Hcul007392.1
Basic Information
- Insect
- Hybos culiciformis
- Gene Symbol
- spopl
- Assembly
- GCA_964007475.1
- Location
- OZ023273.1:58771503-58782680[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.32 69 4.2 0.0 5 30 142 167 138 177 0.89 2 4 8.7 1.9e+03 -0.4 0.0 63 88 359 386 347 406 0.76 3 4 4e-15 8.7e-13 49.0 0.0 22 106 806 891 796 895 0.92 4 4 4.9 1.1e+03 0.4 0.0 81 109 898 926 890 927 0.85
Sequence Information
- Coding Sequence
- ATGGCTCCAGAGCATAATTTTTTGGGAACTTGGGAAatattcAAATGTACATTTGAAGGAAATGATGAAACTTGGATTTCTGGACTTGAAGgGATAAAGTTCAGATTGGATGAAAATAATgacataacattttataatgaTTCAGTCAGTCATAGTCCGGATGcgcaaaataaagaaaaaatatgtgCGAATTGCGATTCTGCAAGTGTCCTTTTTAGTTGTGAAACATTTGATGTTAACGAAGAAAACCCCAGGTTGATATTTGGAGCGTTTGCTGGCCATAGTATCGAATTTAATataaaaacgTTAATGCCTACCGATGAATTGATATTAGATTGTGAAAATTGGTATACCATTCATTGTAAGCGTTTAAAAAATGATCATGTAGTTGgacaagaaaaacaattttcattaggAGATGCATTGAAAGATACTTTTTTTAGTGATGTTCTTATTACGAGCTCTGACGGTATAGAGTATCACTGTCATTCCATTATATTACGTTTAAATGGTTTTGACTGTAGTATGTGCTGTGAACAACTAGAGTCAccaattttaagtgaaaattttagTGATGTTGATGAAAAATCAcccaaaaatatacaaattgcAATAACTGATTTAGGTGATGATGACACCAAGAATGATATCGATGATGATAATTCAACAATAAACGAAAGCAAAAATTTACCAACTACATTAAATTTATCGCCTACGTTTCTCCAATTACCTGGAAGTTACGATAACATGAGTTTatgtaaaaagaataatttgtcTACGTCATTCAATTGTTTGAATATTTCGACAgggaaaaataatcaaaatatttctgGCAGTAATCTAAATAAGTATAAAACGTCATCAGATTCTAATCTTCAAAGCAATTATGTGAACTcgagaaatatttttaacttttccaaTGAGATTTATTTGAATGCATCATATGAGAATAGCTCGTGCTGCAACAGGAAGCCTCCATTATCACCATATAAAGCAAAATCATTGTTTCCGTTTGATACGCCACCAAATTCTCCATTAACACCAGTGAGCGTATTGAATAATTTACCATCATTTATGTTGGCGCCTATTGTAAATTGGATTTACACGGAATCATTAATAGCAAATATGAATGAAGATACTTGCGAGAAACTTATAAACTTCTCAGAAACACAGccttcattaataaaattagttgaGCCTTGTCGAAAATACCTTAAATTAATACGattaaaaaaagtcgttattgatattataatgaatattcatagtattataaacaaaataattcaaaaaatcagCCCATCAAATATAAGAACACAACCAAATTTATTGTTTGGAACATTTAAAGAATGCTTGAAAGATGGTGCTATAGGTTGTGTTAAAATTCTACAATTCtgcaatttatttgtaaaagacATTTCTGATATAACTCGtaatcaaaaaaatgaaattattaaatatgttcGAACCAGAATTCCAATATTTTTGCAGCAAGTtcatcaattattaaaaaatatattagaagttttgataaatttggatgATGAGAAAAAAGCAAAATTAGTCACATATCTAGTACCTGAGattgaGTCTTCATTCAAAGTTATCACTAATGTTGTTGAAGAAGTAAAAAATTCGTTGGAAAAACTttgtaaagatCTCAAATGCTCGCATTTGGATTTATCCATGAAAAAAGAAtgtaaaactaatttaaatgagGAGAATCAAGCGTTATTTTCATCAAACTTTAATTTCGCTACTTCAGATAAAAATGTTGTAgagaatgatttaaaatttgttctttaCATGTACGAAGTACGGAAAATGAGAGACGTTTACGGTCGAATATCAACAATGTTGGAAATACTTAAAGAAAAGAAGACATTATTTTGTGAAATGAATTTTCTAGATAAAAGGAGCACAATAAACCAAAATTTGGAACAGCTTATTTTAGAAATTCCGAATTATATTCTCATTATAGAAAACATATCGGATAGATTTGATGAAAAACTGGGTTGGAAGgaatttaagttttgttttaagTTAGCTACAAGTCAAATTaatggagtaataacaaaattattagatCATAAATCAGCTTTAGTTAACTCTTTGAGCCAAatttgtaatttggttcaaaaagacgaatttatattttccttaaGCGAATTAGGATTTTTACAGAAATCAAATGACATTCAAAATGAATCTGGAAGTGAGGATAAAATTAgatatgattataaaaatattaagttgaatttagtgaaaaatttatgtgaacCACCAATTACAGTCAATAGTGTTTTGTCAAAAAATGCATTAAGACTTCTTCATTCAGGACAACTAACAGATATGGAATTTGAAGTTCGTCCAAGCAATGGAGACAGCAATAGTTACATATCAAATAAAAGTCTCATCTTTCGAGCTCATAGGATTATAATATCAACAAGatgcGAATGGTTTAAAAAAGCATTACTTTCGGGCATGATGGAGAGCATTACTaggaaaattattataCCTGATACATCACCTGTGATATTTCGTCGcttattactttatttatatgGAGCTCCGATTGATAAAACAGTGGGTGCCGAGCAAATTTGCGAACTGATGTTGTTAGCAGACAGATACTCTGTAGATGATTTGAAggaatTATGTGAAAACTCATTGAATCTTTTAATTGATGAGTACTCGGTAGTTTGTTTACTAGGAATAGCTGATCGTTATGGAGCTTCGGTATTGAAATCAAAATGTTTATCGTTTTTGTCACAACATCctaaattaactaaattagatatttttgagGAATTACCAAAACAAATTCAgCAAGAAGTAAAGGATTTAATACATTGGCAAGGAAGAGTTCCTCAACCTTGGAGTAATGTGAAAAGGCAAAGCTTGAAAAGTCCTTCACGCGGCAAATCTAGGTCTAGAAGAGCATCACCATCATATATGTGA
- Protein Sequence
- MAPEHNFLGTWEIFKCTFEGNDETWISGLEGIKFRLDENNDITFYNDSVSHSPDAQNKEKICANCDSASVLFSCETFDVNEENPRLIFGAFAGHSIEFNIKTLMPTDELILDCENWYTIHCKRLKNDHVVGQEKQFSLGDALKDTFFSDVLITSSDGIEYHCHSIILRLNGFDCSMCCEQLESPILSENFSDVDEKSPKNIQIAITDLGDDDTKNDIDDDNSTINESKNLPTTLNLSPTFLQLPGSYDNMSLCKKNNLSTSFNCLNISTGKNNQNISGSNLNKYKTSSDSNLQSNYVNSRNIFNFSNEIYLNASYENSSCCNRKPPLSPYKAKSLFPFDTPPNSPLTPVSVLNNLPSFMLAPIVNWIYTESLIANMNEDTCEKLINFSETQPSLIKLVEPCRKYLKLIRLKKVVIDIIMNIHSIINKIIQKISPSNIRTQPNLLFGTFKECLKDGAIGCVKILQFCNLFVKDISDITRNQKNEIIKYVRTRIPIFLQQVHQLLKNILEVLINLDDEKKAKLVTYLVPEIESSFKVITNVVEEVKNSLEKLCKDLKCSHLDLSMKKECKTNLNEENQALFSSNFNFATSDKNVVENDLKFVLYMYEVRKMRDVYGRISTMLEILKEKKTLFCEMNFLDKRSTINQNLEQLILEIPNYILIIENISDRFDEKLGWKEFKFCFKLATSQINGVITKLLDHKSALVNSLSQICNLVQKDEFIFSLSELGFLQKSNDIQNESGSEDKIRYDYKNIKLNLVKNLCEPPITVNSVLSKNALRLLHSGQLTDMEFEVRPSNGDSNSYISNKSLIFRAHRIIISTRCEWFKKALLSGMMESITRKIIIPDTSPVIFRRLLLYLYGAPIDKTVGAEQICELMLLADRYSVDDLKELCENSLNLLIDEYSVVCLLGIADRYGASVLKSKCLSFLSQHPKLTKLDIFEELPKQIQQEVKDLIHWQGRVPQPWSNVKRQSLKSPSRGKSRSRRASPSYM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -