Ibis013261.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Idaea biselata
Gene Symbol
ttk
Assembly
GCA_958496205.1
Location
OY292398.1:19897666-19905829[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.2e-27 2.9e-24 86.1 0.1 1 102 21 119 21 123 0.93

Sequence Information

Coding Sequence
ATGGGAAGTGAGCACTATTGCCTAAGGTGGAACAATCATCAGAGCAACCTGCTGGGAGTATTCAGCCAGTTGCTACACGACGAGAGCTTAGTGGACGTCACACTCGCCTGCTCGGAGGGCGCATCCATCAGGGCTCATAAGgTAGTATTATCGGCGTGCTCATCGTACTTCCGGTCTCTATTCGTGGACCACCCGTCGCGTCATCCCATCGTGATCCTGAAAGACGTGGGCCTGGAAGAGTTGCGGACGCTCGTCGACTTCATGTACAAGGGCGAGGTCAACGTACAGTATTGTCAACTGCCAGCGCTCCTCAAAACTGCTGAGAGCCTTCAGGTCAAAGGCCTAGCTGAAATGACGACACTTAGTGCAGCTGGCATTGATGCTAGAAACGTCCCGGAACCAATGGAAGAGTGCCAGCCTCCGGACACCAGGGAGTGTCAAGAAACACATGAAAAATCAGAAAACAGAGAAAACCGAGACAAAGAGGACAGACGTGAACCAAAAGATGTAAGAGATATCAGAGACGTCAAAGAACCCCGTGACTCGAGAGAGACGAGGGATCACAGAAGCAGAGAACACAGAGAATCTCGGGAATTACGAGAGCCTCGTGAACTTCGCGATTTGAGGGAACAAAGGGAACCACGCGAGCCCCGAGACTTAAGGGAGCATCGAGAGCTCCGAGATCACAGGGAATCTAGAGATCCCAGGGATCTAAGAGAATTGCGCGAAATGAATGAATCTCGTGATCATAGAGATTTACGAGACATTAGAGACCCCAGAGAAGCACCTGAAGCTTCTCCACCTAGGGCATCCCCTTTGCTTTCAGTTCGGCGGTTTAGGCCGGAAACTTCAGTAGAAAATCCTACCCTTACGCATCCACCTATTCCTAAAGACGAACCCCCTGACGAACCTATGCGTGCGTCGTCACCTGAAGACGATACCGTGTCAATACGGTCTAATGGGGCCCAAAATGACAATATGGGATTAAACATGACAATTAACAGCCACAGTAGTAGCAGCGTGTTAGGCACTAGATATTCGCCGGTGGAGAGGCTCAGCGTACTAAATACCTTGGGCCATGGTGTTCTACCGCATCCTTCGCACACGTCGCTGTCAAGTCCGAGAAGTGAGCCCATTGCAGGCCCTTCGGGGCTGCCACCGGTCCAACAAGTTCCCCTGTCACTGAAAAAAGAAATTGACTGGGATCGACCTGAGGACAAAGCTGGGGAACCTTCCAATGATTATCGACTACAACATGAATCGGAGTACGATGGGTCCGGTAGGGGGAGAATAGACGAGGGGGAAAGGGGGTATCCTTGCATTCACTGCGGCGCGGCGTTTCCACACCAGAGCAAACTGACACGGCACATATTGACGACTCACACGCTCGACACTTTGAAGTACCGAGACGCGATCCTAGGCCGGCCGTTGGGGCTGCCCATGATAGGGCAGTTTCATGAACCGACCTACCTCACCATGCACCCTGAAGAGGCTCCTATAGACCTAGACATCGGACCCGTCGAGCCAGGAAACGTCGTGCTCTGCAAGTTCTGTGGGAAGAGTTTTCCTGACGTCTCCTCGCTGATTGCCCATTTGCCGGTCCACACCGGCGATAGACCGTTCAAGTGTGAATTTTGTGGAAAGGCGTTTAAACTTAGACATCATATGAAAGACCATTGTAGAGTTCACACAGGTGAGAGGCCATTCCGATGTGGTTTATGCGGTAAGACGTTTTCACGATCGACTATACTAAAAGCTCATGAGAAGACCCACTATCCGAAGTACGCGCGGAAATTCCTATCACCAAGTCCCGTCGATACGGAAGAAGAGAGTCCGCATCAATGA
Protein Sequence
