Basic Information

Insect: Lacanobia wlatinum
Gene Symbol: sem-2
Assembly: GCA_947578705.1
Location: OX388036.1:3653924-3656121[+]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.5e-29 3.3e-26 92.2 0.6 1 69 53 121 53 121 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.5e-29	3.3e-26	92.2	0.6	1	69	53	121	53	121	0.99

Sequence Information

Coding Sequence: ATGGCCGCTAAAAGAAGTTTCATTTTGAATAACGAAAATTCTAAAACCAACACCGGCCAGCCGAACTTAAAACCGTACAGAAACGACGAAAAAAAGCTGCCTAGCAACAGACTAGTCACGAAAACCAAACACACAAAGAAGAACAACCcaaaccacattaagaggccgatgaacgcgttcatggtctggtcgcagatagagcgcaggaaaatatgcgaacagacgccagacatgcacaacgcggagatctccaagaacctcggccgcgtgtggaagacgctcaacgacgaagagcgccagcctttcatcgacgaggcggagaggctgcggcagctgcacatgcgggagtaccccgactacaagtacaggccgcgcaagaAGACCGCCAAGTCCGACAGGTCCGGGCCCAAGACCGGAGGCGTGACGAAGCCAAAGCGCAAACAGCGCGCCGACTCCAACAACAACAGGGGCGTCGCCAGGCGGAGGAGACCTGTCCCGACGGTGCCGAGTGTACCCATGGACACTCCTGCGCCCCCGCCGCTGCCGGCCAGCCCCGCGGGTTCGCCAGACTCCCCTGAATCAGCCTGCTTCTACGAAGACCATAATCGTCGTGAGCAGGCAGACCTAACAGATCTCTACTCCATCACGGACCTGCTGCCGCTCCCCACGGACTGCGAGGTAGACCTGGAGGCCCTCACGACGGACATCGACTCGTTCGAGACCGCGTCGTCGTCATCGGGCTCGCACTTTGAGTTCTCGTGCACGCCCGACGTGTCGGACATGCTGAGCGAGATCGGCGTAGCGGGCGACTGGGTCGACCACACGTTCTCGTCGTATCTGACGTCGTCTTAG
Protein Sequence: MAAKRSFILNNENSKTNTGQPNLKPYRNDEKKLPSNRLVTKTKHTKKNNPNHIKRPMNAFMVWSQIERRKICEQTPDMHNAEISKNLGRVWKTLNDEERQPFIDEAERLRQLHMREYPDYKYRPRKKTAKSDRSGPKTGGVTKPKRKQRADSNNNRGVARRRRPVPTVPSVPMDTPAPPPLPASPAGSPDSPESACFYEDHNRREQADLTDLYSITDLLPLPTDCEVDLEALTTDIDSFETASSSSGSHFEFSCTPDVSDMLSEIGVAGDWVDHTFSSYLTSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00906145; iTF_00924673; iTF_01093089; iTF_01317281; iTF_01342209; iTF_00171746; iTF_00000324; iTF_00124260; iTF_00785988; iTF_00908836; iTF_01192708; iTF_00114085; iTF_00157189; iTF_01075429; iTF_01487685; iTF_00041766; iTF_00049894; iTF_00111654; iTF_00112486; iTF_00622822; iTF_00677606; iTF_01340102; iTF_00040807; iTF_00123367; iTF_00236616; iTF_00375208; iTF_00449097; iTF_00809129; iTF_00810057; iTF_01029257; iTF_00036714; iTF_00281322; iTF_00441482; iTF_00636394; iTF_00637642; iTF_00018155; iTF_00038763; iTF_00706955; iTF_00187148; iTF_00771916; iTF_00785196; iTF_00850732; iTF_01030220; iTF_00001165; iTF_00823885; iTF_00037806; iTF_00301166; iTF_00711854; iTF_00973774; iTF_01076494; iTF_01094030; iTF_00017327; iTF_00300207; iTF_00726351; iTF_01064655; iTF_01361615; iTF_00172944; iTF_00783472; iTF_00831216; iTF_01197712; iTF_01538736; iTF_00282385; iTF_00758161; iTF_00951825; iTF_00968017; iTF_01173265; iTF_00364018; iTF_00404914; iTF_01230578; iTF_01527218; iTF_00072147; iTF_00274419; iTF_01117203; iTF_00122388; iTF_00185300; iTF_01316340; iTF_00120501; iTF_01152149; iTF_00450102; iTF_01027318; iTF_01312214; iTF_01439926; iTF_00446135; iTF_00823031; iTF_01491927; iTF_00186168; iTF_00745688; iTF_00147449; iTF_00273593; iTF_00121434; iTF_00667482; iTF_00039803; iTF_00177115; iTF_01119323; iTF_01221563; iTF_01260091; iTF_01285531; iTF_01332699; iTF_01441083; iTF_01526011; iTF_00113308; iTF_00383644; iTF_01028284; iTF_01264604; iTF_01026173; iTF_01338749; iTF_01360605; iTF_01363101; iTF_00042622; iTF_00327070; iTF_00374110; iTF_00425374; iTF_00821822; iTF_01031134; iTF_01094910; iTF_01118302; iTF_01166686; iTF_01