Basic Information

Insect: Ischnus inquisitorius
Gene Symbol: Hr39_3
Assembly: GCA_963924025.1
Location: OZ001245.1:4301779-4306024[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.43 4.6e+03 -3.1 9.7 50 164 209 325 171 369 0.62

2 4 2 2.2e+04 -7.2 8.0 82 124 375 411 331 467 0.43

3 4 3.6e-08 0.00039 20.2 0.0 1 21 536 556 536 561 0.92

4 4 6.3e-74 6.8e-70 236.8 0.0 90 408 595 911 568 911 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.43	4.6e+03	-3.1	9.7	50	164	209	325	171	369	0.62
2	4	2	2.2e+04	-7.2	8.0	82	124	375	411	331	467	0.43
3	4	3.6e-08	0.00039	20.2	0.0	1	21	536	556	536	561	0.92
4	4	6.3e-74	6.8e-70	236.8	0.0	90	408	595	911	568	911	0.84

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCACGGAGGGCCCGGGCTGGTGGCCTCCGGCACAATCGTGGAAGTCATCAAccacctcgtcgtcgtcgctgccgATTCCTACGTCCCGCACACTCGAGACAGGAAAGAACGTTTCCGTCACGACGATCAACGTACCACCGGCCCAGGAAATGCACGACGgtaaaagcGTCTGCAAGTTCGTGGGAGGACAGAACGGCGTGACCGTATCGGTGGTCTCGAGTTGCGGCAGTGGTACCGGTAGCGGAATGGGCACGGGACCAGGCGGAGGCGGTGGAGGTGGCGCGTCTTCCTCGTGTCCGGACTCGAGTTccctcgacgatctcgaggacAGCGACGGCGAAGTAAGCAAGATCGACTTTCGCGGCGTTAATctgcgaacgaagaagaagcgcgaTGCGAACGGCGGAACGGAGAACGATTGCGGCGCCGTGGGCGCCGACAATctcgagcagcagcagcccgAAAGACCGATGTCATGGGAGGGCGAGCTGTCCGATCAAGAAATGTCGTCCAACACGATCACCAATCAGGATCACGAGGAAACGTCGATGGAGGGTGTTCAGGTATGCGGCGCGAGTCCAGGACCCCAGGAGCAAAAGTTTCCGATAAAGCCCGAGCCGGATTTTCGTTCGAGTCCCGGCCTCGGTATAAACTCTCACAACGACGGAAATTTGACGCTGTCGCACGCGCAACAgttgcagcagcagcaggccCATCAGCAGCAGCGCGGAATCGAGAGTCTCGAGCAAACGCAGCAGAGCGACCTGCCTCTGTTGGTTGGCAAGTTGCTCGGTGGTTACAACAGCTCGACGCCGAATCACAGTCCGATACTGAATCCTCGTCATCATCTGACGAAGCACAGTCACACGAGGTCACAGGTACCGTCACCGGATTCGGCGATACACTCGGCTTACAGTGTCTTCAGTTCGCCGACGCAGAGTCCTCACGCGGCGCGTCATTCGGCCCTCGGTGCGGGAAGTCCCGtgccctcgtcgtcgttatcgTTGTCGCGTCACAGTTTCAACAACTCCACGTCGTCCCTATCCTTGTCATTGTCGCACTCGCTGTCGCGAAACAATTCCGACGCTTCGAGCAGTTGTTACAGTTACGGCTCGTTGAGTCCACCGACTCATTCGCCGGTACAACAGCCGAGGCATTCGCACGGtcagcatcatcatcatcagcagcaacagcagcagcaacaattGCCGCAAGGCAGCCCGTTGCATCTGCCCTCGGCATCGTCGGGCAATCCTCATCACTACTCGGCTCCGGGCTCGGAAATATCGTCCGAGGGCCATCCCGAGGATCAGGAAGATTGCAAAATACCATCGGCCCCGTCGGGCATATCGACGAGGCAACAATTGATAAACAGTCCGTGCCCGATATGCGGCGACAAGATAAGCGGCTTTCACTACGGTATATTCTCGTGCGAATCTTGCAAGGGTTTCTTCAAGCGTACCGTGCAAAATCGCAAGAATTACGTTTGTCTCAGAGGCGCCGGTTGTCCCGTTACCGTCgcaacgagaaagaaatgtCCGGCTTGCCGTTTCGACAAGTGTCTCAATATGGGAATGAAACTCGAGGCGATAAGGGAGGACAGAACGCGCGGCGGTAGGAGCACTTATCAATGCACTTACACACTGCCGGCGAATCTGATCGGCAGCTCGGCCGGCGGTATGCCCGGCGACAAAATGACCGGCGGTGCATGCAGCCCAGCGCCACCGGGCTCGGAGCATCATCATTCGGCGCGACATCATTGGAATCATTCGCACAAGATCCAAGCGGTGCCGCAACTCTTGCAGGATATCATGGACGTCGAGCATCTTTGGCACTACAACGACAACGATCGAACGACCGTCAGTAGTCAGAACTCCGGCCACGGCGCCAACGGAAGCCCGATGAGCAACGATTTAACCGGTGGTCTCGGTAGTCTCGGTAACAATTCCGGCAGCGGTAGCGGACCGAGCCGCAACGGCAATGTCGACAGTCGCGAACAAACGAGATCGACCACGACCGGAAGCTCAACGAACAACGAACATCAGCAGACGAACTCGTCGACGAACAATCCAACGAGCGCCGGTACGAATTCGACGAATCCCAATGGTAATTCGACTCAACATCCGGATTTCTTGTCGAATCTGTGCAACATCGCGGATCATCGACTGTACAAGATCGTCAAGTGGTGCAAGAGCCTGCCgcttttcaaaaatatatcgatcgacgatcagATATGCCTTTTGATCAATTCGTGGTGCGAATTGTTACTCTTCTCGTGCTGCTTTCGGAGCATGAGCACACCCGGAGAGATAAGAGTATCGCTCGGGAAATCTATCACTCTCGAACAAGCGAGGCAATTGGGCTTGGCTACGTGCATCGAGAGGATGCTGGCCTTCACGAATAATCTCAGGAGGCTGAGGGTCGATCAGTACGAATACGTGGCGATGAAAGTGATAGTCTTGTTAACTTCGGATACGAGCGAGCTGAAGGAACCCGAGAAAGTTCGAGCGTCGCAGGAAAAAGCTCTGCAGGCGTTGCAGCAATACACGATCGCCAAGTATCCGGAAATGCCGGCGAAATTCGGTGAGCTTCTATTGCGAATACCGGATCTGCAGAGGACATGCCAAGCCGGCAAAGAGTTGTTGAGTGCTAAACGCGCCGAGGGCGAGGGCAGCTCTTTCAATCTATTGATGGAATTGCTGCGAGGAGATCACTGA
Protein Sequence: MSEQNGPTEGPGWWPPAQSWKSSTTSSSSLPIPTSRTLETGKNVSVTTINVPPAQEMHDGKSVCKFVGGQNGVTVSVVSSCGSGTGSGMGTGPGGGGGGGASSSCPDSSSLDDLEDSDGEVSKIDFRGVNLRTKKKRDANGGTENDCGAVGADNLEQQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCGASPGPQEQKFPIKPEPDFRSSPGLGINSHNDGNLTLSHAQQLQQQQAHQQQRGIESLEQTQQSDLPLLVGKLLGGYNSSTPNHSPILNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHGQHHHHQQQQQQQQLPQGSPLHLPSASSGNPHHYSAPGSEISSEGHPEDQEDCKIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGSSAGGMPGDKMTGGACSPAPPGSEHHHSARHHWNHSHKIQAVPQLLQDIMDVEHLWHYNDNDRTTVSSQNSGHGANGSPMSNDLTGGLGSLGNNSGSGSGPSRNGNVDSREQTRSTTTGSSTNNEHQQTNSSTNNPTSAGTNSTNPNGNSTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIAKYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_00057987;
80% Identity: iTF_00841156;