Basic Information

Insect: Hirtodrosophila confusa
Gene Symbol: ZNF574
Assembly: GCA_035043065.1
Location: JAWNNI010000242.1:5275337-5277592[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.029 2.3 9.3 0.5 2 23 335 357 334 357 0.96

2 10 2.8 2.3e+02 3.0 0.2 6 23 367 384 367 384 0.97

3 10 1.7e-05 0.0014 19.5 0.9 1 23 390 412 390 412 0.98

4 10 0.00025 0.021 15.7 0.5 1 21 425 445 425 448 0.87

5 10 6.7e-05 0.0055 17.6 0.6 1 23 456 479 456 479 0.97

6 10 3e-05 0.0025 18.6 1.0 3 23 487 508 485 508 0.92

7 10 0.0032 0.27 12.2 0.4 2 23 520 542 519 542 0.97

8 10 0.00098 0.08 13.9 7.0 1 23 549 572 549 572 0.93

9 10 2.8e-06 0.00023 21.9 1.2 1 23 578 600 578 600 0.98

10 10 6.8e-05 0.0056 17.5 1.4 1 23 606 629 606 629 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.029	2.3	9.3	0.5	2	23	335	357	334	357	0.96
2	10	2.8	2.3e+02	3.0	0.2	6	23	367	384	367	384	0.97
3	10	1.7e-05	0.0014	19.5	0.9	1	23	390	412	390	412	0.98
4	10	0.00025	0.021	15.7	0.5	1	21	425	445	425	448	0.87
5	10	6.7e-05	0.0055	17.6	0.6	1	23	456	479	456	479	0.97
6	10	3e-05	0.0025	18.6	1.0	3	23	487	508	485	508	0.92
7	10	0.0032	0.27	12.2	0.4	2	23	520	542	519	542	0.97
8	10	0.00098	0.08	13.9	7.0	1	23	549	572	549	572	0.93
9	10	2.8e-06	0.00023	21.9	1.2	1	23	578	600	578	600	0.98
10	10	6.8e-05	0.0056	17.5	1.4	1	23	606	629	606	629	0.97

Sequence Information

Coding Sequence: ATGGCAGCCTGTGTGCTTTGTTTTGGCTGCTGCAAGATTGGAGagtcatataaaatattttccgaTGCAGGTTTGCGGCTCAACATttgcaaaacaataaacaagcaTTTTTGGCTAGAGCTGAGCAGCGCGAAGGGCGAGCGGGAGGAGATATGCCGCCAGTGCTGGGAATGCGTGAGCAACTTCAATGAATTCTATCAGCGCGTCTACAATGCACACCAGGAACGACGCTGCGATGTCAAGAATGTGCCCATCGAGTTTTGTGGGGAGACAGAGGCAGCCAATCCTCTGGCCTTTGGTGCTGAAATGGATGCACTGGCCGAGGACTTCTTTGCGACTGGCGATGTCAAGGTGGAGGTAAACGAACTGGAACCGCTGCCCAAGCTGGAAATGATTGAGGAGCCAGTGCTTCTTCAGGAATCGAGCACTGCCACAAAGCGCGTCTGTGACGATTACCCCATCAGTGCGAAGCGCCgtgttaaaattaaaaatgagcATGTGACGGTGCCAAGTGACTCCGATGGGGACATACCGCTGGCCGAGTTCCTGGACCTCAAAACCGATCCTAAGCCAGCAGCATCAAATAGTAAACAAACGCCAGTCAAGGGCCGACAGCTGCGTAGAAGCTCGCGACGTGGGCGGCGTGCGAAAACGCCACCAACATCTCCGTCGACCAGCCTTAAAAAGGAGTTTGAAACTGATGATGAGCATGATAATGATAACGACATAGACTTTGTGGCAGCCGAGGCAGTGCTGGGCACTGATGATAGCGACAGTTCCAGTGAGAGCAGCGATGGCGGCTCTGGCGGCAGTTTGCCCGACATAGAGCCAGAGGAGCGGTACGCAGAGATACCCAAACGGGTGATAGTCAAGCCCAAAAAGTATCGGAAACGCCCAAAGCCGCTGGTGCCGCCCGTGCGTATGACTCGGGAGGAAATAGAAAAGCGCAAAGCCCAACAGAACGAGTTCGATAAGATTATATTTGACTTTTTCAAGAAGCTGCCGTGTCACGTTTGCAACTTGTTGGTGCCCAATTTTGGCGATATGCGACGCCATCAGCGCATGTCCCACAACATGGAAAGTGGCTTCATAGCTTGCTGTGGCCGCAAGTTTCACATACGCAAGGGTCTAGCCGAGCATGTGCTGGTGCACAAGAATCCTGAGCACTTTATGTGCACGCAATGTGGCCGCGTATTTCAGGACTCAAAAACGCTCGAAACGCACGAGCAAACACACGCAAATCCTCAGGGTGAGGGAAAGGATAAACGCACCTATCAGTGCGACAAGTGTCCCAAGGTCTTTACAACCAAGGCTGCTGTCGAGTATCACAATGTATCCAAGCATGTGCCCAAGTCGGACTTTAAGTATACCTGCCCCGAGTGCAACAAGAAGGTGCCCACAGAGCGCAAGCTGAGGGAACATTTGCGCTACATGCACGATCCGGAGACTGCCATCATCTGCGATAAGTGCGGGAAAACTTTGCGCTCTCAGGCGAACTTGAAGAAACACCACGAACTGGAGCATTCCGATACGCCACGCCCTAAGCCTGATCCAGTGCAATGCGAGATATGCGGCACTTGGCTGCGCCATTTGTCCGGCCTCAAGCAGCACATGAGCACCGTTCACGAGCCACCCGGCGGCGAGCATCGCTGCCACATCTGCGACAAGAAGTCGACTAATTCGCGCGCACTCAAGCGACACATTTACCATAATCATCAATGCGAAAGAAAGTTCCGTTGCACCATGTGTGAAAAGGCCTTCAAGAGGCCACAGGACTTGAGAGAACACACATCCACGCACACCGGCGAGGTGCTCTACACCTGTCCCAACTGTCCGCAAACGTTCTTCTCAAATGCTAACATGTACAAGCATCGCCAGCGACTGCATCGCGCCGAATGGGAGGCGGACCGCAAGAAGCCGCTGCCCCCAAACATAATGCAACAGGCGGTGGGCGCCACGACGGCAATGAAGAAACGTCAGGCTACCAATGCTGGTCCGTCGCTGTTCAACCCATCCGCTGATCCTGCCACGGACGCCCAGAAGCAGGAGCCTCAAATGCGatag
Protein Sequence: MAACVLCFGCCKIGESYKIFSDAGLRLNICKTINKHFWLELSSAKGEREEICRQCWECVSNFNEFYQRVYNAHQERRCDVKNVPIEFCGETEAANPLAFGAEMDALAEDFFATGDVKVEVNELEPLPKLEMIEEPVLLQESSTATKRVCDDYPISAKRRVKIKNEHVTVPSDSDGDIPLAEFLDLKTDPKPAASNSKQTPVKGRQLRRSSRRGRRAKTPPTSPSTSLKKEFETDDEHDNDNDIDFVAAEAVLGTDDSDSSSESSDGGSGGSLPDIEPEERYAEIPKRVIVKPKKYRKRPKPLVPPVRMTREEIEKRKAQQNEFDKIIFDFFKKLPCHVCNLLVPNFGDMRRHQRMSHNMESGFIACCGRKFHIRKGLAEHVLVHKNPEHFMCTQCGRVFQDSKTLETHEQTHANPQGEGKDKRTYQCDKCPKVFTTKAAVEYHNVSKHVPKSDFKYTCPECNKKVPTERKLREHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDTPRPKPDPVQCEICGTWLRHLSGLKQHMSTVHEPPGGEHRCHICDKKSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATTAMKKRQATNAGPSLFNPSADPATDAQKQEPQMR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00508523;
90% Identity: iTF_00805386;
80% Identity: -