Htri005358.1
Basic Information
- Insect
- Hirtodrosophila trivittata
- Gene Symbol
- sba
- Assembly
- GCA_035045065.1
- Location
- JAWNNK010000658.1:10375063-10385900[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 4.9e-09 1.5e-05 24.8 0.1 10 58 236 275 229 298 0.82
Sequence Information
- Coding Sequence
- ATGGCTGCCACATCCGCTGgccaacagctgcaacagcagcagcagcagcaacagcagcatcaacataaattgaatattgttgGCAATGCGGAGACTGTTGCTGGCGTGTTGCAGGTCAAtgagttgcagcagcaacagcaacaacagcttaATATGTAtaagcaacagcatcagcaaatgttgcatcaacagcagcaacagcaattctatcagcagcagcaacaaacgaaATTTGTATCGCGGGTCGTTACAAATGCCGCAATGcaaccgcaacagcagcagcagcaacaacaacaacaaatcttaCCAGCTGGTTTGGTAAATGGTAACGCCAACATGATGCAAGCGACAAATGTTGCcgCTATCAGTCCgcagctacaacagcaacaacaacagcaaagcaaacatCGACAGGCGCAAATAAAGTTGCCTGTCAAATCAGtagcagtggcaacagcagtagcagcatcagcaacagttgctgctacGCATTGCATGCCAGCAACAATTGCATCGCGTCACCTCAGTCAAAACAATCAACATCAGCTCTATGCAAAGAATGTAGCCAAAACCAACAATGCCAACAGTAATgctatcaacaacaacaacaacaacaataataacaacaacaacaataacaatattaacaacaacagcaacaacaacaacaccaacagcagcagttacaacagcaacagcaacgcaaATTTAGCTCCAGGCTGGCGTCGACtaaccaacaacaatgaagTGGCCTACATCAGTCCCACGGGTAAAACATTGCGCACACAATATCAAATCAAGGACTATTTATTAACACAGGGTACCTGCAAGTGCGGCCTGCCGTGTCCACTGCGGCCGGAATACTTTTTCGATTTTAATGCTCAGTGCCTCAACAGCTCAGTTGGTCGCATTATGTGCGTGAAGGCTGCCCCACATCGTCTGGCAGCTCCACAAGACATGATATGTCAGGGCCAACAAGGCAACTGTGTCCGGTCTCTGTCCGGCTATCCATCCAACATGACCCGAAACTGA
- Protein Sequence
- MAATSAGQQLQQQQQQQQQHQHKLNIVGNAETVAGVLQVNELQQQQQQQLNMYKQQHQQMLHQQQQQQFYQQQQQTKFVSRVVTNAAMQPQQQQQQQQQQILPAGLVNGNANMMQATNVAAISPQLQQQQQQQSKHRQAQIKLPVKSVAVATAVAASATVAATHCMPATIASRHLSQNNQHQLYAKNVAKTNNANSNAINNNNNNNNNNNNNNNINNNSNNNNTNSSSYNSNSNANLAPGWRRLTNNNEVAYISPTGKTLRTQYQIKDYLLTQGTCKCGLPCPLRPEYFFDFNAQCLNSSVGRIMCVKAAPHRLAAPQDMICQGQQGNCVRSLSGYPSNMTRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -