Hvit014224.4


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Horisme vitalbata
Gene Symbol
BAZ2B
Assembly
GCA_951804965.1
Location
OX638094.1:23236718-23310103[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.5e-09 1.9e-05 25.1 0.0 3 76 677 753 675 754 0.87

Sequence Information

Coding Sequence
ATGGACAAGGAGAGCGGCGATGGTGCCGACTCGGCGGGTAAGGCGCCCGATGCCCTCTCCGCCCTCGACGCAGCTGGGCTGTTCAATGCCTACTACGGCATGGGGAGGGATGGGTCTGGTGCTGGCGGCGCGGCGGCACAGGCGCAGGCGCAAGCCCAGGCAGCACTGTTCGGGTTCGGATCCCGCTACCCTCCGCCCACCACCCTGGGCGTGGCGGCAAATCAGGCCGCCTCGCTGGGGCTGCATCCCGCTGCTACACTGTTCGGGTTCGGATCCTGCTACCCTCCGCCCACCACACTGGGCGTGGCGGCGAATCAAGCCGCCTCGCTGGGGCTGCATCCCGCTGCTAGTGCAGCATGGTGGTCGATGGCGTCTCATCTAGCTGCGCAGGATTACCTAGCGAGGATCCAGACAGCTGGTCTGCAGGGTTTCCCTCCAATGGGGGACCCGTACTCCACGCTCTCGGCTCTCTCAGCTGCTGGCATGAAGCATCCACAGAAGCAGAGTAAACCTGCTAGCAGGAATGAAAGATCCGGCCGAAGCAGTACATCATCCAGTGCGTCCACGAAGGAGAAGAGTCCGTCAACGAGCAACGCCAACTCACAGCCGAATCTCAGCGATTGGGCGTCTACGTACGGCTTTCCGAAGACATCGTCACCGTCCACTATGCACTCCCAATCGCTCTCCAGTTTGGCTTCTCTGAACAGCCTCGTGTCATCTCCTCATCAGAGCAAAAGCAAGCAGCAACCGCCTTCCCACTCCCAGTCACGTaaacagtcatcatcatcaacatccacGTCGTCCAAGAGCAAAGAGAGGGAGCTAGCTTTACTCCGAGGGGACCTTATGCTGGCTCAAGCAGCGGCTCATGGGGCATACCATGCCGCTGTCGCTCACGCTGCTAAGGGAAAGaACATCCAGAATATGTCATCACTATATCCGTTTGGTATGCCTGGTTCAGATAAAGATCGACATGGTGGGATTGACGCGTTGACCGGACTACCCCACACCATTCTAAGTGCTGCCTTGGAAGGAGGTGATCCAGCGTCGGTGTTGGGAGGTGTGAGGTTACCTCCAGACACTGAAATCATCAAATACACCTCTGCTCTCACCGGCCCAAAGGCACCCCCAGGCACAACAAATCGCGGCAGGAAGAAGACGATATCCCTCGACCCACCGCAAGTGTCTGTACATCCGAGCGCAAGTGACGGACGGGGCACGCCGCTGCCGAGCAAGCGGCAGAAGTTAAGGAACGATGAGTACGGTGCTAGATCAGCAGTGGAAGTGATTCGACTGCCCACTAAGCCGGAGCGACCTGCCAGTGTTGCCGGCACGCCGCCGCCTAACCTCGCAGACTATGCTGGTATTTCCCGAGAACTTCTGCAAACGATAGCTAGTCAAAGTGGTGTCAGCTTAGCGGCGCTGGAGCGGCAGTTAGCGGGTTCGAATACCGGCAGGAGTAAAGacACTGGTCTTAACCTGTCAAAGTCGAATGCTAGTTCCGAAGAAGCTCCTCTAGACCTTGGCTTGAAGAACGATGATGATGCACCCCTCAATCTCTCCTTGAAGCCGACTCCACCGGCGAGTCAAGCGTCAGACGCGTTATCAAGACTCACTTCATTGAGCAGTTCGTTAAATGCATCATCACACAACGACCGGACTTCTCGCAGAAAGCCCGGTGGTCGACCGCGCCGCGTTGTGCCCGAGTTGAACACGTCGGTAGCGGACTCGCCTCGACCACGGTCTAGCGGCAGTGAGGATAGCGAGTCTGTACCCGCCTGGCCGTCGAGAGAAGGCCGACCACGGAACTTAGGCCGCGGAGTCAGCAAACCTAAGAAGAACACCGTTGCTTCACTCCTGGCACAGAGCAGAGCCCTAGGCCTGCGCCCCGCGCTAGCGCAGCAACTGCTGGGAGAAGCTGATCTGGAGAAATTAAAGTCAGTGTTAGGAGAGGCGGCGAGTACCAACTCGGAGTGTTCGTCCGACAGTTGTCCTTCTGACTCCGACGTCAGTGAGGATAGACGGGACCAGGACGCGCAGTTGAGACTGCCCCTTGCACTAGGTTGGAAGCGTGTGACTGTGATCAAAGGTCTCTCTCGGAACTGCAATATAAAAGGAGACGTGACATACGCGCCGCCAGAACCCCATTCCAGCTTCAAGATCACGAATGCGCAGGATTTGCAGACGTTCCTAGAGTCGAACCCCTGTCCGCCGCTCTGCACTGACAACTTCAGCTTCAACGGACGGCATGTGGTGGGAGACTTCGTACAGCCGCCGATGGACTCCGGCGAACCGCTCGTCTTCAACGAAACTGAGATCACTAAGAGGTTAGAGGAAGCGAGAGCTTTAGCTGCATTGACGGGACCAAGACCGACGCCGCCGCCCGTGGACCGGCGCATAGAGCTGGCGCGCCGGCAGCAAGCCGCCAGGGACGCCAGGCGAGACGCCAGCAATCGCTCCAGAGATCAGGCCCGACTAGTCCGCGAACTGGAGAGGTCAGAGAAAGCTGAGATCGTGAAGCGTGAGAAGGAAGTGAGGAGTCAACAGCTGCTGGAGCATATCAACAAGAATAGAACACAGCTGACCATTGAAGCATTGCCAATGCCGAAAGAGCAAAAGACAGAGATAAAAACCGAGAGAAAGGAACGCAAAATGCCACCGATAAGCCTCTCTCTTATACCTGTCAGTGGGCCTAAGGACAACTCTCCTATTAAAATGAATTTCGATAATGATATAGAAGAATATAATGCCTTAGATAAAATGAAAGACTTCGCTGAAAAAGCAGCATTCGATACACCAAAGCGTAAAGACAAATACGACTTTACGATAAAAGAGGGAAACAATATGGATAAGCTAATCGAATCCTATTCGCGGATAAGCGAATTCGTGAACGGCTGTGATTGGTCGAAATCACCGGAGAAGGATCCTAAAAAACTCGAAAGAGATCCGAAATTGGAGAAAAAGTATTTGGAAGCGAAAAACGAGTTTATGTCCCAGAATTTAATGCTAATGCCAAAAAGTAATGCTGAAAAATGCCAGCTCAAAAAAGGAACTGATGTTATTGATTTGAGCGATAACGAGGATAATGATATAACAGATATAATAAGGAAAAAGTTGCAAAAAGGCTGTTTGAATATTGGCAAAGATGGCGCACTATCGATATCGGTACAGCAATGTACTGAGATCGGACCGGCTAAGCGGAAAAAGCAGGAAGATTTGGACAAGCAGAAATTTGAAGAGCAAATTAAGAGGCAACAGGAGAGAGAGATCAAAAGGCAGCAGGCCATGATACTTAAAGAACAGCAAAAGTATATAAACGAGGAACGCGAGAGGAGGCGACAACACACCTCATTCATTCGCCAGCTGGATTCGAGGAGACGATGGGAGGACAGAGAGAGGAGGAAACACCAGAACCTGCTAGACAGGCTGTTGGTGAAAGAGAAGAAGTTGCAGGAGAGGAGGAAAGAGATGGAGCTATTATCTGAGCTGAGACGGCCACAAGAGGACTCTACGTTGTCAGACCAGAAGCCTCTGCCTACCCTCAACCGCATCCCTGGACTGAAGCTGCCGGGGCAAGCGACCGCGGACATTCTACAAGTCTACgagtttattcataactttGGACAGACTCTGGGTTTTGATATGGACTCCATGCCAACACTGAACACGCTGCAAATGGCACTCCTACCGGACTGCTGCGCTGATGCTGAAGAGGAGTTGATACAAGTCCTGACACAGCTGCTTATCACTGCCATTGAGGACCCTGGAATTCCACATCCAGGTCGTCATACAACACTACTCGGGCATGCGATTCGCATGGGCGATATAACGCCGGCCAATCTGAGCGAAGTACTGAGGATATACTTGTACGCGAACGCGACGGGCGAAATCAAGGCTTTGACAGGGTTAACAGCGGAGCGGGAAAGAGATAGAAGAGTAGCCGACCACCACCAGAACGACGCTGAAATGCTTTCCTCAAGCACCAACTCGAAAAACCAAGCTTACTACGAGCATCTACTTAACAACCAAACATACAAATTATCAGTGGCGCTTCGAGACAAGCCTTTCTTGGCTCTCAACCCAACAATGAAGGCGGCCATCTTAGCATTCCTATGCAACGAGCTTTTGCAAAACAAATCTGTGCTGAGACAAATAGACGGGTCTTTGGAACATCTCAACCAGTTGAAGAAGGAACGGTATCTAATGGACATGAAGATACGCAAggtTCGAGTACTACATCAGAGGAAAGTAAGGGCGGAACAGACGGAGAAGCAACAAGCCCTAGCTTTGGAGAGGATGCAGAAATTGGTGGAAGAGAGTACAGCCAATCTAAGTCGGGCCTCGCCACATCCCACCGATGATGAACACCAATCAGAGAAGTCAGAAACGCCGAAAAAAGATGAACATGAAGACGAATCTCCGTTCAAAGATCCTAACAACGATGAGAGTGATAAAGAGATGTCCCCTATGAAAGATCTCAAAGATCTGGCCACCAAGGaactgtccagtatAAAAGAGCTTAGCAGTCGAAGATTAAATAATAACAAGGAGGAATGCTCTCCATCGGAGCATAAGATAGACAAGGACAGCGTTATGGGAGACGAAATGCCGAGTGACTTGGAGAGTGAGGGAACTCAACCAGAAGAGGATGAAGATAAGAACCTATCATCCGAAGAACTATCTAGAAAGTTGGAGAAATTACTTCGACAGTCGGAACAACAGCAGCAACAGCTGATAGCTGGATCTCACGCTTTGAGAGCTACTTGCTATGGACAGGACAGGTACTGGCGTAGATACTGGTCGTTCGGGAAATGCGGTGGTATATTCGTCGAGGGCATGGAATCCGCGCAGCCAGAGATATTGGACTACCACGAGGCCTTGGAGGCAGCGGCCAGTCAGAAGCCGCCTGAAGTCAAGAAGAAGAGAGGTAAAACAGAGAAGAAAGATCTAGACGAGGAAAAGAACCCGGAAACGGAAGCTCAGAAGAAGGAGGAGGCGTTGAAAACTGAACTCGAACTAAAGAACATAAAGTCTGAATTGAATTTGAGCGATCACACGCAGATCATCAAGTACGAGCCGAACCAGGGAGGATGTAAACTAGAGGGTTCATCAATAAAAATGGAAGAGAAATACATCCAGCAGCAACAGAACAGCCAGCAGGACATGCTCGATATCGAGGACTCAATACCCACTGCGTTCCTCGTACAGAAACCCTCGCACAAACCTATGTACGCGCAACAAGCCGAGCCCGTCGATAAGCCGCAGGAAATTGTCAAGGTTGAAAATGTTGTGAAGACCGAGGAAAAGGAGGAAGAAAGTAAAGATACTCTGGTGAACAACTTGGAGGAGCTGAGGAAGATGGCCGAAGCTGTCTCCTCGCAGTTGGacgcCGAACGTAAAGAAGCTCAAATAAAGGAAGAACAAGAAAAACAAGCGAAAGAGATCAAACAAGAACAAAGCGATACAGACACAGCCAACACTATCCTCTACACGAGAATGCTCGAAGGGAAATGGTTTTCAATCCTACGGCACGAAGGCTCATTTTTGAACAACATCAACGAGGTGACTAGTGATGTGCCAATGTTCTGTGATAATGAACACACGTGCGAGCAAGTAGTGCTGTGCCAGGGACATAAGTGGGATGTTTCTAACAATCTGCATCTGTTGAACGATCCCAGTTTGTTCACGCTGAACAGTATGGTCACTAGTGTTCAGGTGCCGTCCAATAATGTGTATGCTGACTCGTGCTTGACGATGTCTGGCTTGGACCAGGACTTGATGGACGCTGCTCTGAAGAAGGGCGGGGAAGAGAATATAGAAAAGGAGACTAAAGAGCAGGACAACGATCTAGAGAAAGAGCTGCAAGCAGACTCGCTCAAACAAGACTTAGCTGTACAAAAAGCTAAAGCACAGAGCTTAACCAGCTTAGGACTTCTTAACTTCAACGCGCTGTCAACTTACGTGACATGTGACAGCCCACCCCCTATACAGATGGGAGGAGATGAGATGGAGCAGTTGAGGAAATGCAAAGTACATGGACTGCCGGCCAAACAGGCCAACCAACATGTGCCTAGGGAACTCAGACATGGCTGGTGGCGGATAACGGACGCTGAGCAAGTGAAAGAGGTTATGGATGCTCTCCATCCGCGAGGAGTTCGCGAGAAAGAGCTGCAGAACGCACTGGTGCAGCATCTACCTACTGTCAATAACAAGTTGCACATAGACAAAGGCGATACGAGCTCGACAGAGCTGTCCATATCTCACCTCGACCGGGTCATATCTGCGAACGGCGGCTGGGCCAGCGCTGACGCTCCTGGCTCCTTCTCGGCCAGCGCTGCCAGGAGGATCGACCTTCAGCTGCTCAGCATGGTGGAAGCATTTGAAGAAAGGGTTGCTACAGCGTCCTTGCAAGTGAAGGGATGGCGACCTTCCCGCCTCCAAATGCCAGAAGACGCGACCGGCGCTGAGATAGTCGCCCGAAGTCGCCACAAGCTGGCGCAAGTCGAGGCCCACATCGAGAGGAGATACCTCAAACCACCTTTGGTACAAAGGTACGCtagCACAACGGAGGCTAATATTGGCGCGGCGTTGCAAGCTGAGCATGGGAACTCCTCAGCATCGTCTCCGCAGAACTCCGATACTCCTAACGAAGGGAAACCGGACACAAAGGGCGTGGCGCGAGGTCTGGCGAACTGGCGGGAAGGCGTTGCGCGGTGCAACACGTCGGCTCAGCTAGCCATGATGCTGCAGGCGTTAGAGGCGGGAGTGGCCTGGGACAAGAGCATTATGAAAGCTAACTGTCAGTTCTGCCTGAGCGGTGACAACGAAGACGAACTGCTTCTGTGTGATGGCTGTGATAAGGGATACCACACGTACTGCTTCAAGCCACAAATGGACAAGATACCTGAAGGGGACTGGTACTGCTGGGAGTGCGTGAACAAAGCAAGGGGCGAGCGTGTGTGCATAGTGTGCGGAGGGGCCGGCTCGGGGCGGACCATCCCATGCGCACTTTGCATGCGGGCCTACCACCAGGACTGTCACTACCCGCCGCTCACCAAGAATCCCCGCGGCAAATGGTACTGCAACCAATGCATATCGCGCGCTCCGCCCAAGAAACCGAGGAACACTAAGAAACGGGAGAGCAAGCACAAAGACAACGTGGACCTCGATACCAGTATGGTGCCCAGTCCCGCTCCATCGCACGCGTCTACGTCGACCACAGCCGAGGACTGCTCAGCCACTGCACTTCATACGCCGGAGAAAGCCGAGTGCGCTGATAAAGAGGAGCCTGTTGTATGCGCCGTGCCAGAGCCTGAGAACGGAACCAACACCAACCATCATCCAGTGGCTCAGCCGGAATTCACCGAGGACGGTCCCCCGCCAGAAAAGCGACGGGCGTTACAGTTCGTCGGCGGGAACGGGGCGATACCACATGAAGATACCGAACAGAACAATATACCTGATGAAAGAGATAGCGAGAATGTACCTCTAGTGTCTCGCATGAAGAAAGAGAAGAACACAGCTAAGAAGATAGCTAAAGAATTACAGTTTTGCAAGAACCTCCTTGGTGATATGGAGATGCACGAGCACGCTTGGCCGTTTCTCATTCCCGTCAACACGAAGCAGTTCCCGCAGTATAAGAAAGTCATCAAGTGCCCCATGGACCTGTCTACCATCAAACGGAAACTCAACGATAGCATATACAAATGCAAGGAAGAATTCGCGTCCGACGTCCGTCTTATATTCAGTAATTGTGAAGTTTTCAATGAGGACTATAGTCCAGTTGGACGGGCCGGTCACAATATGAGGCAATTCTTCGAAGAACGCTGGGCTAACATCTGA
Protein Sequence
MDKESGDGADSAGKAPDALSALDAAGLFNAYYGMGRDGSGAGGAAAQAQAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAATLFGFGSCYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARIQTAGLQGFPPMGDPYSTLSALSAAGMKHPQKQSKPASRNERSGRSSTSSSASTKEKSPSTSNANSQPNLSDWASTYGFPKTSSPSTMHSQSLSSLASLNSLVSSPHQSKSKQQPPSHSQSRKQSSSSTSTSSKSKERELALLRGDLMLAQAAAHGAYHAAVAHAAKGKNIQNMSSLYPFGMPGSDKDRHGGIDALTGLPHTILSAALEGGDPASVLGGVRLPPDTEIIKYTSALTGPKAPPGTTNRGRKKTISLDPPQVSVHPSASDGRGTPLPSKRQKLRNDEYGARSAVEVIRLPTKPERPASVAGTPPPNLADYAGISRELLQTIASQSGVSLAALERQLAGSNTGRSKDTGLNLSKSNASSEEAPLDLGLKNDDDAPLNLSLKPTPPASQASDALSRLTSLSSSLNASSHNDRTSRRKPGGRPRRVVPELNTSVADSPRPRSSGSEDSESVPAWPSREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAQQLLGEADLEKLKSVLGEAASTNSECSSDSCPSDSDVSEDRRDQDAQLRLPLALGWKRVTVIKGLSRNCNIKGDVTYAPPEPHSSFKITNAQDLQTFLESNPCPPLCTDNFSFNGRHVVGDFVQPPMDSGEPLVFNETEITKRLEEARALAALTGPRPTPPPVDRRIELARRQQAARDARRDASNRSRDQARLVRELERSEKAEIVKREKEVRSQQLLEHINKNRTQLTIEALPMPKEQKTEIKTERKERKMPPISLSLIPVSGPKDNSPIKMNFDNDIEEYNALDKMKDFAEKAAFDTPKRKDKYDFTIKEGNNMDKLIESYSRISEFVNGCDWSKSPEKDPKKLERDPKLEKKYLEAKNEFMSQNLMLMPKSNAEKCQLKKGTDVIDLSDNEDNDITDIIRKKLQKGCLNIGKDGALSISVQQCTEIGPAKRKKQEDLDKQKFEEQIKRQQEREIKRQQAMILKEQQKYINEERERRRQHTSFIRQLDSRRRWEDRERRKHQNLLDRLLVKEKKLQERRKEMELLSELRRPQEDSTLSDQKPLPTLNRIPGLKLPGQATADILQVYEFIHNFGQTLGFDMDSMPTLNTLQMALLPDCCADAEEELIQVLTQLLITAIEDPGIPHPGRHTTLLGHAIRMGDITPANLSEVLRIYLYANATGEIKALTGLTAERERDRRVADHHQNDAEMLSSSTNSKNQAYYEHLLNNQTYKLSVALRDKPFLALNPTMKAAILAFLCNELLQNKSVLRQIDGSLEHLNQLKKERYLMDMKIRKVRVLHQRKVRAEQTEKQQALALERMQKLVEESTANLSRASPHPTDDEHQSEKSETPKKDEHEDESPFKDPNNDESDKEMSPMKDLKDLATKELSSIKELSSRRLNNNKEECSPSEHKIDKDSVMGDEMPSDLESEGTQPEEDEDKNLSSEELSRKLEKLLRQSEQQQQQLIAGSHALRATCYGQDRYWRRYWSFGKCGGIFVEGMESAQPEILDYHEALEAAASQKPPEVKKKRGKTEKKDLDEEKNPETEAQKKEEALKTELELKNIKSELNLSDHTQIIKYEPNQGGCKLEGSSIKMEEKYIQQQQNSQQDMLDIEDSIPTAFLVQKPSHKPMYAQQAEPVDKPQEIVKVENVVKTEEKEEESKDTLVNNLEELRKMAEAVSSQLDAERKEAQIKEEQEKQAKEIKQEQSDTDTANTILYTRMLEGKWFSILRHEGSFLNNINEVTSDVPMFCDNEHTCEQVVLCQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPSNNVYADSCLTMSGLDQDLMDAALKKGGEENIEKETKEQDNDLEKELQADSLKQDLAVQKAKAQSLTSLGLLNFNALSTYVTCDSPPPIQMGGDEMEQLRKCKVHGLPAKQANQHVPRELRHGWWRITDAEQVKEVMDALHPRGVREKELQNALVQHLPTVNNKLHIDKGDTSSTELSISHLDRVISANGGWASADAPGSFSASAARRIDLQLLSMVEAFEERVATASLQVKGWRPSRLQMPEDATGAEIVARSRHKLAQVEAHIERRYLKPPLVQRYASTTEANIGAALQAEHGNSSASSPQNSDTPNEGKPDTKGVARGLANWREGVARCNTSAQLAMMLQALEAGVAWDKSIMKANCQFCLSGDNEDELLLCDGCDKGYHTYCFKPQMDKIPEGDWYCWECVNKARGERVCIVCGGAGSGRTIPCALCMRAYHQDCHYPPLTKNPRGKWYCNQCISRAPPKKPRNTKKRESKHKDNVDLDTSMVPSPAPSHASTSTTAEDCSATALHTPEKAECADKEEPVVCAVPEPENGTNTNHHPVAQPEFTEDGPPPEKRRALQFVGGNGAIPHEDTEQNNIPDERDSENVPLVSRMKKEKNTAKKIAKELQFCKNLLGDMEMHEHAWPFLIPVNTKQFPQYKKVIKCPMDLSTIKRKLNDSIYKCKEEFASDVRLIFSNCEVFNEDYSPVGRAGHNMRQFFEERWANI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00705034; iTF_00699191; iTF_00706038; iTF_00697368; iTF_00696494; iTF_00698339; iTF_00702925; iTF_00700145; iTF_00701088; iTF_00702009; iTF_01170622; iTF_00686367;
90% Identity
-
80% Identity
-