Basic Information

Insect: Hypercompe scribonia
Gene Symbol: ZNF296
Assembly: GCA_949316085.1
Location: OX438994.1:11832521-11848315[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.21 23 6.7 0.2 3 23 119 139 117 139 0.96

2 14 0.0022 0.23 13.0 3.2 1 23 256 278 256 278 0.99

3 14 1.5e-05 0.0016 19.8 0.8 1 23 284 307 284 307 0.97

4 14 0.002 0.21 13.1 2.5 1 23 312 335 312 335 0.94

5 14 5.7e-05 0.0061 18.0 0.4 2 23 497 518 497 518 0.98

6 14 2.4e-05 0.0026 19.2 1.4 1 23 524 546 524 546 0.98

7 14 2.3 2.5e+02 3.5 0.0 2 23 636 657 635 657 0.95

8 14 0.0014 0.15 13.6 2.0 1 23 663 685 663 685 0.95

9 14 0.00031 0.033 15.7 0.9 1 23 691 713 691 713 0.98

10 14 0.00089 0.095 14.2 2.0 1 23 722 744 722 744 0.98

11 14 0.00063 0.067 14.7 3.0 3 23 792 812 791 812 0.97

12 14 0.015 1.6 10.3 5.3 1 23 829 851 829 851 0.96

13 14 1.6e-06 0.00017 22.9 1.0 1 23 857 879 857 879 0.98

14 14 1.7e-07 1.9e-05 25.9 3.1 1 23 885 908 885 908 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.21	23	6.7	0.2	3	23	119	139	117	139	0.96
2	14	0.0022	0.23	13.0	3.2	1	23	256	278	256	278	0.99
3	14	1.5e-05	0.0016	19.8	0.8	1	23	284	307	284	307	0.97
4	14	0.002	0.21	13.1	2.5	1	23	312	335	312	335	0.94
5	14	5.7e-05	0.0061	18.0	0.4	2	23	497	518	497	518	0.98
6	14	2.4e-05	0.0026	19.2	1.4	1	23	524	546	524	546	0.98
7	14	2.3	2.5e+02	3.5	0.0	2	23	636	657	635	657	0.95
8	14	0.0014	0.15	13.6	2.0	1	23	663	685	663	685	0.95
9	14	0.00031	0.033	15.7	0.9	1	23	691	713	691	713	0.98
10	14	0.00089	0.095	14.2	2.0	1	23	722	744	722	744	0.98
11	14	0.00063	0.067	14.7	3.0	3	23	792	812	791	812	0.97
12	14	0.015	1.6	10.3	5.3	1	23	829	851	829	851	0.96
13	14	1.6e-06	0.00017	22.9	1.0	1	23	857	879	857	879	0.98
14	14	1.7e-07	1.9e-05	25.9	3.1	1	23	885	908	885	908	0.98

Sequence Information

Coding Sequence: ATGAACCACAGCATGGATTTGGACCCACTGAGCACATACGAATACCCAACATACAATAGTTACCATTCGTTAAACAATGCCCAAACGAACCACCTCCCACCGTACCCCTACCAGCATGTCAAACAAGAAGAAACATACTACAATCAACCAATCCAAAACAATACGGGTTATACCACTAGCAAAACACCAGAAACTGTACCTCAGAACGAACAAGTACCACAAGCAAATAAACCGGCACAGCCTAACGAAGAAAGCGAGGTCAAACCAGATGtgactaagaaaaaaaaagataaaaagaacgGAAAAAATTACTGCTCACAAAAGATCAACGATGCATCATATCCTTTCTACGGCTGTTCTGTCTGCAATATCAGTTACACAGCGTTACACGAATTAGACCAACATGTCACTGTACACAAAAATAGAATGACAAGCTACAGGTTAAGACTAAGGAATCAGTATAAGAAGAAACAGataaagaaagagaagaagaaactTAAGAAATTGAAGAAGATAAAACAGGAGACTGAAATGGATATTGAAATTAAACCAGAGGATGGGTACATTGGACATGAAAAAACTACAGACTACGTtaataatgaagaaaataaaatagttacgGATAAAGAAATAGGTGGCAATAATTCTGTTTGTAAAGATTTAGGTAAAGTAGATGATAATAATGGCGCTGTGAGCAGTCAGGAGAGCTGTAAGAGCAATGATAAGGATGCTGACGACACAGAGTTGAATAATTTAgagaaaatttataaatgttttgcgTGTAAGAAGCAGTTTacattaagttattatttaaagttgCACGTGAGATCTCATACAGatgAAAAGCCCTATAAATGCAATATGTGCGGCCAGTCGTTTATAACAGCGAGCAAACTCGGGAGGCACAACAAACGAATACACCTCGCTGCCAGGTTCCAATGtcgaatttgttttaaaatattttctagGTTTGAGTTGCTGACAAATCATTTTGACAAAAGTCATCCAGAAGACAAATTGGAAGGGGAACCCTATGATTACAACGCAATTTTGCCATATCTGAAAGAATTAGAAGAACAACTCAAAGAACAAGCTGAAGCAAAAGAACAGAAGAAAGATGACCCCTGGTTCGAAGTCGCAGTCGCGCCGGATACCGAGGAAGTCAAGAAAGAGGATCAAGATGATGAGAAACTTATACCCAAGATAGACATAATTGTAGAAGAATTGAAAGTGGATAGTTTTGATGAAGTGAAGGTCAAAGAGGAGATAGAAGATGATGAGGGGGAAAATAAACCTGCAGAGGAGATGCCCGGAGACGACTTCAGaaatgatgatgacaatgatgatgttAAACACGAGGACTTTAAGGATGACAGcCTTTCCGATGACGACTACTTCCCCTCCAACACGTGGGCGTCAACACCGAAATGCGATCCATCACCACCTCCGTCACCAAAACCGAGGAAAGCATCGGCATTAAAAACGAACACCTGTGAGATTTGTAACAAGGAGATCAGCTCAGCGTCGTACATGAGGGTGCATATGCGGACCCACACTGGGGAGAAACCCTTCAAGTGTTACACGTGTGGGAGGGGCTTTATAACGAGCAGCAAGATGAATAGGCATGTGCTCACGCATGGAAATGATGCTAAAGAAGAAGAAATCAAACAAGAAGATGATGTGAAAGAAGGAGAGGACGCACTAACAGAAGACGATAGCAGTAGTTCagtaaagagaaaaaagaagaaacggAAGTTAACCAAGACGGTGGCGAAGGGAGAGGAGAAAGTGAGAAAGAAACACCAGAAGAGGCCGCACTCCTGTGAATATTGCAATCAGAAGTTCTTGCACCTGAAGATGCTGGAAGTGCACAAAAAGTGCCACGAGGGCGAGGAGCTGGTGCTAAAGTGCCAGTTCTGCTTGGAAGAAGCCATCGACAACGCCGCCCTCAAGGAACACGAGGCCACGCACTCGGGGCCGAAGCCCTACCTCTGCACCATCTGCGGGAAGACTTACAAGAAGAGAGAAACCATGGTATACCACCGCAAGCAGCACCAGCCCGAGAAGGAGTACGTGTGCGACGTCTGCTCGAAGCGGTTCAGCGCGGCGTGCAAGCTGGCCAAGCACCTCGCCACGCACCGCGAGGGGGGGTTCGTGCTGCGCTACGAGTGCCCCGTGTGCGCGCACATGTTCAACACGCGCTACCACGTGCAGATGCACCTCGCCACGCACCAGAAGGAGGGGCTGATTCTGGAATCGAACCGCAACGAAGTGTTGGCGATGGTGCTGCAGAACGCGCTGAAGATCCCCAAGCAGCCCGACGCGGCCTCAACCCTCACCGACATCACTCCCTCGGACGAGAGGTACAGAATCTGCAAGATTTGCGGCGAAACATTCCACCACTTTTACTACCTCGAGGAGCACCTCAAGAGCCACGGCTCCAAGATCGCCATCGACGACACCAACAAGGCAGAGGAGAAGAAGTACATCTGTGAGATCTGCCACAAAGGCTTCAAGCTGCATTATTACCTGAAGCTGCACAGCTTCACGCACTCCAAGGAGAAGCCCTTCATGTGCCAGCAGTGCGGGAAAGGGTTCATCACTAAGGGCAAGCTCAAGAGACACCTGGAGACGCACTCTGGCCTCAAGAAGTACCAGTGTCACATATGCTACAAGTTCTTCACCAGACCCAGTTATTTGAGGATCCACATCCGAACGATCCACGGAACCCAGGACTACAACTATCGTTTCGACAAGTCGCTCGCGCTATCCGCCATCTCGGCCCTCGCTCACATATCCGATAGACAGAACACGACGTAA
Protein Sequence: MNHSMDLDPLSTYEYPTYNSYHSLNNAQTNHLPPYPYQHVKQEETYYNQPIQNNTGYTTSKTPETVPQNEQVPQANKPAQPNEESEVKPDVTKKKKDKKNGKNYCSQKINDASYPFYGCSVCNISYTALHELDQHVTVHKNRMTSYRLRLRNQYKKKQIKKEKKKLKKLKKIKQETEMDIEIKPEDGYIGHEKTTDYVNNEENKIVTDKEIGGNNSVCKDLGKVDDNNGAVSSQESCKSNDKDADDTELNNLEKIYKCFACKKQFTLSYYLKLHVRSHTDEKPYKCNMCGQSFITASKLGRHNKRIHLAARFQCRICFKIFSRFELLTNHFDKSHPEDKLEGEPYDYNAILPYLKELEEQLKEQAEAKEQKKDDPWFEVAVAPDTEEVKKEDQDDEKLIPKIDIIVEELKVDSFDEVKVKEEIEDDEGENKPAEEMPGDDFRNDDDNDDVKHEDFKDDSLSDDDYFPSNTWASTPKCDPSPPPSPKPRKASALKTNTCEICNKEISSASYMRVHMRTHTGEKPFKCYTCGRGFITSSKMNRHVLTHGNDAKEEEIKQEDDVKEGEDALTEDDSSSSVKRKKKKRKLTKTVAKGEEKVRKKHQKRPHSCEYCNQKFLHLKMLEVHKKCHEGEELVLKCQFCLEEAIDNAALKEHEATHSGPKPYLCTICGKTYKKRETMVYHRKQHQPEKEYVCDVCSKRFSAACKLAKHLATHREGGFVLRYECPVCAHMFNTRYHVQMHLATHQKEGLILESNRNEVLAMVLQNALKIPKQPDAASTLTDITPSDERYRICKICGETFHHFYYLEEHLKSHGSKIAIDDTNKAEEKKYICEICHKGFKLHYYLKLHSFTHSKEKPFMCQQCGKGFITKGKLKRHLETHSGLKKYQCHICYKFFTRPSYLRIHIRTIHGTQDYNYRFDKSLALSAISALAHISDRQNTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00157427;
90% Identity: iTF_00157427; iTF_00441776; iTF_01360917;
80% Identity: -