Basic Information

Insect: Hyles lineata
Gene Symbol: Zeb1
Assembly: GCA_030180105.1
Location: JARJEE010000036.1:3002344-3013104[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0012 0.085 13.9 2.7 1 23 212 234 212 234 0.98

2 11 0.32 23 6.2 0.3 1 23 241 264 241 264 0.90

3 11 0.0003 0.022 15.8 0.6 1 23 295 318 295 318 0.97

4 11 0.12 8.9 7.6 0.4 1 23 322 345 322 345 0.89

5 11 0.23 16 6.7 0.2 1 17 353 369 353 372 0.90

6 11 2.2 1.6e+02 3.6 0.4 2 23 387 409 386 409 0.90

7 11 0.0024 0.17 12.9 1.5 2 23 415 437 414 437 0.96

8 11 0.00011 0.0079 17.2 1.0 2 23 455 476 454 476 0.97

9 11 8.2e-06 0.00059 20.7 2.2 1 23 482 504 482 504 0.99

10 11 1.7e-05 0.0012 19.7 3.5 1 23 510 532 510 532 0.94

11 11 2.3e-06 0.00016 22.5 2.2 1 23 538 561 538 561 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0012	0.085	13.9	2.7	1	23	212	234	212	234	0.98
2	11	0.32	23	6.2	0.3	1	23	241	264	241	264	0.90
3	11	0.0003	0.022	15.8	0.6	1	23	295	318	295	318	0.97
4	11	0.12	8.9	7.6	0.4	1	23	322	345	322	345	0.89
5	11	0.23	16	6.7	0.2	1	17	353	369	353	372	0.90
6	11	2.2	1.6e+02	3.6	0.4	2	23	387	409	386	409	0.90
7	11	0.0024	0.17	12.9	1.5	2	23	415	437	414	437	0.96
8	11	0.00011	0.0079	17.2	1.0	2	23	455	476	454	476	0.97
9	11	8.2e-06	0.00059	20.7	2.2	1	23	482	504	482	504	0.99
10	11	1.7e-05	0.0012	19.7	3.5	1	23	510	532	510	532	0.94
11	11	2.3e-06	0.00016	22.5	2.2	1	23	538	561	538	561	0.98

Sequence Information

Coding Sequence: ATGGAGGAGGTGTTAGCATGTCGTGCGTGCCTCGCTACGGGCGTAAAATTGCATAACATGCACTCAAATAATCTTGTTAGCGCCTACGAAAATCTTACTGGATTTAAGatgATAAAATCAGAGAACTTTCCGGAACACATGTGCACATACTGCACCACAATGCTACTGAAGAGTGTATCATTCAAAGACAAGTGTAAAAGAGCCATGGATGTGCTGAACTCAACTCTTATTCAATCTGGAATGGTAACTCCGATTGATATTCTGAACGTGGATAGGCAGTACAACAATTTAGCGCTCCCTTACAAGTGTCAAAGTCAAGTAATATTGATAAAAGAGGAGACTGGGAATGAGCAAGAAGAAGCTATTGAGGAAATGGATAATGACTGCTTCGgcgatgataatgatgatgcaGatACATCAAACACACCAGAAATGAAAGATATAAAAGATATAGAAAGCAGTGAAGACGAACCTCTATCTTTAAAAGTGGAAAAGAAAAAATCCTCAAAAGATATCTTGCCGAAGAACAAAGATTTTCAGAATGTCAACATAGAACTTATTACATTGACTAAAGAAGAACAAATTCAGGAGGTATTGGCGAGAAAATTGTCTGTGAATTATCAGAATTCTCTGTATAAATGTGATAAGTGTTTCAAAGGGTTTATAACGGATGTGACGTACAAGAATCATATGTATAGACATGATCCGTCTGCGGGTCCCCATTCGTGCGAAGTCTGCCACACTCGCTGGGTGAGTGCTCGCGCGTTGCGCTCACACATTGTAGCGGCGCATGCGCGCAAGTTCGTGTGTCGCGCTTGCGAACACGTCACACGCTCCGTGCACAGAGCCAGGGAGCACGCTTACTGGCACAACGGCCACACGTTTCGTTGCAAAGTGTGCGGCGCTATATTCGCCAAGTCGACGAGTTATCTCACGCACCTAAGGTTGCAACATCCATCCAAACACCGCTGCGAACTCTGCGGCGAATCCTTTCTGGGTGTCAACGGGTTGAATATACACAAGAAGAAAGCGCATCGAGTTAATCAGATGGAAGAGTTCGTCTGCAGCGAATGTAAAGCGGTGTTTCATAATCGTGAGGCGCTTGAGTTCCACGAGTCACTGAGACCTGATAACTTGGGCTGTGGTACCGGACTCAAacCGTGTGCTCAATGTGGGCACAGCTATCTCACAGAAGAAAGATTACAAGAACACGTGACTGTACAACATAGAGTCGACTCCCTCAAATGTTTACAGTGTGACCGTACGTTTGCGCACAAGCGTTCTATCGCGGTGCACTACCAACGCGTGCACCTCGGCCTCAAAGTGAACTCCGGCAAGGACGGCCGGAAGAAACTAGTCGTCGTCTGCGAGATATGCGGACTCAAGTGTATCTCGAAAGCATCGCTAGTTCATCATCAAAGGATTCACTCCGGAGAGAAACCGTTCCAGTGTCCAGAGTGTCCTAAGAAGTTTAGCGTGTGTCAGAGATTGCAgATCCATCTACGAACGCACACAGGGGAGAGACCGTTCAAATGTCACATGTGTCCGAAGGCTTTCAAGCACAAAGCAGCCCTCAACAGACATGACAGGGTGCACACAGGCGCTAAGCCGTACTCGTGCGTGCACTGCGGCAAGTCGTTCTCGCAGTCCAACTCCATGAAGCTGCACGTGCGCACCGTGCACCTGCACCTGCCCGCGCCCTACAGGACCGCGCGCCACGCCGCGCACACATGA
Protein Sequence: MEEVLACRACLATGVKLHNMHSNNLVSAYENLTGFKMIKSENFPEHMCTYCTTMLLKSVSFKDKCKRAMDVLNSTLIQSGMVTPIDILNVDRQYNNLALPYKCQSQVILIKEETGNEQEEAIEEMDNDCFGDDNDDADTSNTPEMKDIKDIESSEDEPLSLKVEKKKSSKDILPKNKDFQNVNIELITLTKEEQIQEVLARKLSVNYQNSLYKCDKCFKGFITDVTYKNHMYRHDPSAGPHSCEVCHTRWVSARALRSHIVAAHARKFVCRACEHVTRSVHRAREHAYWHNGHTFRCKVCGAIFAKSTSYLTHLRLQHPSKHRCELCGESFLGVNGLNIHKKKAHRVNQMEEFVCSECKAVFHNREALEFHESLRPDNLGCGTGLKPCAQCGHSYLTEERLQEHVTVQHRVDSLKCLQCDRTFAHKRSIAVHYQRVHLGLKVNSGKDGRKKLVVVCEICGLKCISKASLVHHQRIHSGEKPFQCPECPKKFSVCQRLQIHLRTHTGERPFKCHMCPKAFKHKAALNRHDRVHTGAKPYSCVHCGKSFSQSNSMKLHVRTVHLHLPAPYRTARHAAHT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00429324;
90% Identity: iTF_01430210;
80% Identity: -