Hves010259.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hyles vespertilio
Gene Symbol
egg
Assembly
None
Location
HLhylVes1:4996650-5028798[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 3e-14 1.4e-10 41.0 0.0 5 75 1461 1524 1458 1526 0.91
2 10 0.11 5.1e+02 0.8 0.0 49 75 1539 1563 1536 1565 0.87
3 10 0.11 5.1e+02 0.8 0.0 49 75 1578 1602 1575 1604 0.87
4 10 0.11 5.1e+02 0.8 0.0 49 75 1617 1641 1614 1643 0.87
5 10 0.11 5.1e+02 0.8 0.0 49 75 1656 1680 1653 1682 0.87
6 10 0.11 5.1e+02 0.8 0.0 49 75 1695 1719 1692 1721 0.87
7 10 0.11 5.1e+02 0.8 0.0 49 75 1734 1758 1731 1760 0.87
8 10 0.11 5.1e+02 0.8 0.0 49 75 1773 1797 1770 1799 0.87
9 10 0.11 5.1e+02 0.8 0.0 49 75 1812 1836 1809 1838 0.87
10 10 0.11 5.1e+02 0.8 0.0 49 75 1851 1875 1848 1877 0.87

Sequence Information

Coding Sequence
ATGGCGGACTCGAAACCTAAAGTCGGATTGGAGATATTCAACTTGGATTCTGATGATGAGGACATCGGCAGCTCTAATAAAGAGTTCATCTCGggccccgctgtcggcgctggagctggacgcggcgctgcgcgcgggacgctgcgtgcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACATAGTGTTCACTGcggcgcggctgcggcgccggcgcccgcccgCTCGCACTCTACTGCCACCACTGCGCCGCGCTGCACCTGCGACGCACGCAGGTACTGCACTGCACCTCACACACAGGGAGTTGGTGGAAGGCATCAAGAACATGACTCCGTTGctggaactgaacatggacaggctggaccaggacctggTGGAGATATCCGACTCGGAGTCAGAAGACGAGCCAAATGAGCCCAAGGATAGGATCGGCGAGGAAGGTGCCAAGATACTTGAAGAGAACTTGGCCGACATAATAAACAGCATGTGGCGCAAATACAAGATGGACGCCAGCCTAATAGACGCTAAAACGTTACTCGACGCCGAGACGGAACGATTGGAGAACGAGAGCAAAGAGATAAACAAGTTGTTGAACGAGTGCCAAGCCGCCACGGACAAGCTGCGCGGTGAACTGTACGCCACGTTCGAGCCGCGTCGCCACCACAGGCCCGCCATACACATCTACGATACTGCCGAGATTATGACAGTGGAGGATGAAAATATGTCGGGCGATCAGAATTCCGTGCCTGAGACGAGGCAGGCGAAACGTCGGCTGTCTGGTCCAAACATACAGCCCGCCAAGAGACCTGCCATACCTCTTGGCTATGCGCCGCTGGACAACGATGCCAACCAGAATGCACAACAGGAATACACAGCTGTTCTGAGAGTTGGAGAAAGCAGCAGGTTGGATGATGATTCGGAGGTGTCGGTGGTGCAGCTGTCGTGTGAGGCGGCGCCGCGCGACCTGCCCGCGCCGGGCGAGGTGTCGCGACCTCCGCTGCGCGCCGCCATGCAGGTGTACGCGATGTCCAACAACGGACACTGGTACAAGGCGAGGGTTGTGGACCAGGTTCGATTCTTAGGGTCCCAGCCGCAGTTTCCTTCGTACCGCGTGCGTTTTGAGAAGCGCGTGAAGAATCCCTGCAGGGTGGTGTCGGCTCGATACCTCGCGTACAGCGAACCGGCTGATGTCAGGCTCACGATAGGTACTAGGGTCATAGCGTTGTTCAAAGAAACGGTGAACACGAATAAGAAGAATACTTATTCATCCGGTATCATAGCTGAGATACCCAATCCAGTTAACAGCTATAGGTATTTGATATTCTTCGACGACGGTTACGCTCAGTACGCGTCTCACGCGCACACGCGCGTTGTGTGCGCGTCCGCCACGCCCGTGTGGGAGGAGGTGCACCCGTTTTCGCGCGAGTTCGTGCGCACTTACCTCTGTGCCTACCCCGAGAGGCCCATGGTGCGGCTGCACGCCGGACAGACGCTCAACACCGAGTGGAACGGCAAATGGTGGGAGTCCCGTGTGATCCAAGTAGATGCGTCCCTCGTGCAAGTGTACTTCGAGGAGGACAAGCGCACGGAGTGGATCTACCGCGGGTCCACCCGGCTGGAGCCGCTGTTCCTGGAGCTGCAGGCCGCCGTGAAGCCCAGGGGACGACACGTGCCAAGGACCAAGGCGATGGGGAGTATCAACAAGCCATACGTGGAGTATACAAGATCATACGAGCAGGAAAAATCTATTGACGCGCAGCAAGAGGAGTTGCGCCGACAACGAGCGGTGGCTAAGAAGTCCACGACAACCGCCACACCAGGCGTTCAGGAACAACAAGATCCCTTCGCTAGCAGAGTTGTCTACTACACTCCGCGCAACGCGGTGCGTCCGTACAAGATGACGACACACATCTGCGGGCCAAAGTGCAAGCGCACTGACGTGTTGACTCTGAAGGAGTTGCGCTCGTACAATCCCCTGGCGAAACCACTGCTAAGCGGGTGGGAGAGACAACTGGTCCGCAACAAGGGCGTGTCGTGCGTGCTGTACCGCGCGCCGTGCGGGCGCCGCCTGCGCCACGCGCGCGAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGCTGCACCGCTACCTGCGCGCCACCCGCAGCGACCTGCCCGTCGACCTGTTCGACTTCAACCCCGACACGCACTGCCTGGCCGAGTTCGTGCTCGCCAAGTGCATCGTGGGGAAGAAGGACCTGTCTCACGGCAAGGAGAACGTGCCGGTGCCCTGTGTGAACAGCGTGGACGCGACACTCCCGGAGTTCTGCTCGTACAACACGGAGCGCACGCCCACGGCCGGCGTGCCGCTCAACCTCGACCCGGACTTCCTGTGCGGATGCGACTGCACCGACGACTGCGAGGATAAGACAAAGTGCGCATGTTGGAAGCTGACACTAGAGGGCGCCAAGACCATCGGCATGGAGGGCCCCAACATCGGCTACGACTACAAGAGACTGCCCGAGCCGCTGCCTTCCGGCATCTACGAGTGTAATGTCAGGTGTAAGTGTAAGCACACATGCCTGAACCGGGTCGCGCAACATCCGTTACAGCTCAAGTTGCAGGTGTTCAAGACTCCGAACCGCGGCTGGGGCATCCGCGCGCTCAACGACGTGCCCAAGGGCGCGTTCCTGTGCGTGTACGCGGGGAACCTGCTCACCGACGCCACCGCCAACCTCGACGGTTTGAACGAAGGCGACGAGTACCTCGCGGAATTGGACTACATCGAGGTGGTGGAGCAGATGAAGGAGGGATACGAGGAGGACGTGCCAGACGCTGACAAAATACTAGACCAGAAGGAGACAGAAGTGAAAGAAGAGAAATCGGAGGAGGAGGAATCCTCTTCTTCGGAAGAAGAGGAAGTAGTCTCCAAGAACGAGGAGCAAGACGACGACTTCAGACCAGGGTATATAGGATTAGGAGTTATGGAGTTCAAgaacagtagcaaaaccaaacaccttgaattgcaaagcaatgcttggcattccactccgctcgccatcctgagacataagatgttaagtcccaatttgtccaTAAGAGACTTCGTAAACGCGGAAaaagtaagaaagaagaaaaagaagaaccgaaagaagagcaggaacagaaaggcaaggagtcgaacgcagaagatgaCTGCATCACTATCAGCGACGACGAGGAAGTACGCGAACCGTCCAGATTCACCGCACAAACTGAAATGGGCGCCAACGAACACGTGCCTAAATACAGATCGGTTCGTTCGTATTTCGGCAAGGACGAGGCGTGCTACATCATGGATGCTAAGGTTCAAGGGCAACATTGGACGATATCTTAATCACTCGTGTTCCCCGAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTGGCGTTCTTCGCGCTGAGCCACATCCGCGCCGGCACCGAGCTCACCTGGAACTACAACTACGACGTGGGCTCCGTGCCCGGCAAGGTGCTCTACTGCTACTGCGGCGCGCCCAACTGCAGGAGGCGGCTGTTGTAA
Protein Sequence
MADSKPKVGLEIFNLDSDDEDIGSSNKEFISGPAVGAGAGRGAARGTLRAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHIVFTAARLRRRRPPARTLLPPLRRAAPATHAGTALHLTHRELVEGIKNMTPLLELNMDRLDQDLVEISDSESEDEPNEPKDRIGEEGAKILEENLADIINSMWRKYKMDASLIDAKTLLDAETERLENESKEINKLLNECQAATDKLRGELYATFEPRRHHRPAIHIYDTAEIMTVEDENMSGDQNSVPETRQAKRRLSGPNIQPAKRPAIPLGYAPLDNDANQNAQQEYTAVLRVGESSRLDDDSEVSVVQLSCEAAPRDLPAPGEVSRPPLRAAMQVYAMSNNGHWYKARVVDQVRFLGSQPQFPSYRVRFEKRVKNPCRVVSARYLAYSEPADVRLTIGTRVIALFKETVNTNKKNTYSSGIIAEIPNPVNSYRYLIFFDDGYAQYASHAHTRVVCASATPVWEEVHPFSREFVRTYLCAYPERPMVRLHAGQTLNTEWNGKWWESRVIQVDASLVQVYFEEDKRTEWIYRGSTRLEPLFLELQAAVKPRGRHVPRTKAMGSINKPYVEYTRSYEQEKSIDAQQEELRRQRAVAKKSTTTATPGVQEQQDPFASRVVYYTPRNAVRPYKMTTHICGPKCKRTDVLTLKELRSYNPLAKPLLSGWERQLVRNKGVSCVLYRAPCGRRLRHARELHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKLHRYLRATRSDLPVDLFDFNPDTHCLAEFVLAKCIVGKKDLSHGKENVPVPCVNSVDATLPEFCSYNTERTPTAGVPLNLDPDFLCGCDCTDDCEDKTKCACWKLTLEGAKTIGMEGPNIGYDYKRLPEPLPSGIYECNVRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDVPDADKILDQKETEVKEEKSEEEESSSSEEEEVVSKNEEQDDDFRPGYIGLGVMEFKNSSKTKHLELQSNAWHSTPLAILRHKMLSPNLSIRDFVNAEKVRKKKKKNRKKSRNRKARSRTQKMTASLSATTRKYANRPDSPHKLKWAPTNTCLNTDRFVRISARTRRATSWMLRFKGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALSHIRAGTELTWNYNYDVGSVPGKVLYCYCGAPNCRRRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-