Hpse020758.1
Basic Information
- Gene Symbol
- Bgb
- Assembly
- GCA_947369225.1
- Location
- OX376312.1:7488970-7496112[+]
Transcription Factor Domain
- TF Family
- CBF
- Domain
- CBF_beta domain
- PFAM
- PF02312
- TF Group
- Beta-Scaffold Factors
- Description
- Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.1e-78 2.5e-74 248.8 0.5 1 164 33 189 33 192 0.97
Sequence Information
- Coding Sequence
- ATGCACGCCATGAGTGATCCGGCTGCCCTGGCTGGCATGCTGCCCTTCGACTCCATCGGGCTGTATGAGCAGCCGAAACCACGGTTCATCTTCAAGATGCCACGAGTAGTTCCGGATCAAAAAGGAAAATTTGAATCCGATGACCTTTTCAAAAGACTCAGTCGAGAAAGTGAGGTGAGGTACACAGGCTACAGAGACAGGCCGCCGGAGGAGCGCCAAATGCGCTTCACGAGCGGCTGCCGCGAGGGCCACACCGAAATAGTGTTCACAGCCACAGGAACCAACCTGCATCTGGGCTTCGACCACTCACCCTACAACAATCGCGGCTGTGACTTCCAGAAGGAAAGCGGCAAGGTACACATAGTATCGCGATTCATAATGAACGGTGTGTGTGTGCGATGGCGCGGTTGGATTGACCTGGAGCGCCTGGATGGAACCGGCTGCTTAGAGCTGGATGAAGAGCTAGCTGCAATCGAAGACGCAGCCCTGCGCGAGCAGATTGAGCGGTACAACCAGCGGATGCGGGACTTCGAGAACAAGCAGCGCGCGTACCGCGAGCACGGCGAGGAGCTGCGCGCGCACTCGCACGTGCACGCACAGCGCTGCCACCAGCCGCGCCAGCCCCCGCACGCCGCGCACCCCTCCCACCCGCACCCTCCGCACCCCGTCCACATCAAACCGCATTCGCAAGGCGCTCTCATCTCGTAA
- Protein Sequence
- MHAMSDPAALAGMLPFDSIGLYEQPKPRFIFKMPRVVPDQKGKFESDDLFKRLSRESEVRYTGYRDRPPEERQMRFTSGCREGHTEIVFTATGTNLHLGFDHSPYNNRGCDFQKESGKVHIVSRFIMNGVCVRWRGWIDLERLDGTGCLELDEELAAIEDAALREQIERYNQRMRDFENKQRAYREHGEELRAHSHVHAQRCHQPRQPPHAAHPSHPHPPHPVHIKPHSQGALIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00837229;
- 90% Identity
- iTF_00761386;
- 80% Identity
- -