Basic Information

Insect: Hirtodrosophila histrioides
Gene Symbol: zfh1
Assembly: GCA_037075165.1
Location: JBAMCL010000390.1:700362-705324[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.4e-05 0.0023 18.5 1.0 1 23 145 167 145 167 0.97

2 15 0.001 0.069 13.9 1.2 3 23 175 195 173 195 0.94

3 15 0.00011 0.0075 16.9 0.1 1 23 363 385 363 385 0.98

4 15 0.0031 0.21 12.4 2.4 1 23 391 413 391 413 0.98

5 15 0.00051 0.034 14.8 5.2 1 23 444 466 444 467 0.94

6 15 0.003 0.2 12.4 1.8 1 23 509 531 509 531 0.95

7 15 0.022 1.5 9.7 1.3 1 23 537 560 537 560 0.97

8 15 0.033 2.2 9.1 0.4 3 19 569 585 568 586 0.95

9 15 0.0002 0.013 16.1 5.6 1 23 595 617 595 617 0.97

10 15 0.051 3.4 8.5 1.2 2 23 623 644 622 644 0.96

11 15 1.2e-05 0.00077 20.0 1.0 1 23 653 675 653 675 0.98

12 15 0.0013 0.087 13.5 0.1 3 23 683 703 681 703 0.97

13 15 7e-05 0.0047 17.5 0.5 1 23 709 731 709 732 0.95

14 15 0.064 4.3 8.2 0.4 1 23 742 764 742 764 0.97

15 15 0.00017 0.012 16.3 0.6 1 23 1279 1301 1279 1301 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.4e-05	0.0023	18.5	1.0	1	23	145	167	145	167	0.97
2	15	0.001	0.069	13.9	1.2	3	23	175	195	173	195	0.94
3	15	0.00011	0.0075	16.9	0.1	1	23	363	385	363	385	0.98
4	15	0.0031	0.21	12.4	2.4	1	23	391	413	391	413	0.98
5	15	0.00051	0.034	14.8	5.2	1	23	444	466	444	467	0.94
6	15	0.003	0.2	12.4	1.8	1	23	509	531	509	531	0.95
7	15	0.022	1.5	9.7	1.3	1	23	537	560	537	560	0.97
8	15	0.033	2.2	9.1	0.4	3	19	569	585	568	586	0.95
9	15	0.0002	0.013	16.1	5.6	1	23	595	617	595	617	0.97
10	15	0.051	3.4	8.5	1.2	2	23	623	644	622	644	0.96
11	15	1.2e-05	0.00077	20.0	1.0	1	23	653	675	653	675	0.98
12	15	0.0013	0.087	13.5	0.1	3	23	683	703	681	703	0.97
13	15	7e-05	0.0047	17.5	0.5	1	23	709	731	709	732	0.95
14	15	0.064	4.3	8.2	0.4	1	23	742	764	742	764	0.97
15	15	0.00017	0.012	16.3	0.6	1	23	1279	1301	1279	1301	0.98

Sequence Information

Coding Sequence: ATGAACAATCAGGACTATGGCGGCATCCAATGGATACAGCAGCACGCAACCGACGATATGCTGCAAGGCGCCTCCGCCGACGGTGAGGTGACGTCCGCTTATCTGGTCAGTGGCAATGCAACCGACGAGGATCTCGATCAAATGGCCGCCGAGAATCTCATCTTCATGGCCCGCGATGGCCAGCTGACCGAGATCATAGCCGCCAACGAGTCTGGCAGCGGCACCGTGCTCATCACGGACAGCGGCACCGTCGCATATGCGGAGTCATTTGACGATGATGCCCAGGTGGTCACCGAGGAGATCATCACTGATGATTGGGTGCAGCATCAGGGCGCCGAGCGCGTGGAAATTGCTGCCGAGCAAATAGCTGGAAACAGCAGCTCACTGGAGCTGCTGGATATGGAGCAGGACGAGTATACGGCGCTGCGTCCTTATCCCTGTGACTTCTGTAGCCGGCGCTTTCGCAAGAAGGCCAGCCTCAATAATCATATGCTGGCGCATCAAAACGATCGTCCGCATCTGTGTAAGCTTTGTGGTGCGCGCTTTTCGCGTCGCGCCGAGCTCATCAGTCATTTTAAGGCGCATGCCGAGGCACAGGACGCTGCGGACGCGGAAGCCGCCGCGGCGTCGTCAGTGTCAGCAGCTAATATAAAATTCGAGccgcagcagcaccagcaacagcatcaaaCACAAATCGATGATCACTTCTACGAACAGGAATGGCCTTCATatcaggaacaggaacaggatcaggaacaacaactggaccaggagcaggagcagttGCCTATTGCCAGCCATGTTGCGCAGTCGGCCTGCTATGCAGCGGTTAGCGCTGTGGCAGCGCCAACAGCAGCGCGCGGACGCATTAGTCGCCTCAAGCCCAAGGAGGAGAGCACACAGTACATTGTGATTGCCGAAAAGCAAACCTCTGACGACTTGCCACAGTATATGGATTCCGAAGAGCTACCGCCGCCGTTAACTGCCAACACAACGTCGCTCGATGCGACCCACACGACAGACGGTGGCCCAGTCGCTATTGCAGCACATCCGCCACGTTTCCCCGTGATCGACGACAGCAAACCCTTTGTCTGCCAGCAGTGCGGCTTGGCATTTGCGCGCGAAAAAGCGCTTGTTTCCCATATTAAGAATCATCGCGTGGACTCTCCGTTTGAGTGTAACCAGTGTCAGGAGATGTTTTGGGACAATTACAGCCTGCATGAGCATCAGAAGACGCATCAGTTTGAGGAGAGCAACTCAGAGTACGATCCAGCGTCGGCGGGGGAGGATAGCGCCAGCGAATCGGAGTCAGAACAGCTTTATGGTGAATTTTTCTGCAGCGAGTGTGGCATATCCTTTCACAGGCAGGACCTGCTGCGCCGCCATAGCAAGCAGCACCACAAACTGGCCGCAGCTAATGCTGCGGCTACGCTCAACTCAACAGATGTGGAGGGCAGCGCCGATGCCGATGCTGATGCCGACGCCGAtcctgatgctgatgctgagaATGCCAAAGATGCGCCGCACTGCTGTCATACCTGCGGCAAATCCTATCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCACGCACGCTTTCCACCATTCAAATGTGTGTTGTGCGGTGTTAGTTTTTATGAGGAGCAAGCCATTAAGCGGCATCTGCACACCCGTCATCCACACGAACTCAAGCCGAACTCTTGCGTGCTGTGCGGCAAGGAGTGCCGCGATCGCAAGGCGCTGATCAAGCATGCCTGGGATCACTCGCGCGAGAAGTGCCACTCGTGCTCCAAATGCGGCAAGAACTTTCACAACAAGGCGCGCTTGAAGCGGCATATGGCCTCGCATCGCGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTTCCCGATGGCCGCACGCTATCCAATCACCGCCATTCGCACAGCACAACCTCACCGGGTAAACTGTTCCCCTGCCATGAGTGCGGCAAGACCTTTGGCTCTCGCAGCTCGCAGCAGATTCATGTGCGCATTCATACCGGCGAGCGGCCATATGGTTGCCGCTACTGCTGGAAGGCCTTCGCCGATGGAGGCACGCTCCGCAAGCACGAGCGCATACATACTGGGGAGAAGCCCTATGCCTGCTCCGTTTGTCCACGTGCCTTTAATCAGCGTGTGGTGCTGCGCGAGCATATACGCTCGCATCACTCGGGGCTGGATGCGGAGCGTGGCACCTATCACTGCACCGTCTGCACGGCAGACTTGTCCTCATCCAATGAGCTAATACAGCATCTCATTCAACACAGCGACACAAACACCGCCAAACAGCGACAGCCTATTACCGGACCCCGCAAGTACAAGCGTCGTAGGAAACTGCAGCCCCATGAGATAGCACACCTGCGAGCCGAACACAAGGACGGCGATGAATATGCCAGCGACATTGATCTCTGCGATTTGGATGTGGAGAATGTGGACGATCTCTTTGATGGGGAAGAGCCATCCCCACCCAAAAAGGAGAAGCGCAAGCGTAACGCAGCAGGTCAAGCTAAGAACGTGGTCAATGGTGATGCAGCGCCCGCCCAAAACAACTCTGTTGCAGTCAAATCCGCGAATGGCAATTCAGATCGTCTGTGGGAGGATAAATTCATGCAGGcaaatggcaacggcaacgttGGCAATCAGCTAAATGATGATGCCTACAAGAGCCTCTATCAGATCGATTCGCTGGTGGTGGTTAATGATACCACGCTGCAGCCAGTAAGCTCATCTAGTGGTATGGCCAAGACGCGACGCAGTGGCAAGCAGCCACAGACGCAGCGGCTGACGCAAGCCGACAACAGCGACAAGTCAGAAGCAATGGCTACTGATGAGTATGGCAAACCCAGCAACTCCTCTACCTccagcagtcgcagcagcagaaagAAGACTGGCAAGGCGTCCAAGAATGCAGCCACAACAGCGTCCACTTCCAGCAGCTCGCGTCCACGTATGATACACACTGAAAAGTCACGCGTGCCACAGGAACATGCGTCAAAGAAGACGCGAAACCGGACTTACATCACGCGCACCAGCGAGAGCAGCCAGCTGGGTCTGGTCAAGTCGCGCATTGTGGATGACTACGAAATTATTTCACCTGCCACTCAGCCACCAAATCAGATAAGCTCCAGTCCGCTGCATATtaagcaggagcaggagcagcagcgcgTGCAGCTTATGTATGATGATACGCATCTTCTTATCGATACGGCTCTGTTGCGGGAGAAGACCTATGAGAAGTTTAATCCCAGCATTGTCAATGATCTTGAGGAGATACTGCGTAGTCCTCTCAAACATGATCGCAATGCGCGACTTCGTTTCACCAGCGAATCGTCGACAACGCCACAGTTTTTGCCCGAGGAGGAGCAGAACCTTATTAAAATAGAGCCGACGTCGCCAGATCTGCGTGAAATGGTTGAGAGCCAGCAGCGCGTCACTGCCACAGGCCACACAGCCACAACCAGGACATCGTCGTCGGCGGTGCGCAACTCGCGCCATCTGCGACAGCTTACTGCCAACTCAAGCTCACGAGCAGCAAcaaagcgcagcagcagcagcaaattagTTTCTGCATCCAGTTCCAAGAAATCAAACGTCAATTCATCCTCTTCCGTTGCAGAGAGCAAAGCGTCCAATTCTTACCTGAGCTATGGCGTTGACTCGTACAATGTGAACGTAGCTGCCAGCGCAAACTCTTCAGATGTTAGCTCCGGTTTCTTTTCCATTTCTGAGGTAGTATCCGCTGCAGATGCTGCCGATGCAGCGGCTAAGGCAGCAGCGGCCAACAAAACGGAGCGCAGGACGCGTTGCTTTGAGTGTGAAATGTGCTCGACCAAATTTCCGGATCGTGCCCAGCTTTTAGatcatatgcatatacacatctaa
Protein Sequence: MNNQDYGGIQWIQQHATDDMLQGASADGEVTSAYLVSGNATDEDLDQMAAENLIFMARDGQLTEIIAANESGSGTVLITDSGTVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNSSSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAASSVSAANIKFEPQQHQQQHQTQIDDHFYEQEWPSYQEQEQDQEQQLDQEQEQLPIASHVAQSACYAAVSAVAAPTAARGRISRLKPKEESTQYIVIAEKQTSDDLPQYMDSEELPPPLTANTTSLDATHTTDGGPVAIAAHPPRFPVIDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLHEHQKTHQFEESNSEYDPASAGEDSASESESEQLYGEFFCSECGISFHRQDLLRRHSKQHHKLAAANAAATLNSTDVEGSADADADADADPDADAENAKDAPHCCHTCGKSYPSALELLAHAEIHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAERGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHLRAEHKDGDEYASDIDLCDLDVENVDDLFDGEEPSPPKKEKRKRNAAGQAKNVVNGDAAPAQNNSVAVKSANGNSDRLWEDKFMQANGNGNVGNQLNDDAYKSLYQIDSLVVVNDTTLQPVSSSSGMAKTRRSGKQPQTQRLTQADNSDKSEAMATDEYGKPSNSSTSSSRSSRKKTGKASKNAATTASTSSSSRPRMIHTEKSRVPQEHASKKTRNRTYITRTSESSQLGLVKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQLMYDDTHLLIDTALLREKTYEKFNPSIVNDLEEILRSPLKHDRNARLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTATGHTATTRTSSSAVRNSRHLRQLTANSSSRAATKRSSSSKLVSASSSKKSNVNSSSSVAESKASNSYLSYGVDSYNVNVAASANSSDVSSGFFSISEVVSAADAADAAAKAAAANKTERRTRCFECEMCSTKFPDRAQLLDHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00803765;
80% Identity: -