Hcos029769.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hypsopygia costalis
Gene Symbol
fd96Ca
Assembly
GCA_937001695.2
Location
CAKZJU020000630.1:481308-482093[+]

Transcription Factor Domain

TF Family
Fork_head
Domain
Fork_head domain
PFAM
PF00250
TF Group
Helix-turn-helix
Description
The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.1e-39 4.4e-36 124.1 0.0 1 88 12 98 12 98 0.97

Sequence Information

Coding Sequence
ATGCCCAGACCGACACGTGAGTCCTACGGTGACCAGAAACCACCATTTTCATATATAGCTTTGACTGCAATGGCGATCTGGAGCTCGCCGGAACGCATGCTGCCGCTATCGGAGATCTACCGGTTCATCACAGACAGATTCCCGTACTACCGTCGTAATACGCAACGCTGGCAAAACTCGCTGCGGCATAACCTGTCCTTCAATGACTGCTTCGTCAAGGTGCCACGCCGGCCGGACCGGCCCGGCAAGGGAGCCTACTGGACATTACACCCCCAAGCCTTCGATATGTTCGAAAACGGTTCGCTCCTTAGAAGACGGAAGCGCTTCAAGCTGCATAAAGGCGAAAAAGATAGCTTAAATGCAGAGCTGGCGGCTCTCGCCAGTTTCAATAGAGCATTTTTGGCAAGACAGGCAGGAGCTCCACCGCCAGGGACGATGCCTAATGGCAGTTTATATTCTCCAGCCGTAACGCTTTGCTCGAGACCTAGTCCAGAACCAATCGAGGCCCCGGACACTGCTGCTTTGCTGCCTGCGGGGCCACGACCCCGACGGGCGTTTACGATAGATGCTTTGTTGGAGCCTGAACCTCGACGATTGTCACCGTCTcctccgccaccgccaccgctgcAGCCGCATTGCCCGCTACCATTACCCCCGTCACCTTACTTGTTGGCAGCGCAGAGATATCACGCAGAGTTGCTCGCAGGCTTACAACAATCCTGCCTGCCTCCATTATGGACTTGGCGAGATACGAGTCAATTTTCACATTATACGCTTAATTCATGA
Protein Sequence
MPRPTRESYGDQKPPFSYIALTAMAIWSSPERMLPLSEIYRFITDRFPYYRRNTQRWQNSLRHNLSFNDCFVKVPRRPDRPGKGAYWTLHPQAFDMFENGSLLRRRKRFKLHKGEKDSLNAELAALASFNRAFLARQAGAPPPGTMPNGSLYSPAVTLCSRPSPEPIEAPDTAALLPAGPRPRRAFTIDALLEPEPRRLSPSPPPPPPLQPHCPLPLPPSPYLLAAQRYHAELLAGLQQSCLPPLWTWRDTSQFSHYTLNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00655906; iTF_00659276; iTF_00660121; iTF_00658171; iTF_00656956; iTF_01072262; iTF_00680336; iTF_00289440; iTF_00654049; iTF_00026659; iTF_00177891; iTF_00277187; iTF_00647811; iTF_01387427; iTF_01386533; iTF_01388280; iTF_00457060; iTF_00775076; iTF_00779332; iTF_00781638; iTF_00621037; iTF_00778605; iTF_00776591; iTF_00780079; iTF_00780852; iTF_01181718; iTF_00782455; iTF_00777819; iTF_00775868; iTF_00722853; iTF_00212239; iTF_00247855; iTF_00213232; iTF_00246997; iTF_00159642; iTF_00149190; iTF_00715622; iTF_00871110; iTF_00323304; iTF_00148299; iTF_00077302; iTF_01090502; iTF_01340963; iTF_00197191; iTF_00468007; iTF_00723783; iTF_01020039; iTF_01463974; iTF_00008713; iTF_00009818; iTF_01463071; iTF_01133535; iTF_00075272; iTF_00074291; iTF_00420360; iTF_00421164; iTF_00419597; iTF_00418783; iTF_01331240; iTF_01333543; iTF_00076266; iTF_00621834; iTF_01264211; iTF_00967860; iTF_00821589; iTF_00806506; iTF_01073418; iTF_01359531; iTF_00287874; iTF_00278924; iTF_00409100; iTF_00411233; iTF_00642156; iTF_00801612; iTF_01017552; iTF_01091506; iTF_00953331; iTF_00954222; iTF_01018391; iTF_00674124; iTF_00250274; iTF_00844131; iTF_00935491