Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: ZNF574
Assembly: GCA_037075165.1
Location: JBAMCL010000620.1:1272233-1274493[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.03 2 9.3 0.5 2 23 334 356 333 356 0.96

2 10 2.9 1.9e+02 3.0 0.2 6 23 366 383 366 383 0.97

3 10 1.7e-05 0.0011 19.5 0.9 1 23 389 411 389 411 0.98

4 10 0.00026 0.018 15.7 0.5 1 21 424 444 424 447 0.87

5 10 6.9e-05 0.0046 17.6 0.6 1 23 455 478 455 478 0.97

6 10 3.2e-05 0.0021 18.6 1.0 3 23 486 507 484 507 0.92

7 10 0.0034 0.22 12.2 0.4 2 23 519 541 518 541 0.97

8 10 0.001 0.068 13.9 7.0 1 23 548 571 548 571 0.93

9 10 2.9e-06 0.0002 21.9 1.2 1 23 577 599 577 599 0.98

10 10 7e-05 0.0047 17.5 1.4 1 23 605 628 605 628 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.03	2	9.3	0.5	2	23	334	356	333	356	0.96
2	10	2.9	1.9e+02	3.0	0.2	6	23	366	383	366	383	0.97
3	10	1.7e-05	0.0011	19.5	0.9	1	23	389	411	389	411	0.98
4	10	0.00026	0.018	15.7	0.5	1	21	424	444	424	447	0.87
5	10	6.9e-05	0.0046	17.6	0.6	1	23	455	478	455	478	0.97
6	10	3.2e-05	0.0021	18.6	1.0	3	23	486	507	484	507	0.92
7	10	0.0034	0.22	12.2	0.4	2	23	519	541	518	541	0.97
8	10	0.001	0.068	13.9	7.0	1	23	548	571	548	571	0.93
9	10	2.9e-06	0.0002	21.9	1.2	1	23	577	599	577	599	0.98
10	10	7e-05	0.0047	17.5	1.4	1	23	605	628	605	628	0.97

