Basic Information

Insect: Hyphantria cunea
Gene Symbol: IKZF1
Assembly: GCA_003709505.1
Location: PKRV01000652.1:1416074-1427791[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 2 1.3e+02 3.4 1.0 1 23 55 78 55 78 0.95

2 21 0.037 2.3 8.9 4.4 1 23 85 108 85 108 0.97

3 21 9 5.6e+02 1.4 4.3 1 23 197 219 197 219 0.97

4 21 0.0016 0.097 13.2 1.0 2 23 225 246 224 246 0.97

5 21 6.1 3.8e+02 1.9 3.1 1 23 252 274 252 275 0.94

6 21 0.16 9.8 6.9 3.8 2 22 511 531 510 531 0.96

7 21 0.078 4.9 7.9 2.6 1 23 630 652 630 652 0.95

8 21 0.54 34 5.2 0.3 2 23 791 812 790 812 0.96

9 21 0.011 0.67 10.6 0.6 2 23 889 910 888 910 0.96

10 21 0.024 1.5 9.5 0.6 1 23 918 940 918 940 0.98

11 21 0.14 8.8 7.1 3.2 1 23 974 996 974 996 0.95

12 21 0.00022 0.014 15.9 4.0 1 23 1004 1026 1004 1026 0.99

13 21 0.068 4.3 8.1 3.0 1 23 1112 1134 1112 1134 0.98

14 21 1.9 1.2e+02 3.5 2.3 1 23 1187 1209 1187 1209 0.92

15 21 6.9 4.3e+02 1.8 0.1 2 23 1216 1237 1216 1237 0.94

16 21 0.031 1.9 9.1 0.5 1 23 1304 1326 1304 1326 0.94

17 21 0.0089 0.56 10.8 0.7 1 23 1332 1354 1332 1354 0.95

18 21 0.0061 0.38 11.4 2.6 1 23 1444 1466 1444 1466 0.97

19 21 0.00015 0.0095 16.4 1.4 1 23 1472 1494 1472 1494 0.99

20 21 0.3 19 6.0 2.9 1 23 1585 1607 1585 1607 0.96

21 21 0.0026 0.16 12.5 3.7 1 23 1618 1640 1618 1640 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	2	1.3e+02	3.4	1.0	1	23	55	78	55	78	0.95
2	21	0.037	2.3	8.9	4.4	1	23	85	108	85	108	0.97
3	21	9	5.6e+02	1.4	4.3	1	23	197	219	197	219	0.97
4	21	0.0016	0.097	13.2	1.0	2	23	225	246	224	246	0.97
5	21	6.1	3.8e+02	1.9	3.1	1	23	252	274	252	275	0.94
6	21	0.16	9.8	6.9	3.8	2	22	511	531	510	531	0.96
7	21	0.078	4.9	7.9	2.6	1	23	630	652	630	652	0.95
8	21	0.54	34	5.2	0.3	2	23	791	812	790	812	0.96
9	21	0.011	0.67	10.6	0.6	2	23	889	910	888	910	0.96
10	21	0.024	1.5	9.5	0.6	1	23	918	940	918	940	0.98
11	21	0.14	8.8	7.1	3.2	1	23	974	996	974	996	0.95
12	21	0.00022	0.014	15.9	4.0	1	23	1004	1026	1004	1026	0.99
13	21	0.068	4.3	8.1	3.0	1	23	1112	1134	1112	1134	0.98
14	21	1.9	1.2e+02	3.5	2.3	1	23	1187	1209	1187	1209	0.92
15	21	6.9	4.3e+02	1.8	0.1	2	23	1216	1237	1216	1237	0.94
16	21	0.031	1.9	9.1	0.5	1	23	1304	1326	1304	1326	0.94
17	21	0.0089	0.56	10.8	0.7	1	23	1332	1354	1332	1354	0.95
18	21	0.0061	0.38	11.4	2.6	1	23	1444	1466	1444	1466	0.97
19	21	0.00015	0.0095	16.4	1.4	1	23	1472	1494	1472	1494	0.99
20	21	0.3	19	6.0	2.9	1	23	1585	1607	1585	1607	0.96