; iTF_01543715; iTF_01542771; iTF_01544694; iTF_01546457; iTF_00791012; iTF_00926404; iTF_00156069; iTF_01545574; iTF_00790055; iTF_01401095; iTF_00462184; iTF_00635208; iTF_00994185; iTF_00342026; iTF_00826637; iTF_01547341; iTF_00055214; iTF_00364726; iTF_00204942; iTF_00162319; iTF_00649839; iTF_00032720; iTF_00033635; iTF_00142908; iTF_00390192; iTF_00666320; iTF_00913424; iTF_01135568; iTF_01134598; iTF_00634129; iTF_00895730; iTF_01207924; iTF_00275061; iTF_00825397; iTF_01500917; iTF_00155127; iTF_01403255; iTF_00206808; iTF_00648922; iTF_01209018; iTF_01151036; iTF_01021002; iTF_00818173; iTF_01172143; iTF_01336638; iTF_00325183; iTF_01503661; iTF_00412334; iTF_00959982; iTF_00958518; iTF_00959226; iTF_00827792; iTF_00197937; iTF_00736434; iTF_00007822; iTF_00772690; iTF_00352852; iTF_00353890; iTF_01282036; iTF_01312052; iTF_01317092; iTF_01451284; iTF_00354901; iTF_00355940; iTF_01078005; iTF_01506980; iTF_01507879; iTF_00824520; iTF_01078888; iTF_01506153; iTF_00984842; iTF_00796337; iTF_00843313; iTF_00985810; iTF_01079707; iTF_00695292; iTF_01080544; iTF_00457828; iTF_00896586; iTF_01034346; iTF_01033534; iTF_00842463; iTF_00774325; iTF_00461369; iTF_01569077; iTF_00027574; iTF_00236462; iTF_01489954; iTF_00276086; iTF_00256663; iTF_00255628; iTF_00405744; iTF_00150296; iTF_00858360; iTF_01010180; iTF_00787433; iTF_00859273; iTF_01358702; iTF_00290479; iTF_00063392; iTF_00947713; iTF_00112325; iTF_01316133; iTF_00113150; iTF_00113151; iTF_00432945; iTF_00431944; iTF_00341150; iTF_00345628; iTF_00662047; iTF_00006105; iTF_01081398; iTF_00651546; iTF_00011756; iTF_00012748; iTF_01220468; iTF_00720021; iTF_00072538; iTF_00146206; iTF_01302104; iTF_00640094; iTF_00855706; iTF_00673307; iTF_00025089; iTF_00830978; iTF_01377283; iTF_00017156; iTF_00427909; iTF_00428814; iTF_00818963; iTF_01429748; iTF_00785829; iTF_00785830; iTF_00784206; iTF_00783239; iTF_01083111; iTF_01251559; iTF_00006896; iTF_01415634; iTF_00383432; iTF_01416584; iTF_00677353; iTF_01082250; iTF_01246638; iTF_01285358; iTF_00071215; iTF_01361393; iTF_01362305; iTF_01362906; iTF_00662898; iTF_00171571; iTF_00785013; iTF_01245749; iTF_01437781; iTF_00971047; iTF_00970221; iTF_01438711; iTF_01538551; iTF_01424859; iTF_00819870; iTF_01064446; iTF_01436830; iTF_00144380; iTF_00207676; iTF_00208644; iTF_00795517; iTF_00875966; iTF_00875114; iTF_00874265; iTF_01124414; iTF_01125258; iTF_00751839; iTF_01071452; iTF_00347328; iTF_01279999; iTF_01281119; iTF_00960748; iTF_00942624; iTF_01161129; iTF_00410094; iTF_00124975; iTF_00044272; iTF_00205874; iTF_01564370; iTF_00810809; iTF_01158528; iTF_01502784;
90% Identity
iTF_01264211;
80% Identity
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