Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: -
Assembly: GCA_037075165.1
Location: JBAMCL010000572.1:401198-405237[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00049 0.033 14.9 0.6 1 23 205 228 205 228 0.97

2 12 6e-05 0.004 17.8 2.7 1 23 233 256 233 256 0.95

3 12 0.00025 0.016 15.8 4.8 1 23 261 283 261 283 0.98

4 12 8.2 5.5e+02 1.6 5.6 2 23 290 313 289 313 0.89

5 12 0.00056 0.037 14.7 1.0 3 23 323 344 322 344 0.95

6 12 0.0027 0.18 12.6 0.1 1 23 350 373 350 373 0.95

7 12 0.082 5.5 7.9 0.2 5 23 389 408 384 408 0.90

8 12 3.5e-05 0.0023 18.5 0.4 1 23 437 459 437 459 0.98

9 12 1.7e-05 0.0011 19.5 5.3 1 23 465 487 465 487 0.96

10 12 1e-05 0.00069 20.2 0.1 2 23 494 515 494 515 0.97

11 12 0.0014 0.096 13.4 1.0 1 23 522 544 522 544 0.99

12 12 0.0006 0.04 14.6 3.4 1 23 550 573 550 573 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00049	0.033	14.9	0.6	1	23	205	228	205	228	0.97
2	12	6e-05	0.004	17.8	2.7	1	23	233	256	233	256	0.95
3	12	0.00025	0.016	15.8	4.8	1	23	261	283	261	283	0.98
4	12	8.2	5.5e+02	1.6	5.6	2	23	290	313	289	313	0.89
5	12	0.00056	0.037	14.7	1.0	3	23	323	344	322	344	0.95
6	12	0.0027	0.18	12.6	0.1	1	23	350	373	350	373	0.95
7	12	0.082	5.5	7.9	0.2	5	23	389	408	384	408	0.90
8	12	3.5e-05	0.0023	18.5	0.4	1	23	437	459	437	459	0.98
9	12	1.7e-05	0.0011	19.5	5.3	1	23	465	487	465	487	0.96
10	12	1e-05	0.00069	20.2	0.1	2	23	494	515	494	515	0.97
11	12	0.0014	0.096	13.4	1.0	1	23	522	544	522	544	0.99
12	12	0.0006	0.04	14.6	3.4	1	23	550	573	550	573	0.97

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCCAAATGCGATTTTGAAAATGGCAATAACAACTATTGGCTGGACTTGTTCCATCCAACTCGTTGGCAGAGTGAAATGGCGCAAATACGCTTGGAGATTTCTAACTGGAAGTTACAGATCTCGCCCAGCGATGGACTGCCACAGAAAATATGCAGTGATTGTTTTACAAAGTTCTGCTCCATTTACACTTTTCGATTGGCCTGCCAGGATGCACAGCTGAAGCTGTcgaatatttttgataaaatcgATGCCAACATGCTCTGTGACAAAGCTGAAGATGACCAAGTTGAAGAAGATGCTGATGAaaccgaaacagaaacagaaaaagacactgcaacagcaacaacgacaactacaATAACAGAAAACACTGCCATTATTGAGGCCACAACGCCAACAACTCCCATTGAGATTTATGTGGAAACTATAAACATTAACGAAACAGAGTCACTGCAATTAGATGAGGCAACAGATTACAACTCATTAAACATTAGCTATGCCTGTAAGTTCTGCCACAAGCCACAGGAAAGTTATGAGCTGCAGCATATGCTCCTGGAGCACATTAGTAGCGCCCACGATCCGGACCAGCCCTACAACTGTCCGGAGTGTACAGAGTGCTTCCAGGATGCCGCATCGCGTACAGTTCACATGAAGAACGCACACGTTGTTAAACACTACGCCTGCGAGGTTTGCGGCAAAAAGTACGGAGATCGCCACAATCTGCGACACCATGTCGAGAAATATCATTCGGAAACGGACTTTGAGTGCAGCATGTGCGAGAAGCGTTTCTTCACAAAGAAAAGCCTACACTACCACATGAACTGGCACAATCCGGAGCGTCAGCTGAGATGTAGACACAACGGCTGCGACAGACTGTTCATCAGTCAGCGGCATCTCAAATGTCATGAGGCCACTCACAACGCCGGCTCCCGGAAGAGTGAGTACTGCGGCTTTTGTGGCAAAGCGTTCATTCACGTTAAAACCTTACGCTGGCATATTTATCGGCAACATGGCGGAGAGAAGCCTTTCAAATGTGCCATCTGCACAGAGGTATTTGCATCGTATGCCGAAAAACGCATTCACATGCTTGAGATGCACACGGAGAATCTGACCCATCAGGAACGTAGCGAGTGCATGTTCCAGTCCTGCCGCCAGGAGTTTGACAACGAGCAGGACCTTATCCAGCACATGGCCACGGAGCATTCGCAGCGTGAACCATCAACTCCAATCATTGCGAACAACAAACGGGTGCTCCAACGGAAGCGGGAGCGACAATATACGGGTCTCTTCCAGTGCGGCAGCTGCACCCAACGCTTCAATATGAAATCAGCATTGGAACGCCACATGGCCGTACACTCCGCAGACCGCCTGCACGCCTGTTCGCACTGTTCGAAGCGGTACAAGCGCGCCCAGGACTTAAAGTGGCATATGAAGACGCATTCCAACGAGAAGCCCAATGTTTGTGATGTGTGTGGCAAGGCGTTTGCCCTGAAATATGTACTAACCCAGCACATGCGTAGTCATGAGGTTCTTGAAAAGAACTTTAAGTGTGACACATGTGGACGGGCCTATTTGTTTGAGAAGTCGCTCCGTCTGCATCAGCGTGTTCACACTGGCAATACCTACTACAAATGCGATCTGTGCCAGGAGCGTTTTGTGACTCacatcaaatttaaaaCTCACATGAAAAATGCACACGGCACAAATCAGTCTCTTGCCAAAGATTCGCTGGATGATTTGATCAACATTGTGATTTCCTAA
Protein Sequence: METCRTCAKCDFENGNNNYWLDLFHPTRWQSEMAQIRLEISNWKLQISPSDGLPQKICSDCFTKFCSIYTFRLACQDAQLKLSNIFDKIDANMLCDKAEDDQVEEDADETETETEKDTATATTTTTITENTAIIEATTPTTPIEIYVETININETESLQLDEATDYNSLNISYACKFCHKPQESYELQHMLLEHISSAHDPDQPYNCPECTECFQDAASRTVHMKNAHVVKHYACEVCGKKYGDRHNLRHHVEKYHSETDFECSMCEKRFFTKKSLHYHMNWHNPERQLRCRHNGCDRLFISQRHLKCHEATHNAGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYAEKRIHMLEMHTENLTHQERSECMFQSCRQEFDNEQDLIQHMATEHSQREPSTPIIANNKRVLQRKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSADRLHACSHCSKRYKRAQDLKWHMKTHSNEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCDTCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKNAHGTNQSLAKDSLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00803812;
80% Identity: -