Hpro025723.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hypena proboscidalis
Gene Symbol
ibtk
Assembly
GCA_905147285.1
Location
LR990144.1:13193409-13207446[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 3.4e-15 1.5e-12 48.7 0.0 9 79 368 437 359 442 0.92
2 4 6 2.8e+03 -0.4 0.1 85 106 507 529 502 533 0.81
3 4 3.3e-13 1.5e-10 42.3 0.0 8 107 557 660 552 663 0.84
4 4 2.5 1.1e+03 0.9 0.2 79 107 664 692 660 695 0.87

Sequence Information

Coding Sequence
ATGAATGTATGCCTCGGCAAGTTCCACAGCGTCTGGCTGTCCGGTTCTGGCGACGTGTGGTGCTGCGGGCAGCTGGCGCGTGCGGGGGGCCCGCATGCCACGGCACTGCGCCCCACGCCATTGAAGCTGCAGGAGCCCTGTGTGGCGATAGCCATCACTATCAACTCTACCATATTTCTCTTGGAGAGTGGAATGGTCCTCCAATACGCTCTAAACAGCACGGACAACATAAGCCAGTCCATTACGAAAGCGCCTTCTTCAATCAAACTATCATCAATAAAGCCGTTGATCAAGTTATCCTCACCGCTGGGCATCCGCTCGGCGCGGTCGCATGCGGTTGTGTGGAACGCCCGCGCCGTATACACGTGGGGAACCAATATTGGACAACTCGGACATTCCAATGAGGACAAAATTGTTGGTGCACCTAAACGGGTAGCAATATCAATGAACAACAAAGAGGAAGCAGTCATCCAGTTGGTAGATGCCACTGACGCAGCAACAGTCTTCACTACGAGCCGAGGAGACGTGTATCTGCTTCACAAGTACATCTGTAAAAAGATTGCTATCAAGCAAATAAATCTGCGTCAAGTGTGCGTAGAAGCGAAAGTGAGTGAGTCGGGCGTGTACTCCCGCGTCACCGTGCTGCTGTTGACCAATGTGGGGCAGCTGTTCATTTGGCAGGACACTACTAACAAACTTACAAGATGCGTATTCGGCCTCGTCCACCAAACCATAATAACGCGCGTAGCGTTAACCCACGACGCGTTGTACTTCACAACGCCATACGGGGAAGCATTCGCCGGCACTATATCCCGCAAAACCACGCCCATTATCTCCCCTCAGCCAATCAAGAAGGAGAAAGAAAGAGGCGACAAGTCCGCCCTCGTCAAGTTTTTAGAAAAGGACGACTGCACTTCTGTCAGGATAGCCAAGATATCGAATGTTTATAGAGCGGTTGATATCGCTGTGGATAGCGAAGGGAATAATTTTGCGTGTTTACAGataaaaccAACTTGCGGGCTAAGATCTATACCGGAGTTATCTCCATCAAGCATGTCTAAACACATGGAGTCTCTAAGGGAAAGTGCATCTGTAGATGATTTACTGCATGATGTGATatttaagGTAGGCCAAAAACAGTACCCAGCGCACATATTCATAATCGCCTCAAGCAGTGAATACCTTTACAACCTATACCAAGACGCTAAAACCAACCCAGGCGATAAACCACAGATAGTACTAGACAACGTGCACCCTGAAGCGTTCGATCGTATCATGAGgtacatGTATACTGGGAGCTGTGACGTCACGGAGTTAGGGCCGTGCGGACTTAAGATTAGGAAGGAGGAATTGGTGGGGAAGACGGAGAAGGATAGTGAAGATGTTGAAGATGAAGTTATTGAAAATCCATCAGAAATCTCAGCTTTCGAAGCATACAACAAGAAGAGTGACAGAGGGAAGCGTCGCAATGGCCGCGGCTCGGAGCCTCCGCGCACGCATCTGTACTGCGACCCCGTCAAGCTCCTGCAAGCCGCGGCCAAGCGACTGCAAGTTATGGCACTGCACAAACTGCTCGATAAATTCTATTACAAAGACGGTAACATCCGCCTAAAGGAAAGCGCCACCTACAGCCGCGACCTAACATCACCATGGCAACGGGAAACCCTCACCGAATTAGTGGATACCAGCGTTGTGTCCAAGGACAATGTGCCGATTCCTGCACATAAGTGTGTGCTGGCTGCCAGGCTGGAGTACTTCCAGGGGATGTTCATGCATTCTTGGACTGAGAACAAACTTCTATCAAAAGTCACACTGCCAATCAACTACAGCATTCTACTGCCAGTTATCGACTTTCTCTACACAGACCAGTGCCCAGAAATAGAAAACTCCGACAGCATCGACTTTATTTGCAACCTAATGATCGTAGCGGACCAACTCTTTATCGGCCGTCTAAGAGAAATGTGCGAAATGGCACTAGCTAACTTGATATCTCTGAAAAACTGCACAGAACTATGTCAATTCGCACACACGTACAACGCTACACAGCTAAAACAATGCTGCATGGAGTTTATATCACTCAACCTGTGCAGTGTCCTCGAAAATAGAGCGTTAGACCTACTAGAAGAAGAATTACTTGATGATATAACCAAGTATTATTGCAAGTTCAACCCCATAATGTCATCTAGGGTTATCACTCCATTCTTTAATGCACCAAGTGATGAAATCATTGAAGAATTTGCCAAAAACTATCCTGTCAATATGGATATAACCAACGAAGAGTATATGAGAGATGATAGTATGGTAGAAATATCTAAGAAGAGAAATAAACCGAAGAAAATTGATTATACAGATAGTGAGAAGGAACGCATGAGGTACGAATCTGTGAGTTCGGTGACTTCCCTAGATCTATCTAATGAAGTTTCTGGTGATATAACATTATCTCTAAGCAAGATATCTAAAGATACTGAGAAAGGAACCCGGGAGAAACAAGAGAAGTGGATTGAAGTGCCATCATCGCAACAGAAGCAACAGAAAGTGGTCCAAGCGAGACTGAAAGCCATAAGTAATGCTAAAGATATACTGAATGAACCTCCCACCGAATCGTTTGTAAAACTTACCAAGAGTAGTTCGTCCAGTGCCATGGTAATACAAGAGAGTTTGACAAAATCTTCACGCATGTCAGTATCACCAAAAGATTCTCCCATAGCCGAAATGGCCAGAAGTCCACAGGGTAATTTTGTCATAAGCCATGTGGGACCAAAGTTATCTCAGAAACAAAGGAAGAAGTTGGCTTTGCAAGGGAGTGATTCTTCTCAAAGTCTagaagattattttaataagactAATATTGGTAGTCCATCTGAAAAACCAAAGAATCCTTGGAAGATTTGTGAAGCCGCTGTGGCTAGTAGCAGCCCTAATTCGAAAGGCATAGAgttcaataaaattttgactGACCAGAAGAAGCAAAAAGAAGATTCGTCAAGAATCATGGGCAAACCACTTGCTATGACTCagCTGGAAGATAGAGCAATAGAACAGCTAGAAAGATTCTACAACATTCATGAGATTGATGATGAATTGATCACAGTGAGACGCATCGAGCTTCAGGTGTATTCACCGCAATGGATCCATACTGCCCCAAAGTGA
Protein Sequence
MNVCLGKFHSVWLSGSGDVWCCGQLARAGGPHATALRPTPLKLQEPCVAIAITINSTIFLLESGMVLQYALNSTDNISQSITKAPSSIKLSSIKPLIKLSSPLGIRSARSHAVVWNARAVYTWGTNIGQLGHSNEDKIVGAPKRVAISMNNKEEAVIQLVDATDAATVFTTSRGDVYLLHKYICKKIAIKQINLRQVCVEAKVSESGVYSRVTVLLLTNVGQLFIWQDTTNKLTRCVFGLVHQTIITRVALTHDALYFTTPYGEAFAGTISRKTTPIISPQPIKKEKERGDKSALVKFLEKDDCTSVRIAKISNVYRAVDIAVDSEGNNFACLQIKPTCGLRSIPELSPSSMSKHMESLRESASVDDLLHDVIFKVGQKQYPAHIFIIASSSEYLYNLYQDAKTNPGDKPQIVLDNVHPEAFDRIMRYMYTGSCDVTELGPCGLKIRKEELVGKTEKDSEDVEDEVIENPSEISAFEAYNKKSDRGKRRNGRGSEPPRTHLYCDPVKLLQAAAKRLQVMALHKLLDKFYYKDGNIRLKESATYSRDLTSPWQRETLTELVDTSVVSKDNVPIPAHKCVLAARLEYFQGMFMHSWTENKLLSKVTLPINYSILLPVIDFLYTDQCPEIENSDSIDFICNLMIVADQLFIGRLREMCEMALANLISLKNCTELCQFAHTYNATQLKQCCMEFISLNLCSVLENRALDLLEEELLDDITKYYCKFNPIMSSRVITPFFNAPSDEIIEEFAKNYPVNMDITNEEYMRDDSMVEISKKRNKPKKIDYTDSEKERMRYESVSSVTSLDLSNEVSGDITLSLSKISKDTEKGTREKQEKWIEVPSSQQKQQKVVQARLKAISNAKDILNEPPTESFVKLTKSSSSSAMVIQESLTKSSRMSVSPKDSPIAEMARSPQGNFVISHVGPKLSQKQRKKLALQGSDSSQSLEDYFNKTNIGSPSEKPKNPWKICEAAVASSSPNSKGIEFNKILTDQKKQKEDSSRIMGKPLAMTQLEDRAIEQLERFYNIHEIDDELITVRRIELQVYSPQWIHTAPK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00869791;
90% Identity
-
80% Identity
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