Hham002802.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hypothenemus hampei
Gene Symbol
Hr39
Assembly
GCA_013372445.1
Location
JABRWK010000120.1:121700-153424[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.64 1.1e+04 -4.7 8.6 33 168 35 163 13 218 0.39
2 4 5.8e-09 0.0001 21.8 0.0 1 28 310 337 310 345 0.86
3 4 0.012 2.1e+02 1.0 0.0 77 116 359 400 332 422 0.67
4 4 5.6e-74 9.7e-70 236.0 0.2 205 408 441 639 421 639 0.96

Sequence Information

Coding Sequence
ATGAGTTGGGAAGGAGAACTTAGTGACGGAGAACGTGATGGTATGTGTATAGATGAAAGTAGCGAATCAGCAGCACACCTTCCAGAAAATCTGTCAGTATCAGCTTCTAAACAAACTTCGACTTTTGACCTTAAAGACAGTCCAATTTTAAGGATAAAACAGCCACCAGTTAGTAGTTATTCCTTACACAGTACACCCTCCAATTCGCCTTTGTTGAATCAAAGGCATCCGGCAACTGTAGCGCCAATTATCAGCCATAAGgatCTCATGCACAAGGCGCTGAACGTTCCGCCCACACCTAGTCCGGATTCAGCCGTTCACTCCGCCTATTCGGTGTTCAGTTCGCCCAATCAGAGTCCGTTGACGCAACGTCACGTGACACTAACACCCAATCTAAGCAGAAATAATTCGGACGCCTCCCATTCGAGTTGCTGCAGCTATTCTAGCGTGTCAGTTTCTGTATCTCCCACACAACAGTTCAGCCCTACACATAGTCCAATACAGgGTTGCCATATACAAAACTCTTTGCACGGCAGTCCATTGCACCATGGTGTTCTCTATAGAAGTCATCCAGAAGACAGCTCAGCCCATCAGACTCAATACGAACAAAAATACGAACCAGACCCAGGTAACGAGGAAAGTGACGATAAATCAGGTCTGCTTCACGCTACCCTACCAGCCCAACCAGGAATTTCCagACAACAATTGATAAACAGTCCGTGTCCCATTTGTGGGGATAAAATCTCCGGGTTCCATTATGGTATTTTCAGTTGCGAGTCCTGcaaaggtttttttaagaGAACTGTACAAAATAGGAAAAACTATGTGTGTCTGAGAGGGGCGCAATGTTCAGTAACAGTTGCCACAAGGAAAAAATGTCCTGCATGTCGTTTCGATAAATGTCTTCAATGTGGTATGAAACTTGAAGCGATAAGAGAAGATAGGACTAGAGGTGGCAGGTCTACTTATCAATGTTCATACTCTTTACCTCCAAACTTAGCGTCCCAAAGTGAACTGAGGACGAGTACAACAGATTTAagACAAGGTTTAGGTGATCACCATCCGGGATTCACGATAAAATTAGAGCCTGCTGATGGTATGCAGTCGTATcataaaagaaacaatttgcCTGGATCGAAAGGTGTCCCGCCATTATTGCAAgaaATAATGGATGTGGAGCATCTGTGGCACTATAACGAAATggaattgaataaattaagtaCCGAAGGCCACTTGGGCAAAGAGGGTGCCTCAGGAGCCGTCCACAATCTGTCTAATCATCCCCTTTTGGCCGGTACCGCCCTGGCGGGGTCCACGGACACGAATCCGGACTTTATCGCCAATTTGTGCAATATAGCCGATCATCGACTTTATAAAATCGTTAAATGGTGTAAAAGTCTTCcattatttaagaatatttcgATTGACGATCAAATTTGCCTATTAATAAATTCGTGGTGCGAGCTACTTCTGTTTTCTTGTTGTTTCCGTTCAATGTCTACTCCCGGTGAGATTCGTGTGTCTTTGGGGAAAAGCATTACTGCCGCTCAAGCCCGAGATATGGGTATGCAAGCCTGCATTGAGAGAATGTTGAATTTCACCGAACAACTCAGAAGATTAAAAGTCGATCAGTACGAGTACGTAGCCATGAAAGTTATCGTTTTATTAACTTCTGACACTTCCGAGCTTCGCGAAGCTGAAAAAGTGCGAGTGTCCCAGGAAAAGGCTTTAAAAGCGTTGCAAGATTATACGTTGTCGCATTATCCACAAAGTCCAGCGAAATTTGGAGAATTGCTTTTAAGGATTCCTGAGTTGCAACGAACGTGCCAGGTAGGAAAGGAGATGTTAACTATAAAATCGAAAGACGGGGATGGTCCAAGTTTTAATCTTCTTATGGAACTCCTGCGTGGAGATCACTGA
Protein Sequence
MSWEGELSDGERDGMCIDESSESAAHLPENLSVSASKQTSTFDLKDSPILRIKQPPVSSYSLHSTPSNSPLLNQRHPATVAPIISHKDLMHKALNVPPTPSPDSAVHSAYSVFSSPNQSPLTQRHVTLTPNLSRNNSDASHSSCCSYSSVSVSVSPTQQFSPTHSPIQGCHIQNSLHGSPLHHGVLYRSHPEDSSAHQTQYEQKYEPDPGNEESDDKSGLLHATLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAQCSVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPNLASQSELRTSTTDLRQGLGDHHPGFTIKLEPADGMQSYHKRNNLPGSKGVPPLLQEIMDVEHLWHYNEMELNKLSTEGHLGKEGASGAVHNLSNHPLLAGTALAGSTDTNPDFIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITAAQARDMGMQACIERMLNFTEQLRRLKVDQYEYVAMKVIVLLTSDTSELREAEKVRVSQEKALKALQDYTLSHYPQSPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01240932;
90% Identity
iTF_00830497;
80% Identity
iTF_00830497;