21	21	0.0026	0.16	12.5	3.7	1	23	1618	1640	1618	1640	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGAGCGCACAAGTCGGCGAGGTCGCGACTCTCTTCGGGCGCTACCTTGAAGGCCGTGCCGGTGGAGACGTCTCTTCAGAAGCCTCCTCTGACGCCGCTGAAGATTTAGAGTTACCACAGTGTAAAATAAGAAGGAACTATAATTGCACAAAGTGCACTTTTTATACGCAGAACCCACGGGCCTTTCTCGTTCACACGCGAGACGCTCACTTtgtgaaattgaaaattttcgaTTGTCCACATTGTGTTTACGCATCCAAACATCACCAAAAACTTATAAGACACATAAAAATGGTTCACGAAGAAGTTGTAACACGAACTCCAAAGTCTAATTCATCAGCGAAATTAGATGTTGAGGTACCCAACTCCACACACGATGATCAATGTATGCGTATAGAAGATATGTTAGAAGAAGTCGAAGACTGTGAAGATATGATGATAGAAGTTGAAGAAGGACCCGACTACTCAATGGAACAAGTGGACGACATCGACGCCGTCGACGACTTAACCACAGAACATGCAGCGCCCTCAAAcctattaaaaacaaagaataacGTTAAGTTTTTCACATGTGATAAGTGCACCTATGTTACCCACATAAGAGCTAGATTTACTAAACACGTCAAATATCACTCTATGCCTATGATCAAGTGTACTATGTGTGACTTCCGGACACCGTATAAGTGGAACTTAGACCGGCACATGAAGAACCATGGTGGGAGCGGAAGTTTTCATTGCTCCATGTGCAACTTTACTGCAGACATCAAGCAGAGTCTGACGGTTCACGAAATGAATCATCACACACCGCCAGCGGGTCAATCGCTGTCGGGTCGTCGACGCAACCGGGTGGGTGCCAGCGACACAGTTATCGCCGAGCACGACGCAGCGAATGTGGCGCTCCCCAAGGATGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGAAATGGGTCTACAATACGCTGACAGAGAAATAGTTAGCTGCAAAAGCGACTCTAATGATGGTTCGCCCCCAGACGCTTCGGAAAAAAGGGACAGTCAAAGTTCACCCAACCATAGTTCAGATGagtctaaacaaaaaaataacagaaaaattcCACGACCAATACCGCAACTCATACCATTAAATTCCTCAGCACCCAATCAGAAGCAAACAAATACCGGTGAGCCACCACAAAAGAAATTCAAGGAATCATCACCCGTGGACTTAACTGACACGAAATctgataaaatagaaaatttgcCTACTGATATATCTTTATTTCCGATCAATAATTCATTAAGTAAAGAGGTCGGTGGACGCAAGAAAAATGAATCCTTCTTTGATAGACTTAAGGAGCGGCTGCTTGCTGAAACTGGAGAAGAAGGTTCTCTTGTATGCAAAAATTGTGGATTTGAAAGTAAATGTTTATCAGAACATTCAGTGCACGAGAAAAATTGCTCACCACAAGCTAATCGAACGACTGCAAATGCATCGCATTCAAGTTTAAGTTCTACACGATGTCAAAATTGCAGACATAGATGTAAGTCGAGTGCAGACTTATATGTTCACATGAAAACGTGCGCTAAAAATTACAGAGTTGAAAACgataatatttgcaaaaataaaaacgagGACAGCAAtgacactactactactaatcaAGAGAAGGAGTTAGAGCGCCATCCCATGGAAAATGTTGTCTTCGTTTGGAACAATATTGATCAAGATACCAACAAATTTGACACTCCTTTAGGTATCAATATAAACGACGACTCTACTTTACCGGGACCAAACCGGAGCTTTGATGTAGAGATTATCGACGAAAATGAGAGTATGAATTTATCACCAAGTCAAGCAGTCGGGAGAAAAGTATTTAAGTGTCCTCACTGTCCATTCTTCTCCACAACCGCGTCGAGATTTCATGTCCATATTGTTGGCCACTTGAACAAAAAGCCCTTCGAATGttctttatgtaaatataaatcaaactGGAGGTGGGATATTACGAAACATATAAAACTCAAGTCTGCAAGAGACCCGGAACACAACGATGCTAAGGTATTAATGACCGATGAGACAGGGAGAAGGAATTATAGCAAGTATAACAAATTCTTGGCAATGCCAGTATTGAACGAGTATGGAGAAAATGAGTTCCACTATTTGGATTGTAACACATCGATAGATGGATCCATGGAAATTGATGATTCATTCCATGACATGTCAGATGTTATGAGTGAGCATTACGAAATGCAACCACTGAATCTGCAAACTCAGTACGGTGACGAGAAGTATGATTTGCTTGATAGCAGAGGTCTAAGTTTCAATGATATGAAGAAACCGAAGAAAACTCTGTGGAAATGTAAGAAATGTAATTACAAGGATCCGTCAAAAGAAGCTCTATTGGAACACGTTCGTGAACATTCTAAGGACGGAATACAAGAAGAACCGCTGAAATCTGCCGGCTCTAAGAAATCTGAAAACACTCCCGATCCAGCTGACTTGGCCTATCGTTGTGGCCACTGTCACCAACTCTCCAATTGGAAACATGTTATACAGAGACACTGCCGTTTGAAGCATGATGGTGTCATAAAAGTTATAACAACAGTGAAGCCAAAACCAGACCCCGTGAGCATAAATGACATTAACGACACCTGTAATAAATGTCCCTTCAGATCAAACGATAAAAAACTGCTTATTGCCCATCTGCAACAACATCAACCATCACCGCAATCagtatttaaatgttacttCTGTCCTTACTTTGTCAAAGATGAAAACGAGCTGTCGCAACATTTGCTTGTACATGGCATCACGGAGCCTGAAGATTATATTTCAAAAGCTATGGAAGAAAAATCACCTTTACAAGAACAGCAATTGAATCCCTCATCGTGTTCAACAAAACGTCATAGATGTACAGAATGCCCATATGAAACAAATAGCAAGTCCCAATATATGTACCATGAACAATTTCACCGTACACCATCCGACACACCATACAAATGTCCAGAGTGCAACTACAGTGTGTCCAAGAGACATCTATTGCACCAACATTTAAGAGTTCACggaataataacaaaaaggtTGGATGTGGAATATGGTTTAGATCAACCATCAACATCGCAGAACAAAAATGATGGTAAAATCGATTCTGAAGGcatattttatgaagaaattcCATATGTATGGGTGTCTGCTAAGAACGAGTTCCATAAAATGTACAAATGTCGATATTGTTCATACGTCAATTCCATTCAATGCAAAATTCCAAATCACGAAAATCTCcatttcattgtttttgaaaataatgacaCAACGATTTACAAGTGTCTGGAATGCAAATTTACTTGCAACAATGCTAGTAGGCTTGCAGAGCATTCTAAAAGCCATGGAGAAATATATGGTCGGATTTACTGTCCTGTTGAAAATGACAGTCCTGATGAGCAGCAAATTGCAAAGTTAAGAAAAGTTATTGAAATGGATAAAGGCACAGAAAACTTTTCTAAAGAAGAAGGCGTAACTGAGAGCAGAGAGATCAAAATGTTATACTTCTGTCACATGTGTCCAGCTAGGTTTTTTGAAGATACTGAATTAGAAAGTCACAAAACATTCCATAATGCCACATTGCCAAATAAATGTACTAGCTGTGAGTATTCGGTATCTGAAGGAAATGATTTAGCAGCTCACGAAACAGTGCACACAGATGAATAtcacacaaaaactaaaattctaaaatttcttCATAATTTACATCCAACTCACAGGCAGCCTCAGTTGGCAATGGCACCTGATTCTACCGATTCCGAAATCAAATGGATATCTATCGGTCCACCAAAGGCTGAAAACGTtgaaagtaatgtaaaaaaatcgcATGATACAAAACATGTGCCAAAGCAATACTTTTGTAAGCTATGCCCTGCAAAATTCTTTAAAAGTTCAGCTCTAAACTATCATGCAGCATTACATGGAGGAGATGGTGACCATAAATGCAAGACATGTAATTATGCTGTTAAAAACATAGGCAACCTTGCTAAACATGAGATTttacatgaaaagaaaaataaacccTCAAATTGTGACTATGAGTCTGGTGAAGATATGGATTATAAGAATGTTCCATTATCAGGCACAGATTTGTTCCAGAGAAAGACTGAAGCTCAGAAAAGAGTGTTAATAGACAAAGATAAATTAGTTAAGCCAAATGATCATTTTCCGCCTGTCTTACAAGCCGACCCGCAATTCGGGTACTTGATGCACGGTAATCCTGAATTTATATATCCCACTTATCTGAAAAATGGCCGACAAAAAGAAAAGCGTTATAAGTGTCATAAATGTCCCTCAGCATTTGAGAAACGAgaacaatataaaattcatcTTTCGTTGCATGGTTCCAAGCAAAGATATAAATGTGAGTTATGTGATTATTCCGTGAAATATTATGCTAATTACGTGCAACATATGAGGAAACATCAAATGAACGATGAGGCGCAAGcagaaagaaagaaaggtaACAATGGTTTTGTTATGGCTGAAAACCAAGACTTGAACAAAGATGAAAGCACTGATAATATTAAGCTTGCAATTAAAACTATGCCAAAGGGACCTCCGAAAAGCGATTTCCAACAATTCTCTATAAGTGACCAACAAACTCTTCGACTGCTACAACGGAGAAGATCTATAAATGATTGTGCAAAGGATCTTAATACGAACGAAACTTCTCCAACCAAAGAACGTAAGATGCACATGTGTTTATTGTGCCCCTATACCAATCAACGCCAGGATTCCTTAACAAACCACTATAGGCGACATGGTGACACAGACGCTTTAACTGCCACAAACCATAAATGTTCTTATTGTGATCTTGTTGTTGTACAGTCACATTTTCTTCGAGAgcatttaaaaacacatttcaatTACCACAAGACTCTTACACCTGAATGTTTCGTGGCAAATGAAGACGTTGGCTTTACGATTACTAAGATTGAAGATGACAGTAGTGAACCAGTTGATCTCAATTTAAATGTGCAAAACAAGATATTTGTCtgcaaagaagaaaaaatgtatgtaaaaattgcCACAGGTGAACTGTTGGCTGCTTGGGATTag
Protein Sequence: MLQQMSSPPSAQVGEVATLFGRYLEGRAGGDVSSEASSDAAEDLELPQCKIRRNYNCTKCTFYTQNPRAFLVHTRDAHFVKLKIFDCPHCVYASKHHQKLIRHIKMVHEEVVTRTPKSNSSAKLDVEVPNSTHDDQCMRIEDMLEEVEDCEDMMIEVEEGPDYSMEQVDDIDAVDDLTTEHAAPSNLLKTKNNVKFFTCDKCTYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFHCSMCNFTADIKQSLTVHEMNHHTPPAGQSLSGRRRNRVGASDTVIAEHDAANVALPKDEEGSGDSRSSHSVSEMGLQYADREIVSCKSDSNDGSPPDASEKRDSQSSPNHSSDESKQKNNRKIPRPIPQLIPLNSSAPNQKQTNTGEPPQKKFKESSPVDLTDTKSDKIENLPTDISLFPINNSLSKEVGGRKKNESFFDRLKERLLAETGEEGSLVCKNCGFESKCLSEHSVHEKNCSPQANRTTANASHSSLSSTRCQNCRHRCKSSADLYVHMKTCAKNYRVENDNICKNKNEDSNDTTTTNQEKELERHPMENVVFVWNNIDQDTNKFDTPLGININDDSTLPGPNRSFDVEIIDENESMNLSPSQAVGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNDAKVLMTDETGRRNYSKYNKFLAMPVLNEYGENEFHYLDCNTSIDGSMEIDDSFHDMSDVMSEHYEMQPLNLQTQYGDEKYDLLDSRGLSFNDMKKPKKTLWKCKKCNYKDPSKEALLEHVREHSKDGIQEEPLKSAGSKKSENTPDPADLAYRCGHCHQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPVSINDINDTCNKCPFRSNDKKLLIAHLQQHQPSPQSVFKCYFCPYFVKDENELSQHLLVHGITEPEDYISKAMEEKSPLQEQQLNPSSCSTKRHRCTECPYETNSKSQYMYHEQFHRTPSDTPYKCPECNYSVSKRHLLHQHLRVHGIITKRLDVEYGLDQPSTSQNKNDGKIDSEGIFYEEIPYVWVSAKNEFHKMYKCRYCSYVNSIQCKIPNHENLHFIVFENNDTTIYKCLECKFTCNNASRLAEHSKSHGEIYGRIYCPVENDSPDEQQIAKLRKVIEMDKGTENFSKEEGVTESREIKMLYFCHMCPARFFEDTELESHKTFHNATLPNKCTSCEYSVSEGNDLAAHETVHTDEYHTKTKILKFLHNLHPTHRQPQLAMAPDSTDSEIKWISIGPPKAENVESNVKKSHDTKHVPKQYFCKLCPAKFFKSSALNYHAALHGGDGDHKCKTCNYAVKNIGNLAKHEILHEKKNKPSNCDYESGEDMDYKNVPLSGTDLFQRKTEAQKRVLIDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGNNGFVMAENQDLNKDESTDNIKLAIKTMPKGPPKSDFQQFSISDQQTLRLLQRRRSINDCAKDLNTNETSPTKERKMHMCLLCPYTNQRQDSLTNHYRRHGDTDALTATNHKCSYCDLVVVQSHFLREHLKTHFNYHKTLTPECFVANEDVGFTITKIEDDSSEPVDLNLNVQNKIFVCKEEKMYVKIATGELLAAWD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00795310;
90% Identity: iTF_00442003; iTF_01361154; iTF_00823498; iTF_01198261; iTF_00157655; iTF_00707452;
80% Identity: -