Basic Information

Insect: Hypomecis punctinalis
Gene Symbol: Bcl11b
Assembly: GCA_949316475.1
Location: OX438794.1:23367465-23389058[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.94 1e+02 5.0 1.4 2 22 163 183 162 183 0.93

2 12 0.029 3.2 9.7 0.2 2 20 197 215 196 217 0.96

3 12 0.0038 0.41 12.6 1.3 1 23 258 280 258 280 0.98

4 12 0.36 39 6.3 0.4 2 20 382 400 381 402 0.89

5 12 0.0003 0.033 16.0 1.9 1 23 410 433 410 433 0.97

6 12 0.00046 0.05 15.4 1.9 1 23 455 477 455 477 0.98

7 12 1.8e-06 0.0002 23.0 2.1 1 23 484 506 484 506 0.98

8 12 5.1e-07 5.6e-05 24.7 1.7 3 23 520 540 518 540 0.96

9 12 1.1e-06 0.00012 23.7 0.5 1 23 546 568 546 568 0.99

10 12 5.6e-07 6.1e-05 24.6 2.5 2 23 575 596 574 596 0.96

11 12 1.9e-07 2.1e-05 26.1 1.5 1 23 602 624 602 624 0.99

12 12 1.1e-05 0.0011 20.6 0.1 1 23 630 652 630 652 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.94	1e+02	5.0	1.4	2	22	163	183	162	183	0.93
2	12	0.029	3.2	9.7	0.2	2	20	197	215	196	217	0.96
3	12	0.0038	0.41	12.6	1.3	1	23	258	280	258	280	0.98
4	12	0.36	39	6.3	0.4	2	20	382	400	381	402	0.89
5	12	0.0003	0.033	16.0	1.9	1	23	410	433	410	433	0.97
6	12	0.00046	0.05	15.4	1.9	1	23	455	477	455	477	0.98
7	12	1.8e-06	0.0002	23.0	2.1	1	23	484	506	484	506	0.98
8	12	5.1e-07	5.6e-05	24.7	1.7	3	23	520	540	518	540	0.96
9	12	1.1e-06	0.00012	23.7	0.5	1	23	546	568	546	568	0.99
10	12	5.6e-07	6.1e-05	24.6	2.5	2	23	575	596	574	596	0.96
11	12	1.9e-07	2.1e-05	26.1	1.5	1	23	602	624	602	624	0.99
12	12	1.1e-05	0.0011	20.6	0.1	1	23	630	652	630	652	0.99