425054; iTF_00447135; iTF_00784383; iTF_00907039; iTF_00907871; iTF_01246975; iTF_00237568; iTF_00888256; iTF_00952704; iTF_01084257; iTF_01534822; iTF_01533924; iTF_01532007; iTF_01533040; iTF_01062792; iTF_01063752; iTF_00685429; iTF_01061882; iTF_01085227; iTF_00302098; iTF_00445170; iTF_00928694; iTF_01377463; iTF_01502079; iTF_00635395; iTF_00926594; iTF_00935716; iTF_00206053; iTF_00206981; iTF_00634472; iTF_00044491; iTF_00143056; iTF_00895930; iTF_00666523; iTF_00033793; iTF_00032900; iTF_00825725; iTF_00826957; iTF_00947876; iTF_00433140; iTF_00432189; iTF_01149572; iTF_01144518; iTF_01140905; iTF_01142378; iTF_01138927; iTF_01143814; iTF_01145256; iTF_01148800; iTF_01147362; iTF_00889203; iTF_00859460; iTF_00931396; iTF_00932543; iTF_00858534; iTF_01010346; iTF_00063580; iTF_00345799; iTF_01358859; iTF_00341306; iTF_00407577; iTF_00406742; iTF_00021311; iTF_01135747; iTF_00156232; iTF_00462381; iTF_00342190; iTF_00155288; iTF_00325371; iTF_01134781; iTF_01072484; iTF_00410273; iTF_00657186; iTF_00654275; iTF_00289604; iTF_00656136; iTF_00659434; iTF_00660302; iTF_00871281; iTF_00680532; iTF_01133716; iTF_00409272; iTF_00658393; iTF_00411451; iTF_00772870; iTF_01245927; iTF_00010061; iTF_01464149; iTF_00009015; iTF_00148462; iTF_00149386; iTF_00412498;
90% Identity: iTF_00906145; iTF_00924673; iTF_01093089; iTF_01342209; iTF_00171746; iTF_00124260; iTF_01192708; iTF_00041766; iTF_00049894; iTF_00111654; iTF_00622822; iTF_01340102; iTF_00040807; iTF_00123367; iTF_00375208; iTF_00449097; iTF_00809129; iTF_00810057; iTF_01029257; iTF_00036714; iTF_00441482; iTF_00018155; iTF_00038763; iTF_00771916; iTF_00785196; iTF_00850732; iTF_01030220; iTF_00037806; iTF_00301166; iTF_00711854; iTF_00973774; iTF_01076494; iTF_01094030; iTF_00017327; iTF_00300207; iTF_00726351; iTF_01064655; iTF_01361615; iTF_00172944; iTF_00783472; iTF_00831216; iTF_01197712; iTF_01538736; iTF_00758161; iTF_00951825; iTF_01173265; iTF_00364018; iTF_01230578; iTF_01527218; iTF_00274419; iTF_01117203; iTF_00122388; iTF_00120501; iTF_00450102; iTF_01027318; iTF_01439926; iTF_00446135; iTF_00823031; iTF_00745688; iTF_00147449; iTF_00273593; iTF_00121434; iTF_00667482; iTF_00039803; iTF_00177115; iTF_01119323; iTF_01285531; iTF_01441083; iTF_01526011; iTF_00383644; iTF_01028284; iTF_01264604; iTF_01026173; iTF_01338749; iTF_01360605; iTF_01363101; iTF_00042622; iTF_00374110; iTF_00425374; iTF_01031134; iTF_01094910; iTF_01118302; iTF_01425054; iTF_00447135; iTF_00784383; iTF_00907039; iTF_00907871; iTF_01246975; iTF_00237568; iTF_00888256; iTF_00952704; iTF_01084257; iTF_00785988; iTF_01533924; iTF_01534822; iTF_01532007; iTF_01533040; iTF_00114085; iTF_01317281; iTF_00112486; iTF_00187148; iTF_01316340; iTF_01312214; iTF_00113308; iTF_01085227; iTF_00869616; iTF_00908836; iTF_01075429; iTF_00677606; iTF_00281322; iTF_00636394; iTF_00637642; iTF_00709226; iTF_00706955; iTF_00823885; iTF_00282385; iTF_00968017; iTF_00404914; iTF_01152149; iTF_01491927; iTF_01332699; iTF_00821822; iTF_01166686; iTF_00302098; iTF_00445170; iTF_00685429; iTF_00928694; iTF_01377463; iTF_01061882; iTF_01062792; iTF_01063752; iTF_01502079; iTF_00889203; iTF_00931396; iTF_00932543;
80% Identity: iTF_00952704;