Basic Information

Insect: Hirtodrosophila trivittata
Gene Symbol: ftz-f1_1
Assembly: GCA_035045065.1
Location: JAWNNK010000816.1:7728233-7743195[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 2 2.2e+04 -7.1 24.3 30 129 61 155 42 167 0.56

2 2 1.4e-87 1.5e-83 281.8 7.9 1 408 323 773 323 775 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	2	2.2e+04	-7.1	24.3	30	129	61	155	42	167	0.56
2	2	1.4e-87	1.5e-83	281.8	7.9	1	408	323	773	323	775	0.80

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAgcttgagcagcagcagccagcgaGTCCGgcgcacagcaacaacaacaacaacaacaatggaagtagcaacaacaacaacaacaacgccgaTAACGATACAAATGCATTGAGCAATTCCGATAACGATTACAGCGCCTACACGCTGCAGCTGAGCaatcatcaacagcaacaacaaccacatcaACACAcgcatcaccagcagcagcaacagcagcagcaacaacagcagcagcagcaacaacaacaacaacaacattaccaacagcaacaacaacaacagaatattgccaacaacaatgcgaATGCATCGAATCAATTCAATGCCTCCTCctattcgtatatatacaatttcgATTCACAGTATATATTCCCGACAGGCTATCAGGAAACCAACTCATCCCATTCGCAGCAGAGCGGCAATGGTGGTGGCAACTCTGGCCAGCTATTGAACGGCGGCGGCAGCTCGGCTGGCAACGGTTACATGCTGCTGCCACCAACAGCCGGTGGCGCCACAtcagcagccgccgccgccgccgctcaCATGTCCGGCAATGTGGGTGGCAACACGGGCGGAGGCAACGGTACGGGCACAGCTACCGCCTCCGGCGGCCATCATGGCGGCACCAGTGCCACCTCCGCCGGTGGCGAAGCCATCGATTTCAAGCATCTCTTCGAGGAGCTCTGCCCCGTCTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTCCTCACCTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACCGTTCAGAACAAAAAGGTCTACACTTGCGTCGCGGAGCGCTCCTGTCACATCGATAAGACCCAGCGCAAACGTTGTCCATACTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAGCTAGAGGCGGTGCGAGCGGATCGCATGCGAGGCGGTCGGAACAAGTTCGGACCCATGTATAAACGGGATCGGGCGCGGAAGCTGCAGGTCATGCGGCAGCGTCAACTGGCGCTGCAGGCGCTGCGCAGTTCGATGGGAACGGACATCAAACCGACGCCCCTCTCGCCGGGTTATCAGCAAGCATAtccaaatatgaatattaagcaagaaatacaaatacctCAGGTATCCTCACTCACACAATCGCCGGACTCATCGCCGAGCCCGATTGCCATTGCCTTGGGTCAGGTGAATGCCAGCGGGGGCGGTGTGATAGCCACGCCCATGAATGCCGGCAGTATCGGCggcggcaatggcaacggcagctCCTCACtgggcaacggcaacaacaacaacagcaacaacaacagcagcagcagcacaggcagcagcagcggaggCGGTGGAGGTGGCAACAACGCtggcggcggcaacaacaacggcaacaacaatggcgcCGACGGCCTGCAACGCAACGGAAACGGCCCcaacgccaacagcaacacggGCTGCCACGAAGCCGGAACTGGATCTCTGCAGAGCACAGCCGAATCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAACCGCTGAGGGTCTCACCGATGATACGTGAGTTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTCTTTGCGCTGCTGCAGAAGCAGACGTACAACCAGGTTGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTCGATCAGAATCTGTTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTGAAGGTGGACGATCAGAtgaagctgctgcagcacTCATGGTCCGATATGCTGGTACTGGACCATCTGCATCATCGCATCCACAATGGTCTGCCGGATGAGACGCAGCTGAACAATGGGCAGGTCTTCAACCTGATGAGCCTGGGCCTGTTGGGTGTGCCCCAGCTGGGCGATTACTTCAATGAGCTGCAGAACAAACTGCAGGATCTGAAATTCGACATGGGCGACTATGTCTGCATGAAATTCCTAATATTGCTTAATCCAGATGTGCGCGGCATTGTCAACAAGAAGACCGTCTTGGAGGGTCACGAGAATGTCCAGGCAGCGCTGCTGGACTACACGCTGACGTGTTATCCCTCAGTTAATGATAAATTCAGGAGGCTATTGAACATACTACCGGAAATCCACGCCATGGCCGCACGAGGCGAGGAGCATCTGTATTCAAAGCACTGTGCAGGCAGTGCGCCAACGCAGACGCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTaa
Protein Sequence: MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNNNNNNNGSSNNNNNNADNDTNALSNSDNDYSAYTLQLSNHQQQQQPHQHTHHQQQQQQQQQQQQQQQQQQQHYQQQQQQQNIANNNANASNQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGGGNSGQLLNGGGSSAGNGYMLLPPTAGGATSAAAAAAAHMSGNVGGNTGGGNGTGTATASGGHHGGTSATSAGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPMNAGSIGGGNGNGSSSLGNGNNNNSNNNSSSSTGSSSGGGGGGNNAGGGNNNGNNNGADGLQRNGNGPNANSNTGCHEAGTGSLQSTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00485910;
90% Identity: iTF_01556155; iTF_01570270; iTF_01570286;
80% Identity: -