Basic Information

Insect: Hyposmocoma kahamanoa
Gene Symbol: Hr39
Assembly: GCA_003589595.1
Location: NW:5578602-5621233[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.49 2.1e+03 -2.7 0.3 119 128 112 121 51 226 0.53

2 5 3 1.3e+04 -5.4 7.6 97 163 266 333 186 378 0.58

3 5 8.8e-08 0.00039 19.5 0.1 1 20 468 487 468 493 0.91

4 5 0.0084 37 3.1 0.0 76 123 512 556 488 582 0.76

5 5 4.6e-44 2e-40 139.0 0.0 164 328 529 699 516 704 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.49	2.1e+03	-2.7	0.3	119	128	112	121	51	226	0.53
2	5	3	1.3e+04	-5.4	7.6	97	163	266	333	186	378	0.58
3	5	8.8e-08	0.00039	19.5	0.1	1	20	468	487	468	493	0.91
4	5	0.0084	37	3.1	0.0	76	123	512	556	488	582	0.76
5	5	4.6e-44	2e-40	139.0	0.0	164	328	529	699	516	704	0.81

Sequence Information

Coding Sequence: ATGGCGACGGCGGGCGGACAGCGGGTGGCGGGCGCGGGGTGCGGCAGCGTGCATTCACCTCTGACCCGCGCGCGGGGCGAGCGGCGCTCAAGGTCGGTGCGCCGCCTGAAGGTCGCTCCTCACGTGACGCCGAGGGTGCTCAACCCTCTGCGCTCCGCCATCCGCCGCCAGTTCTCGTACAGCTCTAGTGGAGTTCGAATCAGCGTGTCTTCAGAGCCTCACGACGAGGACTCCACTGACGCCGAGATCTCCAAAATCGACTTCTCACAGCACCAGTACGAGGTAAACATGCGAAGCAAGAAGAAGCGGTCGTCGAGTGGCACGCAATGCGATAGCCAGAGCAACGATCGCGAGCGCCCTATGTCCTGGGAGGGGGAGCTTTCTGATTCTGAAATGGTCATTGATACTAGTGTCAATAATGATGAAAACAGCAATTCCCTCGACCTCCAATCATCCCGCGATTCCATAGACACACTTCGCAACGTGACCATCAAGACAGAACCGCTCAAGACCGAGCCCTTTCAGAGCCTGGATGACCAGAGGGTGCTCGACTTGAAGTACACAGCGCCACTGCAACCGCATCAGAGAAGTCTTAGTATGAATAGAaTATCGGTTCTAACAGACAACGCGACCCTTTCCCTCCCTCGACGGCCTTCTCCGCCCACCAGCACCGCCAAGTCCTTAATCCTGGAGCAGGGTACAGTGCCAATGATGACACAGGCTACTGGTGAAGTCCAGAACTTGACTATTAAGAAGGAAACTCAGTTGTCGGAGCTGAAATGTGAGCCGTCAGTCGGCATGGACAAGCTGCTCGGCGCGCTGCACGGGTCTCCCCTGCTGGGGCGTTTGCCGCGCGTGCAATCCAGCGCTAGCACCGACTCCGCCGTGCACTCAATGTACACTCACAGTGTCTACAGTAGTCCATCGGCAAGTCCCCGCGCGTCGCGACACTACACGCCGTCACTGTCCCGCAACAACAGCGATGCTTCACACTCCTCCTGCTACTCTTACAGCTCCGAATTCTCGCCTACGCATTCTCCTGTTCAGggTCGACACCCACATGTGGTATACCGCGAAGCGACTGCCGGCGCGGTATTTCCTGCGTCGCCCGCTCACGACGAAGACGCGGAAACAGCTGACGAGCGACTGCATCACCATCAGGGCATTAGCCGACAACAGCTGATTAATAGTCCGTGCCCAATCTGCGGCGACAAAATCAGCGGGTTCCACTACGGCATATTCTCGTGCGAGTCTTGCAAGGGCTTCTTCAAGCGAACCGTGCAGAATAGAAAGAACTATATGTGTCTACGAGGCGGAAATTGTCCCGTTACGGTAGCCACTAGAAAGAAGTGCCCTGCATGCCGATTTGATAAGTGTTTAGGATGTGGAATGAAGCTTGAAGCGATCCGAGAGGACAGGACACGTGGCGGTCGGTCAACGTACCAATGCTCGTATTCCCTTTCGGGTGCATCGTCTACGGGCTCTCTCCTTTCCGCACATGTCCCTACTACTCTACGGCATGCTTCCAGTCTTACTTGTGTAAATGGCCCAGGTTCATATAGCCGAGGAGAATCCAGTAATAGTAGACTAACTCCTGACATACCTCCGTTATTACAGGAAATAATGGACGTAGAACACCTGTGGCAATATAACGAGTCCGAATTGAAAAACCTTGGCAAATCAACGGGAAGTCCGTCTGCCAACCCACTCTTAGCAGCCAGCGGCATCACTGCTCAGAACTCGAGTCCTGACTTTCTCGCGGACCTGTGCAATATTGCGGACCACCGGCTGTATAAGATCGTCAAGTGGTGCAAGAGTCTGCCACTTTTTAAGAATATTTCCATCGACGACCAAATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCTTGCTGCTACCGCGGCGTCGGCACACCTGGAGAGGTGCGGGTGGGTGGAGGACGCGGTATCACGCTGCATCAGAGTGCCAAATTGGGCTTAACGCCTTGCATAGAACGAATGTTGACGTTTACCGACCACCTTCGACGATTGCGAGTCGACCGATACGAATACGTCGCATTGAAAGTTATTGTGCTGCTCACGTCAGGTAAAAAATATcagaattaa
Protein Sequence: MATAGGQRVAGAGCGSVHSPLTRARGERRSRSVRRLKVAPHVTPRVLNPLRSAIRRQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFSQHQYEVNMRSKKKRSSSGTQCDSQSNDRERPMSWEGELSDSEMVIDTSVNNDENSNSLDLQSSRDSIDTLRNVTIKTEPLKTEPFQSLDDQRVLDLKYTAPLQPHQRSLSMNRISVLTDNATLSLPRRPSPPTSTAKSLILEQGTVPMMTQATGEVQNLTIKKETQLSELKCEPSVGMDKLLGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREATAGAVFPASPAHDEDAETADERLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGASSTGSLLSAHVPTTLRHASSLTCVNGPGSYSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELKNLGKSTGSPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGGRGITLHQSAKLGLTPCIERMLTFTDHLRRLRVDRYEYVALKVIVLLTSGKKYQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00033911;
90% Identity: iTF_00806824;
80% Identity: iTF_00828048;