAPNMCMSYYRVKNPGNGKKEVCAECFNLALKDYDSLATELLQGNILGKVKVPIRNDTVEIDDSDEEDVESRIPEMDKEDIALVEKNFEKILIETMKQLNFDAQVNKETTYLKEQSSKLCKSRTELQAMIKETRNTLDKIQLNLYNEFRSETRETCVISIIDDHFAASTPIIRNESGRFQQPSPRKSQRTVTKKVSYSDMENPSSPKVTSNEELIEVPKDLPVLGSIEPPAIILEDLYFISRENSSGSWIKARLKSIVSSGTVVNGAPITTPHYKMLELKQHKERIVNGKTVASMKSSKIRLETGTRVIAAFKEVSNTGEIKKPRHDPFYPGIVAEPPVAQNKYRYLIFFDIGYSQYVHYSSVHVVFEYSKNVWEDMHVDSRTFIKKYLESPDRPMVKLSKGQTVKVEYQGKWLLCTIMNVDCSLALVFFDSLNRTEWIYRGSPRLSPMFKEEQNASKRQLGGRPSNRKPGSESMVQYTKNADFDKPENEAAAPVRAVARKSTARPENSTARSGGFVPFLPPVSNNVVHMEPTSKIMYFTPRDQVITQRIYRTHNCSPACKDYIRHNLSKLRGHNPLSKPLLCGWARITQKVKGRKEILYKAPCGRILRNIVEIHKYLRLTKSEMTVDLFDFNHMVRCLAEFNVECAPDPKDLSKGLEQVPIPVINGINNDMLDFCNYAIKRVPMEDVPLNVDPEFLIGCDCTDDCQDKSKCSCWQLTLEGSRYMGRNVDPNNIGYVYRRLHEQVLTGIYECNSRCKCASTCLNRVVQHPMSIKLQVFRTHNRGWGIRCVNDVPQGTFICIYAGTIHTEQMANEDGVTYGDEYFAELDYIENCEKHKEDYESDVADPDSPRSRSPPSPDEDDDDDDDDDGGRRRRRRGNKKIYDNDFCITFPLSRSDTWEKSMSLRKRTQEESRAEAAEKELKIKREPGLPQIEKLSSQIETVTISDDEDDPKEVLSFNPKAGSDLEENKPSDASVRSFFGEEEPYIMDTKNAGNIGRFLNHSCSPNVFVQNVFVDTHDLRFPWVAFFCSQFIRAGTELTWNYNYDIGSVPGRILYCHCGSLECKGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -