Hrec015681.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyppa rectilinea
Gene Symbol
br
Assembly
GCA_951799385.1
Location
OX637313.1:1139231-1149126[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.9e-29 2.3e-26 93.1 0.1 1 100 22 117 22 121 0.95

Sequence Information

Coding Sequence
ATGGTGGACACACAGCATTTCTGCCTCCGCTGGAACAACTACCAGAGCAGTATCACCAGCGCCTTCGAGAATCTTCGTGATGACGAGGATTTCGTCGACGTCACATTGGCCTGCGACGGCAAGAGTTTGAAAGCACATCGGGTTGTACTGTCAGCCTGCAGCCCTTATTTCAGGGAGCTATTGAAGTCAACACCATGCAAGCACCCAGTGATCGTGCTTCAAGACGTGGCATTCACGGATCTACACGCGCTGGTCGAGTTCATCTACCACGGAGAGGTCAACGTGCATCAGAGGAGTCTCTCCTCCTTCCTCAAGACTGCTGAGGTCCTCCGCGTGTCTGGACTCACGCATAATGAGAACGCTCAGGGGCCGCTGCTGCAGCCAATGCGCGCGCCCTCCACAACATCGCCGCACACGCCGCCGCACTCCGCTCACAGCACGCACATCAGCCACACGCCAACTTACGACCGTCTGGAAGAGGCTTTACTCCAGCCAGCAACGTCAAGCGTCCAACAACTCATGCGCAGGACCCCGCTGCCGCCGCGCCGGCTCAGCCGCTCCGCCGACAACAGCCCCGACGTCATCAAGCGTCCTCGCCACGACAACAACAACGAGCAACCACAGATTCACGCAACTGACTTTTCAACTAAAAACAATACTCATGCCCGCGGGCATAACGAGACGGGGAACAACGGGAACGGGATCTCTAATAGCAGCTCCTCGCCTTCCCCGAGGCTCATGGATGACGTGAAGAATGAGCCCATTGACATGATCTGTCCCTCCAACCCGGATATTGACAGGAGCACGGATGATACGCCGCCGCATCATCACAGACCACTTGGAGTAGGCCCGCCGTCGCGCGGCAGCTCAGCTGATGCTGAAGAGTGCACGCCACCACCGCACCCACCACCATTCATACAGCCACCAGACTCGAAACTCTTCAACCCGGCGAACACATACAACTTTACTATGGAAGCTCTGTCGCATCCTTCATTGACTGGTCTCCAGAGTCCCTTGGCTCCGGACGGCATCGCAAGTACTTCCCAAGTTGGCCCTCTGGGCGCGGGGCACCGCTGCGAGGTGTGCGGCAAGCTGCTGTCGACGCGGCTCACGCTCAAGCGGCACACCGAGCAGCAGCACCTGCAGCCGCTGCACTCGGCGCGCTGCTCCCTGTGCCACAAGGTGTTCCGAACGCTCAACTCGCTCAACAACCATAAGAGCATCTACCACCGCCGGCAGCGCGGCGCGCCGCAGCAGACGCAGCCGCAGAACCTCACCACCAGCCCCGACACTAAGATCAACCCGCAGCATCACAACATAGACTTCTACAAGTTCAAAGACCAGTTCAACGTCTAA
Protein Sequence
MVDTQHFCLRWNNYQSSITSAFENLRDDEDFVDVTLACDGKSLKAHRVVLSACSPYFRELLKSTPCKHPVIVLQDVAFTDLHALVEFIYHGEVNVHQRSLSSFLKTAEVLRVSGLTHNENAQGPLLQPMRAPSTTSPHTPPHSAHSTHISHTPTYDRLEEALLQPATSSVQQLMRRTPLPPRRLSRSADNSPDVIKRPRHDNNNEQPQIHATDFSTKNNTHARGHNETGNNGNGISNSSSSPSPRLMDDVKNEPIDMICPSNPDIDRSTDDTPPHHHRPLGVGPPSRGSSADAEECTPPPHPPPFIQPPDSKLFNPANTYNFTMEALSHPSLTGLQSPLAPDGIASTSQVGPLGAGHRCEVCGKLLSTRLTLKRHTEQQHLQPLHSARCSLCHKVFRTLNSLNNHKSIYHRRQRGAPQQTQPQNLTTSPDTKINPQHHNIDFYKFKDQFNV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00374337; iTF_00375442; iTF_00794787; iTF_01332937; iTF_00405134; iTF_00637866; iTF_00636627; iTF_01075632; iTF_00908985; iTF_00889370; iTF_01166847; iTF_00071621; iTF_01095078; iTF_01093255; iTF_00924904; iTF_00122540; iTF_00667666; iTF_01094176; iTF_00364165; iTF_01527461; iTF_01247298; iTF_01063875; iTF_01062951; iTF_00425577; iTF_01535053; iTF_00685585; iTF_01062001; iTF_01064788; iTF_01526197; iTF_00237886; iTF_01425278; iTF_01534078; iTF_00041923; iTF_00786108; iTF_00928831; iTF_00072208; iTF_00712053; iTF_00042784; iTF_00043692; iTF_00785318; iTF_01441223; iTF_00273736; iTF_01436233; iTF_00809290; iTF_00810233; iTF_00036955; iTF_00038971; iTF_01117474; iTF_01119499; iTF_00111789; iTF_01118453; iTF_01342332; iTF_00341451; iTF_00858693; iTF_01264811; iTF_01533195; iTF_00274540; iTF_00018285; iTF_00301325; iTF_00040014; iTF_00120654; iTF_00173198; iTF_01010510; iTF_01084398; iTF_01362510; iTF_00123503; iTF_00121582; iTF_00446351; iTF_00050128; iTF_00345936; iTF_01285680; iTF_01085521; iTF_01339057; iTF_00973906; iTF_01440212; iTF_01076658; iTF_00300371; iTF_00449299; iTF_00282548; iTF_00677781; iTF_00281502; iTF_00447380; iTF_01260244; iTF_00017463; iTF_00302263; iTF_00445335; iTF_00726583; iTF_00177304; iTF_00968152; iTF_01221720; iTF_00037945; iTF_00041017; iTF_00124409; iTF_00758393; iTF_00869785; iTF_01492135; iTF_01152297; iTF_00906297; iTF_01073721; iTF_00622101; iTF_01180415; iTF_01179592; iTF_01340346; iTF_00907163; iTF_00908045; iTF_00147647; iTF_00450288; iTF_00186399; iTF_00185439; iTF_00745919; iTF_00709376; iTF_00931584; iTF_00932775; iTF_01502216; iTF_01360814;
90% Identity
iTF_00071621;
80% Identity
-