Hpse014477.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Hofmannophila pseudospretella
Gene Symbol
egg
Assembly
GCA_947369225.1
Location
OX376338.1:3219681-3264274[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.43 1.5e+03 -0.7 0.1 10 38 1871 1917 1866 1919 0.78
2 2 1.3e-12 4.4e-09 36.2 0.0 4 75 1949 2013 1946 2015 0.88

Sequence Information

Coding Sequence
ATGAGTTCTTCAGATAATCAGGACGAGCCTCCAAGTTCGAGTAAAGTAGATATAGTCCACGTGTCTACGTGTTCTGTCCCAGATCAAGTCACTACAAAAGATCCAATAATGCCACAAAAGGCACCTCCAGAAATGATTACAACTATTCACACCAAAGGTGGCGGTGACTGCAAATCACCATCACATCCACCTTTTACTGACAAAGATAACCCCAAAACAGATTCCACTGAGGTTATTATTCATAATATTGAGGACAAAGATAAGCAAGATCTATCTACAGACAAAGATGACCCCAAAATGCATTTGACAGAAGTTACTGATCTTATAAAGAACAAAGACAAAGATGAGCAAATCAGTGAAAATATTACAAAAGTTGGACTAACCACTGTTGATAGTGAAAATCCAGGCCCGAGCAAATATATTACCAGTAAAGCCGTCATTGTAGACAATATAGAATTCTCTAGTGATAAATCAGACACATCTAGTATAAATATTGATCGAGAAGACATAAAAGTAGATAATAATTTGAAAACACTAACTCAGAGACTTCTGGATACTAGATCAAATGCTAGCAGTCCTAGAACACCTGGAGATGTGGATGAATACAGTAGTGAAATGCAAGAGGAGGAAATGGTGTTAAAATGGGATGACACTGATGAGTCTGATGAAATTAATGTCAATGATGATGCTAAGAAACATTCTGACTCTTTAAAAGATAATAATGATGAGTCCAATCTTGACAAAGCTGGTAATATTGATAAAAAATATAGTACTGGTACAGAATTGATTGAAAAAGATATATTGAAAGCGATTGATGCACAAATATCTAAGTTAAATGCAGAAGTTCCTACTCAGGATAAAGATAGGAGAAATGTGGAACAACATTCATTGAATTCTAGTAAAGATGGAACTATACTGAAAGTAATAGATGTACAAGTATCTGGGTTAGATGCAGAACTTCCTAGTTCTACTGATAAACATAAGGATAATGTTGAAGAACAATCATTGAATATTAAAAAAGATGAATCTATTCTGAAAGTAATTGATGCACAAATAACTGAATTAAATTCAGAGCTTTCTAGTTCTACTGTTAAAGAACATTCAAAAAAGTCAGAAAATACAACATCTACAGTTCTAGTAGACAAGAATGAAAAGGAAACAGATCTTTCTGAAGCAACTGACACAAAAAATGTGATAGTTAATAATCCAATTAATGATGGTGATAAATATCCGAAGAAAGTAAATGTAGGAACTATTGGATATGCTGCATCAACATTTAATACTGATGTTTTTGATGAAAATGAAGACAGCACTAAAATGGATGTAGATACTAACTTAGCAGTTGATAGTATTATTGCTGATCTTGATCAAATGATTGATGAACCAACCAGTACTGAAGATAAACCAATAAACACTTCCAAATTAATTCAAGAAAATATTTCAACTGCAACGGATAATGATAAAATCGCTAAAGATGTTAACATTATTGATACAATTAAACCAATTGGTCTAACACAAATCAATCCAAATGATAATCACATGGATTTGGATTCCTCTCATAAATGTGAAGAAACTGACATTAAAGTATCAGAACTCAAACCACAAAAGGTTTCTAATACTGCTGATAAAATGGATTTAGACTCTTCTGTGGTACTAGATGATAGTCTTACTAATAATGAACCAATCAGTGACATACAAATTACAGCAAACAGTACTGCTATAGACCCAGGAACATATGACATGAGTTTTGAAGATACTAGCACTGCAAAACCTGATGTACCTAAGGACAGAGAACTAAATTTCACAGCTAGTCAGCAGTCTTTATCATCGGAACATGACTATAATAGTACTATGATCGGGCCTACAGACCACAATTTAAAGAAACCTGATATGATGATAGAGATTCCAACTCAAGAATTGATTGATTGCACAGATGATTCATTATATCTATCAAACAATGATTCAACCACTGATATAATAGACCAGAAAAATATTGTGGCTGAAGACAAGGTCACCAAACAACAAACTGATGCAGAAAAAGCACAGGAAATTACAGAACCTCCTAAAAGTCTCACAAAAATTGACACCAAAGCTTTAAAACTGCCTGATATAGATGTTGAAAGTAATAAACAAAAAACAGTGGACAAATCAAATGATTTGCCTGTTAAAGATTCTGAAAAAAGCAAAGAAGAAGCTAAATCGGATATTGAAGATACTGAAGTTAAATCTTGCAAACAGATTGAACTACAACTTTCTGTAGACAATATTGTGACTCCCAGCATCAAAGACCAATCTGCCATTGAAGCTAATAAACATAAAGATATTTCTATTGAACAGATTTCTAAAGCTGATGACTTATCATCCAAAGAGGAAGGTAATCTCCCAATTTCAGAACAACCATCTGCAAGTGAAGATCAGTCATCTATCAAAAAAATCTCTTCAAAAGATGAACAAAAATCTAAAAATGAAGATCAATCTTCTATGAAAGAACTTCCTGAAGACGCTGCCACAGTTTCAACAGAAGAAAGAGCCAGTAAAACTGCTGACCAGTCATCTGTGATGGAAAATGAACAGTCAATGAGAGCAGACACATCGGATGAGGTGCCAGAAGTGACAGACAGTCTTGGGCTGTTGGCAGAGTCTTCCAGGGTGATGGAGGATGATGAGGAACAGGAGACTTCTGAGCATGACGATGACGATGGTGACGGAGAAGAGGACTTCGACCCTGATGATGAAAGCAGCAATCAAATGACAGCAGAGCACTCTGAAGACTCGAACGCGCAGCAATCCGAGACGGACCTATCCAAGGACAAGGCTCCGGCCGTAGAAGATTTACACATTGAAACGGATGATGCACAAGACTTCATTGATAACACGCCGGAGGTTGGCACTCCTGAAGAAGAGAAAGAAGAATTTAACTTCGCTATCAGCAATGTTATCAGTGAGACATTGGTAGAGGATAAGGAGGGAGATGAGTCTATGGAGGTGGTGGTTGAAGATATCGTTTCTGATGATGTGGAAGTAACATCTGATACTATTGGAGATCACCAAATAGATGGCACAGAGCAACTAGAACCAGCAGTTGAGACAGAAGACACCACTGTTACAGAATCAACTATTGAGAGTGAGAAGGAGAAACCAGAGGAACCCGTTCAAGTCACAGAAACACCAATGGACATAGAGACGGTCAAACTGTCAGACACTTCTGACAATGACGAGCCAGGAGACAAGGTCAAGGACGAAGGCCAGCTACGGGAGCTACTGTCTCCGACGCCAAAAAAAACAGACAACACTGCCGACAAAAGCAAGCAGTCGCCGAGCAAGGCCAAGAAGTTGGAGATAACCAAACCGAAGCACGTTGTCAATATAGTTGAGCTGGAAGAGAGCTCCTCGGAAGATGATATACAAGAAGTCTCGAAGAACGACGTTGCAACGACTCCGGATATAAAATCGGATGGTGTTACAAGCGTCAATATATCCGGACAGATAGAGATCATGTCATCCGGCGGGAACACATCGGATATTACGACGAAGGAGGGGGAGATCGTTATAAGCGGAGTGCCGAAACCACCTCCGCAGAAACCTGCACGGTTAAATACAAGCGAAGTGACCATTAAAACTGCAAGTACCACAGAATCTACCTTAGTTATTCCTGAAGCGAAGATTACCGAGCCAAAACGGGAACCCAGTATGAGTATGGAAGTGTTCAGTTTGGATTCCGACGATGAAGATAGCCAGCCAGCTGCTGAAAAGCCAGCAGAAGCGGCCAAGCCTTCAAACAACAAGTGTATTAACAACCTATGCACTAGCGATGGTTCTACAACATACTATATTGCAAATCCGTCAGTCGTGGCGTATTTCGAACCGGGGCGGAAGAGGAGAGCGCTGGTCTGCCAGGGTTGTGCTGACGCCGTCAATAGAAGGGCTCAGACCCTAGTGGAAGGCGTCAAGAACTTCACTCCTCTACTCGACATGGACATGGGTCGGCCGTGCCAGGAGCTGGTGGAAATATCCGACTCCGATTCCGACGACGAGGGTGGGACTATTGAAGTGGAGAAGGAGATCCTTGGCAAGGAGGGGGCGAAGATGCTAGAAGAGCAACTAGCAAGCGTCCTAAACGAGACGTGGTTAAAATACAATCTGGATACACGCTTCCGAGAAACTCAGGACGAGCTACAAGCGGAACTGGAGCGATTGCAGAAGGACAGCACAGAAGTGGACATAATGCTCACGGAATGCCAACAAGCGACGGACCGACTGCGCGCGGAGCTGTACGATACTTTCGAGCGAGAGAGACAAACTGTACCTGCCATCGTCATATTCGATACGCCGGAGAACATGTTCTCTTGCACAGAAGCCGCTCAACTAGCCACCATGGACGAGAAAAGGCAGTCAAAGCGGCGGTTGTCATCTGCGAGTGAGACGTCGGCGAAACGACCCGCCATACCTCTCGGGTACACACCTTTAGACAACGATCCAGTCAAGACTCAAACTCCGGTAGCGGAGCCGGCTAAACTGGAGGATGTCAAACCTCCAGTCCCCATGGTGCCAGCTACTGTGACTGATGCGTCGAAACTTGATGATGACAAAGACATATCAGTAGTGAATCTCTCCGCTGAATCCGCCCCGGCTGACCTACCCGCCCCAGGGGAGATCACCCGCCCTTCCCTCAGAGTCAACATGCAAGTGTTCGCCATGAAGAACGCCTTCGGGTCTTGGTTGAGAGCTAAGGTCGTGGAGTGTACTCCTAAGGGCTCCTCGCCAGCAGCAGCGCACTTCACGTTATGTCGAGTCAAATTTGAGAACAAGCTGGCGAAGAATGCGTACAAGCTGTTGCCCGGACGCTGTCTGGCCTACCCCGAGCCGGCTGAAGTGAGGATGACCATCGGCACCCGCGTCATCGCCCTGTTTAAGGACCACATACTGACATCGCGGCGGGAATCTTACTATTCCGGCATCGTGGCTGAGGTGCCTAACCCCGTCAACAACTACAGATACCTAGTATTCTTCGACGACGGCTACGCTCAATACGTGCAACACAGAGATACGCGTCTTGTTTGCGAGTTCTCCTCGCTAGTGTGGGAGGAAGTGCACCCATTCTCCCGGGAGTTCGTCCGGGAATACCTGCTGGCGTACCCGGAGAGACCCATGGTCCGACTGCATACGGGGCAGAGTATCAAGACCGAGTGGAATGGTAAATGGTGGATATCGCGGGTCATCCAAGTGGACGCGTCTCTCGTGCTTGTCCACTTCCAGGAGGACAACCGTACAGAGTGGATATACCGCGGCTCCACGCGTCTGGCGCCATTGTACCTCGAGTTACAGGCGGCGGAGAGGCACCGCGCCAGGCCTCTGCCCAGAAACAGGGTGCAGAGTAAGTGGATATACCGCGGCTCCTCGCGTCTGGCGCCATTGTACCTAGAGTTACAGGCGGCGGAGAGGCACCGCACCAGGCCTCTTCCCAGAAACAGGGTGCAGAGTAAGCTCAACATGCCGTACGTGGAGTACACGCGGTCGGACGAGCCTCCCCCACCACCGCCGGCCGCGCCCCCCACCACCAACTCAACCACCACCAAGCTCACCACGTACGGGCAGCTGCAAACGCACGCGCAGGCACAGGAGGACTTCCGGCGCCAACGCGCCGTCGCCAAGAAGTCTACCGGCGCGCCCCCGCCGACCCCACCGCCGCCGCAGCCGCCGCCGACCTCTGTCGCCGACACTGTCACCAGCAGGGTGGTGTACTACACGCCCAAGAATGCAGTCAAACCTCACAAAATGGTCACGCACACGTGCTCCCCCCGATGCAGGCGGAGCGACGTTCTGGCCCTACAGGATCTGCGCACCTACAACCCGTTAGCTAAACCACTGCTCAGTGGCTGGGAGAGACAACTGGTCCGTTTCAAGGGCCACAAGCAAGTGATGTACCGGGCGCCGTGCGGCCGGCGCCTGCGCAACATGCGGGAACTACACCGGTACCTTCGCACCATACAATCGGATATGGGGGTTGACCTGTTCGATTTCGGGCCCGGCACGCATTGTTTAGCGGAGTTCGTGCTGAACAAATGCATTATTGCTAAGAAGGACTTGTCGAACGGCAAAGAGAACGTGCCAGTGCCCTGCGTCAACTACTATGATAACTCGCTGCCGGAGTTCTGCTCGTACAACACGGAGCGGACCCCCACGGAGGGGGTCCCACTGAACCTGGACCCCGACTTCTTGTGCGGCTGCGACTGTACCGACGACTGTGAGGACAAGTCAAAGTGCGCTTGCTGGCAACTGACGCTGGAGGGCGCCCGCACCATCGGACTAGAGGGGGGCAACATCGGATACTCGTACAAGAGGCTGCCAGAGCCTCTATCGTCCGGAATATACGAGTGCAACTCCAAAGGGGGCAACATCGGTTATTCATACAAGCGGCTGCCCGAGCCTCTATCGTCCGGAATATACGAGTGCAACTCAAAGTGTAAATGCAAGAGCACGTGCCTGAATCGCGTCGCGCAGCATCCCTTGCAACTGAAACTACAAGTGTTCAAAACCCTAAACCGCGGGTGGGGCATCCGTGCCCTCAACGACGTGCCCAAAGGGTCTTTCCTCTGCGTGTACGCTGGGAATCTGCTCACTGACGCCACCGCCAATCTGGACGGCCTGAACGAAGGCGACGAATATCTAGCCGAGTTGGACTACATCGAAGTGGTGGAGCAGATGAAGGAAGGTTATGAAGAGGACATTCCTGACGCAGACAAGAAACTAGATAAGAAGGAAACCGGCAAGGGGTCAACCTCTTCTGAAGAGATGTCGTCCTCGGAAGACGAGGACAACTCCAAGAACGAGAAGGAAGACGGCGACTTCGAACCCGGACACGTGTACGGGATCACTGAGTTCAACAAGCGTCTTCGTCGTCGGGAAAAGGCGAAGAAAGAGAGGGCTAATGCGGCCGCCGCCGAGAGGCATAGGAGTGGGCAGGACAACTGCATCACGATAAGTGACGACGAGGAAGTGAGGGAACCGTCGAGGTTCATGGCACAAGCTGGGATGGGTGCCAACGAGTTTATATCTAAGTACAGGTCGGTGAGATCGTGTttcggcgaagatgaggcttgctatatcatggacgctaaggttcaaggcaacatcggacgatatcttaaccattcgtgctcccccaatgtgttcgtacaaaatgtattcgtcgacacacacgacccccgtttcccttgggtggcgttcttcgcgctatggcccattcgcgccggcacggaactgacgtggaactacaactacgacataggttccgtaccctcgaaggttctttattgctactgcggggctccaaactgtaggggacgattgttgtaa
Protein Sequence
MSSSDNQDEPPSSSKVDIVHVSTCSVPDQVTTKDPIMPQKAPPEMITTIHTKGGGDCKSPSHPPFTDKDNPKTDSTEVIIHNIEDKDKQDLSTDKDDPKMHLTEVTDLIKNKDKDEQISENITKVGLTTVDSENPGPSKYITSKAVIVDNIEFSSDKSDTSSINIDREDIKVDNNLKTLTQRLLDTRSNASSPRTPGDVDEYSSEMQEEEMVLKWDDTDESDEINVNDDAKKHSDSLKDNNDESNLDKAGNIDKKYSTGTELIEKDILKAIDAQISKLNAEVPTQDKDRRNVEQHSLNSSKDGTILKVIDVQVSGLDAELPSSTDKHKDNVEEQSLNIKKDESILKVIDAQITELNSELSSSTVKEHSKKSENTTSTVLVDKNEKETDLSEATDTKNVIVNNPINDGDKYPKKVNVGTIGYAASTFNTDVFDENEDSTKMDVDTNLAVDSIIADLDQMIDEPTSTEDKPINTSKLIQENISTATDNDKIAKDVNIIDTIKPIGLTQINPNDNHMDLDSSHKCEETDIKVSELKPQKVSNTADKMDLDSSVVLDDSLTNNEPISDIQITANSTAIDPGTYDMSFEDTSTAKPDVPKDRELNFTASQQSLSSEHDYNSTMIGPTDHNLKKPDMMIEIPTQELIDCTDDSLYLSNNDSTTDIIDQKNIVAEDKVTKQQTDAEKAQEITEPPKSLTKIDTKALKLPDIDVESNKQKTVDKSNDLPVKDSEKSKEEAKSDIEDTEVKSCKQIELQLSVDNIVTPSIKDQSAIEANKHKDISIEQISKADDLSSKEEGNLPISEQPSASEDQSSIKKISSKDEQKSKNEDQSSMKELPEDAATVSTEERASKTADQSSVMENEQSMRADTSDEVPEVTDSLGLLAESSRVMEDDEEQETSEHDDDDGDGEEDFDPDDESSNQMTAEHSEDSNAQQSETDLSKDKAPAVEDLHIETDDAQDFIDNTPEVGTPEEEKEEFNFAISNVISETLVEDKEGDESMEVVVEDIVSDDVEVTSDTIGDHQIDGTEQLEPAVETEDTTVTESTIESEKEKPEEPVQVTETPMDIETVKLSDTSDNDEPGDKVKDEGQLRELLSPTPKKTDNTADKSKQSPSKAKKLEITKPKHVVNIVELEESSSEDDIQEVSKNDVATTPDIKSDGVTSVNISGQIEIMSSGGNTSDITTKEGEIVISGVPKPPPQKPARLNTSEVTIKTASTTESTLVIPEAKITEPKREPSMSMEVFSLDSDDEDSQPAAEKPAEAAKPSNNKCINNLCTSDGSTTYYIANPSVVAYFEPGRKRRALVCQGCADAVNRRAQTLVEGVKNFTPLLDMDMGRPCQELVEISDSDSDDEGGTIEVEKEILGKEGAKMLEEQLASVLNETWLKYNLDTRFRETQDELQAELERLQKDSTEVDIMLTECQQATDRLRAELYDTFERERQTVPAIVIFDTPENMFSCTEAAQLATMDEKRQSKRRLSSASETSAKRPAIPLGYTPLDNDPVKTQTPVAEPAKLEDVKPPVPMVPATVTDASKLDDDKDISVVNLSAESAPADLPAPGEITRPSLRVNMQVFAMKNAFGSWLRAKVVECTPKGSSPAAAHFTLCRVKFENKLAKNAYKLLPGRCLAYPEPAEVRMTIGTRVIALFKDHILTSRRESYYSGIVAEVPNPVNNYRYLVFFDDGYAQYVQHRDTRLVCEFSSLVWEEVHPFSREFVREYLLAYPERPMVRLHTGQSIKTEWNGKWWISRVIQVDASLVLVHFQEDNRTEWIYRGSTRLAPLYLELQAAERHRARPLPRNRVQSKWIYRGSSRLAPLYLELQAAERHRTRPLPRNRVQSKLNMPYVEYTRSDEPPPPPPAAPPTTNSTTTKLTTYGQLQTHAQAQEDFRRQRAVAKKSTGAPPPTPPPPQPPPTSVADTVTSRVVYYTPKNAVKPHKMVTHTCSPRCRRSDVLALQDLRTYNPLAKPLLSGWERQLVRFKGHKQVMYRAPCGRRLRNMRELHRYLRTIQSDMGVDLFDFGPGTHCLAEFVLNKCIIAKKDLSNGKENVPVPCVNYYDNSLPEFCSYNTERTPTEGVPLNLDPDFLCGCDCTDDCEDKSKCACWQLTLEGARTIGLEGGNIGYSYKRLPEPLSSGIYECNSKGGNIGYSYKRLPEPLSSGIYECNSKCKCKSTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPDADKKLDKKETGKGSTSSEEMSSSEDEDNSKNEKEDGDFEPGHVYGITEFNKRLRRREKAKKERANAAAAERHRSGQDNCITISDDEEVREPSRFMAQAGMGANEFISKYRSVRSCFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALWPIRAGTELTWNYNYDIGSVPSKVLYCYCGAPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-