Sequence Information

Coding Sequence: ATGGCTGCTCACCATCACAAcaaagttgaaattaaaatcgaaaaattatGCCGCACATGCCTATCGCGCGATAACGAATTGAATTCGTTATTCGAAATTACTGTTGGATCTGTATCTCTGGATGCAGTAGTAACTGCTATAACTGGGCTTAAGATCCGTAAAGGCGATGGACTACCTTCCACAATATGTAGCGAGTGCAAGGATAAAGCAGAAAAAGCTTACGACTTTAAAAAGAAATCACAGGAAGCACACATTTCTTTAAGAGGCTTTTTCAAGAAAGACAACACGGTACTGCAGAAAACAGAAGATGTCAATAATAAAgagAAAAAGCCAATGGATGTCAAAACTGAACACTTTTCAtataatgacaatgatgatTTTTCTGATGCGGATTATAGTTTTCCGCTAAGTAATAATCCAGATGAGTCTAGTAATTTAGaaGTCAATGTGAAACATGAAGAATATAAAGAAGAAAATGTATACATCGAATGCAAGAAGTGTTGTTTGGTATTCGATACTGCTAGTAAATATGAagaacataaaagaaaaagatgTGTAAAAGTTGAATTTGAGGATGTGAATGGAACATATTGTCCGATTTGTGGCACCTGCTATGATGGGGACCAAAGTCTGTCCAAGCACATGTGGGAGTTCCACGCTGACTTGATGGGCCCCAAAAAAAGGGGACGGCCTAAAAAACTCATGACAACGacaaTATTAAACAAACTGTCTGAAAATGGTCTACTAATTTCATCGAGGCAAAAGAAGACGTACCAGTGTTCCTTTTGTAAAGTCCAAACTAAAACCAAAGAAGATTTAAGTTCTCATATTTTGCAACataaagATTTAAAAGTGTTATGCTGTATTGTATGcaagaaaatgtttttgaaaaagaagtttttcaatTTTCATGCTTGCAACAGAAATTCCACTAATGCCATTGataatGATTCATCAAATTCCCAAGGAGAAAAGAACGGAAAGTCAGCATACTCCACAGAGATGCTTTTGCAGGAGCTGTTCGATCCAAATGGAGATATGGCATTGACTATGGTTCAAGCGTGTACAGCGTGCTCCGGGGTCTACCTTTCTGAAGCTGATCTCATCAACCACCACGACACCGAGCATCCAGAGCTCTCTCTCAGGTGCAACCATTGTACAAAGtTATTCGCATCAGTTAAGACAGCGGCGCGTCACAGATCCGTATGTAAGCAGATCGAGAGAATGCACAAGTGTACCACATGTGGATTAAAGTTCGCGTACGAAATTTCTCTCAACAAACACATATTGCGATACCATCAGGGGGAAAGTGTCTCTGTTGCTTTCATGAGCCGGAAGCACAAAGTTGAAGAAAATGTACAGTATCAATGCGACACGTGTCACAAGATGTTCCTTAGGAAAGATGCTCTTGCGAAGCACGCTAAGCTGCACATGCCAAATCAGAAGCTTTTTGAATGCGACGTCTGTCAAAAGAAGTTCAATCGCAGTGATAATCTACGAACCCACAAGAAGATACACGACGTGGACAGAGTGAAGCCGCCGGCAAACAACTGTCTCTGCCTCTACTGCGGTCGAGGGTTCTCCAACTCTTCCAATCTGATCGTCCACATGCGCCGACATACTGGGGAGAAGCCTTATAAGTGCGACTTCTGCCCTAAAGGTTTCCCGAGGTCATCAGATCTTTTGGTCCACAGAAGATCGCATACAGGCGAAAAACCTTGTGTTTGCCGCATTTGTGGCAAAGCGTTCTCCCGTAGCAACAAGCTGTCGCGACACATGCGCGTCCACACGGGCCAGCGGCCCTACAAGTGCACGTATTGTGAGAAGGCATTCTCTCAGAGCAACGATCTGACCCTGCACATCCGGCGGCACACCGGCGACAAACCTTACGTGTGTGAAGTGTGCGGCGAGAGGTTCATACAGGGTACAGCTCTGCAGAACCACAGGCGGACGCACGGGCACtttccgccgccgccgccagaCCTGGCCTCCCTGACTAGCCAGGTCCAAGCCATCACCTACACAGTCTCCAATATTTCCAACATCTCCAACATTAATCTACCATCACACGAGACTCACATGCCCAACTAG
Protein Sequence: MAAHHHNKVEIKIEKLCRTCLSRDNELNSLFEITVGSVSLDAVVTAITGLKIRKGDGLPSTICSECKDKAEKAYDFKKKSQEAHISLRGFFKKDNTVLQKTEDVNNKEKKPMDVKTEHFSYNDNDDFSDADYSFPLSNNPDESSNLEVNVKHEEYKEENVYIECKKCCLVFDTASKYEEHKRKRCVKVEFEDVNGTYCPICGTCYDGDQSLSKHMWEFHADLMGPKKRGRPKKLMTTTILNKLSENGLLISSRQKKTYQCSFCKVQTKTKEDLSSHILQHKDLKVLCCIVCKKMFLKKKFFNFHACNRNSTNAIDNDSSNSQGEKNGKSAYSTEMLLQELFDPNGDMALTMVQACTACSGVYLSEADLINHHDTEHPELSLRCNHCTKLFASVKTAARHRSVCKQIERMHKCTTCGLKFAYEISLNKHILRYHQGESVSVAFMSRKHKVEENVQYQCDTCHKMFLRKDALAKHAKLHMPNQKLFECDVCQKKFNRSDNLRTHKKIHDVDRVKPPANNCLCLYCGRGFSNSSNLIVHMRRHTGEKPYKCDFCPKGFPRSSDLLVHRRSHTGEKPCVCRICGKAFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLTLHIRRHTGDKPYVCEVCGERFIQGTALQNHRRTHGHFPPPPPDLASLTSQVQAITYTVSNISNISNINLPSHETHMPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00044719;
90% Identity: iTF_00826062;
80% Identity: -