Basic Information

Insect: Horisme vitalbata
Gene Symbol: Prdm9
Assembly: GCA_951804965.1
Location: OX638094.1:2939522-2946209[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00033 0.026 15.8 6.4 1 23 347 369 347 369 0.97

2 10 0.0016 0.12 13.7 1.0 1 23 375 397 375 397 0.98

3 10 2.6e-07 2e-05 25.6 2.5 1 23 403 425 403 425 0.98

4 10 6.2e-07 4.8e-05 24.4 3.3 1 23 431 453 431 453 0.98

5 10 1.9e-07 1.5e-05 26.0 3.1 1 23 459 481 459 481 0.98

6 10 1.9e-07 1.5e-05 26.0 1.7 1 23 487 509 487 509 0.98

7 10 9.7e-06 0.00076 20.7 3.6 1 23 515 537 515 537 0.98

8 10 1.9e-07 1.5e-05 26.0 1.7 1 23 543 565 543 565 0.98

9 10 6.1e-06 0.00047 21.3 3.7 1 23 571 593 571 593 0.98

10 10 7e-06 0.00055 21.1 3.3 1 23 599 621 599 621 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00033	0.026	15.8	6.4	1	23	347	369	347	369	0.97
2	10	0.0016	0.12	13.7	1.0	1	23	375	397	375	397	0.98
3	10	2.6e-07	2e-05	25.6	2.5	1	23	403	425	403	425	0.98
4	10	6.2e-07	4.8e-05	24.4	3.3	1	23	431	453	431	453	0.98
5	10	1.9e-07	1.5e-05	26.0	3.1	1	23	459	481	459	481	0.98
6	10	1.9e-07	1.5e-05	26.0	1.7	1	23	487	509	487	509	0.98
7	10	9.7e-06	0.00076	20.7	3.6	1	23	515	537	515	537	0.98
8	10	1.9e-07	1.5e-05	26.0	1.7	1	23	543	565	543	565	0.98
9	10	6.1e-06	0.00047	21.3	3.7	1	23	571	593	571	593	0.98
10	10	7e-06	0.00055	21.1	3.3	1	23	599	621	599	621	0.98

Sequence Information

Coding Sequence: ATGACACAGCGTAGTTTGCGGCAGCGGCCGCGGATAAGCTACTACGAGCCAGAAGAACCAGATTTAGATGAATATGTGTtttgtgAGAAATGTGGAGATTACGTATACGAGTACTGTTCCATACATGGACCCCTACTAGTCATACCAGATAACAAGGTTCCCGCCAAACCCGATGTCCCATGGTTCGTCCCTCGTGCAGCCCTCACTATTCCCGACACTTTTCTACACATCCATTATTCCATTATACCAGATGGAGGGCTGGGAGTGTTTTCATCAATGACGCTACCATCTGGGGTGCGGTTTGGACCGTATATTGGACAGCGTACTGACCTAGTCGAGTCCGCCTACTGTTGGCAGATTTACGACAAAAACCGCAAGCCGCTTCACTGCGTGGACGCAGCTGACGCTAACAAGTCTAATTGGATGCGCTACGTGAACTGCGCAAGGCACTGGCAGGAACAGAACCTTGTGGCGTACCAGTACCAGGGGGAGTTGTACTATAGAACGATCAAAATAATACCTCGCTTTACGGAGCTCATGGTATTCTACGGCAGTGAATTTGCGTGTGAACTGGACGTGGACCTCGGGAACTACAACTCACCGATAGGATACGCGCAAAAATTCGGTGCACCGATCGTTAAGAAACGTAAACCCAATGTTGACGACACGAAAATGCATGGAGAAACTAAACCAGCAAGCGCCGAGACTGCTAACATACTAACAACAGATGAAGTAAAACTGACTTCAATAGTTGAAGATTTGGAGACTGCTATGAAACAAAGCTAcgacaaaaataaaatgcctAAACAAACAATCAATACTGAAGCCAAAAACagcataacaaataaaaataataaagtcaaAAAGACCTTTGCAGCTaacaagaaagaaaaatataaattcgtcacaaagaaaaatataaattctaaaAAACAGCAGACAAGACAGAACAACACTTCAATAGTAACATCAGATAcacaaaaaatcttaaaaccAGAAACCAACACTAGCAACAAAACAAATGGCTTAGACCCGTATTTCTATTGCAACGACTGCAACAAGAGATGTGTATCTAAGAAAGATCTGCAAAGGCACTTCAGGTTTCATGATTTAGAACGGGCTTATGAGTGTGATATTTGTAAATTAAGGTACATTTCAATACATGATTTAAATCAACATAATAGGATACACTCAAAAGAATTGCGATATCACTGCGAAATATGCGACAAAAAATTCACTCGAAGCGGTTTTTTAGAAATACATATGAGAACTCACACAGGAGAAAAGCCATATCACTGTCAAATATGTGACAAAAAATTCACTCGAAGTGGttcattaaaaatacatatgaCAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGCGACAAAAAATTCATTGAAAGTAGTAATTTGAAAAAGCATCTGAGAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGCGACAAAAAATTCACTCAAAGTGGTTCTTTAGAAATACATCTGAGAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGCGACAAAAAATTCACTGTAAGTGGTTCTTTATATAAACATAAGAGAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGCGACAAAAAATTCACTCAAAGTGGTTCTTTAGAAATACATCTGAGAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGctacaaaaaattcaataaaagtggtaatttgaaaattcatctgaGAACTCACACAGGAGAAAAGCCATATCACTGCGAAATATGCGACAAAAAATTTACCTACACAGCTCAATTGAAGTCACATCTGCAAACCCACATCCACGCGCGAGCCGCTTGA
Protein Sequence: MTQRSLRQRPRISYYEPEEPDLDEYVFCEKCGDYVYEYCSIHGPLLVIPDNKVPAKPDVPWFVPRAALTIPDTFLHIHYSIIPDGGLGVFSSMTLPSGVRFGPYIGQRTDLVESAYCWQIYDKNRKPLHCVDAADANKSNWMRYVNCARHWQEQNLVAYQYQGELYYRTIKIIPRFTELMVFYGSEFACELDVDLGNYNSPIGYAQKFGAPIVKKRKPNVDDTKMHGETKPASAETANILTTDEVKLTSIVEDLETAMKQSYDKNKMPKQTINTEAKNSITNKNNKVKKTFAANKKEKYKFVTKKNINSKKQQTRQNNTSIVTSDTQKILKPETNTSNKTNGLDPYFYCNDCNKRCVSKKDLQRHFRFHDLERAYECDICKLRYISIHDLNQHNRIHSKELRYHCEICDKKFTRSGFLEIHMRTHTGEKPYHCQICDKKFTRSGSLKIHMTTHTGEKPYHCEICDKKFIESSNLKKHLRTHTGEKPYHCEICDKKFTQSGSLEIHLRTHTGEKPYHCEICDKKFTVSGSLYKHKRTHTGEKPYHCEICDKKFTQSGSLEIHLRTHTGEKPYHCEICYKKFNKSGNLKIHLRTHTGEKPYHCEICDKKFTYTAQLKSHLQTHIHARAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00811630;
90% Identity: iTF_00811630;
80% Identity: iTF_00811630;