Basic Information

Insect: Hydrotaea cyrtoneurina
Gene Symbol: -
Assembly: GCA_958296145.1
Location: OY282513.1:97819549-97823481[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.7e-12 1.6e-08 34.5 0.0 8 69 291 348 286 353 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.7e-12	1.6e-08	34.5	0.0	8	69	291	348	286	353	0.85

Sequence Information

Coding Sequence: ATGGAAGTCGACGATGCGATAGTCGTCATGACTGAACCAACAGcgtcatcagcagcaacaacagccgaCAACGACAAGACTGTACTTGGCGGCACTGAGGGCGGCGAACCAGCAGATCAGACTACGCCAAGCAGTTCGTCGGCCAAACAGAAGCGTGCCAAACTCAAGCATGACAAAGAAGAGCCCCCAGGAGGGGATGTGGACATACATAACAATGATTCGGTGCTGACGGCAACTCCCTTCAAGTTGGAAGTTTCGGGTTCGGAAGATGAGAGAGATAATGACGGTGATGCTGATGATAACAACGGTGCAGATGGTGTAACAAGGACTGCCATACGGCGTAAACTGTTGTCCACACCGCTGGAAGACGATGGGTCAGCCAACGATGGATTGGAGGAGCTGCAAGAAGTGTCCGTCAAGAGGAAACGTTATGAGGTGCGACGGTCGGGCTCGGAAGAATGTCTTTTGGGCTTTGACGAGTTGAGTGGCGAGGCACAACTGATTAAAGCTGAGGTGGAGGAAAAAGCGCCAGCAGCAAAGGAAAATCTCATTGTAGACACAACACCGGCCGTAGTTCACGAAGTCGCCATGAATTCTCCCAAATCTGTAAAAAAGACACCCCCTCAAAAAGTTGCTCAATCCCCCTCGCAAAACAATACACGCTCTTCTTCAAGGTCTCCCATGGGTGCGAAACCAAAATCTCCTCAACAGGAGTCTCCTCCACAGAATAAATCTGTACAGAAAACTCCACCCAAGCCTCACATTGTGGCCGATGGAGAGGAGACTAATGGCACTGCCGATGTGAAGCCTGCTGTACAGACTCCTCCTTCTGCTGGTAAAAAACCTCTTTCTCCAAAAGACGATTACTATAGGAAACCTTTCGATTACGGCTGGAAGAGAGAGTTGGTATGGCGGGCGAATTTGGAAACTAGCAAGGACAAAGCCGATGTCTATTTTATATCGCCGGCCGGCAAAAAGCTGAGAGCCCGTAATGAAATTATCCCGTTGTTGGAGGGAGATCTGACCATAGATCACTTCTGCTTTATACGTGAGCCATTGGGAGCTAGTGCCGATTTGGAAACAGTCCGTAGCGCTAAGCCTTCATCGCGAGCTTCTGTGACCACGGCCACACTGGCAGCTGCCCCATCGCCACCCATTGTAGGTAAGCGCGTGTCCAAACCGAAGGGTCCCAAGGGAGCAAGTCCACCTCCGCAAGGCTGGACTCCCAGCAAAGCCTTGAAGGTCAACAATGCTGCTTTACTTAGTTCTGGCGGCGGTGGTGGAAGACTCTCACTGTCTGCCCAGCACCATCATCAACCGCAACAGCCTTTGGGCACCGCTCTCGGCAGCCGTAGGCTTGAAAATAGCGGCCAAAATATCAGCCATTCCGCGAAGagcagtaaaacaaaaaaATTATCAGCCCAGTCGTCAGGTGCCAAAGCCGATGGACATCCCAGCTATGATGTTCGCAGGGCAGCGGTAAGATCAGAATTGAAAGAATCTTGCAATATTGGTTGTGTCAAGGCGACGGGTCAGTTGCCCCAACTGCAATGTACGAAATGCTTTTGTCTCTATCACCACGAATGTGTGGGAATTGATCGGAACACCAGTGACTTTCGAACAACGTCCAGCACCCATGGCCGCGAGTACATATGTGAGGGTTGTGTTCCGAAACCGTTGCCAAAGAACAGCAATCAAAGTTCACAGCTCACGCCTGTTAATGCACCCATGCCAGCACCTACAGCAGCGGGGGCGACGGCAGCTCCATTATTGCCGAAACAAACGAAGGTGGCTGCTGTGGCTAACAGAGTCGGAGGAGGAGGGCGGCAGGAAAATAAGTATCCCCAGACTATAGCGGTGGTCAAGGGCAAAAAATATGTCATGGTTGCAAAGCCGCTGACTCTGCCCAACGAGCATGTCAATGACATCGAAAATGATTTGAAACAAATCAATGAGAGCATACGCAAGAACCGCAAACAATCAAACAATTCGCTGGATGGTGGAGGCGCCTTCCCCTCGCTCAACTCTCACAATTCCCTGGTGGTGGATCAGTCCAACAAATTGTTTGCCACAAATTTCTTTGCCAATGTGTCGTACGCCTACGACTCGTTGCTGTGTATactaaaatatctaaaaatacaCGAACGATCCCGGGCCGCTAAGGTCTGCAAGCTGTGGAATTTGGCCGCCAAAGACACTTCGCTGTGGCAAACAGTGCGTATGAAAAACTCTAAGGTTTGCAGTTGGTCGGGTTTCGCTGCCGCCTTGAGACGGGGCGAGACCAAGCATTTGGATCTTCGCAAAATGCTGCAGCCCAGTAGTCGCAGTGAGGATTTGTGGAATGATTTCTGTCAAAATATTGGCACTGTCTGCTCGCTGGAGAACATCGATCTTTGCCGCTGTTCTTTCCGTGTGGTGGAGAGTTTATTCCAGAGCAATCGCAATTTGCGTGTAATCAATGCACTGGCTATCAATGATGATGCTATAAATCTCGAACATGTTGCTCTGGTCAGCTCATTGGAGGAATTGCGACTACGTACTTGTGAGTCGGGCGTTTTGGCGGGTGATCTATCACCCACTGCCTCCCTAAGCAAGCTGACGCATCTCTCGTTGACCTCTGTCAAGGGCCTGGGCGACAAGTGTGTAGAAGTACTGGGAGAACTTACCACTCTCAAGTCACTGGAGTTGGGCGAGTGTGGTGATTTTGATTCCACCTTTGCCTTAGCTGTATTACCCAAACTAATCAATCTGCAACGATTACGCTTGGAAAACGGCACAGTGACAAATGTGTGCACACTGGAGATCCTCGATGCGGTCGCCCGTCTGGTGCAGCTGCATCAACTGGAACTGGTTAATTTCGATATCAAGCCGGGCTTTGATGAAAGGTTAAGTTTATGTATGAATATAACAAAACTACTGATCATTCCCACCTACATCTCCCAATCGGCCACCACCAATCAGATAGTACTCAGTGCCGTTCAACAAGTGGCCGACAGCCTGAAGGTATTCACTTGGTGTGTCACCGTTGAGCTGTTGCGTGTCACCGCCCTCTACGTGGATCAGTGTGAAGAGTCGgcgaaaaaggaaaaacatcaCTTTGATGAGTGTATACCGGTGTTGAAACCGGTGCCAGGCGCACCGCCGGCCGAGGCAGACGACGACGACCAGCAGGAGGCCGAAGTGAAACCAGCCAACAATACGGAAACTCCCGCCGAGGGAGACGATGCCGATGTaccacaaattgaaattttacctTTGGACAAAGTAGAGACAATATTGTCGGAAAATCTACCGGATACCAAGTTCACCATTGTCAAGGTGCCCTACCATGTGACGTGtaaacaacaattggtagattAA
Protein Sequence: MEVDDAIVVMTEPTASSAATTADNDKTVLGGTEGGEPADQTTPSSSSAKQKRAKLKHDKEEPPGGDVDIHNNDSVLTATPFKLEVSGSEDERDNDGDADDNNGADGVTRTAIRRKLLSTPLEDDGSANDGLEELQEVSVKRKRYEVRRSGSEECLLGFDELSGEAQLIKAEVEEKAPAAKENLIVDTTPAVVHEVAMNSPKSVKKTPPQKVAQSPSQNNTRSSSRSPMGAKPKSPQQESPPQNKSVQKTPPKPHIVADGEETNGTADVKPAVQTPPSAGKKPLSPKDDYYRKPFDYGWKRELVWRANLETSKDKADVYFISPAGKKLRARNEIIPLLEGDLTIDHFCFIREPLGASADLETVRSAKPSSRASVTTATLAAAPSPPIVGKRVSKPKGPKGASPPPQGWTPSKALKVNNAALLSSGGGGGRLSLSAQHHHQPQQPLGTALGSRRLENSGQNISHSAKSSKTKKLSAQSSGAKADGHPSYDVRRAAVRSELKESCNIGCVKATGQLPQLQCTKCFCLYHHECVGIDRNTSDFRTTSSTHGREYICEGCVPKPLPKNSNQSSQLTPVNAPMPAPTAAGATAAPLLPKQTKVAAVANRVGGGGRQENKYPQTIAVVKGKKYVMVAKPLTLPNEHVNDIENDLKQINESIRKNRKQSNNSLDGGGAFPSLNSHNSLVVDQSNKLFATNFFANVSYAYDSLLCILKYLKIHERSRAAKVCKLWNLAAKDTSLWQTVRMKNSKVCSWSGFAAALRRGETKHLDLRKMLQPSSRSEDLWNDFCQNIGTVCSLENIDLCRCSFRVVESLFQSNRNLRVINALAINDDAINLEHVALVSSLEELRLRTCESGVLAGDLSPTASLSKLTHLSLTSVKGLGDKCVEVLGELTTLKSLELGECGDFDSTFALAVLPKLINLQRLRLENGTVTNVCTLEILDAVARLVQLHQLELVNFDIKPGFDERLSLCMNITKLLIIPTYISQSATTNQIVLSAVQQVADSLKVFTWCVTVELLRVTALYVDQCEESAKKEKHHFDECIPVLKPVPGAPPAEADDDDQQEAEVKPANNTETPAEGDDADVPQIEILPLDKVETILSENLPDTKFTIVKVPYHVTCKQQLVD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00817426; iTF_01231584; iTF_00679497;
90% Identity: -
80% Identity: -