Basic Information

Insect: Hyles lineata
Gene Symbol: Hr39
Assembly: GCA_030180105.1
Location: JARJEE010000028.1:3639228-3656526[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.5 2.3e+04 -5.0 7.9 63 163 208 308 159 334 0.47

2 3 9.5e-08 0.00085 19.4 0.1 1 20 439 458 439 464 0.91

3 3 2.9e-65 2.7e-61 208.8 0.0 165 408 502 757 470 757 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.5	2.3e+04	-5.0	7.9	63	163	208	308	159	334	0.47
2	3	9.5e-08	0.00085	19.4	0.1	1	20	439	458	439	464	0.91
3	3	2.9e-65	2.7e-61	208.8	0.0	165	408	502	757	470	757	0.84

Sequence Information

Coding Sequence: ATGAGCAGTGAGGGAAACGCTGTGAAGGTGGAAGGGGGACACGTTTCTGTCACCACGATCAGCATGTCGGGCTCAGAGACCAGTAATGGCCAGTTCTCGTATAGTTCGAGCGGAGTTCGCATCAGTGTCTCTTCGGAGCCGCATGACGAAGACTCCACTGATGCGGAGATCTCCAAGATCGACTTCACACAGCACCAATACGAGGTAAACATGAGGAACAAGAAGAAACGGTCGTCCAGCGGCGCGCATTGCGACCTGCAGAACAACGACCGGGAGCGGCCCATGTCGTGGGAGGGAGAGCTCTCCGACTCTGAGATGGTCATCGATACTAGTGTTAACAACGACGAGAACAGCAGTTCACTGGACCTGCAGTCGTCCCGCGACTCGATCGACACGCTGCGCAACGTGAGCATAAAGACGGAGCCGCTGAAGGGCGAGCCGTTCCCTTCGCTCGACGAGCAGCGCGTGCTCGACCTCAAGTACGCGCCGCTGCAGCCGCACCAGCGCAGCCTCAGCATGAACAGGATATCAGTGCTAACAGACACGAGTTCCCTCTCGTTGGCGCGGAGGCCATCGTCGCCCACCAACAGTGCCAAGTCACTTGCACTGTCGGACCAGGGTTCAGTGCCCGTTATGCAGCAGACCAATGTAGGCGAGGTGCAGAACCTCACCATCAAGAAGGAGACGCAGCTATCAGaGTTGAAGTGCGAACCATCAGCGGGCATGGACAAGTTGATTGGAGCCCTACACGGGTCGCCACTGCTAGGTAGATTGCCGCGCGTGCAGTCCAGCGCGAGCACTGACTCCGCCGTGCACTCCATGTATACGCACagcGTGTACAGCAGTCCGTCGGCGAGTCCGCGTGCGTCGCGTCACTACACGCCGTCCCTCTCGCGCAACAACAGCGACGCCTCGCACTCCTCCTGCTACTCCTACTCCTCGGAGTTCTCGCCCACACAGTCGCCAGTGCAGGGCCGGCATCCGCACGTGGTGTACCGGGAGCCGGGCGGGGTGCTGTCCCCCGCGCATGATGACGACGCCGAACCCACTGACGAGCGACTGCACCACCACCAGGGCATCAGCAGGCAACAACTCATCAACAGTCCATGTCCGATCTGCGGCGACAAGATCAGCGGGTTCCACTACGGCATCTTCTCGTGCGAGTCGTGCAAGGGTTTCTTCAAGCGCACAGTACAGAACCGCAAGAACTACATGTGTCTCCGCGGCGGGAACTGCCCAGTCACCGTCGCCACGCGCAAGAAGTGCCCAGCTTGTAGATTCGACAAGTGTCTAGGATGCGGCATGAAGCTTGAAGCGATCCGCGAGGACCGCACGCGCGGCGGTCGCTCGACGTACCAGTGCTCGTACAGCCTGTCGGGCGCCGCGTCCACCGGCTCGCTGCTGTCCGCGCACGCGCCCACCACGCTGCGGCACGCCTCCAGCCTCACATGCgtAAACGGCCCAGGATCATACAACAGTCGAGGAGAGCCTAGCAACAGTAGATTAACGCCGGACATACCGCCTTTATTACAAGAGATAATGGACGTGGAGCACCTGTGGCAGTACAACGAGTCTGAGCTGAACCGGCTGGGCAAGTCCCCGGGCAGCCCGTCCGCCAACCCGCTGCTCGCGGCCAGCGGCATCACCGCGCAGAACTCCAGCCCGGACTTCCTAGCGGACCTGTGCAACATCGCGGATCATCGGCTTTATAAAATCGTCAAGTGGTGCAAGAGCTTGCCGCTTTTCAAGAATATTTCCATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGTGAGTTGCTGGTGCTGTCGTGTTGTTACCGGGGGGTGAGCACGCCCGGGGAGGTGAGGGTGGGCGGCGGCCGGGGCATCACACTACATCAAAGTGCCAAATTGGGATTGACGCCGTGTATAGAGCGTATGTTGAGCTTCACCGACCATTTGAGAAGACTGCGAGTGGACCGCTACGAGTACGTCGCGCTGAAAGTCATCGTACTGCTCACTTCAGACGCGCCGGAGCTGCGCGAGGCGGAGAAGGTGCGCGCGTCGCAGGAGAAGGCGCTGGCGGCGCTGCAGGCCTACACGGCGGCGCACTCGCCCGCCACGCCCGCCAAGTTCGGCGAGCTGCTGCTGCGCATCCCCGAGCTGCAGCGCACCTGCCAGtttttcatGCAAGTAGGCAAGGAAATGCTGAACCCTGCGAACAAGAGCAAGGATGGAGACGGACCAAGCTTCAACCTCCTCATGGAACTACTGAGAGGCGACCACTAG
Protein Sequence: MSSEGNAVKVEGGHVSVTTISMSGSETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGAHCDLQNNDRERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSRDSIDTLRNVSIKTEPLKGEPFPSLDEQRVLDLKYAPLQPHQRSLSMNRISVLTDTSSLSLARRPSSPTNSAKSLALSDQGSVPVMQQTNVGEVQNLTIKKETQLSELKCEPSAGMDKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTQSPVQGRHPHVVYREPGGVLSPAHDDDAEPTDERLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYNSRGEPSNSRLTPDIPPLLQEIMDVEHLWQYNESELNRLGKSPGSPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPATPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00033911;
90% Identity: iTF_00806824;
80% Identity: iTF_00819275;