Hato011537.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hypomecis atomaria
Gene Symbol
IPP
Assembly
GCA_964007245.1
Location
OZ023286.1:11925094-11936829[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.3e-29 3.5e-26 92.7 0.0 5 108 33 134 29 136 0.95

Sequence Information

Coding Sequence
ATGAATTCTTTTGATAGACCTGCAAATAAAGATGGTTCTCGCACATACAAATGTCATGAATACACGAACAAAATATCTTCACATTTACTGCTCCTCAAAAGGGATGGAAGGTTTTGTGATATAGAATTAATATCAGGAAATACTAAAGTTAAGGCTCATCGTGTAGTATTGGCAGCTAGCAGTGAATATTTTGATGCTATGTTTAGTGTGGGATTAGAAGAAAGCCTTAAAGACCATGTAGAACTGCCCACAGTGCCACCTGATATATTGCCAAGGATAATAGACTTTATATACACAGGAGAAGTAGTTATTGATAAACAAACAGTACAACATTTACTAATAGCTGCTGATATGCTGCAGCTAAGTGAGCTGGTGTCAGGATGTGGAGAATTCCTTAAAAGAGAACTGCACCCTTCCAATTGTTTAGGTATTTACAGGTTCTCGGAAGCACACAACTGCACTGAACTTTCAAAAGAAGCATTGGAGCATGCACAAGCAAACTGGAATGTAGTGGCTCATGGGGATGAGTTGTTGGAATTGCCCCTGCCGCAGCTGGTCACCCTCTTGTCTTCTGAACAGCTGAAAGTGGATTCAGAGTCTCAGGTGTTATATCCAGCCTTGAGGTGGCTGGAACACGACTCGATAGGGCGCAGACGGCATTGCTTTGAAGTGTTGAGCCATGTTCGGCTGCCTCTCATTCCGCCTGAAGTTTTAGATGAAGCAATAAAGGGTGTAAAAGATCCATCGTTAGCTGTCGCTCTGAAAACTGTCCGAGTCGATATGAAGAGCGGTCGCGGCGCGCTGGTGCCGCTGGGCGCGGTGCCGCGCGCGCGCGCTCGCCGCGTGCTGCTGGTGGTGGGCGGCTCGTGCCGCGACAAGGCGCAGCCGCCGCTCGCCACCGACAACTACCTCTCCTCCGTGCTCAAATACGACGTCCACAACAAGGAATGGGAGGAGTTGGCTCCGATGGCGATAGAGCGGATCCAGCCGGGAGTGGCCATGCTGGGCGGGCGGGTGTACGCGGTGGGCGGCGAGCAGGGCAGCCAAATACTCGCTAACGGGGAGTGCTACGATCCACAGACGGACAAATGGAGCGACATCGCAGCGTTACACGAGGCGCGGTGCGAGTTCGGTATGACGACGTGGAACGGGCAGCTGTACGCGCTCGGCGGCTGGGTGGGCTCCGACATGGGCGCCTCCGTCGAGGCCTACGACCCCTTCACGGACGAGTGGACCATCGTGGGCCGCATGCCCGAGCCGCGCTTCGGGATGGGCGTCGTCACCTATCAAGGTCAGATCTACGTGGTGGGCGGGTGCACACACGCGTGGCGACACACGCGGCACCTGCTGCGCTACTGCCCGGCCACGCGCGCGTGGCGCGCGCTTGCGCCCATGCGGCAGGAGCGCAGCCAGCTGGCGGCCGTGGTGCTCGACCACCACCTCTACGCCATCGGCGGCAACGCGCCGCGCCGCACGCTGCTCGCGTCCGTCGAGCGGTACAGCTTCGATGACGACTCGTGGGAGGAGGTGTCCCCGATGCGCGAGGCGCGCGCCGGCatggcggcgggcgcggcggacGGCGCGCTCGTGGTGGCGGGCGGCGACGGCGAGTCCGCCGGCGGCGGCGCCTTCTACTGCGCGCGCACCACGCTCGCCAGCGTCGAGCTCTACTGCCCGCGCGACAACGCCTGGCGCGTCGGCCCGCCGCTGCCGCACTCGCGCGCCGAGGCCGGCGCCGCTATGCTCTGA
Protein Sequence
MNSFDRPANKDGSRTYKCHEYTNKISSHLLLLKRDGRFCDIELISGNTKVKAHRVVLAASSEYFDAMFSVGLEESLKDHVELPTVPPDILPRIIDFIYTGEVVIDKQTVQHLLIAADMLQLSELVSGCGEFLKRELHPSNCLGIYRFSEAHNCTELSKEALEHAQANWNVVAHGDELLELPLPQLVTLLSSEQLKVDSESQVLYPALRWLEHDSIGRRRHCFEVLSHVRLPLIPPEVLDEAIKGVKDPSLAVALKTVRVDMKSGRGALVPLGAVPRARARRVLLVVGGSCRDKAQPPLATDNYLSSVLKYDVHNKEWEELAPMAIERIQPGVAMLGGRVYAVGGEQGSQILANGECYDPQTDKWSDIAALHEARCEFGMTTWNGQLYALGGWVGSDMGASVEAYDPFTDEWTIVGRMPEPRFGMGVVTYQGQIYVVGGCTHAWRHTRHLLRYCPATRAWRALAPMRQERSQLAAVVLDHHLYAIGGNAPRRTLLASVERYSFDDDSWEEVSPMREARAGMAAGAADGALVVAGGDGESAGGGAFYCARTTLASVELYCPRDNAWRVGPPLPHSRAEAGAAML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00125225;
90% Identity
iTF_00206210; iTF_00033029; iTF_00044621; iTF_00827122; iTF_00926739; iTF_00634614; iTF_00207098; iTF_00143167; iTF_00666655; iTF_00650149; iTF_00635530; iTF_00896052;
80% Identity
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