Sequence Information

Coding Sequence: ATGGCAGCCTGTGTGCTTTGTTTTGGCTGCTGCAAGATTGGAGAgtcatataaaatattttccgAGGCAGGTTTGCGGCTCAACATTTGCAAAACTATAAACAAGCATTTTTGGCTAGAGCTGAGCAGCGCGAAGGGCGAGCGGGAGGAGATTTGCCGTGAGTGCTGGGAATGCGTGAGCAACTTTAATGAATTCTATCAGCGCGTCTACAATGCACACCAGGAGCGACGCTGCGATGTCAAGAATGTGCCCATCGAGTTTTGTGGGGAGACAGAGGCAGCCAATCCTCTGGCCTTTGGTGCGGAAATGGATGCACTGGCCGAGGACTTCTTTGCGACTGGCGATGTCAAGGTGGAGGTGAACGAACTGGAGCCGCTGCCCAAGCTTGAAATGATTGAGGAGCCAGTGCTTCAGGAAACGAGCACTGCCACAAAGCGCGTCTGTGACGATTACCCTATTAGTGCTAAGCGCCgtgttaaaattaaaaatgagcAGGTGACGGTGCCAAGTGACTCCGATGGGGACATACCGCTGGCCGAGTTCCTGGATCTCAAAAGCGATCCTAAGCCGGCAGCATCAAATAGTAAACAAACGCCAGTCAAGGGCCGCCAGCTGCGTAGAAGCTCGCGACGTGGGCGGCGAGCGAAAACGCCACCAACATCGCCGTCGACCAGCCTAAAAAAGGAGTTTGAATCTGATGATGAGCATGATAATGATAACGACATGGACTTTGTGGCAGCCGAGGCAGTGCTGGGCACTGATGATAGCGCCAGTTCCAGTGAGAGCAGCGATGACGGCTCTGGCGGCAGTTTGCCCGACATAGAGCCCGAGGAGCGCTATGCAGAGATACCCAAACGGGTGATAGTCAAGCCCAAAAAGTATCGCAAACGCCCAAAGCCGCTGGTGCCGCCCGTGCGTATGTCACGGGAGGAAATAGAAAAGCGCAAAGCCCAACAAAACGAGTTCGATAAGATTATATTTGACTTTTTCAAGAAGCTGCCGTGTCACGTATGCAACTTGTTGGTGCCCAATTTTGGCGATATGCGACGCCATCAGCGCATGTCCCACAACATGGAGAGTGGCTTCATAGCTTGCTGTGGCCGCAAGTTTCACATACGCAAGGGTCTGGCCGAGCATGTGCTGGTGCACAAGAATCCTGAGCACTTTATGTGCACGCAATGTGGCCGCGTATTTCAGGACTCAAAAACGCTCGAAACGCAcgagcaaacacacacaaatcctCAGGGTGAAGGAAAGGATAAACGCACCTATCAGTGCGACAAGTGTCCCAAGGTCTTTACAACCAAGGCTGCTGTCGAGTATCACAATGTATCCAAGCATGTGCCCAAGTCGGACTTTAAGTATACCTGCCCCGAGTGCAACAAGAAGGTGCCCACAGAGCGCAAGTTGAGGGAACATTTGCGCTACATGCACGATCCGGAGACTGCCATCATCTGCGATAAGTGCGGCAAGACTTTGCGCTCTCAGGCGAATCTTAAGAAACACCACGAACTGGAGCATTCCGATACGCCACGCCCTAAGCCTGATCCAGTGCAATGCGAAATATGCGGCACCTGGCTGCGCCATTTGTCCGGCCTCAAGCAGCACATGAGCACCGTTCACGAGCCACCCGGCGGCGAGCATCGCTGCCACATCTGCGACAAGAAGTCGACAAATTCGCGCGCACTCAAGCGACACATTTACCACAACCATCAATGCGAAAGAAAGTTCCGTTGCACCATGTGTGAAAAGGCCTTCAAGAGGCCACAGGACTTGAGAGAACACACATCCACGCACACCGGCGAGGTGCTGTACACCTGTCCCAACTGTCCGCAAACGTTCTTTTCCAATGCTAATATGTACAAGCATCGCCAGCGGCTGCATCGCGCCGAATGGGAGGCGGACCGCAAGAAGCCGCTGCCACCCAACATCATGCAACAGGCGGTGGGCGCCACGACGGCAATGAAGAAACGTCAGGCAACCAATGCTGGCCCATCGCTGTTCAATCCATCCGCAGATCCTGCTGCGGATGCCCAGAAACAGGAGCCTCAAATGCgatag
Protein Sequence: MAACVLCFGCCKIGESYKIFSEAGLRLNICKTINKHFWLELSSAKGEREEICRECWECVSNFNEFYQRVYNAHQERRCDVKNVPIEFCGETEAANPLAFGAEMDALAEDFFATGDVKVEVNELEPLPKLEMIEEPVLQETSTATKRVCDDYPISAKRRVKIKNEQVTVPSDSDGDIPLAEFLDLKSDPKPAASNSKQTPVKGRQLRRSSRRGRRAKTPPTSPSTSLKKEFESDDEHDNDNDMDFVAAEAVLGTDDSASSSESSDDGSGGSLPDIEPEERYAEIPKRVIVKPKKYRKRPKPLVPPVRMSREEIEKRKAQQNEFDKIIFDFFKKLPCHVCNLLVPNFGDMRRHQRMSHNMESGFIACCGRKFHIRKGLAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHTNPQGEGKDKRTYQCDKCPKVFTTKAAVEYHNVSKHVPKSDFKYTCPECNKKVPTERKLREHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDTPRPKPDPVQCEICGTWLRHLSGLKQHMSTVHEPPGGEHRCHICDKKSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATTAMKKRQATNAGPSLFNPSADPAADAQKQEPQMR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00803803;
80% Identity: -