MGSEHYCLRWNNHQSNLLGVFSQLLHDESLVDVTLACSEGASIRAHKVVLSACSSYFRSLFVDHPSRHPIVILKDVGLEELRTLVDFMYKGEVNVQYCQLPALLKTAESLQVKGLAEMTTLSAAGIDARNVPEPMEECQPPDTRECQETHEKSENRENRDKEDRREPKDVRDIRDVKEPRDSRETRDHRSREHRESRELREPRELRDLREQREPREPRDLREHRELRDHRESRDPRDLRELREMNESRDHRDLRDIRDPREAPEASPPRASPLLSVRRFRPETSVENPTLTHPPIPKDEPPDEPMRASSPEDDTVSIRSNGAQNDNMGLNMTINSHSSSSVLGTRYSPVERLSVLNTLGHGVLPHPSHTSLSSPRSEPIAGPSGLPPVQQVPLSLKKEIDWDRPEDKAGEPSNDYRLQHESEYDGSGRGRIDEGERGYPCIHCGAAFPHQSKLTRHILTTHTLDTLKYRDAILGRPLGLPMIGQFHEPTYLTMHPEEAPIDLDIGPVEPGNVVLCKFCGKSFPDVSSLIAHLPVHTGDRPFKCEFCGKAFKLRHHMKDHCRVHTGERPFRCGLCGKTFSRSTILKAHEKTHYPKYARKFLSPSPVDTEEESPHQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00836075; iTF_00701537; iTF_00702116; iTF_00696583; iTF_00698441; iTF_00705546; iTF_00705163; iTF_00704142; iTF_01161839; iTF_00701201; iTF_00703506; iTF_00703092; iTF_00704506; iTF_01161498; iTF_00696893; iTF_00699358; iTF_00698751; iTF_00699680; iTF_00702464; iTF_00321716; iTF_00321994; iTF_00697844; iTF_00697492; iTF_00706521; iTF_00706159; iTF_00874593; iTF_00875754; iTF_00875445; iTF_00874873; iTF_01034721; iTF_01033858; iTF_01035054; iTF_00842803; iTF_01034133; iTF_00843095; iTF_00958764; iTF_00959000; iTF_00959770; iTF_00959518; iTF_00960277; iTF_00960521; iTF_01115812; iTF_01495142; iTF_01495880; iTF_01496138; iTF_01494423; iTF_01494679; iTF_01116056; iTF_01495392; iTF_00180868; iTF_01130128; iTF_00180593; iTF_01130395; iTF_01528774; iTF_00661455; iTF_00661809; iTF_01528438; iTF_00362121; iTF_00361761; iTF_00377582; iTF_00377229; iTF_01529326; iTF_01529640; iTF_00662355; iTF_00662668; iTF_01336055; iTF_01336398; iTF_01171898; iTF_01171585; iTF_01183387; iTF_01183035; iTF_00318207; iTF_00318487; iTF_00120064; iTF_00119721; iTF_00857160; iTF_00856775; iTF_00209001; iTF_00208034; iTF_00208411; iTF_00209406; iTF_01176522; iTF_01176295; iTF_00663212; iTF_00663586; iTF_00407149; iTF_00407981; iTF_00406872; iTF_00407707; iTF_00236752; iTF_00237059; iTF_01219891; iTF_01220199; iTF_00811161; iTF_00811536; iTF_00468282; iTF_00468566; iTF_00737914; iTF_00737611; iTF_01509722; iTF_01510026; iTF_00187291; iTF_00187640; iTF_00639102; iTF_00638768; iTF_01490270; iTF_01490575; iTF_00461951; iTF_00461693; iTF_00632895; iTF_00633209; iTF_00700575; iTF_00700244;
90% Identity
iTF_00836075; iTF_00837040; iTF_00836706; iTF_00835126; iTF_00834769; iTF_00838010; iTF_00837699;
80% Identity
iTF_00836075;