Basic Information

Insect: Hydropsyche betteni
Gene Symbol: Hr39
Assembly: GCA_028571205.2
Location: JAOXNN020000090.1:968385-972202[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3 3.1e+05 -9.1 12.2 106 148 329 389 201 452 0.48

2 3 9.5e-12 9.6e-07 32.6 0.3 1 137 556 692 556 709 0.56

3 3 5.8e-68 5.9e-63 217.7 0.0 207 408 710 909 705 909 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3	3.1e+05	-9.1	12.2	106	148	329	389	201	452	0.48
2	3	9.5e-12	9.6e-07	32.6	0.3	1	137	556	692	556	709	0.56
3	3	5.8e-68	5.9e-63	217.7	0.0	207	408	710	909	705	909	0.96

Sequence Information

Coding Sequence: ATGACCAGCACGACAACTGGAAATTCTATGCCCGATACGGGCAATAATAAAGCAGATTTAGTTGGACAAGGATCTGGTATAGGATCAGCTTTAAGTGGCGGGAGAAACGTTTCAGTCACACCAATCAACATGAGTGACACACAATTCAACAACGGACAATTCTCTTATAGTTCGAACGGTATTCGTATCAGTGTCCCTTCTGAAGAACAACGCAGAATGGGTGGCAATATCAGCATCGAGGATGAAGATTCTAATGATGCAGAAGTTTCAAAGATTGACTTCTCACAACATCCTtatcaagTTAATATGCGAACTAAGAAGAAAAGACCTTCTTCTAGTACTCTTTCGTTTAACGCTGATGGCCAACCTCAAGATAACGGTACAGTTGGGAGTGATAGGGATCGCGAACGTCCCATGTCTTGGGAAGGAGAACTTTCAGATTCTGAAATGTTGGTAGATTCCAATCCATCTGGTACACCTGACGCATTACATGGTACAAATAAAACACCCCATTCGGATTTAGAATTTAGACTAGGACCCCAAAAAGaagGCAATGGTTATTGCTTGAAAACTGAACCAATAGAAAGAGATAATTCGTTTGCTGCAGCCAATAGACATAATTCTGTTTCATTTCAAAGCCTGAATGATCACGATGCtctcaatttgaaatatggtaACTCTCACCATCCCATGTTACAAGCACATCAACGTAGTCATAGTATGAATAgggtatcaatattatcgaatgataataatttagatatcaAAAGCTCACCACTATTACAACAAAAGTCAACACAAGAAAATATAGACGACGAAAATCCATCTgaaccaataataaaaaatatgcctgtaaatattatacctaAAACTTTAAGCAATAAAATGGCATCTGAAGCCCAAGCATATGCAGCCAAAAGAGAACTGATGCAGCAAACTAATATATCCGAAATCAAACCAGAACTACCTTGTTTAGTAGACAAGTTTTTAGGAGGATATTCTCTTCATAGCACACCTAGTAATTCTCCTCTTTTAAACAGACATcataaaatagtatcaaatCCCAGTACTGATTCTGCCATCCATTCTGTTTATACGCACAGtgtTTACAGTAGTCCTTCGGCAAGTCCTGGAGCTACGAGACACGCTCAATACACACCATCGCTGTCTCGTAACAACAGTGATGCTTCACATTCATCATGTTACTCATATAGCTCTGAATTTAGCCCAACTAATTCGCCTGTTCAAAGCCGTCATCCTATTCCCAGTCATCCAGCAGCACATCATTTGTTTAGATCTGAACATGGAGCATTTGCTCGTCAAACAAGCACGACGACTTCATCCGGTCCCCTCGAAGGGTGTATTGAAGGTGGGGCTGGAAGCCCTGATCCTGAAGGTTCTGATGATCGCATGCATCATCATCAGGGCGTCAGTAGACAACAATTAATCAACAGCCCTTGTCCAATATGTGGTGACAAAATCTCTGGCTTTCATTACGGCATATTTTCGTGCGAATCGTGTAaaggatttttcaaaagaactgTACAAAATCGAAAGAATTATGTTTGTTTACGTGGTGCAAATTGTCCTGTTACTGTTGCTACTAGGAAAAAATGTCCTGCTTGTCGATTCGATAAGTGTCTTCATTGCGGAATGAAATTGGAAGCTATCAGAGAAGATAGAACGAGAGGTGGTCGATCTACATACCAATGTTCATACACGTTAAGCAGCGCAGCTTCTACTAGTTCACTTCTAGGCACTGGCCTTCAGTCTGGTCCTTTACGCCATGCATCTAGTCTGACCTCAGTGAACGGACCATCATCACATTTGTCGTATCACTCACATCATGATTTACATTCAGCTTCTTTAAATTCTATGCAATTACCTTTGAGTAGACTTGCTCAATCTGGTGTGAAATCTGAACCTGGAAGTCATGCGAGTCAGGCTGAAAATATTGGAGTGCCGCCATTATTGCAGgaaataatGGATGTTGAGCATCTCTGGCAGTATAATGAATCTGAATTGACTAGGCTCAATAAAGGTCAACCCGTTGGTTCGTCCACCATGGCACCTAATCCCGCTAATAATCCACTTTTGCATGCAGCTGGTGTTCCAGCAGATGCTTCTCctgattttctttcaaatctttGCAATATAGCAGATCACAGATTATACAAAATAGTCAAATGGTGTAAAAGTTTAcctctttttaaaaatatatctATCGATGATCAAATATGTCTGCTGATTAATAGCTGGTGCGAACTTTTAGTTTTGTCATGTTGTTATAGAGGAGTTAGTACTCCTGGTGAAGTGAGAGTTGGCGGCGGAAATCGCGGTATAACACTTCAACAGAGTGCAAAaaTGGGACTCACACCTTGCATAGAGAGAATGTTGCATTTTACTGATCATTTGCGAAGGTTAAGAGTGGATCGTTATGAATATGTTGCCATGAAAgtcattgttttgttaaattcaGACACCTCTGACCTGAAAGAACCTGAAAAAGTTAGAGCTTCCCAAGAAAAAGCTTTGCAAGCTTTACAGGCTTATACTTTGGCTCATTATCACGAAACTCCTGCAAAATTTGGTGAATTACTTTTGAGAATACCAGAATTGCAGAAAACTTGTCAAGTTGGTAAAGAAATGTTGAATCCGTCAAATAAGAACAAAGATGGTGAGACATCAAGTTTCAACTTACTGATGGAACTGTTACGAGGTGACCActaa
Protein Sequence: MTSTTTGNSMPDTGNNKADLVGQGSGIGSALSGGRNVSVTPINMSDTQFNNGQFSYSSNGIRISVPSEEQRRMGGNISIEDEDSNDAEVSKIDFSQHPYQVNMRTKKKRPSSSTLSFNADGQPQDNGTVGSDRDRERPMSWEGELSDSEMLVDSNPSGTPDALHGTNKTPHSDLEFRLGPQKEGNGYCLKTEPIERDNSFAAANRHNSVSFQSLNDHDALNLKYGNSHHPMLQAHQRSHSMNRVSILSNDNNLDIKSSPLLQQKSTQENIDDENPSEPIIKNMPVNIIPKTLSNKMASEAQAYAAKRELMQQTNISEIKPELPCLVDKFLGGYSLHSTPSNSPLLNRHHKIVSNPSTDSAIHSVYTHSVYSSPSASPGATRHAQYTPSLSRNNSDASHSSCYSYSSEFSPTNSPVQSRHPIPSHPAAHHLFRSEHGAFARQTSTTTSSGPLEGCIEGGAGSPDPEGSDDRMHHHQGVSRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGANCPVTVATRKKCPACRFDKCLHCGMKLEAIREDRTRGGRSTYQCSYTLSSAASTSSLLGTGLQSGPLRHASSLTSVNGPSSHLSYHSHHDLHSASLNSMQLPLSRLAQSGVKSEPGSHASQAENIGVPPLLQEIMDVEHLWQYNESELTRLNKGQPVGSSTMAPNPANNPLLHAAGVPADASPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGNRGITLQQSAKMGLTPCIERMLHFTDHLRRLRVDRYEYVAMKVIVLLNSDTSDLKEPEKVRASQEKALQALQAYTLAHYHETPAKFGELLLRIPELQKTCQVGKEMLNPSNKNKDGETSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01218384;
90% Identity: iTF_00815848;
80% Identity: iTF_00815156;