Basic Information

Insect: Hormaphis cornu
Gene Symbol: Hr39
Assembly: GCA_017140985.1
Location: CM029363.1:22833409-22839010[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3 2e+04 -8.4 14.9 38 100 191 257 114 337 0.47

2 3 1.4e-07 0.00092 18.9 0.1 1 68 404 472 404 515 0.77

3 3 2.5e-71 1.7e-67 228.8 0.1 202 408 513 714 462 714 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3	2e+04	-8.4	14.9	38	100	191	257	114	337	0.47
2	3	1.4e-07	0.00092	18.9	0.1	1	68	404	472	404	515	0.77
3	3	2.5e-71	1.7e-67	228.8	0.1	202	408	513	714	462	714	0.92

Sequence Information

Coding Sequence: ATGGCCAACGCCAGCGACGCCAGGATGTGGGGCCACAGCGTTCAGGTATCGTCCGGACCGGTCACCGTGACGTCGATCAATCTGATCGCCCCGCGCCTGCAGCCCAACGCGCAGATCACGACGATTAAAGAGGAACCTCATGAGAAGGATGGTACGATGACCGAATTAAAAGAAGACGTCATTGACGGTTCTGAGTGTGACCGGGAAGTGAGCAAGATTGATTTCTCCGGAGTCACTATGAGGAGTAAAAAAATGAGAGCCGTCGAGGAAAACATGCCCCGGCCTATGTCTTGGGAAGGTGAATTATCCGACACCGAAATGAAACCGGAGGAAGATCGCACTGTAGACATGCGAACTGTAAATCAAAATTATTTATTGCAGCAAAATGAAAACATTAATAACCAACAAGAATCGACAGTAAAACGAATTGTTTACAACGATAACAACTTGGTTGATCGAGTGATGGACCATGTTAAAAGTAAAGTAACATCGTCGAACAACGAAATCCCATTGCTCGTAGATAAATTGTTGGGTGGTGGGTATAGTCCATTACTGCAACACAGAACTACTAATGGAGTCAAACAGCAGCCATCATCACATATTCCACAAACTCAGAGTCCAGATTCGGCCATTCACTCTTGTTGTTCCCCTGCACAGTCACCCATCACATCAAGACATAATCCTCCGTCATCTTCAGGGTTTTCATCCCCATCCACATTCACACCATCTTCGTTGTCGAGAAATAATAGTGATGCATCTCAATATGGCGGATCACAGCATAGTTCTTGTTACAGTCAAAGCTATTCTTCAGTGTCAGTTTCACCTACACAGTTTTCCCCGACACAGTCTCCTATCCAGCCGAGACATGTGCAAAGAAATTTCCACGAGTATACTGTGACTGAAGAAACTAATGGGTATGAAGAGAAAATGTCGATGTCCGATATCAGTCAACAACATGGCATAACATCCGGTATTTCAAGACAACAATTGATCAATAGTCCCTGTCCGATTTGCGGTGATAAAATTTCTGGCTTTCACTATGGAATATTTTCATGTGAAAGTTGCAAAGGGTTTTTCAAACGCACTGTACAAAATCATAAGAACTATGTTTGTTTACATGGTTCAGCATGTTTGATTACAATCGCTACGCGCAAGAAATGTCCAGCGTGTCGCTTTGATAAGTGTTTAAACATGGGTATGAAACTTGAAGCAATCAGAGTTGACAGAACAAGAGGAGGACGTAGTACTTATCCGTTTACATATACAATACCTTCATCTAATATTCAGCCACAGCATAGTGGACAGCATTCTGGCATGGCTAACAACTCTGTAGATAATAAAGTTAAACAAGAAGAACGTGCGTGCAGGTCTCCGCCCCAAGAATTACCCAGACTGATCCCTCAATTATTGCAAGAAATAATGGAAGTGGAACATTTATGGACTTACAATGAAGGCTCATTTGAATCATCAAGTGCTAGTGGAAGTTCAATAAACCATTGTGGTGGCGCCAAAGAAATAGCAAAAAGTCGCTTAATGGCTGAAAACTCAGGAACAGACTTTCTATCTAATTTATGTAACATTGCTGACCATCGACTGTATAAAATTGTCAAATGGTGCAAATCATTACCATTGTTTAAAAACATTTCGATTGACGATCAGATATCGTTATTGATAAATGCCTGGTGTGAGTTACTGTTGTTCAGTTGTTGTTATCGGTCAGTAAGCAGTCCGGGAGAAATACGGGTCAGTCTGGGCAAGTCTATTTCTTTGGATCAAGCTAGAGAATTAGGTTTAGCACCTTGTATTGAGCGTATGTTGAATTTTACACAACACCTGAGACGCCTGAAAGTGGATCGATATGAATACGTTGCCATGAAAGTTATTGTTCTCTTATCGTCTGATACGAATGACTTGAAAGAACCAGAAAAAGTTCGTGCATCTCAAGAGAAAGCATTACATGCATTACAACAGTATACTCTGTCACATTATCCAGACATGCCGTCCAAATTCGGAGAACTGTTATTGAGGATACCAGATTTACAACGTACTTGTCAGGTTGGAAAAGAAATGTTGTCAATAAAAAGCAAAGAAGGAGAAGGACAAAGCTTCAATCTCCTAATGGAGCTATTGAGAGGAGATCATTAA
Protein Sequence: MANASDARMWGHSVQVSSGPVTVTSINLIAPRLQPNAQITTIKEEPHEKDGTMTELKEDVIDGSECDREVSKIDFSGVTMRSKKMRAVEENMPRPMSWEGELSDTEMKPEEDRTVDMRTVNQNYLLQQNENINNQQESTVKRIVYNDNNLVDRVMDHVKSKVTSSNNEIPLLVDKLLGGGYSPLLQHRTTNGVKQQPSSHIPQTQSPDSAIHSCCSPAQSPITSRHNPPSSSGFSSPSTFTPSSLSRNNSDASQYGGSQHSSCYSQSYSSVSVSPTQFSPTQSPIQPRHVQRNFHEYTVTEETNGYEEKMSMSDISQQHGITSGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNHKNYVCLHGSACLITIATRKKCPACRFDKCLNMGMKLEAIRVDRTRGGRSTYPFTYTIPSSNIQPQHSGQHSGMANNSVDNKVKQEERACRSPPQELPRLIPQLLQEIMEVEHLWTYNEGSFESSSASGSSINHCGGAKEIAKSRLMAENSGTDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCYRSVSSPGEIRVSLGKSISLDQARELGLAPCIERMLNFTQHLRRLKVDRYEYVAMKVIVLLSSDTNDLKEPEKVRASQEKALHALQQYTLSHYPDMPSKFGELLLRIPDLQRTCQVGKEMLSIKSKEGEGQSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00340610;
90% Identity: iTF_00941576;
80% Identity: iTF_00812008;