Basic Information

Transcription Factor Domain

TF Family: CBF
Domain: CBF_beta domain
PFAM: PF02312
TF Group: Beta-Scaffold Factors
Description: Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.9e-14 1.2e-09 40.8 0.1 1 28 30 57 30 63 0.96

2 2 1.1e-31 6.6e-27 96.9 0.0 12 100 99 186 92 191 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.9e-14	1.2e-09	40.8	0.1	1	28	30	57	30	63	0.96
2	2	1.1e-31	6.6e-27	96.9	0.0	12	100	99	186	92	191	0.88

Coding Sequence: ATGCACGACCCGACCGGTCTGGCGGGCATGCTGCCCTTCGAATCCATCGGCCTCTACGAGCAACCCAAACCCCGGTTCATCTTCAAGATGCCCCGGGTCGTCCCGGACCAGAAGTCCAAGTTCGAGTCCGACGAGCTCTTCCGGAGACTCAGTCGCGAGAGCGAGAGGCGCGGTCCTGTCGTCGGGTTCCCGGAAGGCTCACTCGGACTTCCCGTTCACTTCGCATTCCCGACCCGCGAGTCAGATCCTGAGCTACTTAATTCGCGACAGTGCAGCCAACCTTGGCGACAACGCCAATCATCTAACAAATCAGTTACGCGAATAAACGCCAGCATGACGGTGAGGTACACGGGGTACCGTGATCGACCTCAGGAAGAGCGCCAAGCTCGCTTCCAGAACGGCTGTCGAGAAGGGCATACGGAAATTGCCTTTGTGGCGACAGGCACAAACATACAGCTGATATTCAGCCCTAGTACAAACGGATACAGTACGTCGGACCACGGCCGAGAATGCGAGTTGGACAAGGAACCCGGCAAAGTGAGCCTGCGGGCCCCTGTGTGGGAACCTGGCGAACTGCGTGGGGTCCGCACTCCAGCTGTTGTTGTCGCGTGCTTGCGTGACGTAGAAACGTCTTTACCGAGCCGATTGCTGCAACTAAACGGACAATTTCCTCTCCGACTGTCTGTTCTTCTGGAACAAGCTCTTTCTTTCTCTTGGCGGGCCCTTTTGCTGCCCAGGTATAGTCCGCTACCCTCGCAAACTGGATGA
Protein Sequence: MHDPTGLAGMLPFESIGLYEQPKPRFIFKMPRVVPDQKSKFESDELFRRLSRESERRGPVVGFPEGSLGLPVHFAFPTRESDPELLNSRQCSQPWRQRQSSNKSVTRINASMTVRYTGYRDRPQEERQARFQNGCREGHTEIAFVATGTNIQLIFSPSTNGYSTSDHGRECELDKEPGKVSLRAPVWEPGELRGVRTPAVVVACLRDVETSLPSRLLQLNGQFPLRLSVLLEQALSFSWRALLLPRYSPLPSQTG

Sequence clustering based on sequence similarity using MMseqs2